Intra-articular Treatment of Digital Osteoarthritis by Radiosynoviorthesis—Clinical Outcome in Long-term Follow-up
Conclusions This article confirms that RSO is a suitable treatment option for digital joint OA with a proven synovitis. The analgesic effect is long-lasting and comparable to the success of RSO in patients with rheumatoid arthritis. Osteoarthritis (OA) is a degenerative joint disease, leading to increasing pain and disability. In digital joints, OA results in a reduced quality of life with significantly restricted daily manual activities. Inflammatory processes are increasingly recognized as an important part of OA. Thus, a local anti-inflammatory treatment using intra-articularly applied radiocolloids can be used f...
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Predicting Treatment Response in Primary Aldosteronism Using 11C-Metomidate Positron Emission Tomography
Conclusion According to adrenal CT findings, MTO PET presented different uptake patterns. Patients with PA under medical treatment showed significantly lower tracer uptake in responders. Thus, MTO PET may be a useful imaging biomarker to predict medical treatment outcome. Multicenter prospective study with a larger number of patients is needed for further validation. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Comparison of 18F-DOPA and 18F-DTBZ for PET/CT Imaging of Idiopathic Parkinson Disease
Conclusion 18F-DTBZ and 18F-DOPA could reflect the same level of dopaminergic neuron degeneration for PD in early stages, and they have the consistent visual analysis results. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Correlation of Global and Regional Amyloid Burden by 18F-Florbetaben PET/CT With Cognitive Impairment Profile and Severity
Conclusion Semiquantitative analysis of amyloid PET by SUVR values revealed a significant correlation between amyloid burden and CI severity, although only in women. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - October 17, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research

Quality and Safety in Healthcare, Part LXXXIII: The Culture of Safety in High Reliability Organizations
A safety culture encourages the reporting of mistakes so that all can learn from them and remedy underlying system problems. However, errors will only be reported in a culture in which most types of common human errors are not punished because all humans make errors, and usually there are underlying system problems contributing to this. All healthcare errors must be viewed partly as opportunities to improve. A safety culture includes good leadership, communication, learning, collaboration, mindfulness, medicine that is based on evidence and best practice, and care that is centered on the patient. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: From the American College of Nuclear Medicine Source Type: research

Alterations in 18F-FDG PET/MRI and 15O-Water PET Brain Findings in Patients With Neurological Symptoms After COVID-19 Vaccination: A Pilot Study: Reply
No abstract available (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

Re: Alterations in 18F-FDG PET/MRI and 15O-Water PET Brain Findings in Patients With Neurological Symptoms After COVID-19 Vaccination: A Pilot Study
No abstract available (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

Dual-Time-Point 18F-Fluorocholine PET/CT Improves Characterization of Thyroid Nodules in Patients Referred for Primary Hyperparathyroidism: A Proof of Concept Study: Reply
No abstract available (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

Re: Dual-Time-Point 18F-Fluorocholine PET/CT Improves Characterization of Thyroid Nodules in Patients Referred for Primary Hyperparathyroidism: A Proof-of-Concept Study
No abstract available (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research

68Ga-FAPI-46 and 18F-FDG in Advanced Metastatic Pancreatic Cancer
Recently imaging with new PET radiotracers that act as fibroblast activation protein inhibitors (FAPIs) showed promising results in oncology and even nononcology imaging. Here we report a case of advanced pancreatic adenocarcinoma, imaged with both 18F-FDG and 68Ga-FAPI-46 PET/CT scans. The result indicated that imaging with 68Ga-FAPI-46 showed significant improvement in detection of metastases as well as local malignancy recurrence. Moreover, the intensity and SUVs of the lesions were higher in 68Ga-FAPI-46 scan compared with 18F-FDG. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Incidental Detection of Radiotracer Uptake in Spindle Cell Lipoma on 18F-PSMA PET/CT
An 84-year-old man underwent 18F–prostate-specific membrane antigen (PSMA) PET/CT for staging of a newly diagnosed prostate adenocarcinoma. PET/CT revealed high 18F-PSMA uptake in a thigh mass, which was initially suspected for a metastasis. Histopathology revealed a rare entity of spindle cell lipoma, which should be added to the reported list of neoplasms that can show “false-positive” PSMA uptake during evaluation of patients with prostate carcinoma representing a potential interpretative pitfall. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Solitary Fibrous Tumor of the Bone Detected by FDG PET/CT
Solitary fibrous tumor as a rare mesenchymal tumor can occur in a wide variety of body sites, including serosal membranes, liver, lung, and deep soft tissues; however, primary tumor arising in bone is rarely documented. Herein, we reported the MRI, bone scan, and FDG PET/CT findings of a primary spinal solitary fibrous tumor in a 39-year-old woman. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Resolution of Misleading COVID-19 Vaccination–Related Nodal and Splenic FDG Uptake in the Follow-up Study
Newly diagnosed low-grade bilateral breast lymphoma in 63-year-old woman demonstrated intense FDG uptake in the left axillary lymph nodes and the spleen, concerning for lymphomatous involvement. Subsequent ultrasound-guided biopsy did not demonstrate any pathologic left axillary lymph nodes. Further investigation revealed COVID-19 vaccination in the left arm, 5 days prior to the 18F-FDG PET/CT study. Six-month follow-up 18F-FDG PET/CT showed resolution of the intense FDG uptake in the left axillary lymph nodes and spleen without any treatment, suggesting a self-remitting acute local and systemic immune response to COVID-19...
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

Tracheitis Diagnosed With 68Ga-PSMA PET/CT in a Patient With COVID-19
A 57-year-old man with newly diagnosed with prostate cancer was admitted to our department for 68Ga–prostate-specific membrane antigen PET/CT imaging. The patient, who was asymptomatic at the time of imaging, had increased diffuse 68Ga–prostate-specific membrane antigen uptake in the trachea on PET/CT. No ground-glass density suggestive of pneumonia in both lungs was observed. The patient, whose symptoms developed 2 days after PET/CT imaging, was diagnosed with coronavirus disease 2019 by real-time polymerase chain reaction. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research

68Ga-FAPI-04 PET/CT in Epithelioid Hemangioendothelioma With Pleura and Bone Metastases
We report a case of epithelioid hemangioendothelioma with pleura and bone metastases on 68Ga-FAPI-04 PET/CT in a 65-year-old woman who underwent surgery and chemotherapy. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research