Urban environment and health: a cross-sectional multiregional project based on population health surveys in Spain (DAS-EP project) - study protocol
This study, Urban environment and health: a cross-sectional multiregional project based on population health surveys in Spain (DAS-EP project), aims to investigate the complex association between the urban environmental exposures (UrbEEs) and health.
Methods and analysis
DAS-EP is a Spanish multiregional cross-sectional project that combines population health surveys (PHS) and geographical information systems (GIS) allowing to collect rich individual-level data from 17 000 adult citizens participating in the PHS conducted in the autonomous regions of the Basque Country, Andalusia, and the Valencian Community, and the city...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Bereziartua, A., Cabrera-Leon, A., Subiza-Perez, M., Garcia-Baquero, G., Delis Gomez, S., Ballester, F., Estarlich, M., Merelles, A., Esplugues, A., Irles, M. A., Barona, C., Mas, R., Font-Ribera, L., Bartoll, X., Perez, K., Oliveras, L., Binter, A.-C., D Tags: Open access, Mental health Source Type: research
Protocol for a mixed-methods study to develop and feasibility test a digital system for the capture of patient-reported outcomes (PROs) in patients receiving chimeric antigen receptor T-cell (CAR-T) therapies (the PRO-CAR-T study)
This study will develop and evaluate feasibility of a new ePRO system for CAR-T patients in routine care.
Methods and analysis
Multiphase, mixed-methods study involving multiple stakeholder groups (patients, family members, carers, clinicians, academics/researchers and policy-makers). The intervention development phase comprises a Delphi study to select PRO measures for the digital system, a codesign workshop and consensus meetings to establish thresholds for notifications to the clinical team if a patient reports severe symptoms or side effects. Usability testing will evaluate how users interact with the digital system a...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Hughes, S. E., McMullan, C., Aiyegbusi, O. L., Shaw, K., Kinsella, F., Ferguson, P., Khatsuria, F., Burns, D., Pyatt, L., Ansell, J., Chakera, E., Richardson-Abraham, J., Denniston, A. K., Davies, E. H., Craddock, C., Calvert, M. Tags: Open access, Haematology (incl blood transfusion) Source Type: research
Decision to self-isolate during the COVID-19 pandemic in the UK: a rapid scoping review
Conclusions
Decisions to self-isolate after a positive test were influenced by multiple factors, including individuals’ beliefs, concerns, priorities and personal circumstances. Future testing strategies must facilitate meaningful financial, practical and mental health support to allow individuals to overcome the perceived and actual negative consequences of isolating. Clear, consistent communication of the purpose and procedures of isolating will also be critical to support compliance with self-isolation guidance, and should leverage people’s perceived value in protecting others. Building public trust is also ...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Keene, C. M., Dickinson, S., Naidoo, R., Andersen-Waine, B., Ferguson-Lewis, A., Polner, A., Amswych, M., White, L., Molyneux, S., Wanat, M., EY-Oxford Health Analytics Consortium, Moldokmatova, Polner, Ferguson-Lewis, Andersen-Waine, Gao, Franco, Keene, Tags: Open access, Public health, COVID-19 Source Type: research
Understanding the inclusion and participation of adults from Black African Diaspora Communities (BAFDC) in health and care research in the UK: a realist review protocol
Introduction
People from Black African Diaspora Communities (BAFDC) experience poorer health outcomes, have many long-term conditions and are persistently under-represented in health and care research. There is limited focus on programmes, or interventions that support inclusion and participation of people from BAFDC in research. Through coproduction, this realist review seeks to provide a programme theory explaining what context and mechanisms may be required, to produce outcomes that facilitate inclusion and participation for people from BAFDC in health and care research, in the UK.
Methods and analysis
A group of peopl...
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Hoverd, E., Effiom, V., Gravesande, D., Hollowood, L., Kelly, T., Mukuka, E., Owatemi, T., Sargeant, I., Ward, S., Spencer, R., Edge, D., Dale, J., Staniszewska, S. Tags: Open access, Health services research Source Type: research
Comparative examination of breast cancer burden in sub-Saharan Africa, 1990-2019: estimates from Global Burden of Disease 2019 study
Conclusion
The results show the increasing burden of breast cancer in sub-Saharan Africa and provide valuable information on the trends of breast cancer and the risk factors attributable to breast cancer across sociodemographic index, region and country. These findings may inform health policies and improve the rational allocation of health resources. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Igbokwe, K. K. Tags: Open access, Oncology Source Type: research
Time elapsed from definitive diagnosis to surgery for osteonecrosis of the femoral head: a nationwide observational study in Japan
Conclusion
ONFH has been considered to be an intractable disease that often requires surgical treatment, but the fact that surgery was performed in more than half of the patients within 9 months from diagnosis suggests severe disease with a significant clinical impact.
Trial registration number
Chiba University ID1049. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Nakamura, J., Fukushima, W., Ando, W., Hagiwara, S., Kawarai, Y., Shiko, Y., Kawasaki, Y., Sakai, T., Ito, K., Arishima, Y., Chosa, E., Fujimoto, Y., Fujiwara, K., Hasegawa, Y., Hayashi, S., Imagama, T., Inaba, Y., Ishibashi, Y., Ishidou, Y., Ito, H., Ito Tags: Open access, Rheumatology Source Type: research
Prevalence and impact of SARS-CoV-2 infection among patients with acute ischaemic stroke: a nationwide register-based cohort study in Denmark
Conclusion
In this nationwide study, only 0.6% of patients with acute ischaemic stroke were tested positive for a concurrent SARS-CoV-2 infection. The patients with SARS-CoV-2 presented with more severe strokes. (Source: BMJ Open)
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Mortensen, J. K., Blauenfeldt, R. A., Hedegaard, J. N., Morberg Wejse, C., Johnsen, S. P., Andersen, G., Simonsen, C. Z. Tags: Open access, Neurology, COVID-19 Source Type: research
Efficacy of acupuncture (Jins three-needle) on motor symptoms and anxiety in patients with Parkinsons disease: protocol for a multicentre, randomised, assessor-blinded clinical trial
Introduction
Parkinson’s disease (PD) has a significant impact on a substantial number of individuals in China. Notably, 31% of patients with PD also grapple with the additional burden of anxiety. This dual challenge of managing both PD and anxiety underscores the complexity of the condition and the diverse range of symptoms patients may experience. Considering the circumstances, the cost and potential drawbacks associated with traditional antiparkinsonian drugs become increasingly relevant. Acupuncture emerges as a significant non-pharmacological adjunct therapy. Offering a potentially safer and more cost-effective ...
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Liu, X., Fan, J., Leong, I. I., Lu, W., Zhang, Y., Gong, M., Zhuang, L. Tags: Open access, Neurology Source Type: research
How can we improve Comprehensive Geriatric Assessment for older people living with frailty in primary care and community settings? A qualitative study
Conclusions
Viable solutions to address gaps in the current delivery of CGA include the provision of training and support to use digital technology and a designated comprehensive care coordinator. The next stage of this research will use these findings, existing evidence and stakeholder engagement, to develop and refine a model of community-based CGA that can be assessed for feasibility and acceptability. (Source: BMJ Open)
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Mahmoud, A., Goodwin, V. A., Morley, N., Whitney, J., Lamb, S. E., Lyndon, H., Creanor, S., Frost, J., On behalf of the DREAM Study Team, on behalf of the DREAM Study Team, Clegg, Crocker, Din, Hamilton, Hulme, Sanders Tags: Open access, Geriatric medicine Source Type: research
First experience with nicotine products and transition to regular tobacco use: a secondary data analysis in 28 European countries
Conclusions
Although this study cannot infer causality, the findings show that odds of becoming a regular tobacco user differs widely depending on the first product used. Better understanding of the associations between first product use and regular tobacco use could be informative to tobacco control policy-makers and help tailor prevention programmes. (Source: BMJ Open)
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Rajani, N. B., Goyal, J., Filippidis, F. T. Tags: Open access, Public health Source Type: research
Suicide and self-harm by burns in Pakistan: a scoping review protocol
Introduction
Suicide is a global public health problem. Self-inflicted burns are one of the most severe methods of suicide, with high morbidity and mortality. Low-income and middle-income countries contribute 40% of all suicidal burns. Pakistan lacks comprehensive burns surveillance data, which prevents an understanding of the magnitude of the problem. This scoping review aims to understand the scope of the problem of suicide and self-harm burns in Pakistan and to identify knowledge gaps within the existing literature related to this specific phenomenon.
Methods and analysis
This scoping review will follow the methodologi...
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Noorullah, A., Pirani, S., Bebbington, E., Khan, M. Tags: Open access, Mental health Source Type: research
Longitudinal Resilience and Risk Factors in Pediatric Postoperative Pain (LORRIS): Protocol for a Prospective Longitudinal Swiss University Childrens Hospitals-Based Study
Introduction
Chronic postsurgical pain (CPSP) is defined as pain that persists after a surgical procedure and has a significant impact on quality of life. Previous studies show the importance of psychological factors in CPSP, yet the majority of studies focused solely on negative emotions. This longitudinal observational study aims to broaden this knowledge base by examining the role of emotional state, emotion variability, emotion regulation and emotion differentiation on the child and the parent level for the development CPSP, and to describe pain and emotion-related trajectories following surgery.
Methods and analysis
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Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Hochreuter, J., Dreher, T., Hasler, C.-C., Canonica, S., Locher, C., Held, U., Rabbitts, J., Koechlin, H. Tags: Open access, Paediatrics Source Type: research
Developing a reporting item checklist for studies of HIV drug resistance prevalence or incidence: a mixed methods study
Conclusions
We generated a list of reporting items for studies on the incidence or prevalence of HIV drug resistance along with an explanation of why researchers believe these items are important. Mixed methods allowed for the simultaneous generation and integration of the item list and qualitative insights. The integrated findings were then further developed to become the subsequently published reporting guidance. (Source: BMJ Open)
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Garcia, C., Holbrook, A., Djiadeu, P., Alvarez, E., Matos Silva, J., Mbuagbaw, L. Tags: Open access, Health services research Source Type: research
Behavioural 'nudging interventions to reduce low-value care for low back pain in the emergency department (NUDG-ED): protocol for a 2x2 factorial, before-after, cluster randomised trial
This study has ethical approval from Southwestern Sydney Local Health District Human Research Ethics Committee (2023/ETH00472). We will disseminate the results of this trial via media, presenting at conferences and scientific publications.
Trial registration number
ACTRN12623001000695. (Source: BMJ Open)
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Altinger, G., Sharma, S., Maher, C. G., Cullen, L., McCaffery, K., Linder, J. A., Buchbinder, R., Harris, I. A., Coiera, E., Li, Q., Howard, K., Coggins, A., Middleton, P. M., Gunja, N., Ferguson, I., Chan, T., Tambree, K., Varshney, A., Traeger, A. C., T Tags: Open access, Public health Source Type: research
Community-based interventions targeting multiple forms of malnutrition among adolescents in low-income and middle-income countries: protocol for a scoping review
Background
Adolescent malnutrition is a significant public health challenge in low-income and middle-income countries (LMICs), with long-term consequences for health and development. Community-based interventions have the potential to address multiple forms of malnutrition and improve the health outcomes of adolescents. However, there is a limited understanding of the content, implementation and effectiveness of these interventions. This scoping review aims to synthesise evidence on community-based interventions targeting multiple forms of malnutrition among adolescents in LMICs and describe their effects on nutrition and ...
Source: BMJ Open - March 28, 2024 Category: General Medicine Authors: Kurniawan, A. L., Ranisavljev, M., Partap, U., Shinde, S., Ferrero, E., Ostojic, S., Mkwanazi, N., Alangea, D. O., Neumann, C., Liu, S., Bärnighausen, T., Fawzi, W. W., ARISE-NUTRINT collaborators, Laxy, Burns, Pedron, Sando, Oduola, Moshabela, Si Tags: Open access, Nutrition and metabolism Source Type: research
