Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee
We present SONK in bone scintigraphy and SPECT/CT in 65-year-old man with sudden worsening knee pain and normal radiographs. SPECT/CT revealed intense uptake in subchondral area of left femoral medial condyle, which can be differed from progressed osteoarthritic change of the knee joints suspected on planar scintigraphy. Subsequently performed MRI showed characteristic finding of SONK. Total knee replacement arthroplasty was performed with final histological diagnosis of SONK. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
A Rare Extramedullary Involvement Site in Patients With Multiple Myeloma: Stomach
We present 2 cases with gastric involvement of MM that were shown by 18F-FDG PET/CT and confirmed as plasma cell infiltration pathologically. 18F-FDG PET/CT studies of MM patients should be interpreted carefully for gastrointestinal involvement, and it should be kept in mind that it can mimic other malignancies. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Suprasellar Hemangioblastoma on 68Ga-DOTATATE PET/CT
Von Hippel-Lindau (VHL) disease is an autosomal dominant hereditary cancer syndrome that is characterized by the presence of various malignant and benign tumors, including retinal and central nervous system hemangioblastomas. Hemangioblastomas are highly vascular tumors that can occur sporadically or within VHL disease. Herein, we present 68Ga-DOTATATE PET/CT findings of a unique case of suprasellar hemangioblastoma in a 52-year-old man with VHL disease. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Azygos Vein Enlargement Secondary to Superior Vena Cava Syndrome on 18F-FDG PET/CT
Obstruction of the blood flow from the superior vena cava (SVC) to the right atrium causes the SVC syndrome. The azygos system is the most important way to overcome SVC obstruction. Azygos vein enlargement can be seen secondary to the SVC syndrome. Although a few cases showing 18F-FDG uptake along the SVC in SVC syndrome were reported before, 18F-FDG PET/CT findings of azygos vein enlargement have not been documented yet. Herein, we presented an intriguing case of azygos vein enlargement secondary to SVC syndrome on 18F-FDG PET/CT. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Comparison of 68Ga-FAPI PET and 18F-FDG PET Findings in a Patient With Bilateral Breast Cancer of 2 Different Histopathologies
We present the findings of 18F-FDG PET and 68Ga–fibroblast activation protein PET scans done in a case of bilateral breast carcinoma with 2 different histopathology, left breast tubulolobular carcinoma and right breast invasive breast carcinoma of no special type. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Management of a Patient With Metastatic Gastrointestinal Neuroendocrine Tumor and Meningioma Submitted to Peptide Receptor Radionuclide Therapy With 177Lu-DOTATATE
A 76-year-old woman affected by pancreatic neuroendocrine tumor previously subjected to surgery with progressive liver disease and a concomitant mild symptomatic meningioma of the left pontocerebellar angle underwent 4 cycles of peptide receptor radionuclide therapy with 177Lu-DOTATATE. A prophylactic therapy with corticosteroids was carried out before each treatment cycle, and the neurosurgery unit was alerted in case of cerebral edema and related neurologic symptoms. A 68Ga-DOTATOC PET/CT scan performed after the completion of the 4 cycles’ treatment documented a hepatic partial response and a substantial stability of ...
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Diplopia Related to a Pediatric Cervical Rhabdoid Tumor in 18F-FDG PET
We describe the case of an 8-year-old boy with extrarenal rhabdoid tumor in the right carotid space. An MRI and an 18F-FDG PET/CT were performed for the diagnostic workup. There was no uptake in the lateral rectus oculomotor muscle unlike all other oculomotor muscles. The ophthalmological examination found a diplopia confirmed by the Lancaster test. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
SPECT/CT Lymphoscintigraphy Guidance Simplifies and Improves Targeted Axillary Dissection of the Clipped Nodes After Neoadjuvant Chemotherapy in Initially Node-Positive Breast Cancer
Conclusion
SPECT/CT lymphoscintigraphy seems feasible to determine the clipped LNs intraoperatively without requiring additional invasive methods in most of the patients. This technique simplifies and improves targeted axillary dissection of the clipped axLNs after NAC in initially node-positive breast cancer and can be adapted to clinical practice with further investigations. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Impact of FDG PET/CT Scan in Changing Management of Well-Differentiated Neuroendocrine Tumors With Ki67 Index Less Than or Equal to 5%
Conclusions
In lower-grade NET, FDG positivity was seen in a sizable number of the cases, and this led to change in management in 17.4% of the cases. Specific clinical features could be utilized to successfully discriminate between FDG-avid and non–FDG-avid disease in lower-grade NETs, and this had impact in management change as well. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Solitary Central Nervous System Relapse of Posttransplant Lymphoproliferative Disorder on 18F-FDG PET/CT
A 41-year-old woman received stem cell transplant due to acute myeloid leukemia. Six months after the stem cell transplant, the patient experienced monomorphic PTLD (posttransplant lymphoproliferative disorder) and underwent chemotherapy. Postchemotherapy PET/CT did not show any abnormal 18F-FDG accumulation in the scanned body, including brain. Four months later, she presented with nausea and vomiting. Brain MRI showed a lesion in the right temporal lobe. In addition to the abnormal 18F-FDG accumulation in the brain, no other abnormal foci were noted in the torso PET/CT. Biopsy pathology confirmed the diagnosis of monomor...
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Epiglottic Polymorphous Adenocarcinoma With Multiple Bone Metastases Detected by 68Ga-FAPI PET/CT
Polymorphous adenocarcinoma (PAC) is generally an indolent tumor that mostly commonly affects the minor salivary gland. Polymorphous adenocarcinoma with distant metastases is extremely rare. In this case, we reported 18F-FDG and 68Ga-FAPI PET/CT imaging findings in a rare case of epiglottic PAC with multiple bone metastases. 68Ga-FAPI PET/CT showed superiority over 18F-FDG PET/CT for detecting the primary and metastatic PAC. This case highlighted that 68Ga-FAPI may be a promising radiopharmaceutical in the diagnosis of PAC, especially for detecting the PACs arising in uncommon sites. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
FDG PET/CT in Unilateral Renal Metastasis From Colon Cancer
We describe FDG PET/CT findings in a case with a right renal and a postcaval lymph node metastasis from colon cancer. Both the renal tumor and postcaval lymph node showed increased FDG uptake with SUVmax of 6.1 for the renal tumor and 5.5 for the postcaval lymph node. The imaging findings mimicked a primary renal cancer with postcaval lymph node metastasis. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Left Forearm Langerhans Cell Sarcoma Demonstrated by 18F-FDG PET/CT
We report FDG PET/CT findings of Langerhans cell sarcoma in the left forearm of a 77-year-old woman who presented with progressive enlargement of the left forearm mass for over 2 months. 18F-FDG PET/CT demonstrated a high FDG uptake by the mass along with several FDG-avid enlarged lymph nodes in the left arm and axilla. Pathology examination of the biopsied specimen from the left forearm mass led to a diagnosis of Langerhans cell sarcoma. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
FDG PET/CT in a Case With Cellular Schwannoma of the Kidney
We describe contrast-enhanced CT and FDG PET/CT findings in a case with renal cellular schwannoma. Contrast-enhanced CT showed the enhancing tumor was located in the anterior middle portion of the left kidney, encasing the renal vessels and compressing the renal pelvis. The tumor showed inhomogeneous FDG uptake with SUVmax of 8.6 mimicking renal cell carcinoma. This case indicates renal schwannoma should be included in the differential diagnosis of FDG-avid renal lesions. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Elevated 68Ga-FAPI Uptake by Primary Benign Intraosseous Meningioma
We present the 68Ga–fibroblast activation protein inhibitor (FAPI) PET/CT findings of primary intraosseous meningioma in a 71-year-old woman. 68Ga-FAPI PET/CT revealed an intraosseous mass in the right parietal bone with increased FAPI activity. Primary skull malignancy was suspected. However, pathological examination after resection of the mass in the right parietal bone confirmed the diagnosis of benign meningioma (WHO I). A final diagnosis of benign intraosseous meningioma was made. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
