68Ga-DOTA-FAPI-04 PET/CT Imaging of Tracheal Mucoepidermoid Carcinoma
A 23-year-old woman presented with a dry cough and dyspnea. Contrast-enhanced CT revealed an intratracheal space-occupying lesion with continuous homogeneous enhancement and airway stenosis. The patient then underwent 68Ga-DOTA-FAPI-04 PET/CT, which showed increased uptake of FAPI-04 by the lesion. Postoperative pathology confirmed the lesion as tracheal mucoepidermoid carcinoma. This case reports a rare site of mucoepidermoid carcinoma and highlights the potential utility of 68Ga-DOTA-FAPI-04 PET/CT for the diagnosis of tracheal mucoepidermoid carcinoma. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
The Onset of Sarcoidosis After COVID-19 Vaccination Revealed by the 18F-FDG PET
We presented 18F-FDG PET/CT findings of sarcoidosis in a previously healthy 43-year-old man who presented intermittent cough after the third dose of COVID-19 vaccination. 18F-FDG PET/CT showed high uptake of one solitary nodule in the right middle lobe, mediastinal lymph nodes, bilateral hila, and multiple nodules under the right pleura, mimicking the malignancy. Nevertheless, the biopsy confirmed distinct noncaseating granulomas. This case emphasizes the onset of sarcoidosis revealed by 18F-FDG PET/CT after COVID-19 vaccination. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
11C-Acetate PET/CT Detects Reactive Astrogliosis Helping Glioma Classification
Conclusions
High 11C-ACE uptake is associated with high-grade IDH1-wt tumors, thus facilitating differentiation from high-grade IDH1-mt and low-grade gliomas. In particular, low 11C-ACE uptake in ODs is advantageous in overcoming the limitation of radiolabeled amino acid tracers. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Early Recurrence Detection of Glioma Using 18F-Fluorocholine PET/CT: GliReDe Pilot Study
Conclusions
18F-fluorocholine PET/CT was helpful for increasing the diagnostic confidence in the cases of MRI doubtful for recurrence in order to avoid a delayed diagnosis. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Comparison of Preoperative Imaging Modalities for the Assessment of Malignant Potential of Pancreatic Cystic Lesions: A Network Meta-analysis
Conclusions
The results from this NMA suggest that 18F-FDG PET is the best preoperative imaging modality for differentiating malignant from benign PCLs and that it can be used for the preoperative evaluation of PCLs. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Diagnostic Test Accuracy of 18F-FDG PET or PET/CT in Merkel Cell Carcinoma
Conclusion
18F-FDG PET/CT showed an excellent performance for diagnosis of MCC. The likelihood ratio scattergram indicated that 18F-FDG PET or PET/CT is useful for exclusion and confirmation of MCC. Further large multicenter studies would be necessary to substantiate the diagnostic accuracy of 18F-FDG PET or PET/CT for MCC patients. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - September 10, 2022 Category: Nuclear Medicine Tags: Original Articles Source Type: research
Quality and Safety in Health Care, Part LXXXII: Introduction to High Reliability Organizations
Reports from the Institute of Medicine regarding the number of errors in medicine leading to fatalities prompted a major review of medical practices and a move to make medical systems high reliability organizations. Many of the concepts used today to improve performance in health care are borrowed from what has been learned from successes and accidents in other industries, especially in the aviation, space, and nuclear power programs. An emphasis on excellent leadership and communication, the knowledge that there needs to be an emphasis on system failures rather than human failures, and having a safety culture that encoura...
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: From the American College of Nuclear Medicine Source Type: research
FDG PET/CT in a Patient With Syphilis Suspected of Having Penile Cancer
A 58-year-old man with large penile wound and enlarged regional lymph node was suspected of having disseminated penile cancer. FDG PET/CT for primary staging showed high FDG uptake on penis and in several enlarged lymph nodes. However, biopsies revealed no signs of malignancy, but ulceration, inflammation, fibrosis, and spirochetes. Furthermore, Wassermann test was positive. The patient was then treated for syphilis. To our knowledge, this is the first report on FDG PET/CT in a patient suspected of having penile cancer that turned out to be syphilis. Thus, syphilis can be added to the list of benign pitfalls in FDG PET/CT....
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Superiority of 11C-Choline PET/CT in the Delineation of a Rare Intracranial Diffuse Embryonic Tumor
We report a young woman with a diffuse embryonal malignancy in the saddle area, which was depicted well by 11C-choline PET/CT, superior to 18F-FDG PET/CT and contrast-enhanced MRI. Under the guiding of 11C-choline PET/CT, the biopsy was successfully performed and the diagnosis was established. This case highlights that11C-chione PET/CT may be useful to diagnose and delineate the intracranial diffuse embryonic tumors. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
MIBG Uptake in a Gastric Gastrointestinal Stromal Tumor
MIBG scintigraphy is the imaging choice in the evaluation of pheochromocytoma and neuroblastoma. 131I-MIBG uptake by gastrointestinal stromal tumors was rare. Here we report a case in which an increased 131I-MIBG activity in an endoluminal gastric gastrointestinal stromal tumor was noted. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
18F-Fluciclovine PET/CT: A Potential Imaging Biomarker for the Evaluation of Multiple Myeloma
We present an 18F-fluciclovine PET/CT of a patient undergoing evaluation of biochemically recurrent prostate cancer with incidental radiotracer uptake within lytic osseous lesions confirmed to be multiple myeloma. We present the 18F-fluciclovine PET/CT images of an 83-year-old man with prostate cancer treated in 2005 who presented with back pain and a CT scan revealing multiple lytic osseous lesions concerning for metastases versus a plasma cell neoplasm. Prostate-specific antigen at the time of evaluation was 0.1 ng/mL. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Focal Xanthogranulomatous Pyelonephritis on FDG PET/CT
Xanthogranulomatous pyelonephritis is a rare disease that was often accompanied with urinary obstruction. The focal form of xanthogranulomatous pyelonephritis is frequently misdiagnosed as malignancy. Here we present FDG PET/CT findings of a case focal xanthogranulomatous pyelonephritis in a 66-year-old woman with polycystic liver and kidney disease. The image showed a polycystic mass in the inferior pole of right kidney with high FDG uptake in the cystic wall, which was suggestive of a cystic renal carcinoma. Right radical nephrectomy was subsequently performed. The postsurgical pathology revealed xanthogranulomatous pyel...
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Solitary Chest Wall Tuberculosis Mimicking a Malignancy Demonstrated on FDG PET/CT
Solitary chest wall tuberculosis is rare. Herein, we reported a case of image findings of chest wall tuberculosis in a 44-year-old woman. On FDG PET/CT, it presented as a solitary soft tissue mass with invasion of adjacent rib, diaphragm, and avid FDG uptake with an SUVmax of 10.19, mimicking a malignancy. The postoperative pathology supported a diagnosis of tuberculosis infection. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Unusual Presentation of Helicobacter pylori Infection as PSMA-Avid Gastric Mass
68Ga-PSMA PET/CT is one of the most common imaging uses for prostate cancer imaging. Although initially thought to be specific for prostate cancer, there are many evidences that are coming of its concentration in many other neoplastic and nonneoplastic pathologies. Helicobacter pylori is the most common bacteria causing gastric inflammation and usually presents with gastroduodenal ulcer. Here we present one unusual case of benign gastric mass formation caused by H. pylori infection with PSMA concentration. (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
18F-FDG PET/CT Metabolic Response With Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent 4/6 Kinase Inhibitors
Dysregulation of the cyclin D–CDK4/6–INK4–RB pathway, which leads to uncontrolled cell proliferation, is frequently observed in breast cancer. Recently, 3 CDK4/6 inhibitors have been FDA approved as first-line treatment for patients with hormone receptor–positive, human epidermal growth factor receptor 2–negative advanced breast cancer. Despite promising clinical results, the metabolic response to treatment with these new drugs has not been elaborately demonstrated yet. Herein, we presented a patient with hormone receptor–positive, human epidermal growth factor receptor 2–negative breast cancer who demonstrat...
Source: Clinical Nuclear Medicine - August 18, 2022 Category: Nuclear Medicine Tags: Interesting Images Source Type: research
