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Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Medically assisted hydration for adults receiving palliative care
CONCLUSIONS: Since the previous update of this review, we have found one new study. In adults receiving palliative care in the end stage of their illness, there remains insufficient evidence to determine whether MAH improves QoL or prolongs survival, compared with placebo or standard care. Given that all participants were inpatients with advanced cancer at end of life, our findings are not transferable to adults receiving palliative care in other settings, for non-cancer, dementia or neurodegenerative diseases, or for those with an extended prognosis. Clinicians will need to make decisions based on the perceived benefits a...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Emma J Buchan Alison Haywood William Syrmis Phillip Good Source Type: research

Cranberries for treating urinary tract infections
CONCLUSIONS: After a thorough search, no RCTs which assessed the effectiveness of cranberry juice for the treatment of UTIs were found. Therefore, at the present time, there is no good quality evidence to suggest that it is effective for the treatment of UTIs. Well-designed parallel-group, double-blind studies comparing cranberry juice and other cranberry products versus placebo to assess the effectiveness of cranberry juice in treating UTIs are needed. Outcomes should include a reduction in symptoms, sterilisation of the urine, side effects and adherence to therapy. The dosage (amount and concentration) and duration of th...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Ruth G Jepson Lara Mihaljevic Jonathan C Craig Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Medically assisted hydration for adults receiving palliative care
CONCLUSIONS: Since the previous update of this review, we have found one new study. In adults receiving palliative care in the end stage of their illness, there remains insufficient evidence to determine whether MAH improves QoL or prolongs survival, compared with placebo or standard care. Given that all participants were inpatients with advanced cancer at end of life, our findings are not transferable to adults receiving palliative care in other settings, for non-cancer, dementia or neurodegenerative diseases, or for those with an extended prognosis. Clinicians will need to make decisions based on the perceived benefits a...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Emma J Buchan Alison Haywood William Syrmis Phillip Good Source Type: research

Cranberries for treating urinary tract infections
CONCLUSIONS: After a thorough search, no RCTs which assessed the effectiveness of cranberry juice for the treatment of UTIs were found. Therefore, at the present time, there is no good quality evidence to suggest that it is effective for the treatment of UTIs. Well-designed parallel-group, double-blind studies comparing cranberry juice and other cranberry products versus placebo to assess the effectiveness of cranberry juice in treating UTIs are needed. Outcomes should include a reduction in symptoms, sterilisation of the urine, side effects and adherence to therapy. The dosage (amount and concentration) and duration of th...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Ruth G Jepson Lara Mihaljevic Jonathan C Craig Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Medically assisted hydration for adults receiving palliative care
CONCLUSIONS: Since the previous update of this review, we have found one new study. In adults receiving palliative care in the end stage of their illness, there remains insufficient evidence to determine whether MAH improves QoL or prolongs survival, compared with placebo or standard care. Given that all participants were inpatients with advanced cancer at end of life, our findings are not transferable to adults receiving palliative care in other settings, for non-cancer, dementia or neurodegenerative diseases, or for those with an extended prognosis. Clinicians will need to make decisions based on the perceived benefits a...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Emma J Buchan Alison Haywood William Syrmis Phillip Good Source Type: research

Cranberries for treating urinary tract infections
CONCLUSIONS: After a thorough search, no RCTs which assessed the effectiveness of cranberry juice for the treatment of UTIs were found. Therefore, at the present time, there is no good quality evidence to suggest that it is effective for the treatment of UTIs. Well-designed parallel-group, double-blind studies comparing cranberry juice and other cranberry products versus placebo to assess the effectiveness of cranberry juice in treating UTIs are needed. Outcomes should include a reduction in symptoms, sterilisation of the urine, side effects and adherence to therapy. The dosage (amount and concentration) and duration of th...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Ruth G Jepson Lara Mihaljevic Jonathan C Craig Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Medically assisted hydration for adults receiving palliative care
CONCLUSIONS: Since the previous update of this review, we have found one new study. In adults receiving palliative care in the end stage of their illness, there remains insufficient evidence to determine whether MAH improves QoL or prolongs survival, compared with placebo or standard care. Given that all participants were inpatients with advanced cancer at end of life, our findings are not transferable to adults receiving palliative care in other settings, for non-cancer, dementia or neurodegenerative diseases, or for those with an extended prognosis. Clinicians will need to make decisions based on the perceived benefits a...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Emma J Buchan Alison Haywood William Syrmis Phillip Good Source Type: research

Cranberries for treating urinary tract infections
CONCLUSIONS: After a thorough search, no RCTs which assessed the effectiveness of cranberry juice for the treatment of UTIs were found. Therefore, at the present time, there is no good quality evidence to suggest that it is effective for the treatment of UTIs. Well-designed parallel-group, double-blind studies comparing cranberry juice and other cranberry products versus placebo to assess the effectiveness of cranberry juice in treating UTIs are needed. Outcomes should include a reduction in symptoms, sterilisation of the urine, side effects and adherence to therapy. The dosage (amount and concentration) and duration of th...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Ruth G Jepson Lara Mihaljevic Jonathan C Craig Source Type: research

Positioning for lumbar puncture in newborn infants
CONCLUSIONS: When compared to sitting position, lateral decubitus position probably results in little to no difference in successful lumbar puncture procedure at first attempt. None of the included studies reported the total number of lumbar puncture attempts as specified in this review. Furthermore, infants in a sitting position likely experience less episodes of bradycardia and oxygen desaturation than in the lateral decubitus, and there may be little to no difference in episodes of apnea. Lateral decubitus position results in little to no difference in time to perform the lumbar puncture compared to sitting position. Pa...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Sara Pessano Matteo Bruschettini Marcus Glenton Prescott Olga Romantsik Source Type: research

Medically assisted hydration for adults receiving palliative care
CONCLUSIONS: Since the previous update of this review, we have found one new study. In adults receiving palliative care in the end stage of their illness, there remains insufficient evidence to determine whether MAH improves QoL or prolongs survival, compared with placebo or standard care. Given that all participants were inpatients with advanced cancer at end of life, our findings are not transferable to adults receiving palliative care in other settings, for non-cancer, dementia or neurodegenerative diseases, or for those with an extended prognosis. Clinicians will need to make decisions based on the perceived benefits a...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Emma J Buchan Alison Haywood William Syrmis Phillip Good Source Type: research

Cranberries for treating urinary tract infections
CONCLUSIONS: After a thorough search, no RCTs which assessed the effectiveness of cranberry juice for the treatment of UTIs were found. Therefore, at the present time, there is no good quality evidence to suggest that it is effective for the treatment of UTIs. Well-designed parallel-group, double-blind studies comparing cranberry juice and other cranberry products versus placebo to assess the effectiveness of cranberry juice in treating UTIs are needed. Outcomes should include a reduction in symptoms, sterilisation of the urine, side effects and adherence to therapy. The dosage (amount and concentration) and duration of th...
Source: Cochrane Database of Systematic Reviews - December 14, 2023 Category: General Medicine Authors: Ruth G Jepson Lara Mihaljevic Jonathan C Craig Source Type: research