Oral manifestations of connective tissue disease and novel therapeutic approaches.
Abstract Connective tissue diseases such as systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and Sjögren syndrome (SS) have presented many difficulties both in their diagnosis and treatment. Known causes for this difficulty include uncertainty of disease etiology, the multitude of clinical presentations, the unpredictable disease course, and the variable cell types, soluble mediators, and tissue factors that are believed to play a role in the pathogenesis of connective tissue diseases. The characteristic oral findings seen with these specific connective tissue diseases may assist with more swift ...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Heath KR, Rogers RS, Fazel N Tags: Dermatol Online J Source Type: research

Lichen planus pigmentosus in linear and zosteriform pattern along the lines of Blaschko.
Abstract Lichen planus pigmentosus (LPP) is a variant of lichen planus (LP) reported in various ethnic groups. It occurs predominantly in the third or fourth decade of life and is characterized by the insidious onset of dark-brown macules in sun exposed areas and flexural folds. Rarely, has it been described in a linear or segmental distribution. Herein we describe a case of LPP with lesions lateralized to right side of body along the lines of Blaschko, in a linear and zosteriform pattern. PMID: 26632802 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Vineet R, Sumit S, K GV, Nita K Tags: Dermatol Online J Source Type: research

Novel mutation in the fumarate hydratase gene in a patient with Reed syndrome.
We present a 40-year-old woman with history of large uterine leiomyomas who presented with a two-year history of a pruritic papular eruption on the left neck refractory to topical corticosteroids. After histopathologic examination and genetic work-up, the patient was found to have a novel mutation in the fumarate hydratase gene and was subsequently diagnosed with Reed syndrome. PMID: 26632803 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Smith S, Casady M, Driscoll MS Tags: Dermatol Online J Source Type: research

Equestrian perniosis: A case report and review of the literature.
Abstract Equestrian perniosis is a rare form of perniosis that is predominantly seen in young female equestrians who ride in cold temperatures. Tight fitting clothing, age under 35 years, and smoking can contribute to the disease manifestation. The diagnosis can be determined from a thorough history and physical examination. However, a biopsy can be taken to confirm the diagnosis. Although many cases are self-limiting and resolve within a few days to weeks of diagnosis, nifedipinie can be considered as a therapeutic measure for persistent cases. Measures such as wearing loose fitting clothing and horseback riding ...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Dane A, Rama S, Sikorski L Tags: Dermatol Online J Source Type: research

[In Process Citation].
Abstract Pachonychia congenita is an uncommon genodermatosis, classified among the disorders of keratinization and caused by mutation of certain keratin genes.  The characteristic clinical triad is onychodystrophy, keratoderma, and plantar pain.  In addition, the patients may present with epidermal cysts, steatocystomas, leukokeratosis, and deciduous teeth. PMID: 26632805 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Cuestas Sde A, Puchades AM, Vila AM Tags: Dermatol Online J Source Type: research

Juvenile dermatomyositis with joint contractures and calcinosis cutis.
Abstract A 12-year-old boy presented to our department with firm papules on the fingers of both hands, erythematous scaly plaques on the dorsum of the hands and elbow, and deformities and limitation of motion in the joints of the hands and feet. His parents reported that the eruption started 6 years prior to presentation. He was previously diagnosed with psoriasis by physicians and acitretin treatment was given. However, he did not benefit from the treatment. PMID: 26632806 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Turan E, Yesilova Y, Surucu HA, Tanrikulu O, Eroglu N, Kocarslan S Tags: Dermatol Online J Source Type: research

LEOPARD Syndrome.
In this report we would like to highlight the importance of detailed clinical examination and appropriate imaging in patients with multiple lentigines. PMID: 26632807 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Ghosh SK, Majumdar B, Rudra O, Chakraborty S Tags: Dermatol Online J Source Type: research

Increasing medical student exposure to clinical dermatology through participation in volunteer clinics.
We report our experience of increasing medical student exposure to clinical dermatology thorough involvement in an extracurricular, volunteer-driven dermatology clinic. The clinic was well received by students and faculty. Our experience demonstrates that volunteer-driven dermatology clinics may be an effective method of teaching and engendering a culture of community outreach among medical students and faculty. PMID: 26632808 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Beroukhim K, Nguyen C, Danesh M, Lee K, Liao W Tags: Dermatol Online J Source Type: research

What are the most important factors that determine the overall quality of dermatology residency training: A resident survey.
Abstract Currently no broadly accepted and standardized objective ranking system for dermatology residency programs exist. A new ranking system was recently developed in an attempt to address this issue. However, it remains unclear if the algorithm employed is based on factors that have a tangible impact on the quality of training provided by dermatology residency programs [1]. Our authors surveyed all current dermatology residents in order to investigate the factors that they feel are most important in determining the strength of training provided by a residency program. PMID: 26632809 [PubMed - in process] ...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Guffey D, Feldman SR, Huang WW Tags: Dermatol Online J Source Type: research

Subungual hematoma: clinical appearance of resolution over time.
We report a case of subungual hemorrhage in diabetes. PMID: 26632810 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Chieb S, Baha H, Hali F Tags: Dermatol Online J Source Type: research

Terra firma-forme dermatosis: Case Series and dermoscopic features.
In conclusion dermoscopy can assist in the evaluation of terra firma-forme dermatosis and the dermoscopic evaluation of other dirty dermatoses is recommended in the future to compare findings with TFFD. PMID: 26632811 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Abdel-Razek MM, Fathy H Tags: Dermatol Online J Source Type: research

The use of botanical products and vitamins in sunscreens.
Abstract The use of botanical products and vitamins in skin care creams and sunscreens is prevalent. Herein we conduct an evaluation of sunscreens to quantitatively assess how often sunscreens incorporate botanically derived products and vitamins. The most commonly used botanicals products and vitamins are identified and stratified based on the sunscreen sun protection factor (SPF). The overall prevalence for the use of botanical agents and vitamins was 62% and 79%, respectively. Aloe vera and licorice root extracts were the most common botanical agents used in sunscreens. Retinyl palmitate was the most common vit...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Monico G, Leo M, Ma B, Johal RS, Ma T, Sivamani RK Tags: Dermatol Online J Source Type: research

Skin simulators for dermatological procedures.
CONCLUSION: Efficient, realistic skin simulators are readily available for practice, which should enhance the safety of the practitioner and improve outcomes of novices. PMID: 26632926 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Wang X, Albahrani Y, Pan M, Levitt J Tags: Dermatol Online J Source Type: research

Usefulness of a "puzzle" flap; more than an advancement flap for surgical reconstruction of nasal ala defects: Review of 10 cases.
Usefulness of a "puzzle" flap; more than an advancement flap for surgical reconstruction of nasal ala defects: Review of 10 cases. Dermatol Online J. 2015;21(11) Authors: Padilla Espana L, Fernandez-Canedo I, De Troya Martin M Abstract Reconstructive surgery in nasal pyramid can be a challenge for surgeons. Moreover this anatomic area is one the most common sites for non-melanoma skin cancer. The "puzzle" flap was described to repair surgical defects located just on the nasal ala affecting melolabial sulcus. We have seen this flap can be also very useful to repair defects located o...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Padilla Espana L, Fernandez-Canedo I, De Troya Martin M Tags: Dermatol Online J Source Type: research

Treatment of metastatic cutaneous Crohn disease with certolizumab.
We report a case of a 32-year-old woman with history of Crohn disease who was admitted for treatment of cellulitis after presenting with a tender erythematous plaque of the left calf. Microbiological tests including tissue cultures were negative. A skin biopsy revealed granulomatous dermatitis consistent with metastatic cutaneous Crohn disease. Owing to concomitant perianal fistulas and abscesses and prior infusion reaction to infliximab, the patient was treated with certolizumab, a pegylated tumor necrosis factor (TNF) inhibitor combined with methotrexate resulting in complete resolution of the skin lesion. This case emph...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Kiuru M, Camp B, Adhami K, Jacob V, Magro C, Wildman H Tags: Dermatol Online J Source Type: research

Unilateral nevoid trichoepitheliomas on the neck: an unfamiliar presentation.
We report herein an adolescent male patient with multiple trichoepitheliomas, linearly arranged and dermatomal, present since birth, along the left side of the neck. PMID: 26632929 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Das A, Podder I, Bandyopadhyay D, Bhattacharya S Tags: Dermatol Online J Source Type: research

Adalimumab-induced psoriatic alopecia/alopecia areata-like reaction in a patient with Crohn's disease.
We report a case of alopecia associated with psoriasiform skin lesions in a patient on adalimumab treatment for Crohn's disease. PMID: 26632930 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Toda-Brito H, Lopes L, Soares-Almeida L, Filipe P Tags: Dermatol Online J Source Type: research

Persistent blaschkitis responsive to high potency topical steroids.
Abstract Blaschkitis is an acquired, rare dermatosis distributed along the lines of Blaschko. The papulovesicular eruption generally resolves in weeks and shows minimal response to topical steroids. Herein, we present a case of blaschkitis in an adult male who had lesions present for one year, which showed significant improvement after two weeks of topical clobetasol ointment. PMID: 26632931 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Liddell LT, Matinpour K, Mir M, McCain C, Diwan AH Tags: Dermatol Online J Source Type: research

Hyperkeratotic variant of porokeratosis in a patient with Hepatitis C virus infection and a concomitant immunosuppressed state.
Abstract Porokeratoses are acquired and hereditary disorders of keratinization that share a distinctive lesion characterized by raised keratotic borders corresponding histologically to an angled column of parakeratotic cells, called a cornoid lamella. Although a precise mechanistic explanation is lacking, ultraviolet radiation and immunosuppressed states are considered causally-associated with most cases of acquired porokeratosis. Hepatitis C virus (HCV) infection has been proposed as a link between the immunosuppressed states and development of acquired porokeratosis. Among the various recognized clinical entitie...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Parekh V, Kabihting FD, Junkins-Hopkins JM Tags: Dermatol Online J Source Type: research

A curious case of blue-green discoloration in a middle-aged indian man: Chromhidrosis.
CONCLUSION: Our case emphasizes the importance of considering any type of ingested medicine, including homeopathic medicine, as a probable cause of chromhidrosis. PMID: 26632933 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Ghosh SK, Rudra O, Kar R, Ghosh A, Agarwal M Tags: Dermatol Online J Source Type: research

Pressure-induced isomorphic sclerodermoid graft-versus-host disease from brassiere underwire and tight-fitting watch.
Abstract Sclerodermoid chronic graft-versus-host disease (scGVHD) is a rare form of cGVHD with an estimated prevalence of 3% to 11% in patients receiving allogeneic bone marrow transplants. scGVHD is believed to be an immune-mediated response characterized by aberrant T-cell function and dysregulation of tyrosine kinase cascades. Published literature on scGVHD is still limited and the mechanisms are yet to be fully understood. Thus, successful treatment of scGVHD remains largely unknown and many current options are hindered by potential side effects. This case provides an example of scGVHD localizing to areas of t...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Nielson C, Fraga GR, Fischer R, Rajpara A Tags: Dermatol Online J Source Type: research

Folliculocentric cutaneous presentation of disseminated Candida krusei infection in a patient with acute myeloid leukemia.
We present a unique case to contribute to the growing knowledge base associated with this organism. During hospitalization for neutropenic fever, a 19-year-old man with acute myeloid leukemia, who underwent hematopoietic stem cell transplantation, developed a generalized folliculocentric eruption following initiation of antifungal therapy for newly diagnosed C. krusei fungemia. Despite adequate antifungal coverage and negative blood cultures, the follicular-based erythematous papules persisted. Biopsies demonstrated yeast within ruptured follicles, without angiotropism or involvement of the interfollicular dermis, subcutan...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Qi J, Jourabchi N, Balagula Y, Sheu M, Fischer MK Tags: Dermatol Online J Source Type: research

Ungual squamous cell carcinoma mimicking a chronic paronychia: clinical, pathological and radiological correlation.
We report the case of a 73-year-old woman with a locally invasive squamous cell carcinoma reaching the bone, simulating a chronic paronychia. PMID: 26632936 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Lobato-Berezo A, Fernandez-Valencia-Kettunen CK, Burgos-Lazaro F, Martinez-Perez M, Aguilar-Martinez A, Gallego-Valdes MA Tags: Dermatol Online J Source Type: research

Painful nodule in the caesarean section scar of a young woman.
Abstract Endometriosis is the presence of ectopic endometrial tissue outside the uterus and cutaneous endometriosis is a rare manifestation of this disease that may be found at the sites of surgical scars as a result of iatrogenic implantation. Herein we present a case of scar endometriosis in a 35-year-old woman. The scar was sustained following a remote caesarean section. PMID: 26632937 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Russo VA, Alikhan A Tags: Dermatol Online J Source Type: research

Impact of the Pregnancy and Lactation Labeling Rule (PLLR) on Practicing Dermatologists.
Abstract On June 30th 2015, the FDA instituted a new system for the categorization of drug safety during pregnancy and lactation, known as the Pregnancy and Lactation Labeling Rule (PLLR), which replaces the "A, B, C, D, X" pregnancy labeling categories. The new rule will apply to all newly approved prescription medications, with a staggered phase-in for prescription drugs approved prior to the effective date. In this article, we provide a brief description of the major changes introduced by the PLLR and discuss the major implication of this new categorization system for clinical dermatologists. PMI...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Beroukhim K, Abrouk M, Farahnik B Tags: Dermatol Online J Source Type: research

Extensive keloid formation after pemphigus vulgaris.
We describe a case of a 67- year-old man with pemphigus vulgaris who suffered severe keloidal scarring after the pemphigus lesions became infected. His keloids were treated with intralesional corticosteroids with some improvement. Pemphigus vulgaris, a process confined to the epidermis, may lead to scarring in predisposed individuals, particularly if infection occurs. PMID: 26632939 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Sako EY, Workwick S Tags: Dermatol Online J Source Type: research

Paronychia-like cutaneous leishmaniasis.
We report one patient with paronychia  revealing ungueal leishmaniasis. A 34-year-old man, resident in the north of Morocco, presented with a 6-month history of an inflamed proximal nail fold of  the left thumb, resistant to antibiotics and anti-fungal treatments. En bloc excision of the proximal nail fold was done. The histopathological exam showed epithelioid  granulomas  with giant  cells and the presence of  leshmania  amastigotes, leading to the diagnosis of ungueal leishmaniasis. Clinical aspects of cutaneous leishmaniasis can be very misleading. The paronychial form is rarely descr...
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Chiheb S, El Machbouh L, Marnissi F Tags: Dermatol Online J Source Type: research

Failure of lichen planopilaris to respond to ustekinumab.
Abstract Lichen planopilaris failed to respond to ustekinumab after 10 months of treatment. PMID: 26632941 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Webster G Tags: Dermatol Online J Source Type: research

Professional dermatology societies in the USA: an overview.
Abstract This is a concise overview in a table format for the current membership-based dermatology societies in the USA. The primary objective of these societies is to provide continuous medical education. These societies serve all health care providers in dermatology care, including physician assistants and nurses. There is a clear need for establishing more societies which focus on different aspect of dermatology. There is always a potential for improving the educational activities of these societies. PMID: 26632942 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Al Aboud A, Al Aboud K Tags: Dermatol Online J Source Type: research

Cutaneous myiasis of scalp in a young girl related to Musca domestica.
Abstract Cutaneous myiasis is a parasitic disease secondary to the presence of the larvae of certain insects, particularly diptera, in the skin of man or vertebrates [1]. Human myiasis is a rare clinical condition, but more frequently seen in tropical and subtropical areas. Hot humid climate with inadequate sanitary conditions favor the development of this condition.  Dermatitis, psychiatric illnesses, leprosy, and diabetes are some contributory factors [2]. Treatment of myiasis, once diagnosed, is simple and rapid recovery is anticipated. PMID: 26632943 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Rahman A, Ishfaq A, Arshad Azmi M, Khatoon N Tags: Dermatol Online J Source Type: research

Dermatologic health literacy in underserved communities: a case report of south Los Angeles middle schools.
CONCLUSIONS: Our hypothesis in this dermatologic health literacy study was that before necessary education, the required fund of knowledge with respect to skin cancer risk is lacking in several ethnic communities, but that intended compliance occurs when educational intervention occurs.  The data, both quantitative and qualitative, demonstrate that our hypothesis is substantiated. PMID: 26632944 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 5, 2015 Category: Dermatology Authors: Chapman LW, Ochoa A, Tenconi F, Herman A Tags: Dermatol Online J Source Type: research

Psoriasis disease severity affects patient satisfaction with treatment.
CONCLUSION: Many psoriasis patients were dissatisfied with their treatment; moderate-to-severe patients expressed significantly less satisfaction than mild patients. PMID: 26436965 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Korman NJ, Zhao Y, Lu J, Tran MH Tags: Dermatol Online J Source Type: research

Beta blocker treatment for infantile hemangiomas.
Abstract Infantile hemangiomas (IH) are common childhood vascular tumors.  Treatment of IH has undergone rapid change in recent years.  Since 2008, oral propranolol has been used to treat complicated IH and has proven superior to previously used therapies.  More recently, the efficacy of other systemic beta blockers, specifically atenolol and nadolol, has been reported.  In addition, topical timolol solution has been effective for treatment of smaller, more superficial IH.  The purpose of this article is to review the current literature of beta-blocker therapy for IH. PMID: 26436966 [...
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Rouhana HF, Fruge JH, Massengale WT Tags: Dermatol Online J Source Type: research

Successful treatment of psoriasis with ustekinumab in patients with multiple sclerosis.
Abstract Psoriasis is a chronic inflammatory disease, evolving from a complex interplay of genetic and environmental factors. In the recent years, we have seen much progress in understanding the immunopathogenesis of psoriasis, paving the way for new therapies with biologics. Currently, the most commonly used biologics in psoriasis are TNF inhibitors etanercept, infliximab and adalimumab, and the IL-12/23 inhibitor ustekinumab. As TNF inhibitors are contraindicated in patients with multiple sclerosis, ustekinumab remained the only biologic available for these patient before the recent approval of Secukinumab, an I...
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Chang S, Chambers CJ, Liu FT, Armstrong AW Tags: Dermatol Online J Source Type: research

Acquired cutis laxa associated with cutaneous mastocytosis.
This report describes a 26-year old woman who developed acquired cutis laxa and cutaneous mastocytosis leading to premature aging. She represents a unique co-occurrence of these two separate disease entities. To our knowledge, there has been only one published case report of acquired cutis laxa occurring in association with urticaria pigmentosa in a 4-year old girl. Our case would be a second case that exhibits the coexistence of these two disorders in an adult female. PMID: 26436968 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Hoang MV, Dang PV, Bui DV, Mejbel H, Mani DT, Smoller BR, Phung TL Tags: Dermatol Online J Source Type: research

Alopecia as the Presenting Symptom of Syphilis.
In this report, we present a case of a patient with essential syphilitic alopecia whose sole presenting symptom of syphilis was alopecia. Despite an initial negative rapid plasma reagin (RPR) test, he was ultimately found to have syphilis on scalp biopsy. His alopecia improved following treatment with benzathine penicillin. This presentation serves as a reminder to clinicians to be cognizant of alopecia as a presenting sign of syphilis. A review of the specificity and sensitivity of the typical tests used for the diagnosis is presented. PMID: 26436969 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Ornelas J, Agbai ON, Kiuru M, Sivamani RK Tags: Dermatol Online J Source Type: research

Elevated levels of antibodies against phosphatidylserine/prothrombin complex and/or cardiolipin associated with infection and recurrent purpura in a child: a forme fruste of antiphospholipid syndrome?
We report a case we describe as forme fruste antiphospholipid syndrome in which these criteria were not fulfilled. Purpura appeared repeatedly in a female infant starting from the age of 6 months and following episodes of upper respiratory infections and vaccinations. The levels of anti-cardiolipin IgG antibodies and anti-phosphatidylserine/prothrombin complex antibodies were elevated in accordance with these events. Histopathological evaluation revealed multiple small vessel thrombi in the dermis and adipose tissue. After 2 weeks of treatment with aspirin and heparin, the cutaneous symptoms subsided. Infection has long be...
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Kinoshita Y, Mayumi N, Inaba M, Igarashi T, Katagiri I, Kawana S Tags: Dermatol Online J Source Type: research

A case of hair re-pigmentation from a scalp melanoma.
We describe a 58-year-old woman who developed hair re-pigmentation on her vertex scalp as a marker of underlying melanoma. Histopathology revealed a nodular melanoma that was surrounding but not invading follicular epithelium. To our knowledge, there have only been 4 other previously published cases describing hair re-pigmentation in the setting of scalp melanoma. Focal hair re-pigmentation in adults should prompt a thorough evaluation for an underlying melanoma. PMID: 26436971 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Oza VS, Schulman JM, Mully TW, Ortiz S Tags: Dermatol Online J Source Type: research

Linear acral pseudolymphomatous angiokeratoma of children with associated nail dystrophy.
We describe a case of linearly-oriented infiltrative papules and nodules on the index finger of a young female with associated onychodystrophy. Histology demonstrated a heavy lymphocytic infiltrate with plasma cells and proliferation of blood vessels consistent with APACHE. Our case is unique given the linear array of cutaneous lesions and associated nail dystrophy. PMID: 26436972 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: McFaddin C, Greene J, Parekh P Tags: Dermatol Online J Source Type: research

"Cyrano nose" associated with hepatic hemangiomas successfully treated with propranolol.
We describe a patient who presented at two months of age with a "Cyrano nose" associated with multiple hepatic and cutaneous hemangiomas, which completely resolved after therapy with propranolol. Treatment was well tolerated and aesthetic result was excellent. PMID: 26436973 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Vergine G, Sorci M, Rosafio C, Bigucci B, Filippini B, Ancora G Tags: Dermatol Online J Source Type: research

Blue rubber bleb nevus syndrome: a rare multisystem affliction.
Abstract About 200 cases of blue rubber bleb nevus syndrome (BRBNS) have been reported in the literature. The disorder affects both sexes equally and the occurrence is mostly sporadic except for a few reports of cases with autosomal dominant inheritance pattern. Herein we report an 11-year-old girl with progressive BRBNS and onset at 5 years of age. PMID: 26436974 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Sangwan A, Kaur S, Jain VK, Dayal S Tags: Dermatol Online J Source Type: research

A case of acanthosis nigricans coexisting with mycosis fungoides.
We report a 67-year-old man that presented clinically with acanthosis nigricans, in which a subsequent diagnosis of mycosis fungoides was made. PMID: 26436975 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Cheng E, Roy DB, Magro CM Tags: Dermatol Online J Source Type: research

Síndrome de Graham-Little-Piccardi-Lassueur: variante disseminada de líquen plano folicular.
Síndrome de Graham-Little-Piccardi-Lassueur: variante disseminada de líquen plano folicular. Dermatol Online J. 2015;21(7) Authors: Kakizaki P, Donati A, Valente NY, Romiti R Abstract Graham-Little-Piccardi-Lassueur syndrome is a rare lichenoid dermatosis. It is characterized by the triad of scarring alopecia of the scalp, alopecia of the axilla and or groin, and keratotic follicular papules of the body. The present paper reports on two cases affecting young women. Histopathological findings suggest the disorder represents a generalized form of lichen planus follicularis. PMID: 2643...
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Kakizaki P, Donati A, Valente NY, Romiti R Tags: Dermatol Online J Source Type: research

Histiocytoid Sweet syndrome treated with azathioprine: a case report.
We report a 22-year-old woman with HSS, who, after minimal improvement with colchicine and dapsone, had significant improvement of her cutaneous eruption and systemic symptoms following empiric treatment with azathioprine. Since azathioprine has historically been known to cause SS, this case highlights a previously unreported treatment response for the histiocytoid variant. PMID: 26436977 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Miller J, Lee N, Sami N Tags: Dermatol Online J Source Type: research

A fibrous papule with abundant CD34-immunoreactive ganglion-like multinucleated giant cells: a case report and review of the literature.
Abstract Fibrous papules present clinically as benign, asymptomatic, dome-shaped, flesh colored papules on the face. Histologically, fibrous papules are characterized by fibrous stroma with fibroblasts and dilated blood vessels. Multiple variants of fibrous papules have been reported. Although scattered multinucleated cells in fibrous papules have been well described, we report a fibrous papule with abundant multinucleated ganglion-like giant cells that were immunoreactive with CD34. Recognition of such fibrous papule variants is important to avoid misdiagnosis as potentially more worrisome and/or aggressive melan...
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Schaberg KB, Chiou AS, Wang KC, Egbert BM Tags: Dermatol Online J Source Type: research

Jejunal adenocarcinoma with cutaneous metastasis.
We present a 60-year old man who developed a cutaneous metastasis of jejunal adenocarcinoma to his neck. This case highlights the clinicopathologic and immunophenotypic features of this uncommon cutaneous metastasis. PMID: 26436979 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Chung E, Syklawer E, Pulitzer MP, Marchetti MA, Querfeld C, Myskowski PL Tags: Dermatol Online J Source Type: research

Unilateral hyperkeratotic plaques along blaschko lines.
Abstract Epidermolytic ichthyosis (or epidermolytic hyperkeratosis) classically presents with erythroderma and increased fragility (blistering) at birth or soon thereafter. In later life, erythroderma and blistering improve gradually and the clinical picture is dominated by hyperkeratotic plaques in flexures and around joints. Linear epidermolytic hyperkeratosis is a unique, uncommon clinical variant and the absence of erythroderma and blistering are its hallmark. Linear lesions may be localized or generalized andunilateral or bilateral. Herein we report a 6-year-old girl with unilateral epidermolytic ichthyosis. ...
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Kumar P, Debbarman P, Rk S Tags: Dermatol Online J Source Type: research

Pitiríase rotunda: uma apresentação incomum.
Pitiríase rotunda: uma apresentação incomum. Dermatol Online J. 2015;21(7) Authors: Villa Verde RB, Viana Barbosa L, De Almeida Issa MC, Pantaleao L, Pavlikoff Issa L, Barbosa Luz F Abstract Pityriasis rotunda disorder of keratinization clinically described as persistent, large, sharply defined circular patches of ichthyosiform scaling with no inflammatory changes. Patients with pityriasis rotunda may be classified into one of two groups, which are based on ethnicity, number of lesions, family history, and association with systemic diseases. A 45-year-old woman presented with asym...
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Villa Verde RB, Viana Barbosa L, De Almeida Issa MC, Pantaleao L, Pavlikoff Issa L, Barbosa Luz F Tags: Dermatol Online J Source Type: research

Early diagnosis of subungual squamous cell carcinoma of the hallux.
We present a case of subungual SCC of the first toe without bone invasion. The tumor was diagnosed early, treated with conservative surgical excision, and showed no recurrence or metastasis after 2 years of follow-up. PMID: 26436982 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Kaksi SA, Ozdemir M, Balevi A, Cakir A, Tavh Y Tags: Dermatol Online J Source Type: research

Dermatology consultations in a tertiary care hospital: A retrospective study of 243 cases.
CONCLUSIONS: Our results revealed that common dermatoses account for a majority of dermatologic consultations. Modern ward teams continue to struggle with promptly recognizing and appropriately managing common skin conditions. Further training of ward physicians on common dermatologic conditions will improve recognition and treatment of skin conditions in hospitalized patients. PMID: 26437155 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - October 9, 2015 Category: Dermatology Authors: Connolly DM, Silverstein DI Tags: Dermatol Online J Source Type: research