This Is Your Brain on Irritability
This article explains some of these research methods, providing brief summaries of what is known about brain/behavior mechanisms in disorders involving irritability, including bipolar disorder, disruptive mood dysregulation disorder, attention-deficit/hyperactivity disorder, and autism spectrum disorder. Greater access to these methods may help clinicians now and in the future, with such mechanisms translated into improved care, as occurs in the treatment of childhood leukemia (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Authors: Daniel P. Dickstein, Christine M. Barthelemy, Gracie A. Jenkins, Lena L.A. DeYoung, Anna C. Gilbert, Petya Radoeva, Kerri L. Kim, Heather A. MacPherson Source Type: research

Chronic Irritability in Youth
We describe how irritability is amenable to translational research, in part because of the relevance of frustrative nonreward, a model developed in rodents, to human irritability. Last, we demonstrate how such research has suggested a novel exposure-based intervention for irritability. (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Authors: Ellen Leibenluft, Katharina Kircanski Source Type: research

Emotion Dysregulation in Children and Adolescents: Part II
Part I of this special issue describes the many psychiatric disorders in which explosive outbursts may play an important role. Bipolar disorder, disruptive mood dysregulation disorder, oppositional defiant disorder, posttraumatic stress disorder, or mixtures of diagnoses like co-occurring attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder, or autism spectrum disorder are the conditions we describe with case examples. As we noted in Part I, none of these diagnoses are synonymous with or consistently describe the behavior itself. (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Authors: Manpreet K. Singh, Gabrielle A. Carlson Tags: Preface Source Type: research

Emotion Dysregulation and Outbursts in Children and Adolescents: Part II
CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Authors: Manpreet K. Singh, Gabrielle A. Carlson Source Type: research

Copyright
ELSEVIER (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Source Type: research

Contributors
TODD E. PETERS, MD, FAPA (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Source Type: research

Contents
Manpreet K. Singh and Gabrielle A. Carlson (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Source Type: research

Forthcoming Issues
Collaborative Partnerships to Advance Practice (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - May 28, 2021 Category: Psychiatry Source Type: research

How and Why Are Irritability and Depression Linked?
Based on its course over time, irritability is linked to depression cross-sectionally and longitudinally. Cross-sectionally, irritability takes an episodic form as a symptom in pediatric depression; yet, irritability in the absence of depressed mood or anhedonia is rare. Longitudinally, chronic irritability has been shown to predict depression rather than bipolar disorder or externalizing disorders. Evidence suggests that the link between irritability and depression is explained mostly by shared genetic risk. Both conditions are also associated with higher rates of family history of depression, childhood temperaments and p...
Source: Child and Adolescent Psychiatric Clinics of North America - March 18, 2021 Category: Psychiatry Authors: Pablo Vidal-Ribas, Argyris Stringaris Source Type: research

Dysregulation, Catastrophic Reactions, and the Anxiety Disorders
Normal developmental activities (eg, going to school, raising a hand in class, and managing typical life uncertainties) are ‘triggers’ for children and adolescents with anxiety disorders. To cope, children with anxiety avoid; however, when avoidance of developmentally appropriate activities is not possible, catastrophic responses can ensue. If these catastrophic reactions result in successful avoidance, they are like ly to recur leading to a generalized pattern of dysregulated behavior. Interventions include treating anxiety disorder symptoms to remission. For parents the goal is to challenge their child to engage in i...
Source: Child and Adolescent Psychiatric Clinics of North America - March 18, 2021 Category: Psychiatry Authors: John T. Walkup, Susan J. Friedland, Tara S. Peris, Jeffrey R. Strawn Source Type: research

Walking on Eggshells
This article examines 2 themes in my 25-year journey raising a son with severe mood dysregulation, attention deficit with hyperactivity, and learning disabilities (MAL). Raising children with MAL significantly alters parents ’ own development, having to manage their children’s chronic rages and aggression from toddlerhood through young adulthood. I propose a framework of periods parents go through, and describe a years-long progression of internal and behavioral adaptations necessary to parent these children effecti vely. The article suggests that more study is needed to understand how parents fare and what happens to ...
Source: Child and Adolescent Psychiatric Clinics of North America - March 18, 2021 Category: Psychiatry Authors: Jerry PB Source Type: research

Understanding, Assessing, and Intervening with Emotion Dysregulation in Autism Spectrum Disorder
This article provides a comprehensive review of emotion dysregulation (ED) in individuals with autism spectrum disorder (ASD). The authors describe ED from a developmental perspective, and highlight how aberrations in social development and a restricted-repetitive repertoire of behaviors, render individuals with ASD more vulnerable to ED. The article also summarizes how ED in children and adolescents with ASD has been measured and conceptualized in research and clinic settings. Evidence-based pharmacologic and cognitive behavioral interventions targeting ED in ASD are summarized, with a focus on how such approaches are tai...
Source: Child and Adolescent Psychiatric Clinics of North America - March 18, 2021 Category: Psychiatry Authors: Jennifer Keluskar, Debra Reicher, Amanda Gorecki, Carla Mazefsky, Judith A. Crowell Source Type: research

When No Diagnosis “Fits”
Clinical experience supports the concept of children with severe disturbances in most areas of functioning, with psychiatric symptom onset before age 6. They are emotionally dysregulated and extremely anxious and have developmental difficulties. Given the absence of an appropriate diagnostic category, it is best to consider clinical phenomenology and then categorize each dysfunction domain (mood/anxiety problems, possible psychosis, language impairment/thought disorder, and relationship/social problems). (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - March 18, 2021 Category: Psychiatry Authors: Deborah M. Weisbrot, Gabrielle A. Carlson Source Type: research

Emotion Dysregulation and Outbursts in Children and Adolescents: Part I
CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - March 18, 2021 Category: Psychiatry Authors: Gabrielle A. Carlson, Manpreet K. Singh Source Type: research

Copyright
ELSEVIER (Source: Child and Adolescent Psychiatric Clinics of North America)
Source: Child and Adolescent Psychiatric Clinics of North America - March 18, 2021 Category: Psychiatry Source Type: research