Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Clinical and molecular genetic analysis of cytologically uncertain thyroid nodules in patients with thyroid disease
CONCLUSIONS: Our experience implies that molecular genetic testing is one of several decision factors. We will continue to monitor and enlarge our patient cohort to obtain long-term follow-up data.PMID:38058193 | DOI:10.5507/bp.2023.048 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - December 7, 2023 Category: Biomedical Science Authors: Jindrich Lukas Barbora Hintnausova Vlasta Sykorova Martin Syrucek Marek Maly David Lukas Jaroslava Duskova Source Type: research

Levels of retinol and retinoic acid in pancreatic cancer, type-2 diabetes and chronic pancreatitis
CONCLUSION: Significant decrease in retinol and ATRA levels in PDAC compared to T2DM, healthy individuals and/or CHP supports existing evidence of the role of retinoids in PDAC. However, neither ATRA nor retinol are suitable for detection of early PDAC. Correlation of ATRA levels and IGFBP-2 provides new information about a possible IGF and retinol relationship.PMID:38058194 | DOI:10.5507/bp.2023.049 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - December 7, 2023 Category: Biomedical Science Authors: Pavel Hrabak Miroslava Zelenkova Tomas Krechler Jan Soupal Michal Vocka Tomas Hanus Lubos Petruzelka Stepan Svacina Ales Zak Tomas Zima Marta Kalousova Source Type: research

Mortality of hospitalized patients with COVID-19: Effects of treatment options (vitamin D, anticoagulation, isoprinosine, ivermectin) assessed by propensity score matching, retrospective analysis
CONCLUSION: Prophylactic-dose anticoagulation treatment in our study was found to be beneficial in comparison with the full dose. Supplementation with vitamin D did not show any meaningful benefit in terms of lowering the hospital mortality. Neither ivermectin nor, isoprinosine was found to significantly decrease hospital mortality.PMID:38050692 | DOI:10.5507/bp.2023.045 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - December 5, 2023 Category: Biomedical Science Authors: Jiri Plasek Jozef Dodulik Petr Gai Barbora Hrstkova Jan Skrha Lukas Zlatohlavek Renata Vlasakova Peter Danko Petr Ondracek Eva Cubova Bronislav Capek Marie Kollarova Tomas Furst Jan Vaclavik Source Type: research

Disposition of levobupivacaine during intraoperative continuous caudal epidural analgesia in a preterm neonate
CONCLUSION: The results confirm our hypothesis of altered pharmacokinetics in the preterm neonate. Therefore, levobupivacaine therapy in these patients should be carefully monitored. Since therapeutic drug monitoring of levobupivacaine is not established in clinical routines, we suggest monitoring the intraoperative pain profile using validated scores.TRIAL REGISTRATION: EudraCT number: 2020-000595-37.PMID:37997373 | DOI:10.5507/bp.2023.047 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - November 24, 2023 Category: Biomedical Science Authors: Jan Sipek Pavla Pokorna Martin Sima Jitka Styblova Vladimir Mixa Source Type: research