Why sulfonamides are contraindicated in Rocky Mountain spotted fever.
Abstract Sulfonamide antibiotics are not effective for the treatment of Rocky Mountain spotted fever (RMSF). Patients suspected of having RMSF based on history and physical exam should be treated with doxycycline and not a sulfonamide to avoid increased morbidity and mortality. PMID: 24612569 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Ren V, Hsu S Tags: Dermatol Online J Source Type: research

Compliance with follow-up among patients with melanoma and non-melanoma skin cancers.
Conclusions: Patient compliance with physician recommended follow-up regimens is generally poor; further research and intervention is necessary to identify and address the underlying causes. PMID: 24612570 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Kalimullah FA, Brown CW Tags: Dermatol Online J Source Type: research

A slowly enlarging mass on the finger.
Abstract An otherwise healthy 71-year-old woman presented with an asymptomatic mass on her right 4th finger that had been slowly enlarging over the past 2 years. On physical examination, there was a tan-pink, freely mobile, rubbery 9-mm papule with a central keratotic plug located over the extensor aspect of the proximal interphalangeal joint of the right 4th finger. A 3-mm punch biopsy of the lesion was performed. Histopathologic findings were consistent with a diagnosis of aggressive digital papillary adenocarcinoma (ADPAca), an adnexal tumor with high metastatic potential that is unfortunately commonly misdiagn...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Jefferson J, Thompson C, Rich P Tags: Dermatol Online J Source Type: research

Erlotinib induced target-like purpura.
Abstract Erlotinib is an epidermal growth factor receptor (EGFR) inhibitor, used as a treatment for advanced stage cancer. The most common side effect is cutaneous toxicity including the already known papulopustular reaction. We herein report a case of erlotinib induced target-like purpura, a peculiar cutaneous adverse event. A 57-year-old patient with advanced non-small cell lung cancer was treated by erolotinib 150 mg daily. After taking the drug for three days, an unusual target-like purpura developed on her lower legs. Skin biopsy specimen taken from the lesion revealed an extravasation of erythrocytes in the ...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Rungtrakulchai R, Rerknimitr P Tags: Dermatol Online J Source Type: research

A case of harlequin ichthyosis treated with isotretinoin.
Abstract Harlequin ichthyosis is a rare congenital ichthyosis classified under the category of Autosomal Recessive Congenital Ichthyoses, which also include lamellar ichthyosis and congenital ichthyosiform erythroderma. It is caused by functional null mutations in the ABCA12 gene, a keratinocyte lipid transporter associated with lamellar granule formation. Patients have a classic clinical presentation at delivery and need neonatal intensive care treatment to maximize their chances of survival. Early oral retinoid therapy has been shown to increase survival in patients with harlequin ichthyosis[1], and we present a...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Chang LM, Reyes M Tags: Dermatol Online J Source Type: research

Cutaneous metastasis of a transitional cell carcinoma.
We describe a rare case of a urolethial carcinoma metastatic to the skin in an elderly female. The metastasis expanded rapidly and was thought to possibly be infectious on her initial evaluation by her primary team. We were called in as consultants and biopsied this mass to confirm our concern for metastatic disease. In this case there was an unknown primary tumor. Histologic staining patterns were used to suggest that the tumor may have originated from her urinary bladder. PMID: 24612574 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Schmiedecke R, Perry A, Satter EK Tags: Dermatol Online J Source Type: research

Oral compound nevus.
Abstract The melanocytic nevus is a benign and focal proliferation of nevus cells that can be congenital or acquired. Intraoral lesions are uncommon, and the etiology and pathogenesis are poorly understood. The occurrence rate of oral compound nevus is about 5.9% to 16.5% of all oral melanocytic nevi. A 22-year-old male patient presented with a dark brown macule on the buccal mucosa of the maxilla in the region of tooth 26. The lesion was elliptical, 0.7 x 0.5 cm, well circumscribed, asymptomatic, and the evolution time was unknown. An excisional biopsy was performed and microscopic analysis revealed nests of nevu...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Cardoso LB, Consalaro A, Da Silva Santos PS, Da Silva Sampieri MB, Tinoco-Araujo JE Tags: Dermatol Online J Source Type: research

Dermoscopy in Merkel cell carcinoma: a case report.
We report the case of an 82-year old woman with a Merkel cell carcinoma on the face. Clinical and histopathological features are presented. In addition, dermoscopic features and the differential diagnosis of this rare tumor are discussed. Although nodules with atypical dermoscopic vascular pattern and milky-red areas will end up being excised, this report adds more clues to the rarely described dermoscopic morphologic presentation of MCC. PMID: 24612576 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Laureano A, Cunha D, Pernandes C, Cardoso J Tags: Dermatol Online J Source Type: research

Eruptive nodules of the head and neck: a case report of metastatic prostate cancer.
Abstract Cutaneous metastasis is an uncommon but well recognized phenomenon occurring as a result of internal malignancy. Cancers most often associated with cutaneous metastasis are melanoma and primary malignancies of the breast and head and neck. Cutaneous metastatic prostate cancer is rare, representing only 1% of cases. Herein we report a case of advanced prostate cancer with multiple cutaneous metastases and briefly review the literature highlighting the clinical and histopathological features as well as a management approach to the patient with metastatic prostate cancer involving the skin. PMID: 246125...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Brown G, Kurtzman D, Lian F, Sligh J Tags: Dermatol Online J Source Type: research

Localized acne induced by radiation therapy.
We report two new cases of radiation-induced acne with different clinical aspects and discuss the main known features of this adverse event. PMID: 24612578 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Hubiche T, Sibaud V Tags: Dermatol Online J Source Type: research

Localized acneiform eruption following radiotherapy in a patient with breast carcinoma.
We present a case of a rare form of delayed radiation dermatitis consisting of a localized acneiform eruption, confirmed by skin biopsy, in the irradiated fields in a woman with breast cancer. We review the clinical characteristics and risk factors available in the literature about this unusual adverse effect of radiotherapy. It is important for dermatologists to recognize this rare adverse effect, owing to the important impact on physical and psychosocial health of the patients and because it may delay the surgical reconstruction. PMID: 24612579 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Turrion Merino L, Vano-Galvan S, Garcia de la Vega MU, Hermosa Zarza E, Garcia Del Real CM, Jaen Olasolo P Tags: Dermatol Online J Source Type: research

Transient symptomatic zinc deficiency in a preterm exclusively breast-fed infant.
Abstract A 5-month-old female infant, preterm, exclusively breast-fed, presented with a 2-month history of erythematous, erosive, and crusted patches and plaques in a peri-oral, scalp, genital, and peri-anal distribution. A clinical diagnosis of zinc deficiency was confirmed by a low serum zinc level in the infant and decreased maternal breast milk zinc. Complete resolution occurred within two weeks of oral zinc supplementation. Acquired zinc deficiency is a rare nutritional disorder of infants. Early diagnosis and adequate treatment will prevent associated morbidity and complications. PMID: 24612580 [PubMed ...
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Laureano A, Bras S, Carvalho R, Amaro C, Cardoso J Tags: Dermatol Online J Source Type: research

Firm papules on the penis and scrotum.
Abstract An 18-year-old man presented with a 6-year history of penile and scrotal papules. Biopsy of one of the 1-3mm papules revealed calcinosis cutis. PMID: 24612581 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Holliday AC, Clos A, Kelly B Tags: Dermatol Online J Source Type: research

Angioedema-like allergic contact dermatitis related to black henna.
Abstract Allergic contact dermatitis related to para-phenylendiamine (PPD) from temporary black henna tattoos and hair dyes has become an epidemic in recent years. Several cases of adverse skin reactions to PPD have been reported in the literature. Herein, we present a case of angioedema-like allergic contact dermatitis related to hair coloring with henna. PMID: 24612582 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Gokalp H, Kaya K Tags: Dermatol Online J Source Type: research

Fibromatosis digital infantil de presentación atípica.
We present a case of infantile digital fibromatosis in a 6-years-old child. PMID: 24612583 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Bernat Garcia J, Fuertes Prosper A, Marti Ibor E, Marquina Vila A Tags: Dermatol Online J Source Type: research

Changing pigmentation in a solitary scalp lesion.
Abstract A healthy 66 year-old man presented with a complaint of changes within a nodule on the scalp, which had first appeared over 10 years prior. He had no previous history of skin cancer. On physical examination a solitary, asymmetric, purple-black nodule with irregular borders was identified on the right vertex of his scalp. The remainder of his examination did not reveal any additional lesions. PMID: 24612584 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - March 18, 2014 Category: Dermatology Authors: Oros ML, Elenitsas R, Chu EY Tags: Dermatol Online J Source Type: research

Anakinra-responsive lichen planus in a woman with Erdheim-Chester disease: a therapeutic enigma.
Conclusions: Our experience confirms the efficacy of anakinra for the treatment of Erdheim-Chester disease. The concomitant improvement of her lichen planus on anakinra suggests that this agent warrants additional study in this disorder. PMID: 24456945 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Cohen PR, Kurzrock R Tags: Dermatol Online J Source Type: research

Imatinib-induced postoperative periorbital purpura: GASP (Gleevec-Associated Surgical Purpura) in a woman with imatinib-treated chronic myelogenous leukemia.
Conclusion: We recommend discontinuing imatinib usage one week prior to periorbital surgery and not resuming therapy until the eighth postoperative day. PMID: 24456946 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Anzalone CL, Cohen PR, Kurzrock R, Cortes JE Tags: Dermatol Online J Source Type: research

Increasing recognition of dermatomyositis with subcutaneous edema - is this a poorer prognostic marker?
We report a case involving a 38-year-old man who presented with significant subcutaneous edema involving his neck and upper body; he later developed clinical features and biopsy results consistent with dermatomyositis. Only sixteen previous cases of dermatomyositis with subcutaneous edema involving adults have been published in the literature and we aim to review disease progression, prognosis, and optimal treatment of the condition. PMID: 24456947 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Tu J, McLean-Tooke A, Junckerstorff R Tags: Dermatol Online J Source Type: research

Alpha-1-antitrypsin deficiency-associated panniculitis: a case report.
We report the case of a 55-year old woman with A1AT panniculitis associated with the heterozygous phenotype PiMS and discrete reduction of A1AT serum levels. In addition, the pathophysiology of the disease, clinical and histopathological features, and current treatment possibilities are briefly reviewed. PMID: 24456948 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Laureano A, Carvalho R, Chaveiro A, Cardoso J Tags: Dermatol Online J Source Type: research

Eruptive purpuric papules on the arms; a case of chemotherapy-induced inflammation of actinic keratoses and review of the literature.
We report a case of a 67-year-old man with a history of chronic hepatitis B virus infection and recently diagnosed squamous cell carcinoma of the lung who was noted to have progressive asymptomatic violaceous papules on the extensor forearms and distal upper arms while hospitalized for possible sepsis following initiation of chemotherapy. A dermatology consulatation was requested to rule out possible vasculitis. It is important to recognize chemotherapy-induced inflammation of actinic keratoses in predisposed patients; it may be managed successfully with topical corticosteroids and does not necessitate discontinuation of t...
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Chambers CJ, Liu H, White CR, White KP, Sharon VR Tags: Dermatol Online J Source Type: research

Primary amyloidosis-induced nail dystrophy.
Abstract Primary amyloidosis is caused by a monoclonal proliferation of plasma cells and is capable of producing cutaneous lesions. A 56-year-old male was admitted to the hospital for evaluation of chronic back pain and acute lower extremity weakness. On examination, he was noted to have subungual verrucous plaques with overlying nail dystrophy on his bilateral thumbs. A biopsy of one subungual lesion showed a deposition of amorphous material in the dermis that stained with Congo red and crystal violet. These cutaneous lesions ultimately led to the diagnosis of plasma cell dyscrasia and primary amyloidosis. Based ...
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Tausend W, Neill M, Kelly B Tags: Dermatol Online J Source Type: research

Systematized linear epidermolytic hyperkeratosis.
Abstract A 5-year-old boy presented with widespread asymptomatic hyperpigmented verrucous plaques since 3 months of age. The lesions were distributed in a linear manner along Blaschko's lines on trunk and extremities and were accentuated in flexures and around joints. There was no history of blistering or redness and no other family member was affected. Ichthyosis hystrix (of Curth and Macklin) and generalized linear/mosaic epidermolytic hyperkeratosis (EHK) were considered in the differential diagnosis. Biopsy from both trunk lesion and lesion on knee revealed characteristic epidermolytic hyperkeratosis, thereby ...
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Kumar P, Kumar R, Mandal RK, Hassan S Tags: Dermatol Online J Source Type: research

Acute onset of a vesiculopustular rash in an ICU patient.
Abstract A 63 year-old woman with hyperthyroidism was admitted to the Medical Intensive Care Unit for ARDS following damage to her lungs from propylthiouracil. She was placed on 250 mg SSKI PO TID as an alternative therapy until thyroidectomy could be performed. Four days after admission, she abruptly developed an acneiform rash on her face, shown to be iododerma. The eruption rapidly resolved after discontinuation of the SSKI. PMID: 24456952 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Frankel AJ, Ahmad M, Perl M, Yao J, Pereira F Tags: Dermatol Online J Source Type: research

Treatment of subcutaneous sarcoidosis with hydroxychloroquine: Report of 2 cases.
We describe the cases of two patients with subcutaneous sarcoidosis treated with hydroxychloroquine, suggesting that it may represent an alternative first-line treatment for patients in whom steroid-sparing therapy is desired. PMID: 24456953 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Marchetti M, Baker MG, Noland MM Tags: Dermatol Online J Source Type: research

Congenital malalignment of the great toenail. Report of two cases.
We report two cases of congenital malalignment of the great toenail in two otherwise healthy children. Because this entity is probably underdiagnosed, a high index of suspicion is required to prevent from diagnostic errors and unnecessary treatments. PMID: 24456954 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Batalla A, Curto JR Tags: Dermatol Online J Source Type: research

Traumatic neuroma of the penis.
We describe a case of traumatic neuroma on the penis of a 24-year-old man; the tumor was initially suspected to be a condyloma. A shave biopsy was both diagnostic and curative. PMID: 24456955 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Hoverson KR, Sasaki GT, Wohltmann WE Tags: Dermatol Online J Source Type: research

Verruciform xanthoma.
Abstract A 50-year-old man presented with a several month history of a polypoid papule on the scrotum. A dense accumulation of macrophages with foamy cytoplasm was exhibited in the biopsy specimen leading to a diagnosis of verruciform xanthoma. PMID: 24456956 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Gill BJ, Chan AJ, Hsu S Tags: Dermatol Online J Source Type: research

Getting to the point: a case of a sewing needle retrieved from the thigh.
Abstract Foreign bodies are rarely retained in the skin after puncture wounds or impalement injuries and are even less commonly initially detected several months after penetration. Sewing needles are most frequently reported in the literature as foreign bodies in cases of ingestion, inoculation of the cranium and heart, and penetration of the knee. Herein we describe a case of a middle-aged man who presented to the outpatient dermatology clinic with an 8-month history of a nodule in his left thigh; he had noted recent onset of mild pain. On examination he was found to have a sharp needle-like point palpable below ...
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Brezinski EA, Eisen DB, Burrall B Tags: Dermatol Online J Source Type: research

An unusual erysipelas-like presentation.
Abstract A 61-year-old man presented with erysipelas-like cutaneous leishmaniasis. PMID: 24456958 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Siah TW, Lavender T, Charlton F, Wahie S, Schwab U Tags: Dermatol Online J Source Type: research

A case of eosinophilic dermatosis of hematologic malignancy in a patient with multiple myeloma.
Abstract A 50-year-old man with eosinophilic dermatosis of hematologic malignancy is presented. His dermatosis cleared after chemotherapy produced improved control of his multiple myeloma. PMID: 24456959 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Two AM, Li C, Hata T Tags: Dermatol Online J Source Type: research

A simplified minimally invasive technique for the treatment of venous lakes.
Abstract A simplified approach to treat venous lakes of the vermillion lip is presented. Our method involves the use of a 30 gauge hypodermic needle to deliver a low-powered, high-frequency electrical current from a hyfrecator power source into the venous lake lesion. PMID: 24456960 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Weiss J, Weiss KD, Ross AL, Weiss E Tags: Dermatol Online J Source Type: research

Generalized morphea successfully treated with extracorporeal photochemotherapy (ECP).
Abstract A patient is presented with generalized morphea whose disease completely resolved after combination therapy with extracorporeal photopheresis and broad band UVA treatments. PMID: 24456961 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Pileri A, Raone B, Raboni R, Giudice V, Patrizi A Tags: Dermatol Online J Source Type: research

Herpes zoster in a 2-year-old vaccinated against varicella.
We report a case of herpes zoster in a 2-year-old boy who received the live attenuated varicella zoster virus vaccination at his 12-month pediatric visit. The child was treated with acyclovir and recovered without complications. PMID: 24456962 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Ulman CA, Trevino JJ, Gandhi RK Tags: Dermatol Online J Source Type: research

Fish odor syndrome: a case report of trimethylaminuria.
We report a case of trimethylaminuria in a 12-year-old girl. The patient failed treatment with diet and hygiene modification, but achieved symptomatic improvement after a four-month course of metronidazole. PMID: 24456963 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Ulman CA, Trevino JJ, Miller M, Gandhi RK Tags: Dermatol Online J Source Type: research

Chemical burn caused by topical application of garlic under occlusion.
We report an unusually severe case of chemical burn following garlic applied under occlusion. PMID: 24456964 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - February 3, 2014 Category: Dermatology Authors: Xu S, Heller M, Wu PA, Nambudiri VE Tags: Dermatol Online J Source Type: research

Livedo reticularis.
We report an additional case of a patient with both LR and CNKL and suggest a possible mechanism that explains this association. PMID: 24364996 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Rose AE, Sagger V, Boyd KP, Patel RR, McLellan B Tags: Dermatol Online J Source Type: research

Spiny keratoderma.
We present a case of a 48-year-old man with an approximately 30-year history of spiny projections on the palms, which were histopathologically consistent with spiny keratoderma. Spiny keratoderma is a rare entity of unknown etiology that has been described with both hereditary and acquired variants. The hereditary form, which is most likely the diagnosis in our patient, manifests at a younger age and is benign. The acquired variant, which presents in older adults, has been associated with a variety of systemic diseases and malignant conditions. In patients suspected of having acquired spiny keratoderma, an evaluation for m...
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Nagler A, Boyd KP, Patel RR, Lee HS Tags: Dermatol Online J Source Type: research

Verrucous epidermal nevus.
Abstract A 64-year-old man presented with a three-year history of an enlarging, pruritic, linear, verrucous plaque on his left lower extremity. Histopathologic examination was consistent with a verrucous epidermal nevus, which is a benign epidermal hamartoma, most commonly observed in the pediatric population. Verrucous epidermal nevi are often refractory to treatment and have high rates of recurrences, causing them to be therapeutic challenges. We review the treatment modalities reported to be effective in verrucous epidermal nevi. PMID: 24364998 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Kim R, Marmon S, Kaplan J, Kamino H, Pomeranz MK Tags: Dermatol Online J Source Type: research

Granulomatous dermatitis related to silicone implant.
We present a case of a woman with clinical and serologic findings that are consistent with systemic lupus erythematosus and a histopathologic diagnosis of foreign body granulomatous dermatitis 20 years after solid silicone nasal implantation. We review the literature on silicone granulomas and their treatment and speculate on the potential etiologies of a challenging case presentation. PMID: 24364999 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Rieder E, Desai S, Mundi JP, Boyd KP, Patel RR, Ramachandran S, Franks AG Tags: Dermatol Online J Source Type: research

Necrolytic acral erythema.
Abstract Necrolytic acral erythema is a rare, cutaneous manifestation of hepatitis C virus infection that is characterized by erythematous, violaceous or dusky papules, blisters, and/or erosions in the early stages and by well-demarcated, hyperkeratotic, targetoid plaques with a peripheral rim of macular erythema, secondary lichenification and hyperpigmentation, and overlying fine micaceous or necrotic-appearing scale in the later stages. Because most topical modalities prove ineffective, treatment of the underlying viral infection or therapeutic zinc supplementation are required for clinical improvement. PMI...
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Yost JM, Boyd KP, Patel RR, Ramachandran S, Franks AG Tags: Dermatol Online J Source Type: research

Graft-vs-host disease.
We present a case of chronic graft-versus-host disease in a 61-year-old woman with a history of B-cell chronic lymphocytic leukemia that was treated with an allogeneic bone marrow transplant from an unrelated donor. The patient initially presented with erythematous patches on the trunk and extremities that evolved into reticulated, hyperpigmented patches and lichenified plaques. PMID: 24365001 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Tran K, Kaplan J, Kamino H, Latkowski JA Tags: Dermatol Online J Source Type: research

Primary localized cutaneous amyloidosis.
Abstract A 61-year-old man presented for evaluation of a bruise-like lesion of the right knee. He was found to have an ill-defined, light brown patch with focal areas of dark red and brown. The histopathologic diagnosis was consistent with amyloidosis. Further subtyping showed that the amyloid protein was AL (κ). A systemic evaluation failed to show internal involvement. Amyloidosis comprises a spectrum of diseases, which range from systemic to localized cutaneous types, and is characterized by the extracellular deposition of amyloidosis protein as beta-pleated sheets. The forms of amyloidosis are differenti...
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Terushkin V, Boyd KP, Patel RR, McLellan B Tags: Dermatol Online J Source Type: research

Fluoroscopy-associated radiation dermatitis.
We present a 67-year-old man with an ulcerated, indurated plaque on the right mid back with a presumed diagnosis of morphea that was complicated by an allergic contact dermatitis. Further clinical and histopathologic data elucidated the diagnosis of fluoroscopy-induced radiation dermatitis. We present a brief review of the common locations, clinical characteristics, pathophysiology, and management options for fluoroscopy-induced radiation dermatitis. PMID: 24365003 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Mundi JP, Kanchanapoomi M, Boyd KP, Patel RR, Kamino H, Cohen DE Tags: Dermatol Online J Source Type: research

Lichen planus pigmentosus.
We present a unique case of LPP that was characterized by an atypical initial inflammatory phase and subsequent circinate lesions with central clearing. PMID: 24365004 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Rieder E, Kaplan J, Kamino H, Sanchez M, Pomeranz MK Tags: Dermatol Online J Source Type: research

Lichen sclerosus et atrophicus.
We present a case of a patient with lesions characterized by overlapping features of morphea and LSA with rapid decrease in joint mobility. PMID: 24365005 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Rose AE, Boyd KP, Meehan SA, Latkowski JA Tags: Dermatol Online J Source Type: research

Pemphigoid gestationis.
We present a 21-year-old primigravida woman with a several-week history of pruritic, edematous, targetoid plaques that appeared initially on the abdomen, flanks, and legs and that progressed to involve the inner aspects of the upper arms and lateral aspects of the chest. The histopathologic findings showed perivascular and interstitial dermatitis with eosinophils and vacuolar changes with linear C3 deposition at the basement-membrane zone on direct immunofluorescence study. A diagnosis of pemphigoid gestationis was made. Pemphigoid gestationis is a rare, bullous dermatosis of pregnancy that may be associated with prematuri...
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Stevenson ML, Marmon S, Tsou H, Boyd KP, Robinson MR, Meehan SA, Pomerantz R Tags: Dermatol Online J Source Type: research

Flagellate erythema.
Abstract A 21-year-old woman presented with a pruritic eruption on her trunk and extremities after receiving bleomycin for treatment of stage III ovarian germ-cell tumor. Physical examination was consistent with bleomycin-induced flagellate erythema. We discuss the pathophysiologic mechanism that produces this dermatitis. PMID: 24365007 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Eungdamrong J, McLellan B Tags: Dermatol Online J Source Type: research

Hemifacial atrophy.
We report the case of a 44-year-old woman with a one-year history of en coup de sabre morphea and progressive hemifacial atrophy with ipsilateral hemifacial neuralgia, migraine, and contralateral neurologic abnormalities. While rare, Parry-Romberg syndrome typically presents in the first or second decade of life; this patient's case is unusual in that the onset of her disease is demonstrated at age 43. Common clinical features, laboratory findings, and pathogenetic theories are discussed. PMID: 24365008 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Vedvyas C, Urbanek RW Tags: Dermatol Online J Source Type: research

Scleredema diabeticorum.
We present a case of scleredema with a leonine facies in a 56-year-old man with a history of poorly controlled diabetes mellitus. The patient initially presented with erythematous, edematous papules and plaques on the face, neck, and upper back. PMID: 24365009 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 27, 2013 Category: Dermatology Authors: Tran K, Boyd KP, Robinson MR, Whitlow M Tags: Dermatol Online J Source Type: research