Novel Digital Technologies for Blood Pressure Monitoring and Hypertension Management

AbstractPurpose of ReviewHypertension is common, impacting an estimated 108 million US adults, and deadly, responsible for the deaths of one in six adults annually. Optimal management includes frequent blood pressure monitoring and antihypertensive medication titration, but in the traditional office-based care delivery model, patients have their blood pressure measured only intermittently and in a way that is subject to misdiagnosis with white coat or masked hypertension. There is a growing opportunity to leverage our expanding repository of digital technology to reimagine hypertension care delivery. This paper reviews existing and emerging digital tools available for hypertension management, as well as behavioral economic insights that could supercharge their impact.Recent FindingsDigitally connected blood pressure monitors offer an alternative to office-based blood pressure monitoring. A number of cuffless blood pressure monitors are in development but require further validation before they can be deployed for widespread clinical use. Patient-facing hubs and applications offer a means to transmit blood pressure data to clinicians. Though artificial intelligence could allow for curation of this data, its clinical use for hypertension remains limited to assessing risk factors at this time. Finally, text-based and telemedicine platforms are increasingly being employed to translate hypertension data into clinical outcomes with promising results.SummaryThe digital management of ...
Source: Current Cardiovascular Risk Reports - Category: Cardiology Source Type: research

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Dementia resulting from small vessel diseases (SVDs) of the brain is an emerging epidemic for which there is no treatment. Hypertension is the major risk factor for SVDs, but how hypertension damages the brain microcirculation is unclear. Here, we show that chronic hypertension in a mouse model progressively disrupts on-demand delivery of blood to metabolically active areas of the brain (functional hyperemia) through diminished activity of the capillary endothelial cell inward-rectifier potassium channel, Kir2.1. Despite similar efficacy in reducing blood pressure, amlodipine, a voltage-dependent calcium-channel blocker, p...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Hypertension is a leading cause of cognitive impairment and dementias. Such loss of brain health has a vascular component, but the mechanisms involved are poorly defined. In this issue of the JCI, Koide et al. provide evidence that end-organ effects of hypertension on capillary endothelium and inward-rectifier K+ channels (Kir2.1) impair integrated propagation of electrical signals and vasodilation upstream, resulting in reduced neurovascular coupling (NVC) despite neural activation. NVC was partly restored by amlodipine, but not losartan. Moreover, NVC was improved by eplerenone in the presence of losartan, suggesting a r...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
ConclusionBased on available information on pathophysiology and treatment of FH-1 in pregnancy, recommendations for the rational management of FH-1 in pregnancy are provided.
Source: Endocrine - Category: Endocrinology Source Type: research
ConclusionsThis study shows that vitamin D3 content is associated with the incidence of diabetes in people with high level of uric acid. This study offers a fresh perspective on the elements that influence the etiology of diabetes in hyperuricemia patients.
Source: Endocrine - Category: Endocrinology Source Type: research
TRADITIONALLY, high blood pressure has been deemed a predominantly male problem, but emerging research suggests it is as significant for women as it is for men. Hypertension, which rarely shows symptoms, is considered an important precursor for a host of cardiovascular conditions. A common complaint, however, could foreshadow hypertension and all consequent ailments.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Int J Med Sci. 2021 Aug 21;18(15):3526-3532. doi: 10.7150/ijms.60869. eCollection 2021.ABSTRACTBackground: Acute myocardial infarction is a relatively rare phenomenon in the young population. The incidence has nevertheless increased from years past, likely due to the presence of multiple risk factors from an increasingly younger age. Regardless of whether they have atherosclerotic coronary artery disease or normal coronary angiogram, young patients with risk factors for coronary artery disease (CAD), chest pain, and positive troponin, are initially treated in a similar fashion. Our goal was to shed light on whether risk fa...
Source: International Journal of Medical Sciences - Category: Biomedical Science Authors: Source Type: research
Int J Med Sci. 2021 Aug 1;18(15):3395-3402. doi: 10.7150/ijms.50568. eCollection 2021.ABSTRACTComputed tomography (CT) of the chest is one of the main diagnositic tools for coronavirus disease 2019 (COVID-19) infection. To document the chest CT findings in patients with confirmed COVID-19 and their association with the clinical severity, we searched related literatures through PubMed, MEDLINE, Embase, Web of Science (inception to May 4, 2020) and reviewed reference lists of previous systematic reviews. A total of 31 case reports (3768 patients) on CT findings of COVID-19 were included. The most common comorbid conditions w...
Source: International Journal of Medical Sciences - Category: Biomedical Science Authors: Source Type: research
AbstractPurposeDietary guidelines recommend to limit egg consumption to 4 servings per week but the relation between egg intake and health outcomes is still controversial. To evaluate the association of egg consumption and mortality risk in Italian adults and to investigate nutritional factors and serum lipids as potentially explaining such associations.MethodsLongitudinal analysis on 20,562 men and women aged  ≥ 35y, free from cardiovascular disease (CVD) and cancer belonging to the Moli-sani Study cohort (enrolled 2005–2010) followed up for a median of 8.2 years.ResultsIn multivariable-adjuste...
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
Considerable evidence documents the effectiveness and efficacy of bariatric surgery (BaS) in reducing the prevalence and severity of obesity-related comorbidities. Diastolic heart failure (DHF) is a condition with considerable morbidity and mortality, yet recalcitrant to medical-therapy. Our objectives were to assess whether BaS is associated with a decrease in hospital admissions for DHF; and further assess its impact upon DHF hospital admissions among patients with hypertension (HTN) and coronary artery disease (CAD).
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: ASMBS Guidelines/Statements Source Type: research
Nature Reviews Cardiology, Published online: 15 September 2021; doi:10.1038/s41569-021-00626-0Two new studies show that pharmacological blood pressure (BP) reduction is effective in older individuals and that a more intensive treatment with a lower BP threshold reduces the incidence of cardiovascular events in older patients with hypertension.
Source: Nature Reviews Cardiology - Category: Cardiology Authors: Source Type: research
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