Comparison of Therapeutic Results with/without Additional Hyperbaric Oxygen Therapy in Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Prospective Study
Conclusions: HBO combined with pharmacological treatments leads to better hearing recovery than pharmacological treatments alone.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 12, 2020 Category: Audiology Source Type: research

A Novel Cadherin 23 Variant for Hereditary Hearing Loss Reveals Additional Support for a DFNB12 Nonsyndromic Phenotype of CDH23
Conclusions:The present study shows that an accurate molecular diagnosis based on NGS technologies largely improves molecular-diagnostic outcome and thus genetic counseling, and helps to clarify the recurrence risk in deaf families.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 2, 2020 Category: Audiology Source Type: research

Evaluation of Subtotal Petrosectomy Technique in Difficult Cases of Cochlear Implantation
Conclusions: When CI is intended in technically challenging cases or associated with a high risk of complications, STP is effective and reliable. Safe implantation and excellent long-term outcomes can be achieved provided surgical steps are properly followed. Single-stage procedures can be performed in most cases, even when there is active middle-ear disease.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 29, 2020 Category: Audiology Source Type: research

Eustachian Tube Function in Patients with Symptoms on Baro-Challenge
Conclusion: The relationship between aural pain during baro-challenge and ET function appears more complex than had been assumed, with pain possibly related to factors other than just ET function.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 26, 2020 Category: Audiology Source Type: research

Comparing Light-Driven Contact Hearing Aids with Acoustic Hearing Aids: Data and Clinical Tips
Conclusions: For proper audiometric and otologic candidates, this light-driven CHA can offer significant improvements in high-frequency sound fidelity, word recognition, and sound quality compared to AHA technology. Administering questionnaires was helpful in illuminating real-world improvements. Device fit, alignment, and quality control issues are improving, though still contributing to high device return rates at this time. Operational factors should be considered when incorporating CHA into a hearing health care practice.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 13, 2020 Category: Audiology Source Type: research

Audiological Evaluation of Vestibular Schwannoma Patients with Normal Hearing
Conclusions: The diagnosis of VS should not be based on audiometric thresholds alone. Alarming signs of VS should be clear to the physician in order not to miss or delay the diagnosis of the disease. The ABR is useful in the diagnosis of VS, but normal results do not exclude the occurrence of the disease in patients with normal hearing.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - July 2, 2019 Category: Audiology Source Type: research

How Does Nonverbal Reasoning Affect Sentence Recognition in Adults with Cochlear Implants and Normal-Hearing Peers?
Conclusions: Neurocognitive functions contributed differentially to nonverbal reasoning performance in CI users as compared with NH peers, and nonverbal reasoning appeared to partially mediate the effects of these different neurocognitive functions on sentence recognition in both groups, at least for PRESTO sentences. Slower information processing speed accounted for poorer nonverbal reasoning scores in CI users. Thus, it may be that prolonged auditory deprivation contributes to cognitive decline through slower information processing.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - July 2, 2019 Category: Audiology Source Type: research

Clinical Implications of Poloxamer 407 as Packing Material in an Animal Model
Conclusions: This study suggested that P407 is feasible as a packing material to handle with one hand and to prevent adhesion, especially in infected middle ear mucosa. Although there is a lack of data on how well P407 supports grafts, we suggest that P407 could be a candidate for packing material in endoscopic ear surgery.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - June 17, 2019 Category: Audiology Source Type: research

Tophaceous Gout of the Middle Ear: Case Reports and Review of the Literature
Tophaceous gout of the middle ear is a rare occurrence that presents as a granular white-colored mass. It is frequently misdiagnosed as cholesteatoma or tympanosclerosis in patients who otherwise may not manifest any clinical or biochemical signs of gout. While uncommon, it can lead to clinically significant disease such as conductive hearing loss. The present report describes 2 cases of middle ear gouty tophi initially mistaken for another entity. Both patients underwent surgery, and the diagnosis of gout was revealed after final histopathological analysis. A review of the literature is also presented.Audiol Neurotol (Sou...
Source: Audiology and Neurotology - June 5, 2019 Category: Audiology Source Type: research

The Bonebridge in Adults with Mixed and Conductive Hearing Loss: Audiological and Quality of Life Outcomes
Conclusions: The Bonebridge provides not only significant audiological benefit in both speech understanding in quiet and in noise, but also increases self-perceived quality of life in patients suffering from mixed and conductive hearing loss. Together with a very low rate and minor nature of adverse events, it is the state-of-the-art solution for hearing rehabilitation in patients with mixed or conductive hearing loss up to a bone conduction threshold of 45 dB HL.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 29, 2019 Category: Audiology Source Type: research

Risk Factors and Prognostic Factors of Hearing Impairment in Neonatal Intensive Care Unit-Treated Infants
Conclusions: Factors related to the elevation of ABR threshold were oxygen administration and the presence of chromosomal aberrations. Awareness of risk factors that are more likely to cause hearing loss in infants may aid in follow-up treatment of these children.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 27, 2019 Category: Audiology Source Type: research

Cochlear Implant in the Elderly: Results in Terms of Speech Perception and Quality of Life
Discussion: In line with the literature, our data confirm that CI is an effective procedure also in elderly patients, conferring benefits in speech perception and quality of life.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 22, 2019 Category: Audiology Source Type: research

Insulin Receptor and Glucose Transporters in the Mammalian Cochlea
Insulin receptors are expressed on nerve cells in the mammalian brain, but little is known about insulin signaling and the expression of the insulin receptor (IR) and glucose transporters in the cochlea. We performed immunohistochemistry and gene/protein expression analysis to characterize the expression pattern of the IR and glucose transporters in the mouse organ of Corti (OC). We also performed glucose uptake assays to explore the action of insulin and the effects of pioglitazone, an insulin sensitizer, on glucose transport in the OC. Western blots of protein extracts from OCs showed high expression of IR and glucose tr...
Source: Audiology and Neurotology - May 22, 2019 Category: Audiology Source Type: research

MRI Metal Artifact Reduction Sequence for Auditory Implants: First Results with a Transcutaneous Bone Conduction Implant
Conclusion: The sequence for metal artifact reduction optimized in Bern enables MRI at 1.5 T in patients with active transcutaneous bone conduction implants without sacrificing diagnostic imaging quality. Particularly on the implanted side, imaging of intracranial and supra- and infratentorial brain pathologies is clinically more valuable than standard diagnostic MRI without any artifact reduction sequences.Audiol Neurotol (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 8, 2019 Category: Audiology Source Type: research

Erratum
Audiol Neurotol 2019;24:49 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - May 6, 2019 Category: Audiology Source Type: research