Characteristics of patients with initial diagnosis of systemic lupus erythematosus in emergency department and their outcomes: a retrospective single-center study
ConclusionUnderstanding disease patterns can contribute to physicians providing accurate diagnosis and efficient care for SLE patients in ED.Key Points•Systemic lupus erythematosus, a complex autoimmune disorder, can have either a chronic or a relapsing and remitting disease course. The disease can involve acute events or severe comorbidities, and frequent visits to the emergency department (ED) are inevitable.•It is essential to better understand which comorbidities can lead to emergency department visits. Accurate clinical diagnosis and appropriate interventions from ED physicians can have a strong impact on the prog...
Source: Clinical Rheumatology - December 27, 2023 Category: Rheumatology Source Type: research

Rebuttal Letter to “The efficacy and reliability of English YouTube videos as a source of information for pregnant rheumatoid arthritis patients”
(Source: Clinical Rheumatology)
Source: Clinical Rheumatology - December 27, 2023 Category: Rheumatology Source Type: research

Letter to the Editor on “The efficacy and reliability of English YouTube videos as a source of information for pregnant rheumatoid arthritis patients”
(Source: Clinical Rheumatology)
Source: Clinical Rheumatology - December 27, 2023 Category: Rheumatology Source Type: research

Characteristics of patients with initial diagnosis of systemic lupus erythematosus in emergency department and their outcomes: a retrospective single-center study
ConclusionUnderstanding disease patterns can contribute to physicians providing accurate diagnosis and efficient care for SLE patients in ED.Key Points•Systemic lupus erythematosus, a complex autoimmune disorder, can have either a chronic or a relapsing and remitting disease course. The disease can involve acute events or severe comorbidities, and frequent visits to the emergency department (ED) are inevitable.•It is essential to better understand which comorbidities can lead to emergency department visits. Accurate clinical diagnosis and appropriate interventions from ED physicians can have a strong impact on the prog...
Source: Clinical Rheumatology - December 27, 2023 Category: Rheumatology Source Type: research

Rebuttal Letter to “The efficacy and reliability of English YouTube videos as a source of information for pregnant rheumatoid arthritis patients”
(Source: Clinical Rheumatology)
Source: Clinical Rheumatology - December 27, 2023 Category: Rheumatology Source Type: research

Letter to the Editor on “The efficacy and reliability of English YouTube videos as a source of information for pregnant rheumatoid arthritis patients”
(Source: Clinical Rheumatology)
Source: Clinical Rheumatology - December 27, 2023 Category: Rheumatology Source Type: research

ToRaRI (Tofacitinib in Rheumatoid Arthritis a Real-Life experience in Italy): Effectiveness, safety profile of tofacitinib and concordance between patient-reported outcomes and physician's global assessment of disease activity in a retrospective study in Central-Italy
ConclusionsTofacitinib is safe and effective in our RA cohort. It induces higher remission rates in patients naive to bDMARDs, suggesting that there may be a benefit using it as first-line therapy. Additionally, improvement in PROs was consistent with PhGA scores, demonstrating how tofacitinib affects both the objective and subjective components of disease activity.Key Points1.JAK inhibitors are considered at a similar level as biologic agents in terms of effectiveness.2.After ORAL-Surveillance results, real-world data are needed to assess the benefit/risk profile of Jaki.3.Disagreement between patients and physicians has ...
Source: Clinical Rheumatology - December 23, 2023 Category: Rheumatology Source Type: research

Understanding muscle coordination during gait based on muscle synergy and its association with symptoms in patients with knee osteoarthritis
ConclusionsMuscle coordination was altered in patients with KOA. The correlation between muscle coordination and KOA may be attributed to the knee-related symptoms.Key points• Patients with knee osteoarthritis (OA) experienced a deterioration in muscle coordination when walking.• Loss of muscle coordination was associated with severe knee-related symptoms in knee OA.• Considering muscle coordination as a knee OA symptom-related factor may provide improved treatment. (Source: Clinical Rheumatology)
Source: Clinical Rheumatology - December 22, 2023 Category: Rheumatology Source Type: research

Burden of Disease in Psoriatic Arthritis in Latin America: a Systematic  Literature Review
ConclusionsThe available information reports a considerable burden of disease in patients with PsA in Latin America, with involvement of quality of life associated with disability in relation to disease activity and its various manifestations. Future research and funding efforts should be aimed at generating more standardized information about the impact of PsA in the region.Key Points•The functional involvement related to disease activity, the impact on the quality of life, and the frequency of cardiometabolic and psychological comorbidities are remarkable in Latin American patients with PsA.•The current synthesis off...
Source: Clinical Rheumatology - December 20, 2023 Category: Rheumatology Source Type: research

Performance of myotonometer in the assessment of skin involvement in systemic sclerosis
ConclusionsOur findings emphasize the potential utility of the myotonometer for assessing skin properties and differentiating SSc patients from controls, demonstrating its promise as a valuable clinical evaluation tool in this context.Key Points•The myotonometer displayed excellent intra- and inter-examiner reproducibility for assessing skin properties.•Skin tone and stiffness parameters well correlated with the mRSS scores.•The myotonometer can distinguish patients with diffuse cutaneous SSc from healthy controls. (Source: Clinical Rheumatology)
Source: Clinical Rheumatology - December 20, 2023 Category: Rheumatology Source Type: research

Burden of Disease in Psoriatic Arthritis in Latin America: a Systematic  Literature Review 
ConclusionsThe available information reports a considerable burden of disease in patients with PsA in Latin America, with involvement of quality of life associated with disability in relation to disease activity and its various manifestations. Future research and funding efforts should be aimed at generating more standardized information about the impact of PsA in the region.Key Points•The functional involvement related to disease activity, the impact on the quality of life, and the frequency of cardiometabolic and psychological comorbidities are remarkable in Latin American patients with PsA.•The current synthesis off...
Source: Clinical Rheumatology - December 20, 2023 Category: Rheumatology Source Type: research

Performance of myotonometer in the assessment of skin involvement in systemic sclerosis
ConclusionsOur findings emphasize the potential utility of the myotonometer for assessing skin properties and differentiating SSc patients from controls, demonstrating its promise as a valuable clinical evaluation tool in this context.Key Points•The myotonometer displayed excellent intra- and inter-examiner reproducibility for assessing skin properties.•Skin tone and stiffness parameters well correlated with the mRSS scores.•The myotonometer can distinguish patients with diffuse cutaneous SSc from healthy controls. (Source: Clinical Rheumatology)
Source: Clinical Rheumatology - December 20, 2023 Category: Rheumatology Source Type: research