Downregulation of GDF15 suppresses ferroptosis and predicts unfavorable prognosis in clear cell renal cell carcinoma
Growth differentiation factor 15 (GDF15), a member of the transforming growth factor beta (TGF- β) superfamily, is involved in various pathophysiological processes such as anorexia, obesity, inflammation, and t... (Source: Cell Division)
Source: Cell Division - December 11, 2023 Category: Cytology Authors: Dongliang Yang, Zhongyin He, Jiawei Lu, Xiaolin Yuan, Haiyong Liu, Yagang Xue, Ting Chen and Hongxing Gu Tags: Research Source Type: research
Exosome-transmitted miR-30a-5p enhances cell proliferation, migration, and invasion in ovarian cancer
Ovarian cancer (OC) causes the highest rates of mortality among women ’s genital tract malignancies. Micro-ribonucleic acid (miRNA), the most abundant long noncoding RNAs transmitted by exosomes, has been revea... (Source: Cell Division)
Source: Cell Division - November 1, 2023 Category: Cytology Authors: Jian Cao, Huan Wang, Jing Yang, Jing Zhang, Dake Li and Pengfei Xu Tags: Research Source Type: research
Angelica acutiloba Kitagawa flower induces A549 cell pyroptosis via the NF- κB/NLRP3 pathway for anti-lung cancer effects
In this study, we investigated the anti-lung cancer effects of two compound... (Source: Cell Division)
Source: Cell Division - November 1, 2023 Category: Cytology Authors: Yonghu Chen, Fangying Zhu, Xianhua Che, Yanwei Li, Ning Li, Zhe Jiang and Xuezheng Li Tags: Research Source Type: research
Polyploid cell dynamics and death before and after PEG-treatment of a NIH/3T3 derived culture: vinblastine effects on the regulation of cell subpopulations heterogeneity
Neoplastic subpopulations can include polyploid cells that can be involved in tumor evolution and recurrence. Their origin can be traced back to the tumor microenvironment or chemotherapeutic treatment, which ... (Source: Cell Division)
Source: Cell Division - October 30, 2023 Category: Cytology Authors: Alessandra Spano and Luigi Sciola Tags: Research Source Type: research
Preeclampsia-associated lncRNA FEZF1-AS1 regulates cell proliferation and apoptosis in placental trophoblast cells through the ELAVL1/NOC2L axis
LncRNAs have been shown to be involved in and control the biological processes of multiple diseases, including preeclampsia (PE). The impairment of trophoblast cell proliferation is recognized as a significant... (Source: Cell Division)
Source: Cell Division - October 23, 2023 Category: Cytology Authors: Xudong Zhao, Fengyun Su, Qing Guo, Xiuhong Tao, Huifeng Wang, Hongling Wang, Qinwen Li and Wangmeng Zhang Tags: Research Source Type: research
Slik maintains tissue homeostasis by preventing JNK-mediated apoptosis
In this study, we have characterized the Drosophila Ste20-... (Source: Cell Division)
Source: Cell Division - October 4, 2023 Category: Cytology Authors: Chenglin Li, Xiaojie Zhu, Xinyue Sun, Xiaowei Guo, Wenzhe Li, Ping Chen, Yulii V. Shidlovskii, Qian Zhou and Lei Xue Tags: Research Source Type: research
Kynureninase knockdown inhibits cisplatin resistance in vivo and in vitro and impacts the prognosis of cervical adenocarcinoma
Chemotherapy resistance is a leading cause of treatment failure in cases of cervical adenocarcinoma (ADC), and no effective treatment approach has yet been found. We previously identified the differentially ex... (Source: Cell Division)
Source: Cell Division - September 24, 2023 Category: Cytology Authors: Jun-wen Zhang, Ya-nan Wang, Mei-ling Zhong and Mei-rong Liang Tags: Research Source Type: research
Rapid and accurate genotyping of human SNP rs671 in aldehyde dehydrogenase 2 gene using one-step CRISPR/Cas12b assay without DNA amplification
The SNP rs671 of Human aldehyde dehydrogenase (ALDH) is G-A transition at 1510th nucleotides, which is an important clinical indicator of alcoholic liver disease, digestive tract cancer and some drug efficienc... (Source: Cell Division)
Source: Cell Division - August 28, 2023 Category: Cytology Authors: Fang Wu, Yong Xue, Yan Wang, Xinxin Si, Xinyue Zhang, Yuyang Xu and Zhidan Luo Tags: Brief Report Source Type: research
The roles of METTL3 on autophagy and proliferation of vascular smooth muscle cells are mediated by mTOR rather than by CDK1
Aberrant proliferation of vascular smooth muscle cells (VSMCs) is the cause of neointima formation followed by vascular injury. Autophagy is involved in this pathological process, but its function is controver... (Source: Cell Division)
Source: Cell Division - August 9, 2023 Category: Cytology Authors: Hanshen Luo, Xingliang Wu, Bo Huo, Liyuan Liu, Ding-Sheng Jiang and Xin Yi Tags: Research Source Type: research
Expression of genes regulating cell division in porcine follicular granulosa cells
Cell cycle regulation influences the proliferation of granulosa cells and affects many processes related to ovarian folliclular growth and ovulation. Abnormal regulation of the cell cycle can lead to many dise... (Source: Cell Division)
Source: Cell Division - August 7, 2023 Category: Cytology Authors: Jakub Kulus, Wies ława Kranc, Magdalena Kulus, Piotr Dzięgiel, Dorota Bukowska, Paul Mozdziak, Bartosz Kempisty and Paweł Antosik Tags: Research Source Type: research
Role of microRNAs in regulation of doxorubicin and paclitaxel responses in lung tumor cells
Lung cancer as the leading cause of cancer related mortality is always one of the main global health challenges. Despite the recent progresses in therapeutic methods, the mortality rate is still significantly ... (Source: Cell Division)
Source: Cell Division - July 21, 2023 Category: Cytology Authors: Amirhosein Maharati and Meysam Moghbeli Tags: Review Source Type: research
Development and validation of a two glycolysis-related LncRNAs prognostic signature for glioma and in vitro analyses
This study aimed to investigate the progn... (Source: Cell Division)
Source: Cell Division - June 24, 2023 Category: Cytology Authors: Xiaoping Xu, Shijun Zhou, Yuchuan Tao, Zhenglan Zhong, Yongxiang Shao and Yong Yi Tags: Research Source Type: research
SIRT4 is an independent prognostic factor in bladder cancer and inhibits bladder cancer growth by suppressing autophagy
Nucleosome-localized sirtuin 4 (SIRT4) was found to function as an oncogene and tumor suppressor gene in different tumors. However, the clinical significance of SIRT4 in bladder urothelial carcinoma (BLCA) has... (Source: Cell Division)
Source: Cell Division - June 10, 2023 Category: Cytology Authors: Jie Yin, Guohao Cai, Huaiwen Wang, Weijia Chen, Shan Liu and Guoyu Huang Tags: Research Source Type: research
Molecular mechanisms involved in regulating protein activity and biological function of MST3
Mammalian sterile 20-like (Ste20-like) protein kinase 3 (MST3) or serine/threonine-protein kinase 24 (STK24) is a serine/threonine protein kinase that belongs to the mammalian STE20-like protein kinase family.... (Source: Cell Division)
Source: Cell Division - May 18, 2023 Category: Cytology Authors: Jing Qiu, Junzhi Xiong, Lu Jiang, Xinmin Wang, Kebin Zhang and Hua Yu Tags: Review Source Type: research
circRNA_0001006 predicts prognosis and regulates cellular processes of triple-negative breast cancer via miR-424-5p
circular RNAs (circRNAs) have been considered novel biomarker candidates for human cancers, such as triple-negative breast cancer (TNBC). circ_0001006 was identified as a differentially expressed circRNA in me... (Source: Cell Division)
Source: Cell Division - May 16, 2023 Category: Cytology Authors: Jiaqi Liu, Linna Kong, Wenqing Bian, Xiaona Lin, Feifei Wei and Jun Chu Tags: Research Source Type: research
