Multiple lentigines in areas of resolving psoriatic plaques after ustekinumab therapy.
We report the case of a patient that developed multiple lentigines after clearance of the plaques of psoriasis receiving treatment with ustekinumab for his psoriasis. PMID: 24746301 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Guttierez-Gonzalez E, Batalla A, De la Mano D Tags: Dermatol Online J Source Type: research

Primary milia localized to the vulva.
This report demonstrates the unique presentation of primary milia in the genital region and explores the diagnostic features and treatment methods of these lesions. PMID: 24746302 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Adotama P, Susa J, Glass Ii DA Tags: Dermatol Online J Source Type: research

Follicular unit extraction with the Artas robotic hair transplant system system: an evaluation of FUE yield.
Abstract Hair transplants were developed and championed by dermatologists. However, dermatology literature has few contributions from within our specialty. In this manuscript, we present our evaluation of a specific graft harvesting approach for hair transplants referred to as Follicular unit extraction (FUE). In particular, we sought to evaluate the rate of harvest attempts that did not produce an actual hair folliclular unit graft. PMID: 24746303 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Rashid RM Tags: Dermatol Online J Source Type: research

Secondary mucinous carcinoma of the skin.
We report a case of a woman who presented with a cystic-appearing nodule on her left nipple. After cutaneous biopsy and gynecological staging study, she was diagnosed with skin invasion of mucinous carcinoma of the breast. We describe the main features of this rare tumor and the controversies in its diagnosis because primary and metastatic mucinous carcinomas in skin are histologically indistinguishable. PMID: 24746304 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Frances L, Cuesta L, Leiva-Salinas M, Banuls J Tags: Dermatol Online J Source Type: research

Top dermatologic diagnoses by age.
Conclusion: Dermatologic conditions seen in different age groups and between dermatologists and non-dermatologists vary. With advancing age, Americans increasingly seek a dermatologist rather than a non-dermatologist physician for skin conditions. PMID: 24746305 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Landis ET, Davis SA, Taheri A, Feldman SR Tags: Dermatol Online J Source Type: research

Lymphomatoid papulosis and recurrent transitional cell carcinoma of the bladder: a paraneoplastic association.
We present a 79-year-old man with lymphomatoid papulosis and transitional cell carcinoma of the bladder. PMID: 24746306 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Leon W, Aw C, Tran K Tags: Dermatol Online J Source Type: research

Edematous lip in a HIV patient on highly active antiretroviral therapy.
Abstract A 59-year-old HIV-positive, hepatitis C positive man on highly active antiretroviral therapy presented with a 2-year history of extreme swelling of the lower lip. Granulomatous cheilitis was diagnosed. PMID: 24746307 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Thorpe R, Lopez I, Tran K Tags: Dermatol Online J Source Type: research

A perforating pilomatricomal horn on the arm of an 11-year-old girl.
We present a case of a perforating pilomatricoma presenting as a cutaneous horn in an 11 year old girl. PMID: 24746308 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Kost DM, Smart DR, Jones WB, Bain M Tags: Dermatol Online J Source Type: research

An atlas of the morphological manifestations of hidradenitis suppurativa.
This article is dermatological atlas of the morphologic presentations of Hidradenitis Suppurativa (HS). It includes: superficial abscesses (boils, furnucles, carbuncles), abscesses that are subcutaneous and suprafascial, pyogenic granulomas, cysts, painful erythematous papules and plaques, folliculitis, open ulcerations, chronic sinuses, fistulas, sinus tracts, scrotal and genital lyphedema, dermal contractures, keloids (some that are still pitted with follicular ostia), scarring, skin tags, fibrosis, anal fissures, fistulas (i.e. circinate, linear, arcuate), scarring folliculitis of the buttocks (from mild to cigarette-li...
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Scheinfeld N Tags: Dermatol Online J Source Type: research

Successful treatment of pityriasis rubra pilaris with adalimumab - case report.
We report the case of a 51 year- old man with a clinical and histopathological diagnosis of PRP. He underwent therapy with adalimumab and showed clearance of skin lesions within the fourth week of treatment. PMID: 24746310 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Bravo EA, Carrion L, Paucar SM, Mendoza R, Rivera C Tags: Dermatol Online J Source Type: research

Descripción de un caso de sarcoidosis liquenoide con hallazgos clínicos e histopatológicos característicos.
We report a patient with a one month history of an eruption of skin colored papules. Some were grouped in a symmetrical distribution on the trunk, inner arms, and lumbar region. Pathologic examination revealed an infiltrate in the papillary dermis showing a band of noncaseating granulomas along with disruption of the basal lamina and lichenoid changes. The clinicopathological correlation confirmed the diagnosis of lichenoid sarcoidosis. We consider our case interesting owing to the clinical presentation and the lichenoid distribution of granulomas. PMID: 24746311 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Sanchez-Lopez J, Porriño-Bustamante ML, Aneiros-Fernández J, Naranjo-Sintes R, Fernández-Pugnaire MA Tags: Dermatol Online J Source Type: research

Erythema nodosum - a review of an uncommon panniculitis.
Abstract Panniculitis, inflammation of the subcutaneous fat, is a relatively uncommon condition that usually presents with inflammatory nodules or plaques. Erythema nodosum (EN) is clinically the most frequent form of panniculitis and is considered a reactive process that may be triggered by a wide variety of stimuli. Whilst up to 55% of EN is considered idiopathic, the most common causes include infections, drugs, systemic illnesses such as sarcoidosis and inflammatory bowel disease, pregnancy, and malignancy. EN typically presents in the teens and 20s, and is seen more commonly in females. It is often preceded b...
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Blake T, Manahan M, Rodins K Tags: Dermatol Online J Source Type: research

Acantose nigricante maligna: realato de caso.
Abstract Os autores apresentam um caso de uma paciente de 44 anos , tabagista, com dermatose disseminada diagnosticada como acantose nigricante. As lesões da pele levaram ao diagnostico de metátase de carcinoma provavelmente de origem pulmonar, localizado na região laringofaringea, até então assintomatico. PMID: 24746313 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - April 27, 2014 Category: Dermatology Authors: Lazzarini R, Simone K, Queiroz G, Courral I, Magliari ME, Feder CK, Lellis R Tags: Dermatol Online J Source Type: research

Adult-onset reticulohistiocytoma presenting as a solitary asymptomatic red knee nodule: report and review of clinical presentations and immunohistochemistry staining features of reticulohistiocytosis.
Abstract Reticulohistiocytomas are benign dermal tumors that usually present as either solitary or multiple, cutaneous nodules. Reticulohistiocytosis can present as solitary or generalized skin tumors or cutaneous lesions with systemic involvement and are potentially associated with internal malignancy. A woman with a solitary red nodule on her knee is described in whom the clinical differential diagnosis included dermatofibroma and amelanotic malignant melanoma. Hematoxylin and eosin staining and immunoperoxidase studies of the biopsy specimen established the diagnosis of adult-onset reticulohistiocytoma (solitar...
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Cohen PR, Lee RA Tags: Dermatol Online J Source Type: research

Resolution of recalcitrant pyogenic granuloma with laser, corticosteroid, and timolol therapy.
We report a recalcitrant case of chronic pyogenic granuloma occurring on the scalp of a healthy young male which was unresponsive to conventional surgical and non-surgical modalities. Ultimately, aggressive laser therapy, intralesional triamcinolone acetonide injections, and topical timolol application led to complete resolution and healing. PMID: 24656264 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Millsop JW, Trinh N, Winterfield L, Berrios R, Hutchens KA, Tung R Tags: Dermatol Online J Source Type: research

Disseminated ulcerating lupus panniculitis emerging under interferon therapy of hairy cell leukemia: treatment or disease-related?
We report a 43-year old woman, who underwent therapy with interferon-α for hairy cell leukemia. During interferon-α therapy she developed multiple subcutaneous swellings, accompanied by fever and fatigue. A skin biopsy revealed lobular, T-cell lymphocytic panniculitis. In conjunction with the clinical and immunological findings the diagnosis of lupus panniculitis was made and interferon-α therapy stopped. Initially she responded well to oral prednisone and hydroxychloroquine, but after several months she became resistant to it. Her condition worsened and she developed skin ulcers in the inflamed regions. ...
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Urosevic-Maiwald M, Nobbe S, Kerl K, Benz R Tags: Dermatol Online J Source Type: research

Adenoid cystic carcinoma of the base of the tongue metastasizing to the scalp.
We present a 76 year-old white man with a history of adenoid cystic carcinoma from the base of the tongue diagnosed 15 years prior to the development of the metastatic lesion on his mid-posterior scalp. The present case represents the second reported instance of an extracutaneous adenoid cystic carcinoma metastasizing to the scalp. Differentiating between a primary cutaneous adenoid cystic carcinoma and an extracutaneous adenoid cystic carcinoma metastasizing to cutaneous structures is crucial in determining prognosis and management. PMID: 24656266 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Saco M, Howe N, Jukic DM, Muro-Cacho C Tags: Dermatol Online J Source Type: research

UVB-Sensitive solar urticaria possibly associated with terbinafine.
This report describes the first patient with possible terbinafine-associated solar urticaria. PMID: 24656267 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Kuo S, Sivamani RK Tags: Dermatol Online J Source Type: research

Follicular unit extraction hair transplant harvest: a review of current recommendations and future considerations.
Abstract Alopecia affects many individuals worldwide. Owing to the large role that hair loss plays in self-image and self-confidence, an increasing number of these men and women seek options for hair restoration.Major considerations and sources of hesitation for strip surgical restoration are the visible linear scar, prolonged downtime, and other expected side effects of invasive procedures. These problems can be circumvented by smaller harvest approaches. However, the traditional punch harvest, which produces no linear scar, does leave patients with an often-unsatisfactory "doll hair" appearance. Follic...
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Bicknell LM, Kash N, Kavouspour C, Rashid RM Tags: Dermatol Online J Source Type: research

Angiolymphoid hyperplasia with eosinophilia of the infra-axillary region: report of a case.
Abstract Angiolymphoid hyperplasia with eosinophilia is an uncommon, benign hyperproliferative disorder. Papules and nodules occur predominantly in the head and neck region. Involvement of other sites such as the trunk and mucosae has been rarely reported. We herein report a case of angiolymphoid hyperplasia with eosinophilia involving the right infra-axillary region. PMID: 24656269 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Parmar NV, Sandu J, Kanwar AJ, Saikia UN Tags: Dermatol Online J Source Type: research

Multinucleate cell angiohistiocytoma: a new case report with dermoscopy.
We report a 48-year-old man with asymptomatic grouped reddish papules on the dorsum of his right hand for 8 years. Histopathological and immunohistochemical examinations revealed features of MCA with a fibrohistiocytic cell infiltrate in the dermis and multinucleate cells in the stroma. Recently, the dermoscopy aspects of MCA have been described. We add another observation of this useful tool and correlate it with clinical evolution. PMID: 24656270 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Teixeira V, Serra D, Pereira N, Tellechea O Tags: Dermatol Online J Source Type: research

Acral Persistent Papular Mucinosis: is it an under-diagnosed disease?
We present a female with both the clinical and histopathological described criteria. PMID: 24656271 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Alvarez-Garrido H, Najera L, Garrido-Rios AA, Cordoba-Guijarro S, Huerta-Brogeras M, Aguado-Lobo M, Borbujo J Tags: Dermatol Online J Source Type: research

Erythematous nodular lesion on the chest of an infant.
Abstract An 11-month-old girl presented with an erythematous nodule on the chest, which had been growing for 8 months. The tumor was composed of uniform polygonal and spindle-shaped cells, forming nodules and fascicles. The diagnosis of neurothekeoma was based upon the histology and immunohistochemistry. PMID: 24656272 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Grillo E, Perez B, Paoli J, Carrillo R, Jaen P Tags: Dermatol Online J Source Type: research

"Angular" plasma cell cheilitis.
We report a case of Plasma cell angular cheilitis in a 58-year-old male, localized in the lateral oral commissure. PMID: 24656273 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Da Cunha Filho RR, Tochetto LB, Tochetto BB, De Almeida HL, Lorencette NA, Netto JF Tags: Dermatol Online J Source Type: research

Linear and whorled nevoid hypermelanosis with dermatoscopic features.
Abstract Linear and whorled nevoid hypermelanosis (LWNH) is a rare sporadic disorder, characterized by hyperpigmented, reticulated, streaky, and whorled macules along Blaschko lines. Herein we report a 33-year-old male presenting with linear and whorled nevoid hypermelanosis.There was no family history. Dermatoscopy revealed a net like pattern. This case is been presented for its rarity and for its dermatoscopic pattern. PMID: 24656274 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Naveen KN, Reshme P Tags: Dermatol Online J Source Type: research

Lack of information in current guidelines regarding systemic corticosteroids in inflammatory diseases.
Abstract The use of systemic steroids for inflammatory diseases is a controversial issue-one that continuously invites disagreement throughout the healthcare community. However, there is little, if any, mention of systemic steroid recommendations among widely used rheumatoid arthritis, psoriasis, and psoriatic arthritis guidelines. This relative dearth of information is contrasted by the pervasive systemic steroid use for decades both domestically and abroad [1,2]. The European League Against Rheumatism (EULAR) guidelines for rheumatoid arthritis discuss systemic steroid use, though relatively briefly [3]. The mos...
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Semble AL, Davis SA, Feldman SR Tags: Dermatol Online J Source Type: research

Are topical keratolytic agents needed in the treatment of scalp psoriasis?
Conclusion: High potency topical corticosteroids are usually effective in treating scalp psoriasis in clinical trials. Poor efficacy in clinical practice may be owing to poor adherence to the treatment regimen. Using a keratolytic agent in conjunction with a topical corticosteroid may provide marginal additional benefit in clinical trials, but that benefit is likely outweighed by the downside of complicating treatment and reducing adherence in the clinical setting, unless a single product containing both medications were used. PMID: 24656276 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Shokeen D, O'Neill JL, Taheri A, Feldman SR Tags: Dermatol Online J Source Type: research

Acne vulgaris in the context of complex medical co-morbities: The Management of Severe Acne Vulgaris in a Female with Retinitis Pigmentosa- Utilizing Pulse Dye Laser in Conjunction with Medical Therapy.
We present a patient with severe acne vulgaris and a history of retinitis pigmentosa who was treated with 595 nanometer pulsed dye laser therapy, in conjunction with therapeutic alternatives to first-line acne medications. Our patient exhibited a significant and sustained improvement with the combined use of 595 nanometer pulsed dye laser, Yaz (drospirenone-ethinyl estradiol), dapsone, topical metronidazole, sodium-sulfacetamide wash, and topical azelaic acid. The positive results in this case, suggest that this combined treatment modality may serve as an example of a safe and effective treatment alternative in the managem...
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Shariff A, Keck L, Zlotoff B Tags: Dermatol Online J Source Type: research

A case of a patient with stage III familial hidradenitis suppurativa treated with 3 courses of infliximab and died of metastatic squamous cell carcinoma.
Abstract Although rare, severe hidradenitis suppurativa (HS) of the anal, perianal, gluteal, thigh, and groin regions can evolve into squamous cell carcinoma (SCC). This usually does not occur until the HS has been present for more than 20 years. Malignant degeneration of HS in the axilla has not been reported. SCC has developed in dissecting cellulitis, acne conglobata, and pilonidal cysts (other members of the follicular tetrad). Whereas the male to female ratio of HS is 1:3, SCC in HS has a male to female ration of 5:1. The reasons behind malignant degeneration in HS are complex and might differ from the malign...
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Scheinfeld N Tags: Dermatol Online J Source Type: research

Herpes zoster duplex bilateralis.
Abstract Disseminated herpes zoster has been defined by some authors as a generalized eruption of more than 20 lesions beyond the primary or adjacent dermatomes, usually within a week of clinical manifestation of the primary lesion. In the case described by Takaoka et al. the two lesions presented simultaneously with no evidence of widespread eruption. Perhaps the term, disseminated should not have been employed in this situation. PMID: 24656279 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Chernev I Tags: Dermatol Online J Source Type: research

Scalp sarcoidosis: a sign of systemic sarcoidosis.
Abstract Sarcoidosis is a systemic disease often with cutaneous manifestations. Scarring alopecia of the scalp is a rare form of cutaneous sarcoidosis. Herein, we describe a case of sarcoidosis of the scalp mimicking discoid lupus. PMID: 24656280 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Cheraghi N, Robinson A, O'Donnell P, Belazarian L Tags: Dermatol Online J Source Type: research

Summary of the Dutch S3-Guidelines on the treatment of psoriasis 2011.
ger MM, Thio HB, Torcque LA, De Vries AC, Van de Kerkhof PC, Spuls PI Abstract This document provides a summary of the Dutch S3-guidelines on the treatment of psoriasis. These guidelines were finalized in December 2011 and contain unique chapters on the treatment of psoriasis of the face and flexures, childhood psoriasis as well as the patient's perspective on treatment. They also cover the topical treatment of psoriasis, photo(chemo)therapy, conventional systemic therapy and biological therapy. PMID: 24656281 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 28, 2014 Category: Dermatology Authors: Zweegers J, De Jong EM, Nijsten TE, De Bes J, Te Booij M, Bogonjen RJ, Van Cranenburgh OD, Van Deutekom H, Van Everdingen JJ, De Groot M, Van Hees CL, Hulshuizen H, Koek MB, De Korte WJ, De Korte J, Lecluse LL, Pasch MC, Poblete-Gutierrez PA, Prens EP, Se Tags: Dermatol Online J Source Type: research

A slowly enlarging mass on the finger.
Abstract An otherwise healthy 71-year-old woman presented with an asymptomatic mass on her right 4th finger that had been slowly enlarging over the past 2 years. On physical examination, there was a tan-pink, freely mobile, rubbery, 9-mm papule with a central keratotic plug located over the extensor aspect of the proximal interphalangeal joint of the right 4th finger. A 3-mm punch biopsy of the lesion was performed. Histopathologic findings were consistent with a diagnosis of aggressive digital papillary adenocarcinoma (ADPAca), an adnexal tumor with high metastatic potential that is unfortunately initially misdia...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Jefferson J, Thompson C, Rich P Tags: Dermatol Online J Source Type: research

Patient satisfaction in dermatology: a qualitative assessment.
The objective of this study was to determine factors essential to patient satisfaction in dermatology. Qualitative data from an online survey were collected and organized thematically. Themes studied include the character of the physician, communication, time, care, and qualities of the office staff. Doctors with good character who communicated effectively and spent sufficient time with patients received high satisfaction. An efficient and friendly office staff also contributed to high satisfaction. Poor patient satisfaction was mainly linked to flaws in physician demeanor, lack of communication, and rushed appointments. A...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Ali ST, Feldman SR Tags: Dermatol Online J Source Type: research

Patient satisfaction in dermatology: a qualitative assessment.
The objective of this study was to determine factors essential to patient satisfaction in dermatology. Qualitative data from an online survey were collected and organized thematically relying on a previously established coding scheme for patient satisfaction comments. Themes studied include the character of the physician, communication, time, care, and qualities of the office staff. Doctors with good character who communicated effectively and spent sufficient time with patients received high satisfaction. An efficient and friendly office staff also contributed to high satisfaction. Poor patient satisfaction was mainly link...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Ali ST, Feldman SR Tags: Dermatol Online J Source Type: research

Subcutaneous panniculitis-like T-cell lymphoma with unusual eschar-like crusting.
We describe herein a case of a young woman who presented with intermittent fever and skin rash and was diagnosed later with SPTCL. The case is reported here for its rarity and rapidly changing unusual clinical manifestations. This case also highlights that monotherapy with systemic steroid can be a valuable treatment option for the management of SPTCL, especially in those without hemophagocytic syndrome. PMID: 24612568 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Ghosh SK, Roy D, Mondal P, Bhunia D, Dutta D Tags: Dermatol Online J Source Type: research

Why sulfonamides are contraindicated in Rocky Mountain spotted fever.
Abstract Sulfonamide antibiotics are not effective for the treatment of Rocky Mountain spotted fever (RMSF). Patients suspected of having RMSF based on history and physical exam should be treated with doxycycline and not a sulfonamide to avoid increased morbidity and mortality. PMID: 24612569 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Ren V, Hsu S Tags: Dermatol Online J Source Type: research

Compliance with follow-up among patients with melanoma and non-melanoma skin cancers.
Conclusions: Patient compliance with physician recommended follow-up regimens is generally poor; further research and intervention is necessary to identify and address the underlying causes. PMID: 24612570 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Kalimullah FA, Brown CW Tags: Dermatol Online J Source Type: research

A slowly enlarging mass on the finger.
Abstract An otherwise healthy 71-year-old woman presented with an asymptomatic mass on her right 4th finger that had been slowly enlarging over the past 2 years. On physical examination, there was a tan-pink, freely mobile, rubbery 9-mm papule with a central keratotic plug located over the extensor aspect of the proximal interphalangeal joint of the right 4th finger. A 3-mm punch biopsy of the lesion was performed. Histopathologic findings were consistent with a diagnosis of aggressive digital papillary adenocarcinoma (ADPAca), an adnexal tumor with high metastatic potential that is unfortunately commonly misdiagn...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Jefferson J, Thompson C, Rich P Tags: Dermatol Online J Source Type: research

Erlotinib induced target-like purpura.
Abstract Erlotinib is an epidermal growth factor receptor (EGFR) inhibitor, used as a treatment for advanced stage cancer. The most common side effect is cutaneous toxicity including the already known papulopustular reaction. We herein report a case of erlotinib induced target-like purpura, a peculiar cutaneous adverse event. A 57-year-old patient with advanced non-small cell lung cancer was treated by erolotinib 150 mg daily. After taking the drug for three days, an unusual target-like purpura developed on her lower legs. Skin biopsy specimen taken from the lesion revealed an extravasation of erythrocytes in the ...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Rungtrakulchai R, Rerknimitr P Tags: Dermatol Online J Source Type: research

A case of harlequin ichthyosis treated with isotretinoin.
Abstract Harlequin ichthyosis is a rare congenital ichthyosis classified under the category of Autosomal Recessive Congenital Ichthyoses, which also include lamellar ichthyosis and congenital ichthyosiform erythroderma. It is caused by functional null mutations in the ABCA12 gene, a keratinocyte lipid transporter associated with lamellar granule formation. Patients have a classic clinical presentation at delivery and need neonatal intensive care treatment to maximize their chances of survival. Early oral retinoid therapy has been shown to increase survival in patients with harlequin ichthyosis[1], and we present a...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Chang LM, Reyes M Tags: Dermatol Online J Source Type: research

Cutaneous metastasis of a transitional cell carcinoma.
We describe a rare case of a urolethial carcinoma metastatic to the skin in an elderly female. The metastasis expanded rapidly and was thought to possibly be infectious on her initial evaluation by her primary team. We were called in as consultants and biopsied this mass to confirm our concern for metastatic disease. In this case there was an unknown primary tumor. Histologic staining patterns were used to suggest that the tumor may have originated from her urinary bladder. PMID: 24612574 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Schmiedecke R, Perry A, Satter EK Tags: Dermatol Online J Source Type: research

Oral compound nevus.
Abstract The melanocytic nevus is a benign and focal proliferation of nevus cells that can be congenital or acquired. Intraoral lesions are uncommon, and the etiology and pathogenesis are poorly understood. The occurrence rate of oral compound nevus is about 5.9% to 16.5% of all oral melanocytic nevi. A 22-year-old male patient presented with a dark brown macule on the buccal mucosa of the maxilla in the region of tooth 26. The lesion was elliptical, 0.7 x 0.5 cm, well circumscribed, asymptomatic, and the evolution time was unknown. An excisional biopsy was performed and microscopic analysis revealed nests of nevu...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Cardoso LB, Consalaro A, Da Silva Santos PS, Da Silva Sampieri MB, Tinoco-Araujo JE Tags: Dermatol Online J Source Type: research

Dermoscopy in Merkel cell carcinoma: a case report.
We report the case of an 82-year old woman with a Merkel cell carcinoma on the face. Clinical and histopathological features are presented. In addition, dermoscopic features and the differential diagnosis of this rare tumor are discussed. Although nodules with atypical dermoscopic vascular pattern and milky-red areas will end up being excised, this report adds more clues to the rarely described dermoscopic morphologic presentation of MCC. PMID: 24612576 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Laureano A, Cunha D, Pernandes C, Cardoso J Tags: Dermatol Online J Source Type: research

Eruptive nodules of the head and neck: a case report of metastatic prostate cancer.
Abstract Cutaneous metastasis is an uncommon but well recognized phenomenon occurring as a result of internal malignancy. Cancers most often associated with cutaneous metastasis are melanoma and primary malignancies of the breast and head and neck. Cutaneous metastatic prostate cancer is rare, representing only 1% of cases. Herein we report a case of advanced prostate cancer with multiple cutaneous metastases and briefly review the literature highlighting the clinical and histopathological features as well as a management approach to the patient with metastatic prostate cancer involving the skin. PMID: 246125...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Brown G, Kurtzman D, Lian F, Sligh J Tags: Dermatol Online J Source Type: research

Localized acne induced by radiation therapy.
We report two new cases of radiation-induced acne with different clinical aspects and discuss the main known features of this adverse event. PMID: 24612578 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Hubiche T, Sibaud V Tags: Dermatol Online J Source Type: research

Localized acneiform eruption following radiotherapy in a patient with breast carcinoma.
We present a case of a rare form of delayed radiation dermatitis consisting of a localized acneiform eruption, confirmed by skin biopsy, in the irradiated fields in a woman with breast cancer. We review the clinical characteristics and risk factors available in the literature about this unusual adverse effect of radiotherapy. It is important for dermatologists to recognize this rare adverse effect, owing to the important impact on physical and psychosocial health of the patients and because it may delay the surgical reconstruction. PMID: 24612579 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Turrion Merino L, Vano-Galvan S, Garcia de la Vega MU, Hermosa Zarza E, Garcia Del Real CM, Jaen Olasolo P Tags: Dermatol Online J Source Type: research

Transient symptomatic zinc deficiency in a preterm exclusively breast-fed infant.
Abstract A 5-month-old female infant, preterm, exclusively breast-fed, presented with a 2-month history of erythematous, erosive, and crusted patches and plaques in a peri-oral, scalp, genital, and peri-anal distribution. A clinical diagnosis of zinc deficiency was confirmed by a low serum zinc level in the infant and decreased maternal breast milk zinc. Complete resolution occurred within two weeks of oral zinc supplementation. Acquired zinc deficiency is a rare nutritional disorder of infants. Early diagnosis and adequate treatment will prevent associated morbidity and complications. PMID: 24612580 [PubMed ...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Laureano A, Bras S, Carvalho R, Amaro C, Cardoso J Tags: Dermatol Online J Source Type: research

Firm papules on the penis and scrotum.
Abstract An 18-year-old man presented with a 6-year history of penile and scrotal papules. Biopsy of one of the 1-3mm papules revealed calcinosis cutis. PMID: 24612581 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Holliday AC, Clos A, Kelly B Tags: Dermatol Online J Source Type: research

Angioedema-like allergic contact dermatitis related to black henna.
Abstract Allergic contact dermatitis related to para-phenylendiamine (PPD) from temporary black henna tattoos and hair dyes has become an epidemic in recent years. Several cases of adverse skin reactions to PPD have been reported in the literature. Herein, we present a case of angioedema-like allergic contact dermatitis related to hair coloring with henna. PMID: 24612582 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Gokalp H, Kaya K Tags: Dermatol Online J Source Type: research