Late Cochlear Implantation in Early-Deafened Adults: A Detailed Analysis of Auditory and Self-Perceived Benefits
Conclusions: Outcome measurement in this population should be adjusted to the patients ’ individual performance level and include self-perceived benefit. There is still a need for more knowledge regarding predictors of CI outcomes in this group, but the current study suggests the importance of the preoperative performance of the ear to be implanted.Audiol Neurotol 2017;22:364 –376 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 28, 2018 Category: Audiology Source Type: research

The Effect of Binaural Beamforming Technology on Speech Intelligibility in Bimodal Cochlear Implant Recipients
The objective of this study was to investigate the effect of a binaural beamformer for bimodal cochlear implant (CI) users. This prospective study measured speech reception thresholds (SRT) in noise in a repeated-measures design that varied in listening modality for static and dynamic listening conditions. A significant improvement in SRT of 4.7 dB was found with the binaural beamformer switched on in the bimodal static listening condition. No significant improvement was found in the dynamic listening condition. We conclude that there is a clear additional advantage of the binaural beamformer in bimodal CI users for predic...
Source: Audiology and Neurotology - June 22, 2018 Category: Audiology Source Type: research

Cochlear Nerve Aplasia with Detectable Olivocochlear Efferent Function: A Distinct Presentation of Auditory Neuropathy Spectrum Disorder
Conclusions: Children with unilateral ANSD can have normal efferent cochlear nerve function despite MRI evidence of ipsilateral CNA. The importance of these findings for newborn hearing screening and cochlear implantation is discussed.Audiol Neurotol 2018;23:39 –47 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 22, 2018 Category: Audiology Source Type: research

Abnormal Cochleovestibular Anatomy and Hearing Outcomes: Pediatric Patients with a Questionable Cochleovestibular Nerve Status May Benefit from Cochlear Implantation and/or Hearing Aids
Conclusions: Current imaging cannot accurately characterize the functional status of the CVN or predict an assistive device benefit. Children who would have otherwise been denied a CI exhibited auditory responses after implantation. A CI should be considered in children with abnormal CVN. Furthermore, imaging acquisition protocols need standardization for clear temporal bone imaging.Audiol Neurotol 2018;23:48 –57 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 22, 2018 Category: Audiology Source Type: research

One-Year Results for Patients with Unilateral Hearing Loss and Accompanying Severe Tinnitus and Hyperacusis Treated with a Cochlear Implant
Conclusion: A CI should be considered as a treatment option in patients with UHL and a concomitant severe tinnitus handicap. However, appropriate counselling of candidates on the anticipated risks, benefits, and limitations that are inherent to cochlear implantation is imperative.Audiol Neurotol 2018;23:8 –19 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 21, 2018 Category: Audiology Source Type: research

Methionine Sulfoxide Reductase A Knockout Mice Show Progressive Hearing Loss and Sensitivity to Acoustic Trauma
Methionine sulfoxide reductases (MsrA andMsrB) protect the biological activity of proteins from oxidative modifications to methionine residues and are important for protecting against the pathological effects of neurodegenerative diseases. In the current study, we characterized the auditory phenotype of theMsrA knockout mouse. YoungMsrA knockout mice showed small high-frequency threshold elevations for auditory brainstem response and distortion product otoacoustic emission compared to those of wild-type mice, which progressively worsened in olderMsrA knockout mice.MsrA knockout mice showed an increased sensitivity to noise...
Source: Audiology and Neurotology - June 21, 2018 Category: Audiology Source Type: research

Effect of Antioxidant Vitamins as Adjuvant Therapy for Sudden Sensorineural Hearing Loss: Systematic Review Study
Conclusions and Relevance: The success of the treatment is increased in patients who received antioxidant vitamins in combination with conventional therapy.Audiol Neurotol 2018;23:1-7 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 21, 2018 Category: Audiology Source Type: research

Predicting Sequential Cochlear Implantation Performance: A Systematic Review
This systematic review of the literature reveals which pre ­operative factors affect sequential cochlear implantation outcomes in adults. The findings can help health care prof­essionals provide evidence-based advice on the expected benefits from a second cochlear implant (CI). We searched PubMed, EMBASE, and the Cochrane database from November 1977 to Au gust 26, 2017, using the terms “sequential cochlear implantation”; the most frequently cited predictors for unilateral cochlear implantation performance and other potential predictors for sequential implantation outcome; and “speech perception,” “localization...
Source: Audiology and Neurotology - May 2, 2018 Category: Audiology Source Type: research

Long-Term Hearing Outcomes following Stapedotomy in Patients with Otosclerosis and Preoperative Small Air-Bone Gap
Conclusions: Even though long-term hearing levels will evolve similarly in patients with ≤20 and #x3e; 20 dB preoperative ABGs, the lack of clinical improvement found in the small ABG group is not in favor of an early surgery.Audiol Neurotol 2017;22:350 –355 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - April 26, 2018 Category: Audiology Source Type: research

Long-Term Effects of Middle Ear Tendon Resection on Middle Ear Myoclonic Tinnitus, Hearing, and Hyperacusis
Conclusions: METR seems to be an effective and safe treatment option for intractable MEMT, considering its high control rate of tinnitus and no long-term harmful effects on hearing and hyperacusis.Audiol Neurotol 2017;22:343 –349 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - April 12, 2018 Category: Audiology Source Type: research

Localization and Spatial Discrimination in Children and Adolescents with Moderate Sensorineural Hearing Loss Tested without Their Hearing Aids
The present study investigated two measures of spatial acoustic perception in children and adolescents with sensorineural hearing loss (SNHL) tested without their hearing aids and compared it to age-matched controls. Auditory localization was quantified by means of a sound source identification task and auditory spatial discrimination acuity by measuring minimum audible angles (MAA). Both low- and high-frequency noise bursts were employed in the tests to separately address spatial auditory processing based on interaural time and intensity differences. In SNHL children, localization (hit accuracy) was significantly reduced ...
Source: Audiology and Neurotology - March 1, 2018 Category: Audiology Source Type: research

Hearing Preservation with the Slim Modiolar Electrode Nucleus CI532 ® Cochlear Implant: A Preliminary Experience
As the indications for cochlear implant have expanded to include younger patients and individuals with greater degrees of residual hearing, increasing emphasis has been placed on atraumatic surgery and the preservation of the cochlear structure. Here, a descriptive prospective randomized study was performed. It was shown that residual hearing preservation is possible 12 months postoperatively with an atraumatic perimodiolar flexible electrode array CI532 ® (Cochlear Ltd, Sydney, Australia). Residual hearing preservation, considered as #x3c; 15 dB, was obtained in 70% of the cases. Better clinical outcomes and performance ...
Source: Audiology and Neurotology - February 27, 2018 Category: Audiology Source Type: research

A Trend in Sudden Sensorineural Hearing Loss: Data from a Population-Based Study
In conclusion, this large-scale study indicates that unilateral SSNHL has a higher incidence among the elderly, women, and in autumn (i.e., along with colder w eather).Audiol Neurotol 2017;22:311 –316 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - February 20, 2018 Category: Audiology Source Type: research

Resveratrol Promotes Recovery of Hearing following Intense Noise Exposure by Enhancing Cochlear SIRT1 Activity
The sirtuin SIRT1 is a highly conserved nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylase known to have protective effects against a wide range of neurological disorders. In the present study, we discovered that C57BL/6 mice fed a long-term diet supplemented with high-dose resveratrol exhibited increased cochlear SIRT1 activity and presented a better recovery of hearing and less loss of hair cells after intense noise exposure compared with those fed a standard chew. Moreover, resveratrol attenuated cochlear SIRT1 decrease and reduced oxidative stress in the cochlea after noise exposure. These results su...
Source: Audiology and Neurotology - January 25, 2018 Category: Audiology Source Type: research

Role of the Frontal Sinus in Mediating Ocular Vestibular-Evoked Myogenic Potentials by Bone Vibration Stimuli Applied to the Forehead
In conclusion, the height of the frontal sinus plays a role in mediating the elicitation of oVEMPs. The oVEMPs could be easily elicited by the first-order bone vibration (Fpz/Fz tapping) coupled with the second-order r esonance effect (with a high extent of the frontal sinus). Thus, initial tapping at the Fpz site is suggested. If it fails, try the Fz site for screening the oVEMPs.Audiol Neurotol 2017;22:272-281 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - January 17, 2018 Category: Audiology Source Type: research