Weather Fluctuations May Have an Impact on Stroke Occurrence in a Society: A Population-Based Cohort Study
Conclusions: Meteorological effects on the frequency of ambulance transportation due to stroke were studied. A lower temperature and radical humidity change were identified as risk factors for ambulance transportation due to stroke, and a decrease in temperature was also associated. We speculate on the possibilities of using meteorological data to optimize the assignment of limited medical resources in medical economics.Cerebrovasc Dis Extra 2020;10:1 –10 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 5, 2020 Category: Neurology Source Type: research

Comparison of ABC Methods with Computerized Estimates of Intracerebral Hemorrhage Volume: The INTERACT2 Study
Conclusions: Overall, ABC/2 performs better than mABC/2 in estimating ICH volume. The largest discrepancies were evidenced against automated software for irregular-shaped and large ICH with SAH, but the clinical significance of this is uncertain.Cerebrovasc Dis Extra 2019;9:148 –154 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - December 13, 2019 Category: Neurology Source Type: research

Prevalence of and Risk Factors for Cerebral Microbleeds in Moyamoya Disease and Syndrome in the American Population
Conclusions: CMB are less prevalent in MMD/MMS in the USA than in Asia. An older age at diagnosis and male gender were associated with CMB. The presence of CMB was not associated with an increased risk of a subsequent ischemic or hemorrhagic stroke.Cerebrovasc Dis Extra 2019;9:139 –147 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - December 12, 2019 Category: Neurology Source Type: research

“Weekend Effect” on 30-Day Readmissions among Stroke Survivors: An Analysis of the National Readmission Database
Conclusions: We found no association between weekend admission and 30-day readmissions, providing indirect evidence of homogeneity in the quality of care delivered during week day and weekend admissions.Cerebrovasc Dis Extra 2019;9:66 –71 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - June 24, 2019 Category: Neurology Source Type: research

Microbleeds after Carotid Artery Stenting: Small Embolism May Induce Cerebral Microbleeds
Conclusions: We found that new cerebral microbleeds developed after CAS and that these might be associated with new ischemic lesions, mostly in the territory of the treated carotid artery. We speculate that these microbleeds result from the deoxygenation of hemoglobin in the embolus or, alternatively, small hemorrhagic transformation of ischemic lesions.Cerebrovasc Dis Extra 2019;9:57 –65 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - June 14, 2019 Category: Neurology Source Type: research

Stent Retriever Thrombectomy Potentially Increases the Recanalization Rate, Improves Clinical Outcome, and Decreases Mortality in Acute Basilar Occlusion: A Systematic Review and Meta-Analysis
Conclusions: The data from this meta-analysis suggest a possible superiority of SRT over IVT, pending positive results of randomized controlled trials. According to international recommendations, patients with BAO should preferentially be treated with SRT; if no contraindications exist, IVT should not be withheld.Cerebrovasc Dis Extra 2019;9:46 –56 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - June 5, 2019 Category: Neurology Source Type: research

Cardiac Magnetic Resonance Imaging in Patients with Acute Ischemic Stroke and Elevated Troponin: A TRoponin ELevation in Acute Ischemic Stroke (TRELAS) Sub-Study
Conclusions: The TRELAS sub-study indicates that noninvasive cardiac MRI may provide helpful information to identify stroke patients with or without acute coronary syndrome. Our findings might help to select stroke patients in urgent need of coronary angiography.Cerebrovasc Dis Extra 2019;9:19 –24 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 5, 2019 Category: Neurology Source Type: research

Increased Plasma VEGF Levels in Patients with Cerebral Large Artery Disease Are Associated with Cerebral Microbleeds
Conclusions: In patients with CLAD, elevated plasma VEGF might be associated with CMBs, especially those located in the cortex and/or at the gray-white junction.Cerebrovasc Dis Extra 2019;9:25 –30 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - May 5, 2019 Category: Neurology Source Type: research

Nonsteroidal Anti-Inflammatory Drugs: A Potential Pharmacological Treatment for Intracranial Aneurysm
Background: Saccular intracranial aneurysms (IAs) are outpouchings of the vessel wall of intracranial arteries. Rupture of IAs results in subarachnoid hemorrhage which is associated with high morbidity and mortality. Surgical interventions, such as clipping and coiling, have associated risks. Currently, there are no proven pharmacological treatments to prevent the growth or rupture of IAs. Infiltration of proinflammatory cytokines in response to increased wall sheer stress is a hallmark of IA. Nonsteroidal anti-inflammatory drugs (NSAIDs) are being investigated as potential therapeutic agents for reduction in growth and/or...
Source: Cerebrovascular Diseases Extra - May 5, 2019 Category: Neurology Source Type: research

Circulating Microparticles in Patients with Symptomatic Carotid Disease Are Related to Embolic Plaque Activity and Recent Cerebral Ischaemia
Conclusions: PMP and EMP were associated with stroke and recent cerebrovascular events (DWI+) but only PMP were also associated with ongoing (MES+) thrombo-embolic activity suggesting a differential biomarker potential for EMP to index cerebral ischaemia while PMP may predict on-going thrombo-embolic activity.Cerebrovasc Dis Extra 2019;9:9 –18 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - April 3, 2019 Category: Neurology Source Type: research

Health Economic Evaluations of Digital Health Interventions for Secondary Prevention in Stroke Patients: A Systematic Review
Background: In the first 5 years after their stroke, about a quarter of patients will suffer from a recurrent stroke. Digital health interventions facilitating interactions between a caregiver and a patient from a distance are a promising approach to improve patient adherence to lifestyle changes proposed by secondary prevention guidelines. Many of these interventions are not implemented in daily practice, even though efficacy has been shown. One of the reasons can be the lack of clear economic incentives for implementation. We propose to map all health economic evidence regarding digital health interventions for secondary...
Source: Cerebrovascular Diseases Extra - January 13, 2019 Category: Neurology Source Type: research

Transient Ischaemic Attack Rarely Precedes Stroke in a Cohort with Low Proportions of Large Artery Atherosclerosis: A Population-Based Study
Conclusion: In our population-based cohort, rates of TIA preceding ischaemic stroke were much lower than previously reported, probably reflective of effective secondary prevention (active TIA clinics) and primary prevention (limiting LAA prevalence). In our population, further enhancements in TIA care will be of limited yield.Cerebrovasc Dis Extra 2018;8:101 –105 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - August 23, 2018 Category: Neurology Source Type: research

A Novel Intraoperative Laser Light Imaging System to Simultaneously Visualize Visible Light and Near-Infrared Fluorescence for Indocyanine Green Videoangiography
Conclusions: Using the present setup, we can observe the color operative field and enhanced blood flow using ICG in real time. This setup could facilitate various cerebrovascular surgeries.Cerebrovasc Dis Extra 2018;8:96 –100 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - July 27, 2018 Category: Neurology Source Type: research

Effect of Exercise on Physical Recovery of People with Locked-In Syndrome after Stroke: What Do We Know from the Current Evidence? A Systematic Review
Conclusion: Studies indicate a positive trend of effect of exercise for physical recovery of people with LIS after stroke including the improvement of muscle strength, tone, walking ability, and activity in daily living. Mixed physical exercises were used. The effects were not significant. No adverse event has been reported. The quality of the existing evidence is relatively low since the papers were either case series or case studies. Further studies are needed on exercise types and dosages for better prescriptions for people with LIS after stroke. This may help to extend their lives with better control of the complicatio...
Source: Cerebrovascular Diseases Extra - July 13, 2018 Category: Neurology Source Type: research

Cerebral Haemodynamics following Acute Ischaemic Stroke: Effects of Stroke Severity and Stroke Subtype
Conclusions: AIS patients with different OCSP subtypes and severity have homogeneity in CA capability. Cerebral haemodynamic measurements in the UH were distinguishable between stroke subtype and severity, including the association between deteriorating ARI in UH with stroke severity. More studies are needed to determine their clinical significance and to understand the determinants of CA impairment in AIS patients.Cerebrovasc Dis Extra 2018;8:80 –89 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - July 11, 2018 Category: Neurology Source Type: research