Supplements for cognitive ability in patients with mild cognitive impairment or Alzheimers disease: a protocol for systematic review and network meta-analysis of randomised controlled trials
This study is scheduled to commence on 1 June 2023 and conclude on 1 October 2023.
Ethics and dissemination
Ethics approval is not required for systematic review and network meta-analysis. The results will be submitted to a peer-reviewed journal or at a conference.
Trial registration number
PROSPERO (CRD42023414700). (Source: BMJ Open)
Source: BMJ Open - April 2, 2024 Category: General Medicine Authors: Zhang, X.-Y., Li, Y.-Q., Yin, Z.-H., Bao, Q.-N., Xia, M.-Z., Chen, Z.-H., Zhong, W.-Q., Wu, K.-X., Yao, J., Liang, F.-R. Tags: Open access, Neurology Source Type: research
Willingness of healthcare providers to perform population-based cancer screening: a cross-sectional study in primary healthcare institutions in Tianjin, China
Conclusions
In China, healthcare providers with a positive attitude towards screening have a stronger willingness to contribute to cancer screening, and therefore healthcare providers’ attitude, recognition of the importance of screening and acceptable workload should be optimised to improve the uptake of cancer screening. (Source: BMJ Open)
Source: BMJ Open - April 2, 2024 Category: General Medicine Authors: Zheng, S., Zhang, X., Greuter, M. J. W., de Bock, G. H., Lu, W. Tags: Open access, Public health Source Type: research
Association of prepregnancy body mass index and gestational weight gain trajectory with adverse pregnancy outcomes--a prospective cohort study in Shanghai
Conclusions
As independent risk factors, excessively high and low prepregnancy BMI and GWG can increase the risk of APOs. (Source: BMJ Open)
Source: BMJ Open - April 2, 2024 Category: General Medicine Authors: Ma, Z., Chu, L., Zhang, Z., Hu, Y., Zhu, Y., Wu, F., Zhang, Y. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research
Assessment of rehabilitation following acute ischaemic stroke in China: a registry-based retrospective observational study
Conclusions
Nearly one-quarter of patients who had an AIS do not undergo documented rehabilitation assessment and compliance across hospitals varies. Thus, it is necessary to improve adherence to rehabilitation assessment to improve the quality of medical care for patients who had an AIS. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Yin, Z., Deng, Y., Li, Z., Gu, H., Zhou, Q., Wang, Y., Wang, C., on behalf of Chinese Stroke Center Alliance Investigators Tags: Open access, Evidence based practice Source Type: research
Role of vitamin C in treatment of community-acquired pneumonia in adult patients requiring hospitalisation: a systematic review protocol
Introduction
Community-acquired pneumonia (CAP) is a leading cause of hospitalisation and is associated with a high mortality. Vitamin C is a powerful antioxidant and has been used in treatment of infections; however, its role as an adjunctive treatment in CAP is unclear. This review aims to assess the efficacy and safety of vitamin C in adults who require hospitalisation for CAP.
Methods and analyses
Searches will be conducted from inception to November 2023 on Ovid MEDLINE Daily and MEDLINE, Embase CINAHL, the Cochrane Central Register of Controlled Trials, Scopus, Web of Science and ClinicalTrials.gov databases with th...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Sharma, Y., Sumanadasa, S., Shahi, R., Thompson, C. Tags: Open access, Infectious diseases Source Type: research
Midwives experience of telehealth and remote care: a systematic mixed methods review
Conclusions
Most current studies suggest that midwives’ experience of telehealth is deeply intertwined with midwives’ experience of the response to COVID-19 pandemic in general. More research is needed to understand how sustained use of telehealth or newer hybrid models of telehealth and in-person care are perceived by midwives. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Golden, B. N., Elrefaay, S., McLemore, M. R., Alspaugh, A., Baltzell, K., Franck, L. S. Tags: Open access, Nursing Source Type: research
Maternal outcomes of pre-eclampsia with severe features and its determinants at Abebech Gobena Mothers and Childrens Health and Saint Peters Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
Conclusions
The prevalence of unfavourable maternal outcomes was high compared with other studies in Ethiopia. Maternal age, residence, occupation, blood pressure on admission and severe headache have shown a statistically significant association with unfavourable maternal outcomes. Socioeconomic development and early identification of severe signs and symptoms of pre-eclampsia are needed to reduce unfavourable outcomes. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Tadese, M., Damesa, W. A., Solomon, G. S., Wakie, G. E., Tessema, S. D., Endale, A. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research
Effectiveness of web-based interventions for women with urinary incontinence: protocol for a systematic review and meta-analysis of randomised controlled trials
Introduction
Urinary incontinence (UI) is one of the most common chronic diseases among women, which can endanger their physical and mental health and incur a heavy financial burden on both individuals and society. Web-based interventions (WBIs) have been applied to manage women’s UI, but their effectiveness has remained inconclusive. This systematic review and meta-analysis aims to explore the effectiveness of WBIs on self-reported symptom severity, condition-specific quality of life, adherence to pelvic floor muscle training (primary outcomes) and other extensive secondary outcomes among women with UI. We also aime...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Xu, X., Guo, P., Xu, P., Chen, D. D., Chen, W., Wang, H., Jin, Y., Wang, X., Zhang, W., Xie, F., Mao, M., Zhao, R., Feng, S. Tags: Open access, Urology Source Type: research
Hyperbaric oxygen therapy for poststroke insomnia: a systematic review and meta-analysis protocol
Introduction
Insomnia stands as a frequent consequence of a cerebrovascular event, afflicting a substantial fraction of those who endure the aftermath of stroke. The ramifications of insomnia following a stroke can further exacerbate cognitive and behavioural anomalies while hindering the process of neurological convalescence. While several randomised controlled trials (RCTs) have scrutinised the effects of hyperbaric oxygen therapy (HBOT) on poststroke insomnia, the advantages and drawbacks persist in a state of ambiguity. We advocate for a systematic review and meta-analysis of randomised clinical trials to comprehensive...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Shi, R., Meng, W., Liu, Z., Chang, L., Lu, R., Chen, X., Xue, W., Deng, Y. Tags: Open access, Neurology Source Type: research
Clinical variables associated with immune checkpoint inhibitor outcomes in patients with metastatic urothelial carcinoma: a multicentre retrospective cohort study
Conclusions
Our data identified BMI and bone metastases as novel clinical biomarkers that were independently associated with ICI outcomes in mUC. External and prospective validation are warranted. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Labidi, S., Meti, N., Barua, R., Li, M., Riromar, J., Jiang, D. M., Fallah-Rad, N., Sridhar, S. S., Del Rincon, S. V., Pezo, R. C., Ferrario, C., Cheng, S., Sacher, A. G., Rose, A. A. N. Tags: Open access, Oncology Source Type: research
Association between haemoglobin-to-red blood cell distribution width ratio at admission and all-cause mortality in adult patients with sepsis in an intensive care unit: a secondary analysis of the MIMIC-IV database
Conclusions
This retrospective analysis demonstrated that the HRR at the time of admission was a significant prognostic marker for long-term mortality in patients with sepsis. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Zhong, L., Zhong, Y., Chen, W., Liang, F., Liao, Y., Zhou, Y. Tags: Open access, Intensive care Source Type: research
impHFrEF trial: study protocol for an open-label, multicentre study of improvement the outcome of patients with heart failure in China using a mobile hEalth-supported platForm
Background
Patients with chronic heart failure (CHF) often have a long duration of illness, difficulty in attending follow-up visits, and poor adherence to treatment. As a result, they frequently cannot receive guideline-directed medical therapy (GDMT) at the desired or maximum tolerable drug dosage. This leads to high hospitalisation and mortality rates for HF patients. Therefore, effective management and monitoring of patients with HF to ensure they receive GDMT is crucial for improving the prognosis.
Design and methods
This is a multicentre, open-label, randomised, parallel-group study involving patients with CHF acros...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Chen, F., Li, G., Zhang, X., Shen, Q., Wang, F., Dong, X., Zou, Y., Chen, W., Xu, B., Wang, J. Tags: Open access, Cardiovascular medicine Source Type: research
Mixed-methods feasibility outcomes for a novel ACT-based video game 'ACTing Minds to support mental health
Conclusions
Implementation of the ‘ACTing Minds’ intervention is warranted, based on both qualitative and quantitative outcomes.
Trial registration number
NCT04566042 ClinicalTrials.gov (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Gordon, T. C., Kemp, A. H., Edwards, D. J. Tags: Open access, Mental health Source Type: research
Prognostic impact of combined non-severe aortic stenosis and mitral regurgitation on clinical outcomes: a single-centre retrospective study
Conclusion
Patients with combined non-severe AS and MR have a higher rate of HF hospitalisations and mortality. An AVA≤1.35 cm² in the presence of >mild MR is associated with worse clinical outcomes. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Granot, Y., Sapir, O. R., Laufer-Perl, M., Viskin, D., Banai, S., Topilsky, Y., Havakuk, O. Tags: Open access, Cardiovascular medicine Source Type: research
Development and content validation of a financial and functional outcomes tool for diabetes-related foot disease in patients undergoing major lower limb amputation: a prospective observational study from Pakistan
Conclusion
A 37-item multidimensional questionnaire was developed and rigorously content-validated to assess the financial and functional impact of major lower limb amputation in patients with diabetes-related foot disease. The questionnaire used in this study has shown robust content validity specifically for our population. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Siddiqui, N. A., Khaliq, M. A., Pirzada, M. A., Rehman, Z., Shaikh, F., Riaz, A., Khan, S. Tags: Open access, Surgery Source Type: research
