A tribute to Doctor Arthur Veis
Connect Tissue Res. 2023 May 12. doi: 10.1080/03008207.2023.2213502. Online ahead of print.NO ABSTRACTPMID:37171225 | DOI:10.1080/03008207.2023.2213502 (Source: Connective Tissue Research)
Source: Connective Tissue Research - May 12, 2023 Category: Research Authors: Alix Deymier Source Type: research
Concentration-dependent effects of leptin on osteoarthritis-associated changes in phenotype of human chondrocytes
Connect Tissue Res. 2023 May 12. doi: 10.1080/03008207.2023.2214249. Online ahead of print.ABSTRACTMetabolic syndrome is a risk factor for osteoarthritis. Elevated leptin levels have been implicated as a potential cause of this association. Previous studies have shown that supra-physiological leptin concentrations can induce osteoarthritis-like changes in chondrocyte phenotype. Here, we tested the effects of leptin in the concentration range found in synovial fluid on chondrocyte phenotype. Chondrocytes isolated from macroscopically normal regions of cartilage within osteoarthritic joints from patients undergoing knee arth...
Source: Connective Tissue Research - May 12, 2023 Category: Research Authors: Julia Gb Primrose Lekha Jain Scott M Bolam A Paul Monk Jacob T Munro Nicola Dalbeth Raewyn C Poulsen Source Type: research
A biphasic calcium phosphate/acylated methacrylate gelatin composite hydrogel promotes osteogenesis and bone repair
CONCLUSIONS: BCP/GelMA composite hydrogel may be an effective artificial material for bone tissue engineering.PMID:37171221 | DOI:10.1080/03008207.2023.2212067 (Source: Connective Tissue Research)
Source: Connective Tissue Research - May 12, 2023 Category: Research Authors: None Ren-Jie Xu None Jin-Jin Ma Xiao Yu Xiao-Qiang Zhou Jing-Yu Zhang Ya-Dong Li Hui-Lin Yang None Saijilafu Guang-Xiang Chen Source Type: research
Current status and future trends of reconstructing a vascularized tissue-engineered trachea
Connect Tissue Res. 2023 May 12. doi: 10.1080/03008207.2023.2212052. Online ahead of print.ABSTRACTAlternative treatment of long tracheal defects remains one of the challenges faced by thoracic surgeons. Tissue engineering has shown great potential in addressing this regenerative medicine conundrum and the technology to make tracheal grafts using this technique is rapidly maturing, leading to unique therapeutic approaches. However, the clinical application of tissue-engineered tracheal implants is limited by insufficient revascularization. Among them, realizing the vascularization of a tissue-engineered trachea is the most...
Source: Connective Tissue Research - May 12, 2023 Category: Research Authors: Ziqing Shen Tian Xia Jun Zhao Shu Pan Source Type: research
A tribute to Doctor Arthur Veis
Connect Tissue Res. 2023 May 12. doi: 10.1080/03008207.2023.2213502. Online ahead of print.NO ABSTRACTPMID:37171225 | DOI:10.1080/03008207.2023.2213502 (Source: Connective Tissue Research)
Source: Connective Tissue Research - May 12, 2023 Category: Research Authors: Alix Deymier Source Type: research
Concentration-dependent effects of leptin on osteoarthritis-associated changes in phenotype of human chondrocytes
Connect Tissue Res. 2023 May 12. doi: 10.1080/03008207.2023.2214249. Online ahead of print.ABSTRACTMetabolic syndrome is a risk factor for osteoarthritis. Elevated leptin levels have been implicated as a potential cause of this association. Previous studies have shown that supra-physiological leptin concentrations can induce osteoarthritis-like changes in chondrocyte phenotype. Here, we tested the effects of leptin in the concentration range found in synovial fluid on chondrocyte phenotype. Chondrocytes isolated from macroscopically normal regions of cartilage within osteoarthritic joints from patients undergoing knee arth...
Source: Connective Tissue Research - May 12, 2023 Category: Research Authors: Julia Gb Primrose Lekha Jain Scott M Bolam A Paul Monk Jacob T Munro Nicola Dalbeth Raewyn C Poulsen Source Type: research
Contribution of Immune Cells to Intervertebral Disc Degeneration and the Potential of Immunotherapy
Connect Tissue Res. 2023 May 10. doi: 10.1080/03008207.2023.2212051. Online ahead of print.ABSTRACTSubstantial evidence supports that chronic low back pain is associated with intervertebral disc degeneration (IDD), which is accompanied by decreased cell activity and matrix degradation. The role of immune cells, especially macrophages, in a variety of diseases has been extensively studied; therefore, their role in IDD has naturally attracted widespread scholarly interest. The IVD is considered to be an immunologically-privileged site given the presence of physical and biological barriers that include an avascular microenvir...
Source: Connective Tissue Research - May 10, 2023 Category: Research Authors: Hao Xu Juan Li Qinming Fei Libo Jiang Source Type: research
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research
Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research
Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research
Comparison of methods for the isolation and culture of Migratory chondroprogenitors from Human articular cartilage
CONCLUSIONS: MCPs can be preferably isolated by the any of the three above methods based on the investigator's discretion. In the case of small cartilage samples similar to the MCP3 group, the isolation of MCP is plausible, keeping in mind the additional time required.PMID:37092666 | DOI:10.1080/03008207.2023.2202266 (Source: Connective Tissue Research)
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Elizabeth Vinod Ganesh Parasuraman Abel Livingston Soosai Manickam Amirtham Grace Rebekah J Jeya Lisha Alfred Job Daniel Solomon Sathishkumar Source Type: research
Ovariectomy with simulated vaginal delivery to establish a rat model for pelvic organ prolapse
Connect Tissue Res. 2023 Apr 24:1-13. doi: 10.1080/03008207.2023.2199091. Online ahead of print.ABSTRACTThe widespread prevalence of Pelvic Organ Prolapse (POP) and the paucity of ongoing treatments prompted us to develop a unique rat model combining ovariectomy and simulated vaginal delivery. We hypothesized that the tissue changes caused by low hormone levels and mechanical stretch could complement each other. Thus, the combined model can potentially mimic the collagen metabolism of vaginal wall tissue as well as mechanical stretch properties to complement disease progression in POP. Ovariectomy with sequential simulated...
Source: Connective Tissue Research - April 24, 2023 Category: Research Authors: Tao Guo Zhe Du Xiu-Qi Wang Jing-He Lang Zhi-Jing Sun Source Type: research
