Brain tumours: non-invasive techniques to treat invasive pathologies
Ann Pharm Fr. 2023 Oct 20:S0003-4509(23)00131-1. doi: 10.1016/j.pharma.2023.10.004. Online ahead of print.ABSTRACTBrain and other central nervous system tumours are cancers of poor prognosis, for which current therapeutic possibilities do not match the expectations regarding a curative objective. If the treatment of central nervous system tumours is so difficult, it is partly due to the blood-brain barrier and the blood-tumour barrier, which need to be crossed to access the tumour. Driven by these insufficient results, more and more techniques and technologies are being explored and are evolving: progress of surgery and ra...
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Mathis Barbotin Vincent Thoreau Guyl ène Page Source Type: research

D-optimal mixture design inspired modified release tablet formulation of lamotrigine for the treatment of seizures: An in-depth characterization
CONCLUSION: Based on the optimized formulation consisting of SD of LTG with Eudragit RL, Eudragit RS and PVP K-30, the release rate was consistently similar throughout the GI tract, regardless of the pH of the environment.PMID:37866637 | DOI:10.1016/j.pharma.2023.10.005 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Umesh Atneriya Jitendra Sainy Vijay R Chidrawar Mayank Sharma Rahul Maheshwari Source Type: research

Stability Indicating RP-HPLC-DAD method for simultaneous estimation of Tadalafil and Macitentan in synthetic mixture for treatment of Pulmonary Arterial Hypertension
CONCLUSION: The developed RP-HPLC method was found to be suitable for the determination of both the drugs.PMID:37866638 | DOI:10.1016/j.pharma.2023.10.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Dhruvanshi Gol Amitkumar Vyas Nilam Visana Ajay Patel Sunny Shah Devang Sheth Sandip Dholakia Source Type: research

Brain tumours: non-invasive techniques to treat invasive pathologies
Ann Pharm Fr. 2023 Oct 20:S0003-4509(23)00131-1. doi: 10.1016/j.pharma.2023.10.004. Online ahead of print.ABSTRACTBrain and other central nervous system tumours are cancers of poor prognosis, for which current therapeutic possibilities do not match the expectations regarding a curative objective. If the treatment of central nervous system tumours is so difficult, it is partly due to the blood-brain barrier and the blood-tumour barrier, which need to be crossed to access the tumour. Driven by these insufficient results, more and more techniques and technologies are being explored and are evolving: progress of surgery and ra...
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Mathis Barbotin Vincent Thoreau Guyl ène Page Source Type: research

D-optimal mixture design inspired modified release tablet formulation of lamotrigine for the treatment of seizures: An in-depth characterization
CONCLUSION: Based on the optimized formulation consisting of SD of LTG with Eudragit RL, Eudragit RS and PVP K-30, the release rate was consistently similar throughout the GI tract, regardless of the pH of the environment.PMID:37866637 | DOI:10.1016/j.pharma.2023.10.005 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Umesh Atneriya Jitendra Sainy Vijay R Chidrawar Mayank Sharma Rahul Maheshwari Source Type: research

Stability Indicating RP-HPLC-DAD method for simultaneous estimation of Tadalafil and Macitentan in synthetic mixture for treatment of Pulmonary Arterial Hypertension
CONCLUSION: The developed RP-HPLC method was found to be suitable for the determination of both the drugs.PMID:37866638 | DOI:10.1016/j.pharma.2023.10.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Dhruvanshi Gol Amitkumar Vyas Nilam Visana Ajay Patel Sunny Shah Devang Sheth Sandip Dholakia Source Type: research

Brain tumours: non-invasive techniques to treat invasive pathologies
Ann Pharm Fr. 2023 Oct 20:S0003-4509(23)00131-1. doi: 10.1016/j.pharma.2023.10.004. Online ahead of print.ABSTRACTBrain and other central nervous system tumours are cancers of poor prognosis, for which current therapeutic possibilities do not match the expectations regarding a curative objective. If the treatment of central nervous system tumours is so difficult, it is partly due to the blood-brain barrier and the blood-tumour barrier, which need to be crossed to access the tumour. Driven by these insufficient results, more and more techniques and technologies are being explored and are evolving: progress of surgery and ra...
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Mathis Barbotin Vincent Thoreau Guyl ène Page Source Type: research

D-optimal mixture design inspired modified release tablet formulation of lamotrigine for the treatment of seizures: An in-depth characterization
CONCLUSION: Based on the optimized formulation consisting of SD of LTG with Eudragit RL, Eudragit RS and PVP K-30, the release rate was consistently similar throughout the GI tract, regardless of the pH of the environment.PMID:37866637 | DOI:10.1016/j.pharma.2023.10.005 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Umesh Atneriya Jitendra Sainy Vijay R Chidrawar Mayank Sharma Rahul Maheshwari Source Type: research

Stability Indicating RP-HPLC-DAD method for simultaneous estimation of Tadalafil and Macitentan in synthetic mixture for treatment of Pulmonary Arterial Hypertension
CONCLUSION: The developed RP-HPLC method was found to be suitable for the determination of both the drugs.PMID:37866638 | DOI:10.1016/j.pharma.2023.10.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Dhruvanshi Gol Amitkumar Vyas Nilam Visana Ajay Patel Sunny Shah Devang Sheth Sandip Dholakia Source Type: research

Brain tumours: non-invasive techniques to treat invasive pathologies
Ann Pharm Fr. 2023 Oct 20:S0003-4509(23)00131-1. doi: 10.1016/j.pharma.2023.10.004. Online ahead of print.ABSTRACTBrain and other central nervous system tumours are cancers of poor prognosis, for which current therapeutic possibilities do not match the expectations regarding a curative objective. If the treatment of central nervous system tumours is so difficult, it is partly due to the blood-brain barrier and the blood-tumour barrier, which need to be crossed to access the tumour. Driven by these insufficient results, more and more techniques and technologies are being explored and are evolving: progress of surgery and ra...
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Mathis Barbotin Vincent Thoreau Guyl ène Page Source Type: research

D-optimal mixture design inspired modified release tablet formulation of lamotrigine for the treatment of seizures: An in-depth characterization
CONCLUSION: Based on the optimized formulation consisting of SD of LTG with Eudragit RL, Eudragit RS and PVP K-30, the release rate was consistently similar throughout the GI tract, regardless of the pH of the environment.PMID:37866637 | DOI:10.1016/j.pharma.2023.10.005 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Umesh Atneriya Jitendra Sainy Vijay R Chidrawar Mayank Sharma Rahul Maheshwari Source Type: research

Stability Indicating RP-HPLC-DAD method for simultaneous estimation of Tadalafil and Macitentan in synthetic mixture for treatment of Pulmonary Arterial Hypertension
CONCLUSION: The developed RP-HPLC method was found to be suitable for the determination of both the drugs.PMID:37866638 | DOI:10.1016/j.pharma.2023.10.006 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Dhruvanshi Gol Amitkumar Vyas Nilam Visana Ajay Patel Sunny Shah Devang Sheth Sandip Dholakia Source Type: research

Solubility Enhancement of Fexofenadine using Self-Nano emulsifying Drug Delivery System for improved biomimetic attributes
Conclusion: Thus, the investigation revealed that, the L-SNEDDs incorporated fexofenadine was most effective with a mixture of surfactant and co-surfactant with improved solubility intend to relieve pain associated with inflammation with single-dose oral administration.PMID:37832935 | DOI:10.1016/j.pharma.2023.10.003 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 13, 2023 Category: Drugs & Pharmacology Authors: Popat Mohite Anjali Joshi Sudarshan Singh Bhupendra Prajapati Source Type: research

Solubility Enhancement of Fexofenadine using Self-Nano emulsifying Drug Delivery System for improved biomimetic attributes
Conclusion: Thus, the investigation revealed that, the L-SNEDDs incorporated fexofenadine was most effective with a mixture of surfactant and co-surfactant with improved solubility intend to relieve pain associated with inflammation with single-dose oral administration.PMID:37832935 | DOI:10.1016/j.pharma.2023.10.003 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 13, 2023 Category: Drugs & Pharmacology Authors: Popat Mohite Anjali Joshi Sudarshan Singh Bhupendra Prajapati Source Type: research

Solubility Enhancement of Fexofenadine using Self-Nano emulsifying Drug Delivery System for improved biomimetic attributes
Conclusion: Thus, the investigation revealed that, the L-SNEDDs incorporated fexofenadine was most effective with a mixture of surfactant and co-surfactant with improved solubility intend to relieve pain associated with inflammation with single-dose oral administration.PMID:37832935 | DOI:10.1016/j.pharma.2023.10.003 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - October 13, 2023 Category: Drugs & Pharmacology Authors: Popat Mohite Anjali Joshi Sudarshan Singh Bhupendra Prajapati Source Type: research