Editorial: precision medicine of sarcomas and aggressive connective tissue tumours: from one-size-fits-all to haute couture
No abstract available (Source: Current Opinion in Oncology)
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SARCOMAS: Edited by Jean-Yves Blay Source Type: research

Content features and its implementation in novel app-based psycho-oncological interventions for cancer survivors: a narrative review
Purpose of review The interest in and availability of app-based psycho-oncological interventions for cancer survivors has grown rapidly. In this narrative review, we therefore aim to provide an overview of the psychological content features included in psycho-oncological apps and how the content is implemented in the apps. Recent findings A total of 19 studies (six randomized controlled trials, six studies with prepost design, five study protocols and two app developments), all published in the last 18 months (July 2020 to December 2021), were analyzed in terms of the described app-based interventions and their ...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Dyadic psychosocial interventions for patients with cancer and their caregivers: an update
Purpose of review Cancer causes significant impacts on patients and their caregivers. Cancer is also associated with multiple physical and emotional challenges for the patient-caregiver dyad. This patient-caregiver dyad should be considered as a unit of care by healthcare providers and supported through dedicated psychological interventions. Recent findings Twelve studies that tested dyadic interventions aiming to support patient-caregiver dyads were identified from the period April 2020 to December 2021. Studies were predominantly randomized controlled trials (RCTs) and single-arm pilot studies. Half of the int...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Interventions for children of parents with cancer: an overview
Purpose of review The purpose of this overview is to analyze existing reviews on psychosocial interventions for children of parents with cancer and synthesize implications for further practice, interventions, and research in this field. The aim of this overview is therefore to generate systematic knowledge about what can be classed as evidence-based knowledge in this field. Recent findings The literature search in MEDLINE, CINAHL, PsycINFO, PSYNDEX, and PsycARTICLES resulted in three systematic reviews, which were evaluated by the AMSTAR-2-tool for quality assessment and the PRISMA-checklist for reporting. Resul...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

How to support parenting in patients with cancer and co-parents? From research to practice
Purpose of review When a parent is diagnosed with cancer, the entire family is impacted. Patients with cancer and co-parents may no longer feel able to fulfill their parenting roles. The aims of this article are to describe interventions designed to support parenting in the oncological context and to make suggestions for the development and assessment of such interventions. Recent findings Ten parenting support interventions published in the last 10 years in oncology were identified, among which four randomized controlled trials (RCTs). The therapeutic aims, techniques, and modalities of these interventions we...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Interventions addressing fear of cancer recurrence: challenges and future perspectives
Purpose of review Fear of cancer recurrence (FCR) is a common concern among cancer survivors and support for FCR is one of the most cited unmet needs. High FCR was found to be related to increased use of healthcare services, specifically primary healthcare and medical consultations, and lower quality of life. In the past decade screening instruments for FCR and interventions have been developed and proven effective. Recent findings Systematic reviews and meta-analyses have shown that psychological treatments are effective for reducing FCR. The cost-effectiveness of FCR interventions could be increased by conside...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Psycho-oncology interventions focusing on fatigue and sleep disturbances
Purpose of review Cancer-related fatigue (CRF) and sleep disturbances are common symptoms among patients with cancer. They are often conceptualized as a part of a larger symptom cluster, also comprising pain and emotional distress. Despite their prevalence and long-lasting effects, CRF and sleep disturbances are still poorly addressed in clinical settings. Specific interventions are needed to manage these symptoms. Recent findings In addition to conventional pharmacological therapies, other kinds of interventions are increasingly being developed in oncology. This review will discuss three categories of intervent...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Question prompt lists to improve communication between cancer patients and healthcare professionals
Purpose of review This literature review sets out to summarize knowledge on the impact of question prompt lists (QPLs) on patient-physician communication in oncology and to provide an account of current research on the development, adaptation, and implementation of this type of communication tool. Recent findings Provided with a QPL, patients seem to ask more questions, in particular on sensitive issues like those around the end-of-life period and they recall the information provided better. There is a need to adapt QPLs, taking account of divergences in attitudes towards illness, participation in decision-makin...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Psychological interventions targeting patients with metastatic cancer and prolonged survival expectancies: advances and challenges
Purpose of review The purpose of this article is to review the formats and techniques of psychological interventions designed for patients with metastatic cancer and prolonged survival expectancies. Recent findings Fifteen interventional studies were selected for this article. One group of psychological interventions focused primarily on patients’ adaptation by increasing their knowledge, developing patients’ stress management skills, promoting their open communication with healthcare providers, and helping them deal with existential concerns. Another group of interventions focused on patients with moderate ...
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Editorial: Psychological interventions in oncology: advances and challenges
No abstract available (Source: Current Opinion in Oncology)
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: SUPPORTIVE CARE: Edited by Jean A. Klastersky and Yves Libert Source Type: research

Editorial introductions
No abstract available (Source: Current Opinion in Oncology)
Source: Current Opinion in Oncology - July 1, 2022 Category: Cancer & Oncology Tags: EDITORIAL INTRODUCTIONS Source Type: research

Renal oncocytoma: a challenging diagnosis
Purpose of review The aim of the review is to provide an update on the current and evolving approaches to diagnosing the challenging clinical entity of renal oncocytoma. Recent findings Renal oncocytoma is being increasingly recognized among patients with renal masses, and it can be found in up to 50% of benign small renal masses (SRMs) less than 4 cm. Renal oncocytomas have benign clinical biology but distinguishing them from some of the other renal masses with more malignant potential can be challenging due to overlapping imaging, histologic, and immunophenotypic characteristics. Increasing integration of va...
Source: Current Opinion in Oncology - May 1, 2022 Category: Cancer & Oncology Tags: GENITOURINARY SYSTEM: Edited by Arif Hussain Source Type: research

The roaring 2020s: a new decade of systemic therapy for renal cell carcinoma
Purpose of review The genomic and immunologic profiling of renal cell carcinoma (RCC) has provided the impetus for advancements in systemic treatments using combination therapy – either with immune check point inhibitor (ICI) + ICI or with ICI + targeted therapy. This approach has been examined in several landmark trials, treating both clear cell (ccRCC) and nonclear cell (nccRCC) histologies. In this review, we highlight systemic therapy advancements made in this new decade, the 2020s. Recent findings Targeting the programmed death receptor 1/PD-L1 pathway has created more tolerable and effective immu...
Source: Current Opinion in Oncology - May 1, 2022 Category: Cancer & Oncology Tags: GENITOURINARY SYSTEM: Edited by Arif Hussain Source Type: research

Recent advances in the treatment of advanced prostate cancer: maximizing existing therapies while searching for novel solutions
Purpose of review Present highlights from recent research examining treatment of advanced prostate cancer. Recent findings Data are emerging that combining androgen deprivation, docetaxel, and additional androgen-receptor-targeted therapies in treatment naïve metastatic prostate cancer may be an effective strategy to improve outcomes. Genomically targeted therapies and radiopharmaceuticals continue to be evaluated in the treatment of advanced castration-resistant prostate cancer. Summary Although no clear consensus has emerged regarding the best sequencing of available therapeutics, trial results continu...
Source: Current Opinion in Oncology - May 1, 2022 Category: Cancer & Oncology Tags: GENITOURINARY SYSTEM: Edited by Arif Hussain Source Type: research

Active surveillance in favorable intermediate risk prostate cancer: outstanding questions and controversies
This article serves to review relevant data, particularly the safety of active surveillance in grade group 2 patients, and what tools are available to aid in selecting a favorable subset of intermediate risk patients. Recent findings Active surveillance studies with long-term data appear to report worsened survival outcomes in intermediate risk patients when compared to those undergoing definitive treatment, but there exists a subset of intermediate risk patients with nearly equivalent outcomes to low risk patients on active surveillance. Tools such as percentage and total length of Gleason pattern 4, tumor volume, ...
Source: Current Opinion in Oncology - May 1, 2022 Category: Cancer & Oncology Tags: GENITOURINARY SYSTEM: Edited by Arif Hussain Source Type: research