A review study on green synthesis of chitosan derived schiff bases and their applications
Carbohydr Res. 2023 Dec 5;535:109002. doi: 10.1016/j.carres.2023.109002. Online ahead of print.ABSTRACTChitosan is a bio-degradable, bio-compatible, non-toxic, and renewable biopolymer. The reactive amino group of chitosan has gained importance because using these amino groups can help achieve the different types of structural modification in chitosan. Chemical modification of chitosan via imine functionalization results in the formation of a chitosan Schiff base. The present review covers the green synthesis of chitosan Schiff bases using non-conventional green methods such as microwave irradiation, green solvent, ultraso...
Source: Carbohydrate Research - December 8, 2023 Category: Genetics & Stem Cells Authors: Shazia Hussain Shiwani Berry Source Type: research
Isomerization and epimerization of fructose in phosphate buffer under subcritical water conditions
Carbohydr Res. 2023 Dec 2;535:109003. doi: 10.1016/j.carres.2023.109003. Online ahead of print.ABSTRACTIsomerization and epimerization of fructose to glucose, mannose, allulose, and allose were executed using a subcritical phosphate buffer solution to effectively produce useful monosaccharides. The conversion of the substrate and the yield of products were dependent on the reaction temperature, initial pH, initial substrate concentration, and buffer concentration. A high yield of mannose was achieved under the optimal reaction conditions we identified. We subsequently performed the kinetic analysis based on the proposed re...
Source: Carbohydrate Research - December 6, 2023 Category: Genetics & Stem Cells Authors: Kenta Hashimoto Tsugumi Niina Takashi Kobayashi Shuji Adachi Yoshiyuki Watanabe Source Type: research
Structural and functional characterization of exopolysaccharide from Leuconostoc citreum BH10 discovered in birch sap
In this study, Leuconostoc citreum BH10, an endophytic strain, was isolated from aseptically collected xylem sap of birch for the first time, and its exopolysaccharide (LCEPS) production was up to 46.31 g/L in glucan producing medium. The produced LCEPS was purified to obtain two water-soluble fractions, named as LCEPS-1 and LCEPS-2, respectively. The major fraction LCEPS-1 was characterized to be comprised of glucose with average molecular weight of 6.34 × 106 Da. The structure of LCEPS-1 was investigated by spectroscopy analysis, which revealed that LCEPS-1 was identified with containing 90.45 % α-(1,6) linkages in the...
Source: Carbohydrate Research - December 6, 2023 Category: Genetics & Stem Cells Authors: Zhiwen Ge Dan Wang Wenting Zhao Pan Wang Yiqiang Dai Mingsheng Dong Junjuan Wang Yuanyuan Zhao Xiaoyan Zhao Source Type: research
Isomerization and epimerization of fructose in phosphate buffer under subcritical water conditions
Carbohydr Res. 2023 Dec 2;535:109003. doi: 10.1016/j.carres.2023.109003. Online ahead of print.ABSTRACTIsomerization and epimerization of fructose to glucose, mannose, allulose, and allose were executed using a subcritical phosphate buffer solution to effectively produce useful monosaccharides. The conversion of the substrate and the yield of products were dependent on the reaction temperature, initial pH, initial substrate concentration, and buffer concentration. A high yield of mannose was achieved under the optimal reaction conditions we identified. We subsequently performed the kinetic analysis based on the proposed re...
Source: Carbohydrate Research - December 6, 2023 Category: Genetics & Stem Cells Authors: Kenta Hashimoto Tsugumi Niina Takashi Kobayashi Shuji Adachi Yoshiyuki Watanabe Source Type: research
Structural and functional characterization of exopolysaccharide from Leuconostoc citreum BH10 discovered in birch sap
In this study, Leuconostoc citreum BH10, an endophytic strain, was isolated from aseptically collected xylem sap of birch for the first time, and its exopolysaccharide (LCEPS) production was up to 46.31 g/L in glucan producing medium. The produced LCEPS was purified to obtain two water-soluble fractions, named as LCEPS-1 and LCEPS-2, respectively. The major fraction LCEPS-1 was characterized to be comprised of glucose with average molecular weight of 6.34 × 106 Da. The structure of LCEPS-1 was investigated by spectroscopy analysis, which revealed that LCEPS-1 was identified with containing 90.45 % α-(1,6) linkages in the...
Source: Carbohydrate Research - December 6, 2023 Category: Genetics & Stem Cells Authors: Zhiwen Ge Dan Wang Wenting Zhao Pan Wang Yiqiang Dai Mingsheng Dong Junjuan Wang Yuanyuan Zhao Xiaoyan Zhao Source Type: research
Xylarcurcosides A-C, three novel isopimarane-type diterpene glycosides from Xylaria curta YSJ-5
Carbohydr Res. 2023 Nov 23;535:108987. doi: 10.1016/j.carres.2023.108987. Online ahead of print.ABSTRACTThree previously undescribed isopimarane-type diterpene glycosides named as xylarcurcosides A-C (1-3) along with two known ones 16-α-d-mannopyranosyloxyisopimar-7-en-19-oic acid (4) and hypoxylonoid A (5) were successfully isolated from an ethyl acetate extract of the endophytic fungus Xylaria curta YSJ-5 growing in leaves of Alpinia zerumbet. The spectroscopic methods, electronic circular dichroism (ECD) calculations, and X-ray diffraction experiments were conducted to identify their absolute chemical structures. All t...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Shanshan Wei Chen Chen Jiaying Lai Yanjiang Zhang Xinmiao Nong Fangfang Duan Ping Wu Sasa Wang Haibo Tan Source Type: research
Isolation and structural characterization of eight new resin glycosides, calyhedins XVI-XXIII, from the rhizomes of Calystegia hederacea
In this study, eight new resin glycosides, termed calyhedins XVI (1)-XXIII (8), were isolated from the rhizomes of C. hederacea. Compounds 1-8 are penta- or hexa-glycosides with macrolactone structures, and their sugar moieties are partially acylated by five organic acids, including 2S-methylbutyric, (E)-2-methylbut-2-enoic, and 2R-methyl-3R-hydroxybutyric acids. Compounds 1-5 are the first identified macrocyclic resin glycosides with five monosaccharides obtained from this plant, and 2 and 4 are the first to be characterized as containing calyhedic acid A as the glycosidic acid component. Compounds 1-8 were of the four fo...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Masateru Ono Ryota Arakawa Hirotaka Nishikawa Nodoka Misuda Shin Yasuda Hitoshi Yoshimitsu Ryota Tsuchihasi Masafumi Okawa Junei Kinjo Source Type: research
Convergent synthesis of a hexadecavalent heterobifunctional ABO blood group glycoconjugate
Carbohydr Res. 2023 Nov 23;535:108988. doi: 10.1016/j.carres.2023.108988. Online ahead of print.ABSTRACTNaturally occurring glycans are often found in a multivalent presentation. Cell surface receptors that recognize these displays may form clusters, which can lead to signalling or endocytosis. One of the challenges in generating synthetic displays of multivalent carbohydrates is providing high valency as well as access to heterofunctional conjugates to allow attachment of multiple antigens or payloads. We designed a strategy based on a set of bifunctional linkers to generate a heterobifunctional multivalent display of two...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Gour Chand Daskhan Hanh-Thuc Ton Tran Christopher W Cairo Source Type: research
Xylarcurcosides A-C, three novel isopimarane-type diterpene glycosides from Xylaria curta YSJ-5
Carbohydr Res. 2023 Nov 23;535:108987. doi: 10.1016/j.carres.2023.108987. Online ahead of print.ABSTRACTThree previously undescribed isopimarane-type diterpene glycosides named as xylarcurcosides A-C (1-3) along with two known ones 16-α-d-mannopyranosyloxyisopimar-7-en-19-oic acid (4) and hypoxylonoid A (5) were successfully isolated from an ethyl acetate extract of the endophytic fungus Xylaria curta YSJ-5 growing in leaves of Alpinia zerumbet. The spectroscopic methods, electronic circular dichroism (ECD) calculations, and X-ray diffraction experiments were conducted to identify their absolute chemical structures. All t...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Shanshan Wei Chen Chen Jiaying Lai Yanjiang Zhang Xinmiao Nong Fangfang Duan Ping Wu Sasa Wang Haibo Tan Source Type: research
Isolation and structural characterization of eight new resin glycosides, calyhedins XVI-XXIII, from the rhizomes of Calystegia hederacea
In this study, eight new resin glycosides, termed calyhedins XVI (1)-XXIII (8), were isolated from the rhizomes of C. hederacea. Compounds 1-8 are penta- or hexa-glycosides with macrolactone structures, and their sugar moieties are partially acylated by five organic acids, including 2S-methylbutyric, (E)-2-methylbut-2-enoic, and 2R-methyl-3R-hydroxybutyric acids. Compounds 1-5 are the first identified macrocyclic resin glycosides with five monosaccharides obtained from this plant, and 2 and 4 are the first to be characterized as containing calyhedic acid A as the glycosidic acid component. Compounds 1-8 were of the four fo...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Masateru Ono Ryota Arakawa Hirotaka Nishikawa Nodoka Misuda Shin Yasuda Hitoshi Yoshimitsu Ryota Tsuchihasi Masafumi Okawa Junei Kinjo Source Type: research
Convergent synthesis of a hexadecavalent heterobifunctional ABO blood group glycoconjugate
Carbohydr Res. 2023 Nov 23;535:108988. doi: 10.1016/j.carres.2023.108988. Online ahead of print.ABSTRACTNaturally occurring glycans are often found in a multivalent presentation. Cell surface receptors that recognize these displays may form clusters, which can lead to signalling or endocytosis. One of the challenges in generating synthetic displays of multivalent carbohydrates is providing high valency as well as access to heterofunctional conjugates to allow attachment of multiple antigens or payloads. We designed a strategy based on a set of bifunctional linkers to generate a heterobifunctional multivalent display of two...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Gour Chand Daskhan Hanh-Thuc Ton Tran Christopher W Cairo Source Type: research
Xylarcurcosides A-C, three novel isopimarane-type diterpene glycosides from Xylaria curta YSJ-5
Carbohydr Res. 2023 Nov 23;535:108987. doi: 10.1016/j.carres.2023.108987. Online ahead of print.ABSTRACTThree previously undescribed isopimarane-type diterpene glycosides named as xylarcurcosides A-C (1-3) along with two known ones 16-α-d-mannopyranosyloxyisopimar-7-en-19-oic acid (4) and hypoxylonoid A (5) were successfully isolated from an ethyl acetate extract of the endophytic fungus Xylaria curta YSJ-5 growing in leaves of Alpinia zerumbet. The spectroscopic methods, electronic circular dichroism (ECD) calculations, and X-ray diffraction experiments were conducted to identify their absolute chemical structures. All t...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Shanshan Wei Chen Chen Jiaying Lai Yanjiang Zhang Xinmiao Nong Fangfang Duan Ping Wu Sasa Wang Haibo Tan Source Type: research
Isolation and structural characterization of eight new resin glycosides, calyhedins XVI-XXIII, from the rhizomes of Calystegia hederacea
In this study, eight new resin glycosides, termed calyhedins XVI (1)-XXIII (8), were isolated from the rhizomes of C. hederacea. Compounds 1-8 are penta- or hexa-glycosides with macrolactone structures, and their sugar moieties are partially acylated by five organic acids, including 2S-methylbutyric, (E)-2-methylbut-2-enoic, and 2R-methyl-3R-hydroxybutyric acids. Compounds 1-5 are the first identified macrocyclic resin glycosides with five monosaccharides obtained from this plant, and 2 and 4 are the first to be characterized as containing calyhedic acid A as the glycosidic acid component. Compounds 1-8 were of the four fo...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Masateru Ono Ryota Arakawa Hirotaka Nishikawa Nodoka Misuda Shin Yasuda Hitoshi Yoshimitsu Ryota Tsuchihasi Masafumi Okawa Junei Kinjo Source Type: research
Convergent synthesis of a hexadecavalent heterobifunctional ABO blood group glycoconjugate
Carbohydr Res. 2023 Nov 23;535:108988. doi: 10.1016/j.carres.2023.108988. Online ahead of print.ABSTRACTNaturally occurring glycans are often found in a multivalent presentation. Cell surface receptors that recognize these displays may form clusters, which can lead to signalling or endocytosis. One of the challenges in generating synthetic displays of multivalent carbohydrates is providing high valency as well as access to heterofunctional conjugates to allow attachment of multiple antigens or payloads. We designed a strategy based on a set of bifunctional linkers to generate a heterobifunctional multivalent display of two...
Source: Carbohydrate Research - December 4, 2023 Category: Genetics & Stem Cells Authors: Gour Chand Daskhan Hanh-Thuc Ton Tran Christopher W Cairo Source Type: research
Molecular weight-dependent antitumor effects of prunes-derived type I arabinogalactan on human and murine triple wild-type melanomas
Carbohydr Res. 2023 Nov 22;535:108986. doi: 10.1016/j.carres.2023.108986. Online ahead of print.ABSTRACTThe regulation of metastasis-related cellular aspects of two structurally similar AGIs from prunes tea infusion, with different molar masses, was studied in vitro against Triple Wild-Type metastatic melanoma (TWM) from murine and human origin. The higher molar mass AGI (AGI-78KDa) induced TWMs cells death and, in murine cell line, it decreased some metastasis-related cellular processes: invasiveness capacity, cell-extracellular matrix interaction, and colonies sizes. The lower molar mass AGI (AGI-12KDa) did not induce ce...
Source: Carbohydrate Research - December 2, 2023 Category: Genetics & Stem Cells Authors: Keila Taiana Vaz da Luz Jenifer Pendiuk Gon çalves Daniel de Lima Bellan Bruna Renata Caitano Visnheski Vanessa Suzane Schneider Lucimara Mach Cortes Cordeiro Jos é Eduardo Vargas Renato Puga Edvaldo da Silva Trindade Carolina Camargo de Oliveira Fernan Source Type: research
