The Value of Unilateral CIs, CI-CROS and Bilateral CIs, with and without Beamformer Microphones, for Speech Understanding in a Simulation of a Restaurant Environment
Conclusions: CI-CROS is a valuable addition to the hardware options available to patients fit with a single CI. For patients fit with bilateral CIs, bilateral beamformers are a valuable addition in the condition of speech coming from in front of the listener. The small differences in performance in the CI-CROS and bilateral CI conditions suggest that patient preference for bilateral CIs is based largely on factors other than speech understanding in noise.Audiol Neurotol 2018;23:270 –276 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - December 13, 2018 Category: Audiology Source Type: research
The Efficacy of Concurrent or Sequential Intravenous and Intratympanic Steroid for Idiopathic Sudden Sensorineural Hearing Loss
Conclusion: The findings suggest that both concurrent and sequential treatment improve hearing in patients with idiopathic SSNHL, and that concurrent treatment may show greater benefit than sequential therapy, particularly at high frequencies.Audiol Neurotol 2018;23:277 –284 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - December 13, 2018 Category: Audiology Source Type: research
Viewing Target Distance Influences the Vestibulo-Ocular Reflex Gain when Assessed Using the Video Head Impulse Test
Gaze stabilization during head movements is provided by the vestibulo-ocular reflex (VOR). Clinical assessment of this reflex is performed using the video Head Impulse Test (vHIT). To date, the influence of different fixation distances on VOR gain using the vHIT has not been explored. We assessed the effect of target proximity on the horizontal VOR using the vHIT. Firstly, we assessed the VOR gain in 18 healthy subjects with 5 viewing target distances (150, 40, 30, 20, and 10 cm). The gain increased significantly as the viewing target distance decreased. A second experiment on 10 subjects was performed in darkness whilst t...
Source: Audiology and Neurotology - December 13, 2018 Category: Audiology Source Type: research
Progression of Hearing Loss in the Aging Population: Repeated Auditory Measurements in the Rotterdam Study
We quantified changes in the auditory acuity of 675 aging adults (mean age 71.1 years, 52.0% female, mean follow-up 4.4 years ± 0.2) of an ongoing cohort study with a pure-tone audiogram and a speech-in-noise test. Generalized estimating equation models were used to study the association between hearing loss and the progression with age, sex, education, cognition, BMI, blood pressure, having type 2 diabetes mellitus, chol esterol ratio, smoking and alcohol consumption. The mean progression of hearing loss was 0.29 and 1.35 dB/year (low and high frequencies). Progression of hearing loss was associated with baseline hearing...
Source: Audiology and Neurotology - December 13, 2018 Category: Audiology Source Type: research
Measurements of Trunk Sway for Stance and Gait Tasks 2 Years after Vestibular Neurectomy
The aim of this study was to investigate changes in balance control for stance and gait tasks in patients 2 years before and after vestibular neurectomy (VN) performed to alleviate intractable Meniere ’s disease. Amplitudes of trunk sway in roll and pitch directions were measured for stance and gait tasks in 19 patients using gyroscopes mounted at the lower-back. Measurements before VN and 2 years later were compared to those of healthy age-matched controls (HC). We also examined if changes in trunk sway amplitudes were correlated with patients’ subjective assessment of disability using the AAO-HNS scale. For patients ...
Source: Audiology and Neurotology - December 13, 2018 Category: Audiology Source Type: research
Dexamethasone and Dexamethasone Phosphate Entry into Perilymph Compared for Middle Ear Applications in Guinea Pigs
Dexamethasone phosphate is widely used for intratympanic therapy in humans. We assessed the pharmacokinetics of dexamethasone entry into perilymph when administered as a dexamethasone phosphate solution or as a micronized dexamethasone suspension, with and without inclusion of poloxamer gel in the medium. After a 1-h application to guinea pigs, 10 independent samples of perilymph were collected from the lateral semicircular canal of each animal, allowing entry at the round window and stapes to be independently assessed. Both forms of dexamethasone entered the perilymph predominantly at the round window (73%), with a lower ...
Source: Audiology and Neurotology - November 29, 2018 Category: Audiology Source Type: research
Working Memory Function in Children with Single Side Deafness Using a Bone-Anchored Hearing Implant: A Case-Control Study
This study aims at evaluating the effects of a bone-anchored hearing implant (BAHI) on speech perception, speech processing, and memory abilities in children with single side deafness (SSD). We enrolledn = 25 children with SSD and assessed them prior to BAHI implantation, and at 1-month and 3-month follow-ups after BAHI implantation using tests of perception in silence and perception in phonemic confusion, dictation in silence and noise, and working memory and short-term memory function in conditions of silence and noise. We also enrolled and evaluatedn = 15 children with normal hearing. We found a statistically significan...
Source: Audiology and Neurotology - November 15, 2018 Category: Audiology Source Type: research
Visual Analogue Scales as a Tool for Initial Assessment of Tinnitus Severity: Psychometric Evaluation in a Clinical Population
The aim of this study was to evaluate the psychometric properties of patient-reported visual analogue scale (VAS) ratings. All of the participants (100 Polish-speaking adults) completed a Tinnitus Functional Index (TFI) once and a 4-component VAS twice over a period of 3 days. Spearman ’s correlation coefficients between the VAS score and global TFI ranged from ρ = 0.52 for VAS-coping (VAS-C) to ρ= 0.81 for VAS-annoyance (VAS-A). Using the Bland-Altman method, the agreement ranged from 93% for VAS-A to 96% for VAS-distress (VAS-D). Interclass correlation coefficients ranged from 0.67 for VAS-C to 0.90 for VAS-A. The VA...
Source: Audiology and Neurotology - November 15, 2018 Category: Audiology Source Type: research
Dynamic Postural Stability and Hearing Preservation after Cochlear Implantation
Conclusion: Single-sided cochlear implantation does not adversely affect dynamic postural stability 5 weeks after surgery. Loss of functional residual hearing is not correlated with a decrease in dynamic postural stability.Audiol Neurotol 2018;23:222 –228 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - November 14, 2018 Category: Audiology Source Type: research
Performance with an Auditory Brainstem Implant and Contralateral Cochlear Implant in Pediatric Patients
Conclusions: We observed continued improvement in CI performance over time, even if no benefit was evident before the decision for ABI. This could suggest that ABI and CI have a synergistic effect, or it could simply be the adaptive ability of the developing brain to utilize the signals coming from these devices. There is preliminary evidence to support choosing the ear contralateral to the CI for an ABI in a pediatric patient with bilateral cochlear nerve deficiency.Audiol Neurotol 2018;23:216 –221 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - November 2, 2018 Category: Audiology Source Type: research
Comparison of Two Different Treatment Protocols Using Systemic and Intratympanic Steroids with and without Hyperbaric Oxygen Therapy in Patients with Severe to Profound Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Trial
Conclusion: These results demonstrate that the addition of HBOT to steroid combination therapy does not improve the average PTA values in severe to profound ISSNHL; however, it was associated with a better outcome at 500 Hz 1 month after treatment and, at 1 kHz, WDS 3 months after treatment. The sum of complete and partial hearing recovery was significantly higher for the study group than for the control group.Audiol Neurotol 2018;23:199 –207 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - October 31, 2018 Category: Audiology Source Type: research
The Effect of the MicroRNA-183 Family on Hair Cell-Specific Markers of Human Bone Marrow-Derived Mesenchymal Stem Cells
Hearing loss is considered the most common sensory disorder across the world. Nowadays, a cochlear implant can be an effective treatment for patients. Moreover, it is often believed that sensorineural hearing loss in humans is caused by loss or disruption of the function of hair cells in the cochlea. In this respect, mesenchymal cells can be a good candidate for cell-based therapeutic approaches. To this end, the potential of human bone marrow-derived mesenchymal stem cells to differentiate into hair cells with the help of transfection of microRNA in vitro was investigated. MicroRNA mimics (miRNA-96, 182, and 183) were tra...
Source: Audiology and Neurotology - October 31, 2018 Category: Audiology Source Type: research
Binaural Perception in Single-Sided Deaf Cochlear Implant Users with Unrestricted or Restricted Acoustic Hearing in the Non-Implanted Ear
In this study, we report results from a French clinical trial for CI in in SSD patients (NCT02204618). Localization, spe ech reception thresholds (SRTs) in noise, tinnitus severity, and QoL were evaluated in 18 SSD patients 1 year after CI. Data were analyzed for 2 subject groups according to the pure-tone average thresholds in the non-implanted ear: unrestricted acoustic hearing (UNRES; ≤25 dB HL;n = 10) and restricted acoustic hearing (RES; #x3e; 25 dB HL;n = 8). Across all subjects, localization was significantly better with the CI on than off (p = 0.005); there was no significant difference between subject groups (p ...
Source: Audiology and Neurotology - October 24, 2018 Category: Audiology Source Type: research
The Effects of Gusher-Related Intracochlear Pressure Changes on Hearing Preservation in Cochlear Implantation: A Comparative Series
Conclusion: The present study suggests that intraoperative gusher is associated with a significant drop in residual hearing, both immediately and over time, which may be related to the large change in intracochlear pressure intraoperatively.Audiol Neurotol 2018;23:181 –186 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - October 10, 2018 Category: Audiology Source Type: research
An Analysis of the Association between Epilepsy-Related Genes and Vertigo in the Polish Population
Considering the possibility of a common genetic background of vertigo and epilepsy, we genotyped an affected group of individuals with vertigo and an unaffected group, by studying 26 single-nucleotide polymorphisms (SNPs) in 14 genes which were previously reported to be of particular importance for epilepsy. Significant differences were found between the patients and the control group ( χ2 = 38.3, df = 3,p = 1.6 × 10–7) for the frequencies of haplotypes consist ing of 2 SNPs located in chromosome 11 (rs1939012 and rs1783901 within genesMMP8 andSCN3B, respectively). The haplotype rs1939012:C-rs1783901:A, consisting of t...
Source: Audiology and Neurotology - October 9, 2018 Category: Audiology Source Type: research
