When and why was the phrenicoabdominal branch of the left phrenic nerve placed into the esophageal hiatus in German textbooks of anatomy? An anatomical study on 400 specimens reevaluating its course through the diaphragm.
CONCLUSION: The findings on the position of the left phrenicoabdominal branch relative to the diaphragm help to improve topographical knowledge and prevent inadvertent nerve injury during surgical interventions on or near the diaphragm. Further to this, these results may form a substantial basis to adopt the correct description of the passage of the left phrenicoabdominal branch to anatomical textbook knowledge. PMID: 31513915 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - September 9, 2019 Category: Anatomy Authors: Pretterklieber B, Hader M, Hammer N, Pryymachuk G, Pröls F, Vielmuth F, Barnerßoi M, Cotofana S, Custozzo A, Weyers I, Wedel T, Arnold P, Rahner C, Müller-Gerbl M, Pretterklieber ML Tags: Ann Anat Source Type: research

Platysma and the cervical superficial musculoaponeurotic system - Comparative analysis of facial crease and platysmal band development.
CONCLUSIONS: The cervical SMAS (type V) description supports the hypothesis that the SMAS and platysma have different morphological origins. The two different facial and cervical morphological dynamic mimic patterns support the phenotypical difference between facial fold and platysmal band development. PMID: 31499169 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - September 6, 2019 Category: Anatomy Authors: Sandulescu T, Stoltenberg F, Buechner H, Schmidt-Park H, Linnerz F, Jast J, Franzmann M, Blaurock-Sandulescu T, Naumova EA, Arnold WH Tags: Ann Anat Source Type: research

An Update on Endoscopic Mechanical and Powered Dacryocystorhinostomy in Acute Dacryocystitis and Lacrimal Abscess.
Abstract PURPOSE: To provide a brief review of the literature on the utility and outcomes of endoscopic dacryocystorhinostomy (DCR) in patients with acute dacryocystitis (ADC) and lacrimal abscess. METHODS: The authors performed a PubMed search of all articles published in English on endoscopic powered or mechanical DCR performed during the stage of acute dacryocystitis. Data captured include demographics, clinical presentations, time interval to surgery, intraoperative challenges, post-operative course, complications and outcomes. Specific emphasis was laid on addressing the intra-operative challenges and po...
Source: Annals of Anatomy - August 26, 2019 Category: Anatomy Authors: Chong KK, Abdulla HAA, Ali MJ Tags: Ann Anat Source Type: research

Characterisation of flexor digitorum profundus, flexor digitorum superficialis and extensor digitorum communis by electrophoresis and immunohistochemical analysis of myosin heavy chain isoforms in older men.
Abstract INTRODUCTION: Few data exist on the fiber type composition of the extrinsic finger muscles. The aim of the present study was to describe myosin heavy chain (MyHC) composition of flexor digitorum profundus (FDP), flexor digitorum superficialis (FDS) and extensor digitorum communis (EDC). MyHC composition is relevant for whole muscle contractile performance and several studies on single muscle fibers demonstrated that fibers expressing only slow MyHC-1 develop less specific force than fibers expressing fast MyHCs. Since contraction force of finger extensors is smaller than of finger flexors a hypothesis was...
Source: Annals of Anatomy - August 10, 2019 Category: Anatomy Authors: Meznaric M, Čarni A Tags: Ann Anat Source Type: research

Anatomy of the hepatic arteries and their extrahepatic branches in the human liver: A cadaveric study.
CONCLUSIONS: In the present study, an attempt was made to systematically describe the complex hepatic arterial anatomy in a clinically applicable fashion. High variability was seen in the hepatic arterial anatomy at each level, a lot of which could not be included in the current classification systems. The information provided is an important prerequisite for performing accurate intra-arterial hepatic interventions. PMID: 31400446 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - August 7, 2019 Category: Anatomy Authors: Garg S, Kumar KH, Sahni D, Yadav TD, Aggarwal A, Gupta T Tags: Ann Anat Source Type: research

Anatomical feature of knee joint in Aachen minipig as a novel miniature pig line for experimental research in orthopaedics.
CONCLUSIONS: The Aachen minipig reflects porcine anatomical peculiarities, which should be considered, especially for meniscus and ACL reconstruction. PMID: 31394168 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - August 5, 2019 Category: Anatomy Authors: Schulze-Tanzil G, Silawal S, Hoyer M Tags: Ann Anat Source Type: research

Outcome Measures of Facial Nerve Regeneration: A Review of Murine Model Systems.
Abstract Animal models of nerve function have been subject to extensive study in order to understand and investigate methods which may improve axon regeneration and promote functional outcomes following nerve injury and repair. As the facial nerve is a cranial nerve, there is mounting evidence that cranial nerve regeneration differs from peripheral, and outcome models specifically addressing the facial nerve are required. Murine models are the most commonly utilized, with a variety of methods employed to measure the actions of whisking, eye closure, or ear movement as indicators of facial nerve regeneration. Each ...
Source: Annals of Anatomy - August 5, 2019 Category: Anatomy Authors: Chacon MA, Echternacht SR, Leckenby JI Tags: Ann Anat Source Type: research

Volumetric characteristics of prognathic mandible revealed by skeletal unit analysis.
Abstract The purpose of this study was to evaluate the skeletal units of a normal mandible (class I) and a prognathic mandible (class III), to compare the groups, and to investigate the key functional unit responsible for mandibular prognathism. Hemi-mandibles of 101 cases were evaluated by cone-beam computed tomography. Of these, 50 cases had Class I and 51 had Class III mandibles. The length, volume, and volume/length ratio of each skeletal unit were measured. The ratios of the condyle, body unit, and sum of the hemi-mandible between Class I and Class III showed statistically significant results (P
Source: Annals of Anatomy - July 20, 2019 Category: Anatomy Authors: Mun SH, Park M, Lee J, Lim HJ, Kim BC Tags: Ann Anat Source Type: research

Anatomical analyses for maxillary sinus floor augmentation with a lateral approach. A cone beam computed tomography study.
CONCLUSIONS: In conclusion, the analysis of the CBCT before sinus floor elevation allows the identification of anatomical structures and references that might be used for the planning of the surgical approach, aiming to improve the outcome of the treatment and to avoid possible complications. PMID: 31330302 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Kawakami S, Botticelli D, Nakajima Y, Sakuma S, Baba S Tags: Ann Anat Source Type: research

The anterolateral ligament of the knee and the lateral meniscotibial ligament anatomical phantom versus constant structure within the anterolateral complex.
CONCLUSION: Our results show that there is no evidence for the existence of an ALL in human knee joints. It is represented either by the iliotibial tract or-most likely-by the anterior arm of the short head of the biceps femoris muscle. On the other hand, the lmtl was found to be a constantly present structure. PMID: 31330303 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Urban S, Pretterklieber B, Pretterklieber ML Tags: Ann Anat Source Type: research

Age-related changes of the human retinal vessels: possible involvement of lipid peroxidation.
CONCLUSION: This study shows prominent age-related alterations of the pericytes and SMC of retinal vessels. These changes may limit the energy supply to the neurons and be responsible for age-related loss of neurons of the inner retina. PMID: 31330304 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Nag TC, Maurya M, Roy TS Tags: Ann Anat Source Type: research

Morphological Measurements and Classification of the Spinoglenoid Notch: A Three-Dimensional Reconstruction of Computed Tomography in the Chinese Population.
CONCLUSIONS: These morphological measurements of the SGN may help to improve the diagnosis and successful treatment rate of the surgery for the SN entrapment, but the relative clinical trial is necessary to support it. PMID: 31330305 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Yang J, Feng Q, Wen YL, Fan QH, Luo B, Jia WL, Zhang L Tags: Ann Anat Source Type: research

Terminologia Histologica after more than 10 years: disputable terms which need a wide scientific discussion and recent developments.
V, Musil V, Turyna R, Klein M Abstract At first sight, the issue of morphological terminology may seem as "closed and changeless chapter", as many of the structures within the human body have been known for decades or even centuries. However, the exact opposite is true. The initial knowledge of the microscopic structure of the human body has been continuously broadening thanks to the development of new specialized staining techniques, discovery of the electron microscope, or later application of histochemical and immunohistochemical methods into routine tissue examination. Contrary to popular belief, his...
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Varga I, Gálfiová P, Blanková A, Konarik M, Báča V, Dvořákova V, Musil V, Turyna R, Klein M Tags: Ann Anat Source Type: research

Osteocyte numbers decrease only in postcranial but not in cranial bones in humans of advanced age.
CONCLUSIONS: Considering differences and commonalities regarding the bone samples, such as loading, mechanisms of ossification or the surrounding stromal cell compartment, our findings indicate that positional information laid down during ontogenetic processes is instructive during the entire life thus potentially also moulding spatial-specific mechanistic distinctions of bone aging. PMID: 31330307 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Stigler RG, Becker K, Hasanov E, Hörmann R, Gassner R, Lepperdinger G Tags: Ann Anat Source Type: research

Implication of the inferolateral trunk of the cavernous internal artery in cranial nerves blood supply: anatomical study and review of the literature.
This study has demonstrated that there are anastomoses between these branches and arteries arising from the external carotid. This study explains why the sacrifice of a branch of the ILT does not implicate cranial nerve palsy. PMID: 31330308 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Salaud C, Decante C, Ploteau S, Hamel A Tags: Ann Anat Source Type: research

Distribution of glutamate receptor, ionotropic, kainate 1 and neuropeptide calcitonin gene-related peptide mRNAs during formation of the embryonic and postnatal mouse molar in the maxilla.
PMID: 31330309 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Sunohara M, Kamata H, Maeda Y, Miwa Y, Karibe H, Sato I Tags: Ann Anat Source Type: research

Wnt/ β-catenin signaling was activated in supporting cells during exposure of the zebrafish lateral line to cisplatin.
Wnt/β-catenin signaling was activated in supporting cells during exposure of the zebrafish lateral line to cisplatin. Ann Anat. 2019 Jul 19;: Authors: Mi XX, Yan J, Li Y, Shi JP Abstract Zebrafish lateral line neuromasts are composed of central hair cells surrounded by supporting cells. Cisplatin is a common anticancer drug, with hair cell disruption being a frequent side effect of this drug. In our study, we observed complete functional hair cell loss after six hours of cisplatin insult in neuromasts, as demonstrated by anti-parvalbumin 3 immunofluorescence staining or YO-PRO1 vital dye staining...
Source: Annals of Anatomy - July 19, 2019 Category: Anatomy Authors: Mi XX, Yan J, Li Y, Shi JP Tags: Ann Anat Source Type: research

The vasa vasorum reaches deep into the human thoracic aorta.
HJ Abstract Only limited data are available on the extent of the vasa vasorum of the human thoracic aorta, although this could be important with regard to certain pathophysiological states, i.e. aortic aneurysm or atherosclerosis. A preliminary investigation shows that the vascularization of the human thoracic aorta reaches deeper layers than generally believed. PMID: 31288081 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 6, 2019 Category: Anatomy Authors: Federspiel JM, Tschernig T, Laschke MW, Wagenpfeil S, Schnabel P, Schäfers HJ Tags: Ann Anat Source Type: research

Exploration of peripancreatic lymphatic pathways in a live porcine model.
Abstract Pancreatic cancer is associated with a poor prognosis, mainly due to lymph node invasion and lymph node recurrence after surgical resection, even after extended lymphadenectomy. The peripancreatic lymphatic system is highly complex and the specific lymphatic drainage of each part of the pancreas has not been established. The aim of this study was to determine the lymphatic drainage pathways specific to each part of the pancreas on live pigs using Patent Blue. The pancreases of 14 live pigs were injected in different parts of the gland. The technique was efficient and reproducible. The diffusion patterns w...
Source: Annals of Anatomy - July 5, 2019 Category: Anatomy Authors: Renard Y, Perrenot C, Labrousse M, Avisse C, Rhaiem R, Piardi T, Braun M, Perez M Tags: Ann Anat Source Type: research

Vascular access animal models used in research.
CONCLUSIONS: Large animal models are best for haemodynamic shear stress studies and in vivo evaluation of new synthetic vascular grafts. Small animal models, especially the genetically manipulated ones, are ideal for analysis of molecular and cellular pathomechanisms. The selection of animal species to be used depends on the addressed research question. PMID: 31279868 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 4, 2019 Category: Anatomy Authors: Kokozidou M, Katsargyris A, Verhoeven ELG, Schulze-Tanzil G Tags: Ann Anat Source Type: research

Intussusceptive lymphangiogenesis in the sinuses of developing human foetal lymph nodes.
In conclusion, intussusception participates in the formation of the meshwork of processes in LN sinuses during LN development. This mechanism is also of interest because it contributes to the general knowledge of intussusceptive lymphangiogenesis (which has received less attention than intussusception in blood vessels), provides a basis for further studies and supports a new role for vessel intussusception (formation of an intraluminal meshwork with known action in fluid filtering, cell interactions and immunology). PMID: 31279869 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - July 4, 2019 Category: Anatomy Authors: Díaz-Flores L, Gutiérrez R, Pino García M, González-Gómez M, Díaz-Flores L, Carrasco JL Tags: Ann Anat Source Type: research

The application of casein phosphopeptide and amorphous calcium phosphate with fluoride (CPP-ACPF) for restoring mineral loss after dental bleaching with hydrogen or carbamide peroxide: An in-vitro study.
ner L Abstract OBJECTIVE: To conduct an in vitro evaluation of the effect of casein-phosphopeptide and amorphous calcium phosphate with fluoride [CPP-ACPF] upon the calcium [Ca] and phosphorus [P] composition and morphology of dental enamel and dentin after the application of two bleaching agents: 37.5% hydrogen peroxide [HP]) and 35% carbamide peroxide [CP]. MATERIALS AND METHODS: The crowns of 40 extracted human teeth were divided into four groups (n = 10 each). The crowns were sectioned along the cervical-incisal axis, and each half was embedded in acrylic resin, leaving a window 3 mm ...
Source: Annals of Anatomy - July 1, 2019 Category: Anatomy Authors: Llena C, Esteve I, Rodríguez-Lozano FJ, Forner L Tags: Ann Anat Source Type: research

Craniofacial abnormalities in a murine model of Saethre-Chotzen Syndrome.
Abstract BACKGROUND: Saethre-Chotzen Syndrome (SCS) is an autosomal dominant syndrome that occurs due to a mutation or deletion of theTwist-related 1 (Twist1) gene at chromosome 7p21. Our aim was to conduct a morphometric analysis of the craniofacial features in the mouse associated with a Twist1+/- mutation. METHODS: Micro-computed imaging was conducted for the skulls of forty skeletally mature mice, equally distributed by sex (male and female) and two genotypes (Twist1+/- or murine model of SCS; and Twist1+/+ or wild-type). A morphometric analysis was carried out for eight parameters for the maxillary-zygom...
Source: Annals of Anatomy - June 11, 2019 Category: Anatomy Authors: Lonsdale S, Yong R, Khominsky A, Mihailidis S, Townsend G, Ranjitkar S, Anderson PJ Tags: Ann Anat Source Type: research

Neurological Structures and Mediators of Pain Sensation in Anterior Cruciate Ligament Reconstruction.
Abstract Anterior cruciate ligament (ACL) tears is a devastating injury and one of the most common knee injuries experienced by athletes in the United States. Although patients reach maximal subjective improvement by one-year following ACL reconstruction, many patients often experience moderate to severe post-operative pain. Opioids, intra-articular injections, and regional anesthesia have been previously implemented to mediate post-operative pain. However, chronic opioid usage has become an epidemic in the United States. Alternative analgesic modalities, such as nerve blocks, have been implemented in clinical pra...
Source: Annals of Anatomy - June 10, 2019 Category: Anatomy Authors: Hong AJ, Agarwalla A, Liu JN, Gowd AK, McMillan S, Sethi PM, Amin NH Tags: Ann Anat Source Type: research

How to visualize the innervation pattern in tendons: A methodical guide.
CONCLUSION: For the orthopedic community our approach might be a convenient research tool to simultaneously utilize multiple neuronal markers on the same tissue section and to define with greater accuracy the heterogeneity of tendon innervation. PMID: 31195096 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - June 10, 2019 Category: Anatomy Authors: Blumer R, Boesmueller S, Gesslbauer B, Hirtler L, Bormann D, Streicher J, Mittermayr R Tags: Ann Anat Source Type: research

The Dentomaxillary Apparatus from Molecular Biology to Variational Anatomy-underpinning interdisciplinary research.
Abstract Over the past decades, the research environment in Anatomy has dramatically changed. Studies have become more interdisciplinary and complex, with many components required, from basic to clinical research. Within this framework, this special issue was designed to create a link between fundamental fields such as developmental and molecular biology, dental materials, anatomy, histology, and their applications in the clinical research of the dentomaxillary apparatus. PMID: 31154003 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - May 30, 2019 Category: Anatomy Authors: Didilescu AC, Martinez-Sanz E Tags: Ann Anat Source Type: research

Holding donated human bodies in conservation: A novel interactive safe-keeping system meeting high ethical- and safety standards.
Abstract "Mortui vivos docent". Learning from donated bodies is widely considered a corner stone in pre-clinical education, advanced clinical training, and scientific progress in medicine. Making such use of dead human bodies must, of course, accord with high ethical standards and legal constraints. Piety and respect towards donors require using their remains (i) for valuable purposes, (ii) with what we call 'practical decency', (iii) in an efficient way, and (iv) with the utmost safety for all parties involved. With regard to these goals, practical aspects of preservation, safekeeping procedures (for up...
Source: Annals of Anatomy - May 21, 2019 Category: Anatomy Authors: Schnittler H, Ortmann U, Washausen S, Knabe W, Wesemann F, Triphaus S, Schoene-Seifert B Tags: Ann Anat Source Type: research

Anatomy, immunohistochemistry, and numerical distribution of human splenic microvessels.
Abstract The microvascular architecture of the spleen plays an important role in the immunological function of this organ. The different types of vessels are related to different reticular cells each with their own immunomodulatory functions. The present study describes an immunohistochemical and morphometric analysis of the various types of vessels in 21 human autopsy non-pathological splenic samples. On an area of 785,656.37 μm2 for each sample, we classified and quantified the type and number of vascular structures, each according to their morphology and immunohistochemical profile, and obtained the r...
Source: Annals of Anatomy - May 20, 2019 Category: Anatomy Authors: Almenar S, Rios-Navarro C, Ortega M, Molina P, Ferrandez-Izquierdo A, Ruiz-Sauri A Tags: Ann Anat Source Type: research

The ultrastructural anatomy of the nuclear envelope in the masseter muscle indicates its role in the metabolism of the intracellular Ca+.
Abstract Specific ultrastructural anatomy of masticatory muscles is commonly referred to as general pattern assigned to striated muscles. Junctional feet consisting of calcium channels of the sarcoplasmic reticulum (i.e. the ryanodine receptors, RyRs) physically connected to the calcium channels of the t-tubules build triads within striated muscles. Functional RyRs were demonstrated in the nuclear envelopes of pancreas and of a skeletal muscle derived cell line, but not in muscle in situ. It was hypothesized that ryanodine receptors (RyRs) could also exist in the nuclear envelope in the masseter muscle, thus aimin...
Source: Annals of Anatomy - May 19, 2019 Category: Anatomy Authors: Rusu MC, Nicolescu MI, Jianu AM, Mănoiu VS, Ilie AC, Dincă D Tags: Ann Anat Source Type: research

Effect of Aspartame on the Placenta of Adult Albino Rat. A Histological and Immunohistochemical Study.
Abstract Aspartame is an artificial sweetener usually consumed by hundreds of millions of persons all over the world. Its metabolites can be toxic to many organs and there are only a few studies on the use of aspartame during gestation. The present study was designed to fully evaluate the effect of aspartame on the histological structure of the placenta in the adult albino rat. Twenty pregnant female rats were equally divided into group I that served as control, and group II that received aspartame at a dose 14 mg/kg by gavage on the 9th, 10th and 11th day of pregnancy. Placental specimens were processed fo...
Source: Annals of Anatomy - May 17, 2019 Category: Anatomy Authors: Shalaby AM, Ibrahim MAAH, Aboregela AM Tags: Ann Anat Source Type: research

Modulatory effect of empagliflozin on cellular parameters of endocrine pancreas in experimental pre-diabetes.
Abstract The effect of empagliflozin (EMPA), a sodium-glucose cotransporter 2 inhibitor (SGLT2i), on the structure of endocrine pancreas in pre-diabetes (Pre-DM) is not yet elucidated. In the current study the relatively enlarged islets of Langerhans seen in the Pre-DM group was restored to control size by administration of EMPA. In addition the disbalance in the percentage of β-cells and α-cells in islets of the Pre-DM was corrected in the Pre-DM + EMPA group with reversal of the significantly increased islet mass, β-cell mass and neogenesis. Administrating EMPA in Pre-DM decreased l...
Source: Annals of Anatomy - May 17, 2019 Category: Anatomy Authors: Abdel-Hamid AAM, Firgany AEL Tags: Ann Anat Source Type: research

Minimal invasive plating of distal radius fractures. A safe procedure?
CONCLUSIONS: Insertion of volar radius plates through a MIPO approach can be easily accomplished without detachment and damage to the PQ muscle even with grossly adapted implants. However, perfectly pre-shaped plates which are adapted to all anatomic aspects of the distal radius metaphysis are required to achieve optimal contact with the metaphyseal bone and to avoid potential complications. PMID: 31108191 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - May 17, 2019 Category: Anatomy Authors: Neubauer T, Plecko M, Grechenig S, Hartmann A, Ortmaier R, Hitzl W, Feigl G Tags: Ann Anat Source Type: research

Lycopene protects against renal cortical damage induced by nandrolone decanoate in adult male rats.
In conclusion, these results showed that nandrolone decanoate induced toxic effects in the kidney of rats and lycopene had protective effects versus such evoked renal damage. PMID: 31108192 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - May 17, 2019 Category: Anatomy Authors: Shalaby AM, El Shaer DF Tags: Ann Anat Source Type: research

Punctal agenesis: Embryology, presentation, management modalities and outcomes.
Abstract Punctal agenesis is defined as the absence of the punctum occurring secondary to a failure of embryogenesis. This review synthesizes existing data on the embryology, anatomy, clinical presentation, symptomatology, management options and treatment outcomes of punctal agenesis. A foundational knowledge of the underlying embryologic and anatomical abnormalities is fundamental to understanding its clinical presentation and assists in choosing an appropriate management strategy. Existing outcomes data is generally favorable and suggests management with a step-wise approach can alleviate symptoms in patients ac...
Source: Annals of Anatomy - May 15, 2019 Category: Anatomy Authors: Dohlman JC, Habib LA, Freitag SK Tags: Ann Anat Source Type: research

Amygdalin (Vitamin B17) pretreatment attenuates experimentally induced acute autoimmune hepatitis through reduction of CD4+ cell infiltration.
CONCLUSION: AIH induced CD4+ cells infiltration in the liver with subsequent liver tissue damage. Amg. pretreatment inhibited CD4+ cell infiltration and protected the liver tissue. This finding suggests that Amg. could be a therapeutic agent in the management of AIH. PMID: 31100343 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - May 14, 2019 Category: Anatomy Authors: Elsaed WM Tags: Ann Anat Source Type: research

☆This paper belongs to the special issue Lacrimal drainage system.A Major Review on Disorders of the Animal Lacrimal Drainage Systems: Evolutionary Perspectives and Comparisons with Humans.
CONCLUSION: The lacrimal drainage system is an ancestral feature in tetrapod vertebrates and it is present, in some form or another, in most descendant species. The lacrimal drainage system has evolved considerably, adapting to the needs of the species. It is essential to understand the lacrimal drainage disorders of domestic animals so that the animal and human lacrimal sciences contribute more meaningfully to each other. PMID: 31071433 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - May 6, 2019 Category: Anatomy Authors: Ali MJ, Paulsen F Tags: Ann Anat Source Type: research

Advantages and disadvantages of implant navigation surgery. A systematic review.
ng HL Abstract This review elucidates the advantages and disadvantages of the different implant navigation methods to assist the precise surgical placement of dental implants. Implant navigation surgery can be classified into: dynamic and static navigation, and static navigation can further be divided into full (FG)- and half-guided (HG) implant surgery. The HG implant placement includes the drilling-guided, pilot-drill guided, and the non-computed guided approaches. In dynamic navigation, the bone drilling and the implant placement are completely tracked with a specific software; while the static navigation refer...
Source: Annals of Anatomy - May 4, 2019 Category: Anatomy Authors: Gargallo-Albiol J, Barootchi S, Salomó-Coll O, Wang HL Tags: Ann Anat Source Type: research

A comparative study of the epiligament of the medial collateral and the anterior cruciate ligament in the human knee. Immunohistochemical analysis of collagen type I and V and procollagen type III.
CONCLUSIONS: The results of our study illustrate for the first time that fibroblasts in the human epiligament are indeed responsible for the synthesis of the main types of collagen participating in the early ligament healing, thus corresponding to previous data of the medial collateral ligament healing in animal models. The differences between the epiligament of the investigated ligaments could add a novel explanation for the failed anterior cruciate ligament healing. PMID: 31022516 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 22, 2019 Category: Anatomy Authors: Georgiev GP, Kotov G, Iliev A, Slavchev S, Ovtscharoff W, Landzhov B Tags: Ann Anat Source Type: research

The stability of different housekeeping genes in human periodontal ligament cells under inflammatory conditions.
CONCLUSIONS: Reference validation is mandatory for RT-qPCR analyses in new experimental designs. Here, only three genes out of 32 turned out to be appropriate candidates. Due to low CT values and stability, 18S and MT-APT6 are most valid genes for data normalization in experiments with PDL cells under inflammatory conditions and are recommended as standards under these premises. PMID: 31022517 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 22, 2019 Category: Anatomy Authors: Setiawan M, Jäger A, Konermann A Tags: Ann Anat Source Type: research

How many cell types form the epithelial lining of the human uterine tubes? Revision of the histological nomenclature of the human tubal epithelium.
CONCLUSIONS: We recommend replacing the term "epitheliocytus tubarius basalis" in the Terminologia Histologica with the term "lymphocytus T intraepithelialis tubarius", which represents intraepithelial memory T-cells (CD8+, CD45RO+) of the uterine tube. Additionally, we propose that intercalary/peg cells are actively dividing cells, instead of effete or degenerating cells. Finally, the histological nomenclature should be corrected in a way that peg/intercalary cells are not considered synonymous terms for secretory cells. PMID: 31009685 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 19, 2019 Category: Anatomy Authors: Varga I, Miko M, Kachlík D, Žišková M, Danihel Ľ, Babál P Tags: Ann Anat Source Type: research

Influence of fixation method and duration of archiving on immunohistochemical staining intensity in embryonic and fetal tissues.
CONCLUSION: To the best of our knowledge, the influence that the duration of tissue block archiving has on IHC positivity in human embryo and fetal tissue material has not yet been studied. Although the causes of the IHC positivity decline in archived tissue blocks are not well understood, a possible decrease in IHC over time should be considered, particularly in retrospective studies. PMID: 31005572 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 18, 2019 Category: Anatomy Authors: Tauber Z, Stetkova I, Cizkova K Tags: Ann Anat Source Type: research

Class i and class ii small leucine-rich proteoglycans in human cutaneous pacinian corpuscles.
CLASS I AND CLASS II SMALL LEUCINE-RICH PROTEOGLYCANS IN HUMAN CUTANEOUS PACINIAN CORPUSCLES. Ann Anat. 2019 Apr 18;: Authors: García-Piqueras J, García-Mesa Y, Feito J, García B, Quiros LM, Martín-Biedma B, Cobo T, Vega JA, García-Suárez O Abstract Pacinian corpuscles are onion bulb-like multilayered mechanoreceptors that consist of a complicated structure of axon terminals, Schwann related cells (inner core), endoneural related cells (intermediate layer) and perineurial related cells (outer core-capsule). The cells forming those compartments are continuous a...
Source: Annals of Anatomy - April 18, 2019 Category: Anatomy Authors: García-Piqueras J, García-Mesa Y, Feito J, García B, Quiros LM, Martín-Biedma B, Cobo T, Vega JA, García-Suárez O Tags: Ann Anat Source Type: research

Improvement of anatomical knowledge and surgical skills in head and neck region - An interdisciplinary hands-on course for clinical students.
e I Abstract INTRODUCTION: Anatomical knowledge and manual skills are required for every surgical procedure. During the regular study the students only have few opportunities to practice their surgical skills actively. To improve this situation, an interdisciplinary hands-on-course for head and neck anatomy and surgery has been set up at the RWTH Aachen University. MATERIALS UND METHODS: The new course has been devised for one week with a full-time schedule. A special anatomical region has been studied each day. After an anatomical lecture, dissections under tutorial instructions took place. According to the ...
Source: Annals of Anatomy - April 15, 2019 Category: Anatomy Authors: Bock A, Modabber A, Hölzle F, Prescher A, Classen-Linke I Tags: Ann Anat Source Type: research

Dacryocystography: From Theory to Current Practice.
CONCLUSION: Various forms of DCGs can provide additional information to evaluate patients with maxillo-facial trauma, functional epiphora, suspected lacrimal sac diverticula, partial nasolacrimal duct obstruction, and lacrimal drainage tumors. Canaliculi and the membranous part of the nasolacrimal duct are not yet visualized in detail and further focused studies with advanced techniques are required. PMID: 30954539 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 4, 2019 Category: Anatomy Authors: Singh S, Ali MJ, Paulsen F Tags: Ann Anat Source Type: research

Anatomical Considerations in Endoscopic Lacrimal Surgery.
CONCLUSION: A good understanding of the anatomy of the lacrimal drainage system and the lateral wall of the nose will increase the likelihood of successful surgery and minimize the risk of complications and damage to neighbouring structures such as the orbit and skull base. PMID: 30953809 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 3, 2019 Category: Anatomy Authors: Rajak SN, Psaltis AJ Tags: Ann Anat Source Type: research

Computed Tomographic Assessment of the Lacrimal Sac Fossa in the Japanese Population.
CONCLUSIONS: In Japanese patients, the proportion of the lacrimal bone on the lacrimal sac fossa tended to be of greater proportion compared to studies done on other races. The mean angle of the lacrimal sac fossa seemed to be comparatively high. These results indicate that performing an osteotomy during dacryocystorhinostomy could be relatively easier in the Japanese population compared to other races. PMID: 30953810 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 3, 2019 Category: Anatomy Authors: Sarbajna T, Takahashi Y, Valencia MRP, Ito M, Nishimura K, Kakizaki H Tags: Ann Anat Source Type: research

Bone and soft tissue palatal morphology and potential anchorage sides in cleft palate patients.
CONCLUSION: The results suggest that the favorable region for orthodontic MI placement is in the similar anatomical region compared to non-cleft patients, but differs from one side in each group. In unilateral cleft palate patients, the highest bone level was found on the anterior palate side opposite to the cleft side, indicating the most effective region for MIs placement. PMID: 30953811 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 3, 2019 Category: Anatomy Authors: Moscarino S, Scholz J, Bastian A, Knaup I, Wolf M Tags: Ann Anat Source Type: research

Focused Practice of Lacrimal Drainage Disorders.
PMID: 30953812 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 3, 2019 Category: Anatomy Authors: Ali MJ, Paulsen F Tags: Ann Anat Source Type: research

Nazi victims on the dissection table - the Anatomical Institute in Innsbruck.
This study is based on an analysis of the Innsbruck Anatomical Institute's unusually detailed records and numerous documents from various archives, including files pertaining to an inquiry into the institute held after the war by the French occupation authorities. PMID: 30946885 [PubMed - as supplied by publisher] (Source: Annals of Anatomy)
Source: Annals of Anatomy - April 1, 2019 Category: Anatomy Authors: Czech H, Brenner E Tags: Ann Anat Source Type: research

Flap valve of the heart foramen ovale revisited: macroscopic and histologic observations of human near-term fetuses.
te;zquez JF Abstract We assessed the flap valve of the foramen ovale (FO valve) by examining 30 hearts from human fetuses of gestational age 30 to 40 weeks. We dissected the hearts, examined their macroscopic morphology, and then prepared semiserial sagittal sections across the valve. Although the primary septum is expected to extend along the left atrial face, eight hearts had a superior rim of the fossa ovalis on the left atrial face that was too thick and high, so there was no smooth continuation with the valve. Moreover, three of these eight hearts each had a flap valve that was fused with a long and narrow pl...
Source: Annals of Anatomy - April 1, 2019 Category: Anatomy Authors: Suzuki D, Kim JH, Shibata SI, Abe H, Murakami G, Rodríguez-Vázquez JF Tags: Ann Anat Source Type: research