A case report of adult-onset multiple angiokeratomas with zosteriform distribution.
We report an unusual case of multiple angiokeratomas in a zosteriform distribution with onset at age 74. PMID: 30677813 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Grewal AK, Chambers CJ, Silverstein M Tags: Dermatol Online J Source Type: research

Polycyclic annular presentation of pemphigus vulgaris with an eosinophil predominance in two pregnant patients.
P, Kılıç S Abstract Pemphigus during pregnancy has a more complicated course owing to the limitations in treatment options and alterations in the severity and presentation of the clinical features. We would like to present two pemphigus vulgaris (PV) cases associated with pregnancy with an unusual clinical appearance exhibiting polycyclic, annular, vesiculobullous plaques with marked eosinophil infiltration in histopathology. To the best of our knowledge pregnancy-associated pemphigus cases with this particular clinical presentation have not been reported in the literature. Changes in the immunologic and ...
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Küçükoğlu R, Sun GP, Kılıç S Tags: Dermatol Online J Source Type: research

A novel case of NKX3.1-positive metastatic cutaneous prostate cancer.
We present an 87-year-old man previously diagnosed with prostate cancer treated with brachytherapy, who presented with a metastatic prostate adenocarcinoma of the scalp mimicking a basal cell carcinoma. Herein, we present a patient with an NKX 3.1 positive cutaneous metastatic prostate carcinoma identified through NKX3.1 stain rather than the typical PSA/PSAP stain. PMID: 30677815 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Wong JK, Minni JP, Nowak MA Tags: Dermatol Online J Source Type: research

Basal cell carcinoma with intravascular invasion: A case report and review of the literature.
We report a case of an infiltrative BCC on the scalp that showed evidence of both intravascular and perineural invasion. The tumor locally recurred in the bone marrow space 4.5 years following the initial procedure. Since recurrence and metastasis of BCC can be delayed for many years, we recommend long term follow-up for tumors showing aggressive features. PMID: 30677816 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Mazloom S, Rich M, Grider D, Phillips M Tags: Dermatol Online J Source Type: research

Leukocytoclastic vasculitis with late-onset Henoch-Sch önlein purpura after trifluridine/tipiracil treatment.
We present a case of trifluridine/tipiracil-induced leukocytoclastic vasculitis (LCV) with late-onset Henoch-Schönlein purpura (HSP) in a 42-year-old man with metastatic appendiceal cancer. The patient's biopsy-proven LCV developed one month after he began trifluridine/tipiracil treatment and resolved after discontinuation of the drug. He presented to the emergency department two months after the appearance of his LCV with shortness of breath, elevated blood pressure, elevated creatinine, hematuria, and proteinuria. A kidney biopsy was performed and the presence of IgA deposits and cellular crescents indicated rapidly...
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Aria AB, Chen L, Glass WF, Lahoti A, Chon SY Tags: Dermatol Online J Source Type: research

Erythema annulare centrifugum-type eruption in a patient undergoing cancer vaccine immunotherapy.
We report a patient developing an immune related adverse effect from sipuleucel-T drug-induced erythema annulare centrifugum-like eruption. A brief review of the mechanism and implications of this eruption are also included. PMID: 30677818 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Tadros J, Rahnama-Moghadam S Tags: Dermatol Online J Source Type: research

Glomuvenous malformations in a young man.
Abstract A young man presented with blue nodules on the trunk, face, and extremities that gradually increased in number and size. His mother had similar lesions. Initially, blue rubber bleb nevus syndrome was suspected, but histological findings confirmed the diagnosis of hereditary glomuvenous malformations. Making the correct diagnosis spares the patient unnecessary evaluation for the arteriovenous malformations of the gastrointestinal tract associated with the former diagnosis. PMID: 30677819 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Abbas A, Braswell M, Bernieh A, Brodell RT Tags: Dermatol Online J Source Type: research

Eosinophilic pustular folliculitis with labial and oral involvement: report of a rare presentation.
Abstract Eosinophilic pustular folliculitis (EPF) is a recurrent inflammatory dermatosis primarily involving hair follicles. Several subtypes of EPF have been described: Classic EPF, infantile EPF, and immunosuppression-associated EPF. Although classic EPF has a predilection for face, involvement of hairless areas such as palms and soles has been reported frequently. There are rare case reports of mucosal EPF. Herein, we report a woman who presented with classic EPF involving the lip and oral mucosa. PMID: 30677820 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Sepaskhah M, Ahramian Pour N, Godarzi H, Sari Aslani F, Jowkar F Tags: Dermatol Online J Source Type: research

Acneiform eruption induced by vedolizumab.
We report a case of severe acneiform eruption induced by vedolizumab in a 17-year-old woman with ulcerative colitis. PMID: 30677821 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Magdaleno-Tapial J, Ferrer-Guillén B, Valenzuela-Oñate C, Esteve-Martínez A Tags: Dermatol Online J Source Type: research

Role of family history in patchy alopecia areata.
CONCLUSION: Patchy alopecia patients with a family history of alopecia areata experienced worse outcomes. Concomitant autoimmunity may also adversely affect alopecia areata disease course. Identification of a positive family history of alopecia areata and control of autoimmune comorbidities may aid alopecia areata management. PMID: 30677822 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Wang S, Ratnaparkhi R, Piliang M, Bergfeld WF Tags: Dermatol Online J Source Type: research

Augmenting the scope of dermatologic care and training via student-run health clinics.
Abstract Skin cancer is a major public health problem. Unfortunately, individuals who lack health insurance have lower skin cancer screening rates compared to insured individual and, therefore, have a higher risk of more advanced cancer diagnoses. Student-run health clinics may be the answer to this dilemma. Student-run health clinics can not only help by providing essential dermatologic services to the general population, both insured and uninsured, but also provide early exposure to dermatology education for medical students. PMID: 30677823 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 15, 2018 Category: Dermatology Authors: Kamath P, Stratman S, Agarwal N Tags: Dermatol Online J Source Type: research

Infantile hemangiomas: our current understanding and treatment options.
Abstract Infantile hemangioma (IH) is the most common vascular tumor of infancy, affecting up to 10% of all infants. Our understanding of IH and its management has greatly evolved. The etiology of IH is unclear but hypoxia is thought to play a key role. Furthermore, GLUT1, IGF2, and HIF-1-? are thought to be important mediators. Current management options include active observation, medical treatment, and surgical intervention. The goals of treatment are preventing cosmetic disfiguration, psychosocial distress, and life-threatening complications. Infantile hemangioma should be managed with an individual, patient-c...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Soliman YS, Khachemoune A Tags: Dermatol Online J Source Type: research

Psoriasis therapy and aortic inflammation - translating statistical to clinical significance.
Abstract Psoriasis patients are known to have comorbid aortic vascular inflammation, which is one of the leading causes of cardiovascular morbidity and mortality in this population. Many studies report statistically significant improvements in aortic vascular inflammation after use of tumor necrosis factor inhibitors or interleukin-12/23 antagonists. However, the clinical significance in reduction of adverse cardiovascular events in psoriatic patients owing to biologic therapy has not been examined. Regardless of clinically significant cardiovascular benefits, dermatologists should continue to treat psoriasis pati...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Kazemi A, Cline A, Cardwell LA, Feldman SR Tags: Dermatol Online J Source Type: research

Genital Rejuvenation: The Next Frontier in Medical and Cosmetic Dermatology.
Abstract Genital rejuvenation encompasses not only the nonsurgical interventions but also the surgical procedures that are utilized to improve the functional aspects and/or enhance the aesthetic presentation of the genitalia of women (vaginal rejuvenation) and men (scrotal rejuvenation). Vaginal rejuvenation was introduced into the medical literature in 2007; yet, within the last decade, physician and patient interest in this field has markedly increased. In contrast, the term scrotal rejuvenation was only coined in 2018. Rejuvenation of the genitalia may be considered for hair-associated (alopecia and hypertricho...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Cohen PR Tags: Dermatol Online J Source Type: research

Dermatologic features in good film characters who turn evil: the transformation.
Abstract Dermatologic depictions in film are often used to symbolize evil. To ascertain whether certain dermatologic characteristics are more representative of evil in movies, skin findings in film characters before and after evil transformation were compared using the Good Movie Characters Turned Bad poll courtesy of The Internet Movie Database (IMDb). The poll ranked the 35 most remarkable moral transformations in cinema. Data was analyzed from 27 characters who met study criteria and there was a statistically significant, greater number of dermatologic features seen in characters after an evil transformation. P...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Marion T, Reese V, Wagner RF Tags: Dermatol Online J Source Type: research

Tuberculosis and interleukin blocking monoclonal antibodies: Is there risk?
Abstract Several new monoclonal antibodies that interfere with interleukin (IL) cascades have come to market in recent years. They follow a generation of drugs that block tumor necrosis factor (TNF). It has been well established that TNF is important in the containment of Mycobacterium tuberculosis (Mtb) and that blocking this cytokine increases the risk of tuberculosis (TB) infection. Thus, judicious screening for Mtb of patients taking TNF blocking drugs has been the standard of care. It remains unclear if the newer monoclonal, interleukin blocking drugs, which affect IL-12, IL-23, and IL-17 pathways are associa...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Kelsey A, Chirch LM, Payette MJ Tags: Dermatol Online J Source Type: research

The use of notable protagonists in dermatology clinical cases: A quasi-randomized controlled trial.
CONCLUSIONS: The current study found that cases utilizing NPs, while still preserving the same educational value as cases using GPs, can provide a more entertaining learning experience and stimulate outside learning. PMID: 30677829 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Mayer JE, Garg A, Carson SH Tags: Dermatol Online J Source Type: research

The development of primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoproliferative disorder at the site of a melanoma excision scar.
We present the first case of PCSM-LPD, to our knowledge, arising at a past melanoma excision site. A 72-year-old woman with a past medical history significant for melanoma-in-situ excised 36 years ago presented to our clinic for evaluation of a single, erythematous plaque of the posterior arm within a melanoma excision scar. A biopsy was performed, revealing PCSM-LPD. Reports of the development of other T-cell lymphoproliferative disorders after prior skin trauma such as chemical burns, thermal injury, and mechanical trauma exist in the literature. Physicians should be aware of the possibility of the appearance of T-cell l...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Aria AB, Wilmas K, Kim EJ, Aung PP, Duvic M Tags: Dermatol Online J Source Type: research

Scabies presenting as cutaneous nodules or malar erythema: reports of patients with scabies surrepticius masquerading as prurigo nodularis or systemic lupus erythematosus.
In conclusion, Sarcoptes scabiei infestation can present with atypical clinical morphology and an absence of classical lesions such as burrows conventionally distributed in the interdigital web spaces, volar wrists, periumbilical area, or genitalia. Scabies surrepticius is a term that has been designated to describe these unusual presentations. Prurigo nodularis and systemic lupus erythematosus can be added to the litany of conditions masquerading as scabies and are included amongst the guises of scabies surrepticius. PMID: 30677831 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Werbel T, Hinds BR, Cohen PR Tags: Dermatol Online J Source Type: research

Subcutaneous panniculitis-like T-cell lymphoma responsive to combination therapy with methotrexate and corticosteroids.
Abstract Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare condition that falls underneath the umbrella of primary cutaneous T-cell lymphomas (CTCLs). SPTCL can be very difficult to diagnose as it may mimic other subtypes of CTCL, such as γ/δ T-cell lymphoma (TCL), or other forms of panniculitis. Confirmation of diagnosis often requires immunohistochemical analysis and is essential for proper prognosis and therapeutic management. Herein, we present a case of SPTCL that mimicked lupus panniculitis and was successfully treated with prednisone taper and methotrexate. PMID: 30677832 [Pu...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Grinich E, Koon SM, Cascio MJ, Fett N Tags: Dermatol Online J Source Type: research

Nodular amyloidosis in a patient with systemic scleroderma.
We report an unusual case of a patient with systemic scleroderma who developed primary cutaneous nodular amyloidosis on the left lower leg. The diagnosis was confirmed with a skin biopsy with Congo red staining and a novel technique using a laser microdissection and mass spectrometry-based proteomic analysis method for amyloid protein characterization. A work-up for systemic amyloidosis was negative and the patient improved symptomatically with wound care. Patients with primary cutaneous nodular amyloidosis should be followed clinically over time for the possible development of systemic amyloidosis, although the risk of di...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Marano AL, Selim MA, Cardones AR, Burton CS Tags: Dermatol Online J Source Type: research

A trichogenic tumor with aggressive features initially diagnosed as basal cell carcinoma.
We present a case in which a 73-year-old female had a long-standing scalp nodule for over 30 years that rapidly increased in size. The patient's lesion was initially diagnosed as basal cell carcinoma on shave biopsy, but upon excision, revealed features concerning for trichoblastic carcinoma such as brisk mitotic activity and comedo-like necrosis. Sudden change in an atypical scalp lesion that has been present for many years should increase suspicion for an atypical trichogenic tumor, such as trichoblastic carcinoma. PMID: 30677834 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Kwock JT, Casady M, Handfield C, MacLeod AS, Pavlis MB Tags: Dermatol Online J Source Type: research

Seven-year itch: a perplexing case of lichen planus-lupus erythematosus overlap syndrome.
We report a case of LP-LE overlap syndrome diagnosed in a man previously believed to have atypical lichen planus who presented with an exacerbation of exuberant pruritic erythematous scaly plaques. The patient had six separate skin biopsies all of which displayed features of LP. Because the clinical symptoms did not correlate to the histopathological picture, a seventh skin biopsy with direct immunofluorescence (DIF) was performed and immunologic markers measured. The DIF demonstrated early lupus bands; serologic testing exhibited elevated ANA and anti-SSA. These findings established the diagnosis of LP-LE overlap syndrome...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Schmitz S, Vatanchi M, Alapati U Tags: Dermatol Online J Source Type: research

Aplasia cutis cong énita con defecto óseo subyacente: evolución favorable tras manejo conservador.
Aplasia cutis congénita con defecto óseo subyacente: evolución favorable tras manejo conservador. Dermatol Online J. 2018 Sep 15;24(9): Authors: Higelmo-Gómez H, Míguez-Martín L, Barbato-Mateos JC, González-Martínez MT, Reimunde-Seoane ME, Rodríguez-Díaz E, Vázquez-Osorio I Abstract La aplasia cutis congénita es una rara alteración caracterizada por la ausencia de áreas localizadas de piel en el momento del nacimiento. Suele manifestarse como una lesión solitaria localizada principalmente en el cue...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Higelmo-Gómez H, Míguez-Martín L, Barbato-Mateos JC, González-Martínez MT, Reimunde-Seoane ME, Rodríguez-Díaz E, Vázquez-Osorio I Tags: Dermatol Online J Source Type: research

Secukinumab for psoriasis in a patient with hepatitis B.
Abstract The case reported describes a 48-year-old man with congenital hepatitis B receiving secukinumab for treatment of psoriasis. Some biologic therapies have been associated with an increased risk of reactivation of hepatitis B. In the case of this patient, secukinumab has successfully managed his psoriasis without evidence of hepatitis B virus reactivation. PMID: 30677838 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Feaster B, Cline A, Feldman SR Tags: Dermatol Online J Source Type: research

Effective treatment of nail psoriasis with apremilast: report of two cases and review of the literature.
We present two cases of patients who exhibited a rapid response to treatment with apremilast. PMID: 30677839 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Magdaleno-Tapial J, Valenzuela-Oñate C, Ortiz-Salvador JM, Subiabre-Ferrer D, Hernández-Bel P Tags: Dermatol Online J Source Type: research

The ginseng pimple: an inflammatory papule following ginseng consumption.
Abstract Ginseng is a popular herbal remedy derived from the plant roots of the Panax genus and has been used in traditional Asian medicine for thousands of years. In the United States, it has become increasingly popular and is taken for many conditions, including as an immune enhancer. Cutaneous adverse effects have been reported to occur following ginseng consumption, although detailed clinical descriptions are limited. A 60-year-old woman who repeatedly developed inflammatory papules following ginseng consumption is described and the characteristics of ginseng use in healthcare are reviewed. PMID: 30677840...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Chen SX, Cohen PR Tags: Dermatol Online J Source Type: research

Editorial boards of dermatology journals and their potential financial conflict of interest.
CONCLUSIONS: Financial relationships exist between editorial board members of dermatology journals and pharmaceutical/medical device manufacturing companies, which could lead to financial conflicts of interest. Publications coming from journals with highly paid physician editors have more potential to be biased. PMID: 30677841 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Updyke KM, Niu W, St Claire C, Schlager E, Knabel M, Leader NF, Sacotte RM, Dunnick CA, Dellavalle RP Tags: Dermatol Online J Source Type: research

RETRACTED: Ehlers-Danlos syndrome caused by the c.934C > T, p. Arg312Cys mutation in COL1A1 gene: an Italian family without cardiovascular events.
RETRACTED: Ehlers-Danlos syndrome caused by the c.934C>T, p. Arg312Cys mutation in COL1A1 gene: an Italian family without cardiovascular events. Dermatol Online J. 2018 Sep 15;24(9): Authors: Cortini F, Marinelli B, Seia M, Seresini A, Bassotti A Abstract The article entitled "Ehlers-Danlos syndrome caused by the c.934C>T, p. Arg312Cys mutation in COL1A1 gene: an Italian family without cardiovascular events" has been retracted because the description and characterization of the disease in a family may have been previously published. Upon publication of this article we were notified...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Cortini F, Marinelli B, Seia M, Seresini A, Bassotti A Tags: Dermatol Online J Source Type: research

Dermoscopy findings of a one mm lentigo maligna.
Abstract A 66-year-old man presented with a grayish 1mm macule on the left cheek. Dermatoscopic examination revealed annular-granular structures partially surrounding a single follicular ostium. Histopathologic examination demonstrated atypical, confluent single melanocytes at the basal layer with nesting, crowding, and upward migration descending along the hair follicle, consistent with the diagnosis of lentigo maligna (LM). This case presents evidence in support of the Schiffner progression model for LMs, starting with asymmetric pigmented follicular openings composed of annular-granular structures, which later ...
Source: Dermatol Online J - September 15, 2018 Category: Dermatology Authors: Witta S, Bershow A, Farah RS, Berg B, Goldfarb N Tags: Dermatol Online J Source Type: research

Reviewing the use of imiquimod for molluscum contagiosum.
Abstract We discuss imiquimod associated with non-application site mucosal reactions and two of our own clinical cases. In one of our patients, erosive cheilitis developed in a young boy after using topical imiquimod 5% cream for 5 nights weekly on bilateral cheeks, chin, and near vermillion border for molluscum contagiosum. The case is discussed with concerns for imiquimod use in molluscum contagiosum when used near mucosal surfaces. PMID: 30142710 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - August 23, 2018 Category: Dermatology Authors: DiBiagio JR, Pyle T, Green JJ Tags: Dermatol Online J Source Type: research

Epidermotropic cutaneous metastases of squamous cell carcinoma from primary esophageal cancer: report of a case and review of the literature.
We report the first case of epidermotropic cutaneous metastases of SCC originating from primary esophageal SCC with a review of the literature on this rare histological phenomenon. PMID: 30142711 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - August 23, 2018 Category: Dermatology Authors: Chang YC, Al-Haseni A, Bhawan J, Debjani S Tags: Dermatol Online J Source Type: research

Rapidly growing subcutaneous mass in an infant.
In this report we present a case of this rare entity, including the associated clinical, radiologic, and histologic findings. PMID: 30142742 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - July 26, 2018 Category: Dermatology Authors: Cardis MA, Huppmann AR, Kirkorian AY Tags: Dermatol Online J Source Type: research

Cannabinoids in dermatology: a scoping review.
Abstract The therapeutic applications of cannabis and cannabinoids are an increasingly conspicuous topic as de-criminalization and legalization of these products continues to expand. A limited number of cannabinoid compounds have been approved for a specific set of conditions. However, the current role of cannabinoids for the treatment of dermatologic conditions remains to be defined. We conducted a review of the current literature to determine the applications of cannabinoids for the therapy of various skin diseases. After conducting our analysis, we found that cannabinoid products have the potential to treat a v...
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Eagleston LRM, Kalani NK, Patel RR, Flaten HK, Dunnick CA, Dellavalle RP Tags: Dermatol Online J Source Type: research

Expediting patient appointments with dermatology rapid access clinics.
CONCLUSIONS: Dermatology rapid access clinics within an academic medical center can reduce wait times for higher acuity patients while maintaining patient satisfaction. PMID: 30142707 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Jayakumar KL, Samimi SS, Vittorio CC, Micheletti RG, Steele KT, Ogunleye TA, Richardson V, Chiesa ZC, Rosenbach M Tags: Dermatol Online J Source Type: research

Characteristics and diagnostic performance of pathologists who enjoy interpreting melanocytic lesions.
Abstract Diagnostic discrepancy among pathologists interpreting melanocytic skin lesions (MSL) is an ongoing concern for patient care. Given that job satisfaction could impact patient care, this study aimed to characterize which pathologists enjoy interpreting MSL and estimate the association between enjoyment and diagnostic accuracy. Pathologists' demographics, training, and experience were obtained by a cross-sectional survey. Associations between these characteristics and self-reported enjoyment when interpreting MSL were estimated by Pearson's Chi-square tests. Diagnostic accuracy was determined by comparing p...
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Radick AC, Phipps AI, Piepkorn MW, Nelson HD, Barnhill RL, Elder DE, Reisch LM, Frederick PD, Elmore JG Tags: Dermatol Online J Source Type: research

Addressing public criticism: a potential HIPAA violation.
We describe a case of a physician assistant revealing protected health information of a patient in response to a critical New York Times article. Providers must be wary of violating patients' privacy, even when they are criticized online. Addressing patients' concerns and neutral, caring online responses may be the physician's best options for responding to negative reviews. PMID: 30142709 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Martin E, Lober C, Benabio J, Feldman SR Tags: Dermatol Online J Source Type: research

Striking enhancement at the site of radiation for nivolumab-induced Stevens-Johnson syndrome.
We present a case of SJS in a patient being treated with anti-PD-1 therapy nivolumab for metastatic squamous cell carcinoma of the oropharynx. This case is unusual because of the severe accentuation with striking enhancement at his prior radiation site and in the cutaneous region with heavier tumor burden from his metastatic disease. This reaction may give insight to the underlying pathophysiology of SJS, suggesting that immune checkpoint inhibitors can activate T-cells to target keratinocytes and that external factors may be involved in creating distinct epitopes for T-cell recognition. We hope this case adds to the body ...
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Shah KM, Rancour EA, Al-Omari A, Rahnama-Moghadam S Tags: Dermatol Online J Source Type: research

Giant fibrous hamartoma of infancy: pitfall of CD34 positive dermal mesenchymal tumor.
This article highlights the importance of being aware of the CD34+ dermal mesenchymal tumor differential diagnosis and the necessity of appropriate size biopsies to avoid sampling error. PMID: 30142714 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Miroux-Catarino A, Claro C, Viana I Tags: Dermatol Online J Source Type: research

Estrogen receptor positive, progesterone receptor negative, leiomyoma of the areola of a male patient.
Abstract Leiomyoma of the nipple and areola is a rare subtype of genital leiomyoma. The etiology of the tumor is not well understood. However, sex hormones like estrogen and progesterone have been implicated in the tumorigenesis. Hereby, we report a 47-year-old man with an estrogen receptor positive, progesterone receptor negative, leiomyoma of the areola. PMID: 30142715 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Yuksel ME, Tamer F, Bozlak N Tags: Dermatol Online J Source Type: research

Atrophic dermatofibroma in an elderly male - a rarely described variant of a common lesion.
We describe a case of an atrophic dermatofibroma on the back of an elderly man. Skin biopsy demonstrated a spindle cell proliferation in a storiform pattern, loss of elastic fibers, and substantial atrophy of both the underlying dermis and subcutaneous tissue. An aggregation of elastic fibers was found in the periphery of the tumor. These histologic features supported the diagnosis of atrophic dermatofibroma. The dermal and adipocyte atrophy was likely responsible for the retracted appearance of the lesion. PMID: 30142716 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Morse DC, Tschen JA, Silapunt S Tags: Dermatol Online J Source Type: research

A survey study with assessment of esophageal screening and genetic counseling in patients with Howel-Evans syndrome.
CONCLUSIONS: We encourage dermatologists to discuss smoking-cessation, genetic counseling, and early EGD with affected families. PMID: 30142717 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Jenkins LE, Abner S, Schadt C Tags: Dermatol Online J Source Type: research

A recalcitrant case of Jacquet erosive diaper dermatitis after surgery for Hirschsprung disease in a boy with Waardenburg-Shah syndrome.
Abstract We herein present a 4 year-old boy with Waardenburg-Shah syndrome who developed Jacquet erosive diaper dermatitis following a total colectomy and ileoanal anastomosis procedure for Hirschsprung disease. The diagnosis was made according to history and typical clinical findings. Complete resolution of the recalcitrant lesions after an ileostomy procedure supported the diagnosis. This case highlights the importance of being familiar with the predisposing factors and clinical presentation of this rare and severe form of chronic irritant dermatitis, since it may easily be misdiagnosed as other diseases in chil...
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Babuna Kobaner G, Sun GP, Ozkaya E Tags: Dermatol Online J Source Type: research

Fixed drug eruption related to sunitinib: a case report.
Abstract Sunitinib is an oral multi-targeted tyrosine kinase inhibitor. It has been approved for the treatment of gastro-intestinal stromal tumor and advanced renal cell carcinoma. Fixed drug eruption related to sunitinib is a rare cutaneous adverse drug reaction. PMID: 30142719 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Bhatia A, Jha N, Kanish B Tags: Dermatol Online J Source Type: research

Cadaveric simulation for improving surgical training in dermatology.
Abstract Simulation models are rapidly changing medical education, especially the training of dermatology residents. Various models are available, including cadaveric simulations. Our study evaluates the impact of a cadaveric simulation on the training of dermatology residents. Over a period of three years, cadaveric simulation was shown to increase the surgical knowledge of residents. Residents were more confident in their knowledge of surgical anatomy and also surgical skills. Cadaveric simulation may offer a positive impact on resident training in dermatology. PMID: 30142720 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Hazan E, Torbeck R, Connolly D, Wang JV, Griffin T, Keller M, Trufant J Tags: Dermatol Online J Source Type: research

Eruptive melanocytic nevi in HIV infected patients: report of three cases.
We report three cases of eruptive nevi in men with human immunodeficiency virus type 1 infection. One patient developed this phenomenon during the stage of acquired immunodeficiency syndrome. The other two patients had human immunodeficiency virus infection recently diagnosed and presented to our clinic reporting the development of multiple melanocytic nevi after starting highly active antiretroviral treatment, with improvement of their immunity. To our knowledge, this is the first report of eruptive melanocytic nevi as a possible consequence of the immune reconstitution inflammatory syndrome. PMID: 30142721 [PubMed -...
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Garrido PM, Borges-Costa J Tags: Dermatol Online J Source Type: research

Addressing the average lifespan of skin diseases is critical to good patient care.
Abstract Dermatology patients routinely ask how long their skin condition may last, yet this critical aspect of their care has not been emphasized in the literature. When a given diagnosis may be self-limited, it is essential that clinicians meet patient expectations by properly discussing the possible time course for resolution. Furthermore, being aware of, and prioritizing the knowledge of the duration of a skin disease can help limit continued exposure to side effects of prescribed treatments once the condition may have self-resolved or remitted. PMID: 30142722 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Trivedi A, Pierson JC Tags: Dermatol Online J Source Type: research

Crusted scabies masquerading as psoriasis plaques in a patient suffering from burn scars.
Abstract A 30-year-old woman, presented with erythematous scaling plaques on her trunk with severe pruritus and a burning sensation that began 3 months prior to her visit. She had a history of a thermal burn in that area, three years prior. Topical corticosteroid application for 3 months had no positive effects. Skin biopsy was done and scabies mites were found. PMID: 30142723 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Dastgheib L, Boroujeni NH, Aslani FS Tags: Dermatol Online J Source Type: research

Subungual nail bed melanoma masquerading as tinea ungium.
In conclusion, in individuals with new morphologic changes to a dystrophic nail or with persistent nail dystrophy despite appropriate therapy, it is important for clinicians to consider performing additional evaluation and possible biopsy to exclude malignancy. PMID: 30142725 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Riahi RR, Cohen PR, Goldberg LH Tags: Dermatol Online J Source Type: research

Mycoplasma pneumoniae, more than a lung disease.
We report a case of MIRM in a previously healthy 15-year-old boy. PMID: 30142726 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - June 15, 2018 Category: Dermatology Authors: Curtiss P, Melnick L, Sicco KL, Liebman TN Tags: Dermatol Online J Source Type: research