Macrophages in the process of osseointegration around the implant and their regulatory strategies
CONCLUSIONS: Macrophages not only promote osseointegration through immunomodulation, but also secrete a variety of cytokines, which play a key role in the angiogenic and osteogenic phases of osseointegration. There is no "good" or "bad" difference between the M1 and M2 phenotypes of macrophages, but their timely presence and sequential switching play a crucial role in implant osseointegration. In the implant surface modification strategy, the induction of sequential activation of the M1 and M2 phenotypes of macrophages is a brighter prospect for implant surface modification than inducing the polarization of macrophages to ...
Source: Connective Tissue Research - January 3, 2024 Category: Research Authors: Xin Fang Duo Sun Yongli Li Xiao Han Yulu Gan Junjie Jiao Mengyuan Jiang Heyi Gong Yuanzheng Qi Jinghui Zhao Source Type: research
Macrophages in the process of osseointegration around the implant and their regulatory strategies
CONCLUSIONS: Macrophages not only promote osseointegration through immunomodulation, but also secrete a variety of cytokines, which play a key role in the angiogenic and osteogenic phases of osseointegration. There is no "good" or "bad" difference between the M1 and M2 phenotypes of macrophages, but their timely presence and sequential switching play a crucial role in implant osseointegration. In the implant surface modification strategy, the induction of sequential activation of the M1 and M2 phenotypes of macrophages is a brighter prospect for implant surface modification than inducing the polarization of macrophages to ...
Source: Connective Tissue Research - January 3, 2024 Category: Research Authors: Xin Fang Duo Sun Yongli Li Xiao Han Yulu Gan Junjie Jiao Mengyuan Jiang Heyi Gong Yuanzheng Qi Jinghui Zhao Source Type: research
Macrophages in the process of osseointegration around the implant and their regulatory strategies
CONCLUSIONS: Macrophages not only promote osseointegration through immunomodulation, but also secrete a variety of cytokines, which play a key role in the angiogenic and osteogenic phases of osseointegration. There is no "good" or "bad" difference between the M1 and M2 phenotypes of macrophages, but their timely presence and sequential switching play a crucial role in implant osseointegration. In the implant surface modification strategy, the induction of sequential activation of the M1 and M2 phenotypes of macrophages is a brighter prospect for implant surface modification than inducing the polarization of macrophages to ...
Source: Connective Tissue Research - January 3, 2024 Category: Research Authors: Xin Fang Duo Sun Yongli Li Xiao Han Yulu Gan Junjie Jiao Mengyuan Jiang Heyi Gong Yuanzheng Qi Jinghui Zhao Source Type: research
State transition and intercellular communication of synovial fibroblasts in response to chronic and acute shoulder injuries unveiled by single-cell transcriptomic analyses
CONCLUSION: We successfully generated the scRNA-seq transcriptomic atlas of the shoulder synovium, which provides a comprehensive understanding of the heterogeneity of synovial fibroblasts, their potential to undergo state transitions, and their intercellular communication in the context of chronic degenerative and acute traumatic shoulder diseases.PMID:38090785 | DOI:10.1080/03008207.2023.2295322 (Source: Connective Tissue Research)
Source: Connective Tissue Research - December 13, 2023 Category: Research Authors: Jiabao Ju Mingtai Ma Yichong Zhang Zhentao Ding Jianhai Chen Source Type: research
