Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research

Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research

Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research

Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research

Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research

Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research

Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research

Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research

Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research

Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research

Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research

Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research

Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research

Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research

Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research