D-optimal mixture design inspired modified release tablet formulation of lamotrigine for the treatment of seizures: An in-depth characterization

CONCLUSION: Based on the optimized formulation consisting of SD of LTG with Eudragit RL, Eudragit RS and PVP K-30, the release rate was consistently similar throughout the GI tract, regardless of the pH of the environment.PMID:37866637 | DOI:10.1016/j.pharma.2023.10.005

Source: Annales Pharmaceutiques Francaises - October 22, 2023 Category: Drugs & Pharmacology Authors: Umesh Atneriya Jitendra Sainy Vijay R Chidrawar Mayank Sharma Rahul Maheshwari Source Type: research