Burden of Stroke in Myanmar
Myanmar is home to over 51 million people. The age- and sex-standardized mortality rate due to stroke is 165.4/100,000, while the rate of age- and sex-standardized disability-adjusted life years lost due to stroke is 2971.3/100,000. The prevalence of stroke among adults aged 40 –99 years is 1.5%. Stroke is the leading cause of morbidity and mortality and comprises 20% of the neurological workload. There are only 10 stroke units in the whole country. Doctors are aware of the importance of hypertension in stroke prevention and the need for physiotherapy after stroke, but, until recently and in rural areas, they also tend t...
Source: Cerebrovascular Diseases Extra - May 10, 2021 Category: Neurology Source Type: research
Stroke in Sri Lanka: How Can We Minimise the Burden?
The burden of stroke in Sri Lanka is high and steadily increasing. Accurate estimation of the burden is hampered by a paucity of epidemiological data. More neurologists, stroke units, facilities for modern treatments and multi-disciplinary rehabilitation services are urgently needed. Essential drugs for risk factor control and secondary prevention are available in many hospitals. Aggressive preventive strategies and promoting stroke awareness are the best ways to minimise the stroke burden in Sri Lanka.Cerebrovasc Dis Extra 2021;11:46 –48 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - April 28, 2021 Category: Neurology Source Type: research
Management of Patients with Cranial Dural Arteriovenous Fistula and Secondary Parkinson & apos;s Syndrome: Comment
Cerebrovasc Dis Extra 2021;11:45 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - April 12, 2021 Category: Neurology Source Type: research
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Cerebrovasc Dis Extra 2021;11:44 –44 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - March 26, 2021 Category: Neurology Source Type: research
Using Ultrasound and Inflammation to Improve Prediction of Ischemic Stroke: A Secondary Analysis of the Multi-Ethnic Study of Atherosclerosis
Conclusions: In a multiethnic cohort of patients without cerebrovascular disease at baseline, we found that CD, CS, and IL-6 helped predict the occurrence of primary ischemic stroke. Future research could evaluate if these basic ultrasound and serum measurements have implications for primary prevention efforts or clinical trial inclusion criteria.Cerebrovasc Dis Extra 2021;11:37 –43 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 18, 2021 Category: Neurology Source Type: research
Identification of Biomarkers in Patients with Thrombotic Thrombocytopenic Purpura Presenting with Large and Small Ischemic Stroke
Conclusions: iTTP patients can present with large ischemic strokes and are usually younger. Further research should be performed in assessing different etiologies of iTTP-associated stroke based on neutrophil extracellular trap formation biomarkers (e.g., histone markers) seen in small ischemic stroke.Cerebrovasc Dis Extra 2021;11:29 –36 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 18, 2021 Category: Neurology Source Type: research
Detection of Major Cardioembolic Sources in Real-World Patients with Ischemic Stroke or Transient Ischemic Attack of Undetermined Cause
Conclusion: Detecting a major CES is essential because appropriate treatment lowers the risk of recurrent stroke. Nonetheless, in this real-world study that aimed at routine use of TTE and ambulatory rhythm monitoring in patients with ischemic stroke or TIA of undetermined cause, the prevalence of major CES was low. Most patients with major CES on TTE already had an indication for referral to a cardiologist, suggesting that major CES might also have been identified with a much more selective use of TTE.Cerebrovasc Dis Extra 2021;11:22 –28 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 1, 2021 Category: Neurology Source Type: research
Intracerebral Hemorrhage Recurrence in Patients with and without Cerebral Amyloid Angiopathy
Conclusions: This study confirms a higher ICH recurrence risk in patients with CAA-related ICH and suggests that age, disseminated cSS, and burden of EPVS in the centrum semiovale are associated with ICH recurrence.Cerebrovasc Dis Extra 2021;11:15 –21 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 27, 2021 Category: Neurology Source Type: research
Residual Stroke Risk in Patients with Atrial Fibrillation Treated with Non-Vitamin K Oral Anticoagulants: An 8-Year Retrospective Cohort Study
Conclusions: Stroke developed in NVAF patients despite being on NOACs, with the majority being female, older, and hypertensive. Surprisingly, in general they had reasonable lipid and diabetic control.Cerebrovasc Dis Extra 2021;11:9 –14 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 18, 2021 Category: Neurology Source Type: research
Role of Favorable Perfusion Imaging in Predicting the Outcome of Patients with Acute Ischemic Stroke due to Large Vessel Occlusion Undergoing Effective Thrombectomy: A Single-Center Study
Conclusions: In our small-sized and retrospective study, the presence of ischemic penumbra was associated with a better clinical outcome in patients with AIS due to LVO after MT. In the future, a larger and controlled study with similar criteria of enrollment is needed to further validate the role of CTP in patient selection for MT, regardless of the time from the onset of symptoms.Cerebrovasc Dis Extra 2021;11:1 –8 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 15, 2021 Category: Neurology Source Type: research
Red Blood Cell Distribution Width as a 5-Year Prognostic Marker in Patients Submitted to Carotid Endarterectomy
Conclusion: RDW is a widely available and low-cost marker that independently predicts long-term mortality, MACE, and MI after CEA. This biomarker could prove useful in assessing which patients would likely benefit from CEA in the long term.Cerebrovasc Dis Extra 2020;10:181 –192 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - December 16, 2020 Category: Neurology Source Type: research
High Prevalence of Deep Venous Thrombosis in Non-Severe COVID-19 Patients Hospitalized for a Neurovascular Disease
Conclusion: Despite thromboprophylaxis, systematic bedside DUS showed a high prevalence (38.5%) of asymptomatic DVT in non-severe COVID-19 patients suffering from a neurovascular disease. In the absence of a reliable marker of DVT, we suggest that this non-invasive investigation could be an interesting tool to monitor peripheral venous thrombotic complications in such patients.Cerebrovasc Dis Extra 2020;10:174 –180 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - December 7, 2020 Category: Neurology Source Type: research
Use of the Cardiovascular Polypill in Secondary Prevention of Cerebrovascular Disease: A Real-Life Tertiary Hospital Cohort Study of 104 Patients
Conclusion: In our experience, the cardiovascular polypill achieved a higher reduction in SBP levels and was well tolerated. Adherence was similar to that found in the previous literature, which is remarkable given the real-life setting of our study.Cerebrovasc Dis Extra 2020;10:166 –173 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - November 11, 2020 Category: Neurology Source Type: research
Impact of a Stay-at-Home Order on Stroke Admission, Subtype, and Metrics during the COVID-19 Pandemic
Conclusions: There was a trend of decreasing AIS admissions during the COVID-19 pandemic. There was also a significantly increased number of AIS patients with LVO who received MT, especially those with COVID-19. We conclude that cytokine storm resulting from SARS-CoV-2 infection might play a role in AIS patients with COVID-19.Cerebrovasc Dis Extra 2020;10:159 –165 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - November 9, 2020 Category: Neurology Source Type: research
Treatment with Delipid Extracorporeal Lipoprotein Filter from Plasma after Intravenous Thrombolysis for Acute Ischemic Stroke: A Single-Center Experience
Conclusions: DELP following intravenous thrombolysis should be safe, and is associated with neurological function improvement, possibly through multiple neuroprotective mechanisms. Prospective trials are needed.Cerebrovasc Dis Extra 2020;10:148 –158 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 22, 2020 Category: Neurology Source Type: research
