The Impact of Dairy Intake on Adiposity and Satiety in Adults
AbstractPurpose of ReviewThe 2020 Dietary Guidelines for Americans (DGA) recommends that American adults consume 2 to 3 daily servings of dairy foods as part of healthy dietary patterns. The DGA ’s recommended dietary patterns are intended to meet nutrient needs and reduce the risk of chronic diseases, including overweight and obesity. However, the evidence reviews that the 2020 DGA is based on, the 2020 Dietary Guidelines Scientific Advisory Report, did not assess the body of evidence li nking individual foods to adiposity. The purpose of this review is to assess the evidence published in the last 10 years on dairy cons...
Source: Current Cardiovascular Risk Reports - June 20, 2021 Category: Cardiology Source Type: research

Feasibility of Incorporating Voice Technology and Virtual Assistants in Cardiovascular Care and Clinical Trials
AbstractPurpose of ReviewWith the rising cost of cardiovascular clinical trials, there is interest in determining whether new technologies can increase cost effectiveness. This review focuses on current and potential uses of voice-based technologies, including virtual assistants, in cardiovascular clinical trials.Recent FindingsNumerous potential uses for voice-based technologies have begun to emerge within cardiovascular medicine. Voice biomarkers, subtle changes in speech parameters, have emerged as a potential tool to diagnose and monitor many cardiovascular conditions, including heart failure, coronary artery disease, ...
Source: Current Cardiovascular Risk Reports - June 20, 2021 Category: Cardiology Source Type: research

My Approach to Sudden Death Risk Evaluation in Athletes, Who Should Play and Who Can Return to Play?
AbstractPurpose of ReviewAlthough the absolute risk of sudden death in the athlete is low, pre-articipation evaluation is an important opportunity to assess risk as well as establish a working relationship with the patient. In this chapter, we review the basis for our approach to pre-participation evaluation of an athlete.Recent FindingsTo date, no randomized study has compared the additive benefit of the screening ECG; however, the false positive rate is now in an acceptably low range. Different imaging modalities and/or exercise stress testing may provide important adjunctive information.SummaryThoughtful assessment of t...
Source: Current Cardiovascular Risk Reports - June 9, 2021 Category: Cardiology Source Type: research

Novel Digital Technologies for Blood Pressure Monitoring and Hypertension Management
AbstractPurpose of ReviewHypertension is common, impacting an estimated 108 million US adults, and deadly, responsible for the deaths of one in six adults annually. Optimal management includes frequent blood pressure monitoring and antihypertensive medication titration, but in the traditional office-based care delivery model, patients have their blood pressure measured only intermittently and in a way that is subject to misdiagnosis with white coat or masked hypertension. There is a growing opportunity to leverage our expanding repository of digital technology to reimagine hypertension care delivery. This paper reviews exi...
Source: Current Cardiovascular Risk Reports - June 9, 2021 Category: Cardiology Source Type: research

Unintentional Weight Loss as a Marker of Malignancy Across Body Weight Categories
AbstractPurpose of ReviewWeight loss has long been known to be associated with multiple chronic conditions, including heart failure, COPD, depression, and cancer. Recent reports have suggested that unintentional weight loss (UWL) could be leveraged as an early marker of malignancy. Most studies use standardized cutoff values of ≥5% weight loss to define UWL; however, this threshold has not been validated in different body weight classifications (underweight, overweight, etc.). The purpose of this review was to describe the association between a patient’s weight category, the severity of UWL prior to cancer diagnosis, c...
Source: Current Cardiovascular Risk Reports - June 3, 2021 Category: Cardiology Source Type: research

Risk Factor Management in Atrial Fibrillation: How to Deliver a Successful Clinic
AbstractPurpose of ReviewTo summarize the evidence underpinning the role of risk factor management in atrial fibrillation (AF) and to describe the key components critical to the successful delivery of this aspect of AF care.Recent FindingsRecent studies exploring the role of risk factor management in AF have demonstrated the importance of comprehensively and simultaneously managing all risk factors. Strong evidence exists to support the aggressive management of overweight and obesity, hypertension, diabetes, obstructive sleep apnea, alcohol excess, and physical inactivity in improving outcomes in this population. Other fac...
Source: Current Cardiovascular Risk Reports - May 27, 2021 Category: Cardiology Source Type: research

Racial and Ethnic Disparities in Transthyretin Cardiac Amyloidosis
AbstractPurpose of ReviewTransthyretin amyloid cardiomyopathy (ATTR-CM) is a life-threatening disease that disproportionately affects older adults and people of African descent. This review discusses current knowledge regarding racial and ethnic disparities in the diagnosis and management of ATTR-CM.Recent FindingsHistorically, ATTR-CM was thought to be a rare cause of heart failure. Recent evidence has shown that ATTR-CM is more common among older adults, men, and people of African descent. In addition, significant geographic variation exists in the identification of amyloid cardiomyopathy. Despite the high burden of ATTR...
Source: Current Cardiovascular Risk Reports - April 4, 2021 Category: Cardiology Source Type: research

Arrhythmogenic Cardiomyopathy: Mechanisms, Genetics, and Their Clinical Implications
AbstractPurpose of ReviewArrhythmogenic cardiomyopathy (ACM) represents a collection of cardiomyopathies with etiologies convergent upon highly arrhythmogenic clinical presentations not explained by ischemic, hypertensive, or valvular heart disease. This review describes the current state of knowledge regarding molecular mechanisms and genetic diagnosis in ACM.Recent FindingsClinical manifestations, specifically structural presentations, of ACM may span the right and left side of the heart. The umbrella definition of ACM encompasses disease mechanisms involving disruption of cell-cell adhesion, mechanotransduction, transcr...
Source: Current Cardiovascular Risk Reports - March 26, 2021 Category: Cardiology Source Type: research

Methods to Optimize Cryoballoon Ablation for Atrial Fibrillation to Minimize Risk of Adverse Outcomes and Arrhythmia Recurrences
AbstractPurpose of ReviewAtrial fibrillation (AF) is a chronic and progressive disorder, associated with effort intolerance, impairments in quality of life, and reduced survival. In patients with symptomatic atrial fibrillation, pulmonary vein isolation is an important treatment modality to reduce recurrent arrhythmia and improve quality of life. The purpose of this paper is to review practical considerations of the cryoballoon ablation procedure in order to minimize the risk of adverse procedural outcomes and arrhythmia recurrences.Recent FindingsEmerging evidence with respect to cryoablation dosing has beneficially refin...
Source: Current Cardiovascular Risk Reports - March 13, 2021 Category: Cardiology Source Type: research

Novel Approaches to Risk Stratification of In-Hospital Cardiac Arrest
AbstractPurpose of ReviewThis review aims to discuss strategies for patient risk stratification of in-hospital cardiac arrest and their challenges and limitations.Recent FindingsIn-hospital cardiac arrest is a significant cause of inpatient mortality, but survival to discharge rates remain low and have not significantly improved in the last three decades. As most patients are in a monitored setting and commonly show clinical deterioration prior to cardiac arrest, early intervention is thought to be the best way to both prevent and improve survival from cardiac arrest. However, detection of an impending cardiac arrest has p...
Source: Current Cardiovascular Risk Reports - January 31, 2021 Category: Cardiology Source Type: research

Novel Approaches to Risk Assessment for Ventricular Tachycardia Induction and Therapy
AbstractPurpose of ReviewVentricular tachycardia (VT) is a significant cause of cardiac sudden death (SCD) in various cardiomyopathy diseases. The following review will focus on the role of cardiac imaging in risk assessment for VT induction and novel technique and evidence regarding VT therapy including VT ablation and implantable cardiac defibrillator (ICD) therapy.Recent FindingsIn regard to VT risk stratification, characterizing VT substrate by cardiac imaging including cardiac magnetic resonance (CMR), multidetector computed tomography (MDCT), and positron-emission tomography (PET) has a significant role in predicting...
Source: Current Cardiovascular Risk Reports - January 11, 2021 Category: Cardiology Source Type: research

Correction to: Management of Pulmonary Arterial Hypertension
An Erratum to this paper has been published:https://doi.org/10.1007/s12170-020-00665-1 (Source: Current Cardiovascular Risk Reports)
Source: Current Cardiovascular Risk Reports - November 27, 2020 Category: Cardiology Source Type: research

Management of Pulmonary Arterial Hypertension
AbstractPurpose of ReviewThis review focuses on the therapeutic management and individualized approach to Group 1 pulmonary arterial hypertension (PAH), utilizing Food and Drug Administration-approved PAH-specific therapies and various interventional and surgical options for PAH.Recent FindingsThe paradigm for the optimal management of PAH has shifted in recent years. Upfront combination therapy with an endothelin receptor antagonist and a phosphodiesterase 5 inhibitor is now widely accepted as standard of care. In addition, there is increasing emphasis on starting prostanoids early in order to delay time to clinical worse...
Source: Current Cardiovascular Risk Reports - November 18, 2020 Category: Cardiology Source Type: research

CAR T Cell and BiTE Therapy —New Therapies, New Risks?
AbstractPurpose of ReviewT cell engaging immunotherapies, including chimeric antigen receptor (CAR) T cells and bispecific T cell engager (BiTE) antibodies have had recent and unprecedented success in the management of relapsing and refractory haematological malignancies. However, the potency of these novel immunotherapies is associated with significant toxicities. This review seeks to highlight the current understanding of cardiovascular toxicity-associated T cell engaging immunotherapies.Recent FindingsThe most common and best described toxicity due to T cell engaging immunotherapies is cytokine release syndrome (CRS). H...
Source: Current Cardiovascular Risk Reports - November 14, 2020 Category: Cardiology Source Type: research

Cancer, Cardiovascular Disease, and Body Weight: a Complex Relationship
AbstractPurpose of ReviewCardiovascular disease is the leading cause of death in the United States. Obese patients are at an increased risk of cardiovascular disease and weight loss can attenuate the risk. Cancer is the second leading cause of death and commonly associated with weight loss. This review focuses on the complex interaction between body weight, cardiovascular disease, and a cancer diagnosis.Recent FindingsThe cancer-associated mortality rate has steadily decreased over the last decade. Patients are living longer. Therefore, nonmalignant conditions, such as cardiovascular disease, have assumed an increased impo...
Source: Current Cardiovascular Risk Reports - November 7, 2020 Category: Cardiology Source Type: research