State transition and intercellular communication of synovial fibroblasts in response to chronic and acute shoulder injuries unveiled by single-cell transcriptomic analyses

CONCLUSION: We successfully generated the scRNA-seq transcriptomic atlas of the shoulder synovium, which provides a comprehensive understanding of the heterogeneity of synovial fibroblasts, their potential to undergo state transitions, and their intercellular communication in the context of chronic degenerative and acute traumatic shoulder diseases.PMID:38090785 | DOI:10.1080/03008207.2023.2295322

Source: Connective Tissue Research - December 13, 2023 Category: Research Authors: Jiabao Ju Mingtai Ma Yichong Zhang Zhentao Ding Jianhai Chen Source Type: research