Hyperbaric Oxygen Therapy as Concurrent Treatment with Systemic Steroids for Idiopathic Sudden Sensorineural Hearing Loss: A Comparison of Three Different Steroid Treatments
We analyzed 356 patients with idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy and systemic steroids (n = 161), systemic steroids alone (n = 160), or intratympanic and systemic steroids (n = 35). The main outcome measure was the hearing recovery rate. The effect of other variables, including the initial averaged 5-frequency hearing level, patient age, interval between the onset of symptoms and treatment, presence of vertigo as a complication, presence of diabetes mellitus, smoking history, and presence of hypertension, on the hearing recovery rate was also evaluated. The overall hearing r...
Source: Audiology and Neurotology - October 9, 2018 Category: Audiology Source Type: research
Cortical Processing of Frequency Changes Reflected by the Acoustic Change Complex in Adult Cochlear Implant Users
The purpose of this study was to examine neural substrates of frequency change detection in cochlear implant (CI) recipients using the acoustic change complex (ACC), a type of cortical auditory evoked potential elicited by acoustic changes in an ongoing stimulus. A psychoacoustic test and electroencephalographic recording were administered in 12 postlingually deafened adult CI users. The stimuli were pure tones containing different magnitudes of upward frequency changes. Results showed that the frequency change detection threshold (FCDT) was 3.79% in the CI users, with a large variability. The ACC N1 ’ latency was signif...
Source: Audiology and Neurotology - October 9, 2018 Category: Audiology Source Type: research
Balance Control during Stance and Gait after Cochlear Implant Surgery
Conclusion: Across all CI patients, CI surgery has a minor effect on balance control 2 months postoperatively. However, for patients younger than 60 years and those with normal balance control preoperatively, balance control worsened for gait indicating the need for preoperative counseling.Audiol Neurotol 2018;23:165 –172 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - October 9, 2018 Category: Audiology Source Type: research
Id1/NR2B Receptor Pathway Regulates Rat Cochlear Sensory Epithelial Cell Survival after Radiation
Survival of cochlear sensory epithelial cells may be regulated by inhibitor of differentiation-1 (Id1) and the N-methyl-D-aspartic acid (NMDA) receptor. However, it is unclear whether Id1 and the NMDA receptor are involved in the radiation-mediated survival of rat cochlear sensory epithelial cells. Here, we show that the percentage of apoptotic cells increased, the percentage of cells in the S phase decreased, Id1 mRNA and protein expression decreased and the NMDA receptor subtype 2B (NR2B) mRNA and protein level increased in OC1 cells after radiation. Cells infected with the Id1 gene exhibited higher Id1 mRNA and protein ...
Source: Audiology and Neurotology - October 9, 2018 Category: Audiology Source Type: research
Pediatric Auditory Brainstem Implantation: Impact on Audiological Rehabilitation and Tonal Language Development
Conclusion: Encouraging results of speech development were found, especially with continued use of the ABI. There was considerable variation in outcomes. Children with coexisting developmental and nonauditory cognitive disabilities did not perform as well. Auditory brainstem implantation is a safe and beneficial treatment for profound prelingual deafness in Cantonese-speaking pediatric patients.Audiol Neurotol 2018;23:126 –134 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - September 18, 2018 Category: Audiology Source Type: research
Inner Ear Damage by Firecracker Trauma
In conclusion, most firecrackers exhibited noise levels #x3e; 110 dB SPL even at a distance of 6 m. This blast injury simultaneously damaged the cochlea, saccule and utricle, but spared the semicircular canals, indicating that blast exposure potentiates the adverse effect of noise exposure on both cochlear and vestibular partitions.Audiol Neurotol 2018;23:116 –121 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - September 11, 2018 Category: Audiology Source Type: research
Evaluation of Hearing and Balance Functions of Patients with Sickle Cell Anemia
Conclusion: While sickle cell anemia causes hearing deficits, it does not have any effect on the central or peripheral vestibular system.Audiol Neurotol 2018;23:122 –125 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - September 11, 2018 Category: Audiology Source Type: research
Minimal Reporting Standards for Active Middle Ear Hearing Implants
There is currently no standardized method for reporting audiological, surgical and subjective outcome measures in clinical trials with active middle ear implants (AMEIs). It is often difficult to compare studies due to data incompatibility and to perform meta-analyses across different centres is almost impossible. A committee of ENT and audiological experts from Germany, Austria and Switzerland decided to address this issue by developing new minimal standards for reporting the outcomes of AMEI clinical trials. The consensus presented here aims to provide a recommendation to enable better inter-study comparability.Audiol Ne...
Source: Audiology and Neurotology - September 7, 2018 Category: Audiology Source Type: research
Hearing Outcomes after Transmastoid Plugging of Superior Canal Dehiscence
Conclusion: The transmastoid plugging of the superior semicircular canal can be performed with an acceptable risk of hearing affection. If the surgery was combined with other techniques, (e.g. endolymphatic sac surgery) then the risk increases.Audiol Neurotol 2018;23:98 –104 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - September 2, 2018 Category: Audiology Source Type: research
Stapes Surgery for Otosclerosis in Patients Presenting with Mixed Hearing Loss
Conclusion: Stapes surgery improved auditory function in patients with mixed hearing loss, allowing most patients to delay the need for an HA without worsening their quality of life.Audiol Neurotol 2018;23:82 –88 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - August 21, 2018 Category: Audiology Source Type: research
A Role for Acoustic Stimulation in Advanced Otosclerosis: Direct Acoustic Cochlear Implant versus Cochlear Implant
This study aims to compare speech perception scores in quiet and noise of 6 DACI and 12 CI patients with advanced otosclerosis at 3 and 12 months after fitting. Preoperative computed tomographic scans of all patients were scored by experts using an existing otosclerosis grading system (stages 1 –3). Speech perception in quiet was significantly better for DACI compared to CI users at 3 months after fitting. At 12 months, no difference was found between DACI and CI patients. Speech perception scores in noise were significantly better in the DACI group. In summary, a DACI system seems to pr ovide an effective treatment opti...
Source: Audiology and Neurotology - August 21, 2018 Category: Audiology Source Type: research
Evaluation of Sustained-Release Steroid Hydrogels in a Guinea Pig Model for Noise-Induced Hearing Loss
The otoprotective effects of thermoreversible poloxamer 407 hydrogels containing dexamethasone or triamcinolone acetonide were evaluated in an animal model of noise-induced hearing loss. Seven days after noise exposure, hearing threshold shifts at 16 kHz were significantly reduced in the 6% dexamethasone group (p #x3c; 0.05). Even though no significant differences in hair cell counts were found, histological analysis revealed a significantly higher spiral ganglion cell density in the first turn of the cochlea in this group (p #x3c; 0.05). No otoprotective effects were observed after the application of the triamcinolone ace...
Source: Audiology and Neurotology - August 9, 2018 Category: Audiology Source Type: research
Cochlear Function in Adults with Epilepsy and Treated with Carbamazepine
Conclusions: Long-term CBZ treatment may result in cochlear dysfunction and auditory deficits.Audiol Neurotol 2018;23:63 –72 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - July 26, 2018 Category: Audiology Source Type: research
Contents Vol. 22, 2017
Audiol Neurotol 2017;22:I –VI (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - July 19, 2018 Category: Audiology Source Type: research
Trough-Shaped Audiograms Are Common in Patients with Acoustic Neuroma and Sudden Sensorineural Hearing Loss
This study suggests that a trough audiogram is a significant finding in patients with sudden-onset sensorineural hearing loss and indicates the presence of acoustic neuroma.Audiol Neurotol 2018;23:58 –62 (Source: Audiology and Neurotology)
Source: Audiology and Neurotology - July 18, 2018 Category: Audiology Source Type: research
