Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Detection of estradiol with a digital immunoassay using an anti-immunocomplex antibody and single-molecule observation of gold nanoparticles
In this study, with the aim of small molecule detection, we developed a digital immunoassay method using an anti-immunocomplex antibody that specifically recognizes immunocomplexes of small molecules with antibodies. The number of AuNPs modified with anti-immunocomplex antibody bound to immunocomplex of estradiol and anti-estradiol antibody was counted at a single nanoparticle level using DFM. We demonstrated for the first time that estradiol molecule can be detected by digital immunoassay using DFM and an anti-immunocomplex antibody with a detection sensitivity of 1 pg/mL.PMID:38424409 | DOI:10.1007/s44211-024-00518-6 (So...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - February 29, 2024 Category: Chemistry Authors: Yu Muto Gen Hirao Tamotsu Zako Source Type: research

Assessment of the structural change of DNA by binding with a small molecule based on capillary sieving electrophoresis
In this study, capillary sieving electrophoresis (CSE) using polymer solutions was used to evaluate the structural changes in nucleic acids upon complexation with small molecules. As the model target and nucleic acids, L-tyrosinamide (Tyr-Am) and its aptamer, which is a type of DNA specifically binding to Tyr-Am, were selected. CSE was conducted using a capillary filled with background solution (BGS) containing hydroxypropyl cellulose (HPC) as a sieving matrix. When Tyr-Am or tyrosine was added to the BGS in CSE, the ratio of mobility differences of the Tyr-Am-aptamer complex increased compared to that of the free aptamer ...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - February 27, 2024 Category: Chemistry Authors: Masahide Wada Tatsuro Endo Hideaki Hisamoto Kenji Sueyoshi Source Type: research

Nanomaterial-based sensors in analytical chemistry
Anal Sci. 2024 Mar;40(3):357-358. doi: 10.1007/s44211-023-00498-z.NO ABSTRACTPMID:38403796 | DOI:10.1007/s44211-023-00498-z (Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry)
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - February 25, 2024 Category: Chemistry Authors: Taisuke Shimada Source Type: research

Removal of arsenic(V) using pure zeolite (PZ) and activated dithizone zeolite (ADZ) from aqueous liquids: application to green analytical chemistry
This study highlights the potential of zeolites as outstanding adsorbents for removing arsenic(V) from aqueous solutions. The calculated maximum adsorption capacity (qmax) of pure zeolite and activated dithizone zeolite was 18.2 and 21.1(mg/g), respectively, with R2 = 0.999. According to Freundlich's linear model, the experimental isothermal data indicated that activated dithizone zeolite has a higher value of kf constant and a lower value of the 1/n constant than that obtained for pure zeolite. These results imply favorable adsorption of arsenic(V) on activated dithizone zeolite.PMID:38379121 | DOI:10.1007/s44211-024-0050...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - February 21, 2024 Category: Chemistry Authors: Hossam F Nassar Mahmoud A Mohamed Source Type: research

Absorption-based colorimetric detection of nickel(II) ion by phase separation of thermoresponsive magnetic nanoparticles under microflow
In this study, we demonstrated the detection of nickel(II) ions by the magnetic separation of TMNP induced by their phase transition under microflow. The NTA-tagged TMNP solution mixed with a Ni2+ sample was introduced into a microchannel with a well structure. Moreover, the sample was heated to induce the thermally induced aggregation of TMNP. The Ni-capturing TMNP were trapped in the well by magnetic fields. The supernatant was removed from the outlet, and a dimethylglyoxime (DMG) solution was introduced into the device for colorimetric detection in the well. Because DMG has a higher stability constant with Ni2+, sensiti...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - February 21, 2024 Category: Chemistry Authors: Ren Sasaki Arinori Inagawa Xiaomao Xie Noriyuki Ohnishi Nobuo Uehara Source Type: research

Fourier transform infrared spectroscopy and machine learning for Porphyromonas gingivalis detection in oral bacteria
Anal Sci. 2024 Feb 20. doi: 10.1007/s44211-023-00501-7. Online ahead of print.ABSTRACTPorphyromonas gingivalis, a Gram-negative anaerobic bacillus, is the primary pathogen in periodontitis. Herein, we cultivated strains of oral bacteria, including P. gingivalis and the oral commensal bacteria Actinomyces viscosus and Streptococcus mutans, and recorded the infrared absorption spectra of the gases released by the cultured bacteria at a resolution of 0.5 cm-1 within the wavenumber range of 500-7500 cm-1. From these spectra, we identified the infrared wavenumbers associated with characteristic absorptions in the gases released...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - February 20, 2024 Category: Chemistry Authors: Tomomi Kaneda Masahiro Watanabe Hidehiko Honda Masato Yamamoto Takae Inagaki Shouji Hironaka Source Type: research

Pesticide residue detection technology for herbal medicine: current status, challenges, and prospects
Anal Sci. 2024 Feb 17. doi: 10.1007/s44211-024-00515-9. Online ahead of print.ABSTRACTThe domains of cancer therapy, disease prevention, and health care greatly benefit from the use of herbal medicine. Herbal medicine has become the mainstay of developing characteristic agriculture in the planting area increasing year by year. One of the most significant factors in affecting the quality of herbal medicines is the pesticide residue problem caused by pesticide abuse during the cultivation of herbal medicines. It is urgent to solve the problem of detecting pesticide residues in herbal medicines efficiently and rapidly. In thi...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - February 17, 2024 Category: Chemistry Authors: Bin Peng Yueliang Xie Qingfu Lai Wen Liu Xuelan Ye Li Yin Wanxin Zhang Suqin Xiong Heng Wang Hui Chen Source Type: research