Acute drug intoxication in childhood: a 10-year retrospective observational single-centre study and case reports
CONCLUSION: Accidental drug intoxications most frequently occurred in the age group from one to three years old. The second highest incidence was among adolescents most of which were suicide attempts. Analgesics and psychoactive agents accounted for the majority of cases. Medications should be kept in places where children cannot reach them.PMID:37580980 | DOI:10.5507/bp.2023.032 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Petra Matalova Michal Buchta Vendula Drietomska Alena Spicakova Martin Wawruch Peter Ondra Karel Urbanek Source Type: research

Impaired intestinal permeability in patients with multiple sclerosis
CONCLUSIONS: In multiple sclerosis patients, the intestinal epithelium may be impaired with increased permeability, but without significant enterocyte damage characterized by intracellular protein leakage. Based on our data, CLDN3 serum levels appear to assess intestinal dysfunction in MS patients but mainly in treated ones.PMID:37581230 | DOI:10.5507/bp.2023.033 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Lenka Fialova Pavla Barilly Ivana Stetkarova Ales Bartos Libuse Noskova Denisa Zimova Michal Zido Iva Hoffmanova Source Type: research

Acute drug intoxication in childhood: a 10-year retrospective observational single-centre study and case reports
CONCLUSION: Accidental drug intoxications most frequently occurred in the age group from one to three years old. The second highest incidence was among adolescents most of which were suicide attempts. Analgesics and psychoactive agents accounted for the majority of cases. Medications should be kept in places where children cannot reach them.PMID:37580980 | DOI:10.5507/bp.2023.032 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Petra Matalova Michal Buchta Vendula Drietomska Alena Spicakova Martin Wawruch Peter Ondra Karel Urbanek Source Type: research

Impaired intestinal permeability in patients with multiple sclerosis
CONCLUSIONS: In multiple sclerosis patients, the intestinal epithelium may be impaired with increased permeability, but without significant enterocyte damage characterized by intracellular protein leakage. Based on our data, CLDN3 serum levels appear to assess intestinal dysfunction in MS patients but mainly in treated ones.PMID:37581230 | DOI:10.5507/bp.2023.033 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Lenka Fialova Pavla Barilly Ivana Stetkarova Ales Bartos Libuse Noskova Denisa Zimova Michal Zido Iva Hoffmanova Source Type: research

Acute drug intoxication in childhood: a 10-year retrospective observational single-centre study and case reports
CONCLUSION: Accidental drug intoxications most frequently occurred in the age group from one to three years old. The second highest incidence was among adolescents most of which were suicide attempts. Analgesics and psychoactive agents accounted for the majority of cases. Medications should be kept in places where children cannot reach them.PMID:37580980 | DOI:10.5507/bp.2023.032 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Petra Matalova Michal Buchta Vendula Drietomska Alena Spicakova Martin Wawruch Peter Ondra Karel Urbanek Source Type: research

Impaired intestinal permeability in patients with multiple sclerosis
CONCLUSIONS: In multiple sclerosis patients, the intestinal epithelium may be impaired with increased permeability, but without significant enterocyte damage characterized by intracellular protein leakage. Based on our data, CLDN3 serum levels appear to assess intestinal dysfunction in MS patients but mainly in treated ones.PMID:37581230 | DOI:10.5507/bp.2023.033 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Lenka Fialova Pavla Barilly Ivana Stetkarova Ales Bartos Libuse Noskova Denisa Zimova Michal Zido Iva Hoffmanova Source Type: research

Acute drug intoxication in childhood: a 10-year retrospective observational single-centre study and case reports
CONCLUSION: Accidental drug intoxications most frequently occurred in the age group from one to three years old. The second highest incidence was among adolescents most of which were suicide attempts. Analgesics and psychoactive agents accounted for the majority of cases. Medications should be kept in places where children cannot reach them.PMID:37580980 | DOI:10.5507/bp.2023.032 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Petra Matalova Michal Buchta Vendula Drietomska Alena Spicakova Martin Wawruch Peter Ondra Karel Urbanek Source Type: research

Impaired intestinal permeability in patients with multiple sclerosis
CONCLUSIONS: In multiple sclerosis patients, the intestinal epithelium may be impaired with increased permeability, but without significant enterocyte damage characterized by intracellular protein leakage. Based on our data, CLDN3 serum levels appear to assess intestinal dysfunction in MS patients but mainly in treated ones.PMID:37581230 | DOI:10.5507/bp.2023.033 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Lenka Fialova Pavla Barilly Ivana Stetkarova Ales Bartos Libuse Noskova Denisa Zimova Michal Zido Iva Hoffmanova Source Type: research

Acute drug intoxication in childhood: a 10-year retrospective observational single-centre study and case reports
CONCLUSION: Accidental drug intoxications most frequently occurred in the age group from one to three years old. The second highest incidence was among adolescents most of which were suicide attempts. Analgesics and psychoactive agents accounted for the majority of cases. Medications should be kept in places where children cannot reach them.PMID:37580980 | DOI:10.5507/bp.2023.032 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Petra Matalova Michal Buchta Vendula Drietomska Alena Spicakova Martin Wawruch Peter Ondra Karel Urbanek Source Type: research

Impaired intestinal permeability in patients with multiple sclerosis
CONCLUSIONS: In multiple sclerosis patients, the intestinal epithelium may be impaired with increased permeability, but without significant enterocyte damage characterized by intracellular protein leakage. Based on our data, CLDN3 serum levels appear to assess intestinal dysfunction in MS patients but mainly in treated ones.PMID:37581230 | DOI:10.5507/bp.2023.033 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Lenka Fialova Pavla Barilly Ivana Stetkarova Ales Bartos Libuse Noskova Denisa Zimova Michal Zido Iva Hoffmanova Source Type: research

Acute drug intoxication in childhood: a 10-year retrospective observational single-centre study and case reports
CONCLUSION: Accidental drug intoxications most frequently occurred in the age group from one to three years old. The second highest incidence was among adolescents most of which were suicide attempts. Analgesics and psychoactive agents accounted for the majority of cases. Medications should be kept in places where children cannot reach them.PMID:37580980 | DOI:10.5507/bp.2023.032 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Petra Matalova Michal Buchta Vendula Drietomska Alena Spicakova Martin Wawruch Peter Ondra Karel Urbanek Source Type: research

Impaired intestinal permeability in patients with multiple sclerosis
CONCLUSIONS: In multiple sclerosis patients, the intestinal epithelium may be impaired with increased permeability, but without significant enterocyte damage characterized by intracellular protein leakage. Based on our data, CLDN3 serum levels appear to assess intestinal dysfunction in MS patients but mainly in treated ones.PMID:37581230 | DOI:10.5507/bp.2023.033 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - August 15, 2023 Category: Biomedical Science Authors: Lenka Fialova Pavla Barilly Ivana Stetkarova Ales Bartos Libuse Noskova Denisa Zimova Michal Zido Iva Hoffmanova Source Type: research

Retinal microvascular abnormalities in major depression
CONCLUSION: According to the literature, acute and chronic neuroinflammation is associated with changes in microvascular form and function. The endothelium becomes a major participant in the inflammatory response damaging the surrounding tissue and its function. Because the retina and brain tissue share a common embryonic origin, we suspect similar microvascular pathology in the retina and in the brain in major depression. Our results may contribute to a better understanding of depression etiopathogenesis and to its personalized treatment.PMID:37465892 | DOI:10.5507/bp.2023.026 (Source: Biomedical Papers of the Medical Fac...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - July 19, 2023 Category: Biomedical Science Authors: Evgenii Sadykov Ladislav Hosak Alexandr Stepanov Jana Zapletalova Jan Studnicka Source Type: research

Gamma-glutamyltransferase-associated glycoprotein patterns in human seminal plasma of normozoospermic men: a new aspect of biomarker heterogeneity
CONCLUSIONS: GGT contributes to several molecular patterns that differ between the soluble and extracellular vesicle fractions of hSP. Their glycobiochemical heterogeneity is due to difference in the presence of distinct sialylated and mannosylated glycans. Moreover, GGT-associated glycoprotein patterns differentiate between high molecular mass forms of GGT in the soluble fraction of hSP. They hold promise as possible targets for increasing biomarker potential of GGT.PMID:37465893 | DOI:10.5507/bp.2023.031 (Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub)
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - July 19, 2023 Category: Biomedical Science Authors: Tamara Jankovic Jelena Danilovic Lukovic Sanja Goc Ninoslav Mitic Ljiljana Hajdukovic Miroslava Jankovic Source Type: research

Retinal microvascular abnormalities in major depression
CONCLUSION: According to the literature, acute and chronic neuroinflammation is associated with changes in microvascular form and function. The endothelium becomes a major participant in the inflammatory response damaging the surrounding tissue and its function. Because the retina and brain tissue share a common embryonic origin, we suspect similar microvascular pathology in the retina and in the brain in major depression. Our results may contribute to a better understanding of depression etiopathogenesis and to its personalized treatment.PMID:37465892 | DOI:10.5507/bp.2023.026 (Source: Biomedical Papers of the Medical Fac...
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - July 19, 2023 Category: Biomedical Science Authors: Evgenii Sadykov Ladislav Hosak Alexandr Stepanov Jana Zapletalova Jan Studnicka Source Type: research