New insights in the renal distribution profile of TRPC3 - Of mice and men
Ann Anat. 2023 Nov 15;252:152192. doi: 10.1016/j.aanat.2023.152192. Online ahead of print.ABSTRACTSeveral reports previously investigated the Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects. Nevertheless, the same reports highlighted the potential key-role of TRPC3 in renal disorders. Hence, our interest to inves...
Source: Annals of Anatomy - November 17, 2023 Category: Anatomy Authors: Coline M Diebolt Dirk Schaudien Kerstin Junker Gabriela Krasteva-Christ Thomas Tschernig Colya N Englisch Source Type: research

New insights in the renal distribution profile of TRPC3 - Of mice and men
Ann Anat. 2023 Nov 15;252:152192. doi: 10.1016/j.aanat.2023.152192. Online ahead of print.ABSTRACTSeveral reports previously investigated the Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects. Nevertheless, the same reports highlighted the potential key-role of TRPC3 in renal disorders. Hence, our interest to inves...
Source: Annals of Anatomy - November 17, 2023 Category: Anatomy Authors: Coline M Diebolt Dirk Schaudien Kerstin Junker Gabriela Krasteva-Christ Thomas Tschernig Colya N Englisch Source Type: research

New Insights in the Renal Distribution Profile of TRPC3 - Of Mice and Men
Ann Anat. 2023 Nov 15:152192. doi: 10.1016/j.aanat.2023.152192. Online ahead of print.ABSTRACTSeveral reports previously investigated Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects. Nevertheless, the same reports highlighted the potential key-role of TRPC3 in renal disorders. Hence, our interest to investigate t...
Source: Annals of Anatomy - November 17, 2023 Category: Anatomy Authors: Coline M Diebolt Dirk Schaudien Kerstin Junker Gabriela Krasteva-Christ Thomas Tschernig Colya N Englisch Source Type: research

New Insights in the Renal Distribution Profile of TRPC3 - Of Mice and Men
Ann Anat. 2023 Nov 15:152192. doi: 10.1016/j.aanat.2023.152192. Online ahead of print.ABSTRACTSeveral reports previously investigated Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects. Nevertheless, the same reports highlighted the potential key-role of TRPC3 in renal disorders. Hence, our interest to investigate t...
Source: Annals of Anatomy - November 17, 2023 Category: Anatomy Authors: Coline M Diebolt Dirk Schaudien Kerstin Junker Gabriela Krasteva-Christ Thomas Tschernig Colya N Englisch Source Type: research

New Insights in the Renal Distribution Profile of TRPC3 - Of Mice and Men
Ann Anat. 2023 Nov 15:152192. doi: 10.1016/j.aanat.2023.152192. Online ahead of print.ABSTRACTSeveral reports previously investigated Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects. Nevertheless, the same reports highlighted the potential key-role of TRPC3 in renal disorders. Hence, our interest to investigate t...
Source: Annals of Anatomy - November 17, 2023 Category: Anatomy Authors: Coline M Diebolt Dirk Schaudien Kerstin Junker Gabriela Krasteva-Christ Thomas Tschernig Colya N Englisch Source Type: research

New Insights in the Renal Distribution Profile of TRPC3 - Of Mice and Men
Ann Anat. 2023 Nov 15:152192. doi: 10.1016/j.aanat.2023.152192. Online ahead of print.ABSTRACTSeveral reports previously investigated Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects. Nevertheless, the same reports highlighted the potential key-role of TRPC3 in renal disorders. Hence, our interest to investigate t...
Source: Annals of Anatomy - November 17, 2023 Category: Anatomy Authors: Coline M Diebolt Dirk Schaudien Kerstin Junker Gabriela Krasteva-Christ Thomas Tschernig Colya N Englisch Source Type: research

New Insights in the Renal Distribution Profile of TRPC3 - Of Mice and Men
Ann Anat. 2023 Nov 15:152192. doi: 10.1016/j.aanat.2023.152192. Online ahead of print.ABSTRACTSeveral reports previously investigated Transient Receptor Potential Canonical subfamily channel 3 (TRPC3) in the kidney. However, most of the conclusions are based on animal samples or cell cultures leaving the door open for human tissue investigations. Moreover, results often disagreed among investigators. Histological description is lacking since most of these studies focused on functional aspects. Nevertheless, the same reports highlighted the potential key-role of TRPC3 in renal disorders. Hence, our interest to investigate t...
Source: Annals of Anatomy - November 17, 2023 Category: Anatomy Authors: Coline M Diebolt Dirk Schaudien Kerstin Junker Gabriela Krasteva-Christ Thomas Tschernig Colya N Englisch Source Type: research

3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
Ann Anat. 2023 Nov 7:152185. doi: 10.1016/j.aanat.2023.152185. Online ahead of print.ABSTRACT3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral, stereological, and immunohistochemical analyses were performed. The locomotor activity of the 3-AP-treated rats decreased wher...
Source: Annals of Anatomy - November 9, 2023 Category: Anatomy Authors: Zeynab Ghorbani Mojtaba Sani Zahra Aghighi Meysam Hassani Moghaddam Neda Eskandari Esmaeil Mohammadbagheri Mobina Fathi Zahra Shenasandeh Farid Fotouhi Mohammad-Amin Abdollahifar Mina Salehi Amir-Hossein Bayat Gholam Hossein Meftahi Abbas Aliaghaei Homa R Source Type: research

3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
Ann Anat. 2023 Nov 7:152185. doi: 10.1016/j.aanat.2023.152185. Online ahead of print.ABSTRACT3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral, stereological, and immunohistochemical analyses were performed. The locomotor activity of the 3-AP-treated rats decreased wher...
Source: Annals of Anatomy - November 9, 2023 Category: Anatomy Authors: Zeynab Ghorbani Mojtaba Sani Zahra Aghighi Meysam Hassani Moghaddam Neda Eskandari Esmaeil Mohammadbagheri Mobina Fathi Zahra Shenasandeh Farid Fotouhi Mohammad-Amin Abdollahifar Mina Salehi Amir-Hossein Bayat Gholam Hossein Meftahi Abbas Aliaghaei Homa R Source Type: research

3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
Ann Anat. 2023 Nov 7:152185. doi: 10.1016/j.aanat.2023.152185. Online ahead of print.ABSTRACT3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral, stereological, and immunohistochemical analyses were performed. The locomotor activity of the 3-AP-treated rats decreased wher...
Source: Annals of Anatomy - November 9, 2023 Category: Anatomy Authors: Zeynab Ghorbani Mojtaba Sani Zahra Aghighi Meysam Hassani Moghaddam Neda Eskandari Esmaeil Mohammadbagheri Mobina Fathi Zahra Shenasandeh Farid Fotouhi Mohammad-Amin Abdollahifar Mina Salehi Amir-Hossein Bayat Gholam Hossein Meftahi Abbas Aliaghaei Homa R Source Type: research

3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
Ann Anat. 2023 Nov 7:152185. doi: 10.1016/j.aanat.2023.152185. Online ahead of print.ABSTRACT3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral, stereological, and immunohistochemical analyses were performed. The locomotor activity of the 3-AP-treated rats decreased wher...
Source: Annals of Anatomy - November 9, 2023 Category: Anatomy Authors: Zeynab Ghorbani Mojtaba Sani Zahra Aghighi Meysam Hassani Moghaddam Neda Eskandari Esmaeil Mohammadbagheri Mobina Fathi Zahra Shenasandeh Farid Fotouhi Mohammad-Amin Abdollahifar Mina Salehi Amir-Hossein Bayat Gholam Hossein Meftahi Abbas Aliaghaei Homa R Source Type: research

3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
Ann Anat. 2023 Nov 7:152185. doi: 10.1016/j.aanat.2023.152185. Online ahead of print.ABSTRACT3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral, stereological, and immunohistochemical analyses were performed. The locomotor activity of the 3-AP-treated rats decreased wher...
Source: Annals of Anatomy - November 9, 2023 Category: Anatomy Authors: Zeynab Ghorbani Mojtaba Sani Zahra Aghighi Meysam Hassani Moghaddam Neda Eskandari Esmaeil Mohammadbagheri Mobina Fathi Zahra Shenasandeh Farid Fotouhi Mohammad-Amin Abdollahifar Mina Salehi Amir-Hossein Bayat Gholam Hossein Meftahi Abbas Aliaghaei Homa R Source Type: research

3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
Ann Anat. 2023 Nov 7:152185. doi: 10.1016/j.aanat.2023.152185. Online ahead of print.ABSTRACT3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral, stereological, and immunohistochemical analyses were performed. The locomotor activity of the 3-AP-treated rats decreased wher...
Source: Annals of Anatomy - November 9, 2023 Category: Anatomy Authors: Zeynab Ghorbani Mojtaba Sani Zahra Aghighi Meysam Hassani Moghaddam Neda Eskandari Esmaeil Mohammadbagheri Mobina Fathi Zahra Shenasandeh Farid Fotouhi Mohammad-Amin Abdollahifar Mina Salehi Amir-Hossein Bayat Gholam Hossein Meftahi Abbas Aliaghaei Homa R Source Type: research

3-acetylpyridine induced behavioral dysfunction and neuronal loss in the striatum and hippocampus of adult male rats
Ann Anat. 2023 Nov 7:152185. doi: 10.1016/j.aanat.2023.152185. Online ahead of print.ABSTRACT3-acetylpyridine (3-AP) is a neurotoxin that is known to mainly affect the inferior olivary nucleus (ION) in the brain stem. Although several studies have explored the effect of this neurotoxin, still further investigation is required to understand the impact of this toxin on different parts of the brain. In this research, two groups of rats were studied, the 3-AP-treated and the control groups. Behavioral, stereological, and immunohistochemical analyses were performed. The locomotor activity of the 3-AP-treated rats decreased wher...
Source: Annals of Anatomy - November 9, 2023 Category: Anatomy Authors: Zeynab Ghorbani Mojtaba Sani Zahra Aghighi Meysam Hassani Moghaddam Neda Eskandari Esmaeil Mohammadbagheri Mobina Fathi Zahra Shenasandeh Farid Fotouhi Mohammad-Amin Abdollahifar Mina Salehi Amir-Hossein Bayat Gholam Hossein Meftahi Abbas Aliaghaei Homa R Source Type: research

Interference of MDM2 attenuates vascular endothelial dysfunction in hypertension partly through blocking Notch1/NLRP3 inflammasome pathway
CONCLUSION: In summary, knockdown of MDM2 can attenuate vascular endothelial dysfunction in hypertension, which may be achieved through inhibiting the activation of Notch1 and NLRP3 inflammasome.PMID:37926401 | DOI:10.1016/j.aanat.2023.152183 (Source: Annals of Anatomy)
Source: Annals of Anatomy - November 5, 2023 Category: Anatomy Authors: Rongyan Sun Yubo Zhou Jiao Liang Lihong Yang Zhengjun Fan Huali Wang Source Type: research