High Risk of Seizures and Epilepsy after Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Stroke 

Conclusion: The incidence of seizures and epilepsy after malignant MCA infarcts submitted to DHC might be very high. Seizure might occur precociously in patients who are not submitted to anticonvulsant prophylaxis. The large stroke volume and the large cortical ischemic area seem to be the main risk factors for seizure or epilepsy development in this subtype of stroke. 
Cerebrovasc Dis Extra 2017;7:51 –61 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - March 30, 2017 Category: Neurology Source Type: research

Measurement of Oxygen Desaturation Is Not Useful for the Detection of Aspiration in Dysphagic Stroke Patients
Conclusions: According to this study, measurement of oxygen desaturation is not a suitable screening tool for the detection of aspiration in stroke patients.Cerebrovasc Dis Extra 2017;7:44-50 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - March 3, 2017 Category: Neurology Source Type: research

Brain Natriuretic Peptide Is a Powerful Predictor of Outcome in Stroke Patients with Atrial Fibrillation 

Conclusions: Apart from NIHSS score, BNP was a very useful predictor for long-term outcomes of patients with NVAF after AIS. 
Cerebrovasc Dis Extra 2017;7:35 –43 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - March 2, 2017 Category: Neurology Source Type: research

MRI-Based Neuroanatomical Predictors of Dysphagia, Dysarthria, and Aphasia in Patients with First Acute Ischemic Stroke 

Conclusion: Predicting outcomes following acute stroke is important for treatment decisions. Determining the risk of major post-stroke impairments requires consideration of factors beyond lesion localization. Accordingly, we demonstrated interactions between localized and global brain function for dysphagia and elucidated common lesion locations across 3 debilitating impairments. 
Cerebrovasc Dis Extra 2017;7:21 –34 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 16, 2017 Category: Neurology Source Type: research

The Course and Impact of Poststroke Insomnia in Stroke Survivors Aged 18 to 65 Years: Results from the Psychosocial Outcomes In StrokE (POISE) Study 

Conclusions: Chronic insomnia has a negative effect on disability and return to work 1 year after stroke even after adjusting for demographic, psychiatric, and disability factors. Identifying and appropriately targeting insomnia through known effective treatments may improve functional outcomes after stroke. 
Cerebrovasc Dis Extra 2017;7:9 –20 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - February 3, 2017 Category: Neurology Source Type: research

The Role of White Matter Damage in the Risk of Periprocedural Diffusion-Weighted Lesions after Carotid Artery Stenting
Conclusions: Treated side and preexisting white matter damage are risk conditions for brain microembolism during CAS. This should be taken into account to optimize severe carotid artery disease management.Cerebrovasc Dis Extra 2017;7:1-8 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - January 26, 2017 Category: Neurology Source Type: research

Low Incidence of Atrial Fibrillation in Patients with Transient Ischemic Attack
Conclusion: In this retrospective study, patients with TIA had a low incidence of AF detected with ECG and 72-hour Holter monitoring. Prospective studies are needed to confirm these findings.Cerebrovasc Dis Extra 2016;6:140-149 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - November 29, 2016 Category: Neurology Source Type: research

Risk Factors for Incident Carotid Artery Revascularization among Older Adults: The Cardiovascular Health Study
Conclusions: Even after accounting for carotid stenosis and incident cerebral ischemic events, carotid revascularization is related to age, gender, and cardiovascular risk factors. Further study of these demographic disparities and the role of risk factor control is warranted.Cerebrovasc Dis Extra 2016;6:129-139 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - November 15, 2016 Category: Neurology Source Type: research

How Reliable Are Administrative Data for Capturing Stroke Patients and Their Care
Conclusions: Inpatient and ED administrative data were found to be reliable in the reporting of the International Classification of Diagnosis, 10th revision, Canada (ICD-10-CA)-coded ischemic stroke, ICH and TIA, and for the recording of atrial fibrillation and diabetes. The combination of physician billing data with hospital administrative data greatly improved the capture of some diagnostic services provided to inpatients.Cerebrovasc Dis Extra 2016;6:96-106 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 18, 2016 Category: Neurology Source Type: research

Paracrine Mechanisms of Intravenous Bone Marrow-Derived Mononuclear Stem Cells in Chronic Ischemic Stroke
Conclusion: Autologous mononuclear stem cell infusion is safe and tolerable by chronic ischemic stroke patients. The released growth factors (VEGF and BDNF) in the microenvironment could be due to the paracrine hypothesis of stem cell niche and neurorehabilitation regime.Cerebrovasc Dis Extra 2016;6:107-119 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 18, 2016 Category: Neurology Source Type: research

How Reliable Are Administrative Data for Capturing Stroke Patients and Their Care?
Conclusions: Inpatient and ED administrative data were found to be reliable in the reporting of the International Classification of Diagnosis, 10th revision, Canada (ICD-10-CA)-coded ischemic stroke, ICH and TIA, and for the recording of atrial fibrillation and diabetes. The combination of physician billing data with hospital administrative data greatly improved the capture of some diagnostic services provided to inpatients.Cerebrovasc Dis Extra 2016;6:96-106 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 17, 2016 Category: Neurology Source Type: research

Ultra-Early Combination Antiplatelet Therapy with Cilostazol for the Prevention of Branch Atheromatous Disease: A Multicenter Prospective Study
Conclusions: Our trial showed that clinical progression of BAD was significantly reduced with the administration of ultra-early aggressive combination therapy using cilostazol compared to treatment with antiplatelet monotherapy.Cerebrovasc Dis Extra 2016;6:84-95 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - October 11, 2016 Category: Neurology Source Type: research

High ABCD2 Scores and In-Hospital Interventions following Transient Ischemic Attack
Background and Purpose: Following transient ischemic attack (TIA), there is increased risk for ischemic stroke. The American Heart Association recommends admission of patients with ABCD2 scores ≥3 for observation, rapid performance of diagnostic tests, and potential acute intervention. We aimed to determine if there is a relationship between ABCD2 scores, in-hospital ischemic events, and in-hospital treatments after TIA admission.Methods: We reviewed consecutive patients admitted between 2006 and 2011 following a TIA, defined as transient focal neurological symptoms attributed to a specific vascular distribution and last...
Source: Cerebrovascular Diseases Extra - October 11, 2016 Category: Neurology Source Type: research

Early Blood Pressure Lowering Does Not Reduce Growth of Intraventricular Hemorrhage following Acute Intracerebral Hemorrhage: Results of the INTERACT Studies
Background: Intraventricular hemorrhage (IVH) extension is common following acute intracerebral hemorrhage (ICH) and is associated with poor prognosis.Aim: To determine whether intensive blood pressure (BP)-lowering therapy reduces IVH growth.Methods: Pooled analyses of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials (INTERACT1 and INTERACT2) computed tomography (CT) substudies; multicenter, open, controlled, randomized trials of patients with acute spontaneous ICH and elevated systolic BP, randomly assigned to intensive ( (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - September 7, 2016 Category: Neurology Source Type: research

Clinical Characteristics of Cerebrovascular Pathology with Patients Suffering from Ph-Negative Myeloproliferative Disease
Conclusion: Patients suffering from MPD had asymptomatic focal changes in the brain in the absence of concomitant vascular disease (hypertension, atherosclerotic vascular disease, heart rhythm disorders) in 50% of cases. MPD, while remaining un- or underdiagnosed, presents a major concern in the cerebrovascular setting. A large number of thrombotic strokes occurring in patients with ET underline the necessity of early diagnostics and preventive therapy in these patients.Cerebrovasc Dis Extra 2016;6:66-70 (Source: Cerebrovascular Diseases Extra)
Source: Cerebrovascular Diseases Extra - September 6, 2016 Category: Neurology Source Type: research