Kidney-Specific Interleukin-17 Responses During Infection and Injury
Annu Rev Immunol. 2023 Oct 31. doi: 10.1146/annurev-immunol-052523-015141. Online ahead of print.ABSTRACTThe kidneys are life-sustaining organs that are vital to removing waste from our body. Because of their anatomic position and high blood flow, the kidneys are vulnerable to damage due to infections and autoinflammatory conditions. Even now, our knowledge of immune responses in the kidney is surprisingly rudimentary. Studying kidney-specific immune events are challenging because of the poor regenerative capacity of the nephrons, accumulation of uremic toxins, and hypoxia- and arterial blood pressure-mediated changes, all...
Source: Annual Review of Immunology - October 31, 2023 Category: Allergy & Immunology Authors: Doureradjou Peroumal Partha S Biswas Source Type: research
Kidney-Specific Interleukin-17 Responses During Infection and Injury
Annu Rev Immunol. 2023 Oct 31. doi: 10.1146/annurev-immunol-052523-015141. Online ahead of print.ABSTRACTThe kidneys are life-sustaining organs that are vital to removing waste from our body. Because of their anatomic position and high blood flow, the kidneys are vulnerable to damage due to infections and autoinflammatory conditions. Even now, our knowledge of immune responses in the kidney is surprisingly rudimentary. Studying kidney-specific immune events are challenging because of the poor regenerative capacity of the nephrons, accumulation of uremic toxins, and hypoxia- and arterial blood pressure-mediated changes, all...
Source: Annual Review of Immunology - October 31, 2023 Category: Allergy & Immunology Authors: Doureradjou Peroumal Partha S Biswas Source Type: research
Kidney-Specific Interleukin-17 Responses During Infection and Injury
Annu Rev Immunol. 2023 Oct 31. doi: 10.1146/annurev-immunol-052523-015141. Online ahead of print.ABSTRACTThe kidneys are life-sustaining organs that are vital to removing waste from our body. Because of their anatomic position and high blood flow, the kidneys are vulnerable to damage due to infections and autoinflammatory conditions. Even now, our knowledge of immune responses in the kidney is surprisingly rudimentary. Studying kidney-specific immune events are challenging because of the poor regenerative capacity of the nephrons, accumulation of uremic toxins, and hypoxia- and arterial blood pressure-mediated changes, all...
Source: Annual Review of Immunology - October 31, 2023 Category: Allergy & Immunology Authors: Doureradjou Peroumal Partha S Biswas Source Type: research
Kidney-Specific Interleukin-17 Responses During Infection and Injury
Annu Rev Immunol. 2023 Oct 31. doi: 10.1146/annurev-immunol-052523-015141. Online ahead of print.ABSTRACTThe kidneys are life-sustaining organs that are vital to removing waste from our body. Because of their anatomic position and high blood flow, the kidneys are vulnerable to damage due to infections and autoinflammatory conditions. Even now, our knowledge of immune responses in the kidney is surprisingly rudimentary. Studying kidney-specific immune events are challenging because of the poor regenerative capacity of the nephrons, accumulation of uremic toxins, and hypoxia- and arterial blood pressure-mediated changes, all...
Source: Annual Review of Immunology - October 31, 2023 Category: Allergy & Immunology Authors: Doureradjou Peroumal Partha S Biswas Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
Immune Responses in Controllers of HIV Infection
Annu Rev Immunol. 2023 Oct 12. doi: 10.1146/annurev-immunol-083122-035233. Online ahead of print.ABSTRACTElite controllers are a heterogeneous group of people living with HIV who control viral replication without antiretroviral therapy. There is substantial evidence that at least some elite controllers are infected with replication-competent virus, thus they may serve as a model of a functional cure of HIV. The mechanisms responsible for virologic control have been actively studied. The most objective data support CD8+ T cell-based mechanisms of control, but other immune responses, mediated by antibodies and natural killer...
Source: Annual Review of Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Abena K Kwaa Joel N Blankson Source Type: research
