Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Elemental analysis of hourly collected air filters with X-ray fluorescence under grazing incidence
Anal Sci. 2023 Dec 25. doi: 10.1007/s44211-023-00483-6. Online ahead of print.ABSTRACTThe X-ray fluorescence under grazing incidence condition (XRF-UGI) was applied for the direct analysis of aerosol filters. Particulate matter less than 2.5 microns (PM2.5) was collected hourly on polytetrafluoroethylene filters using a continuous PM monitor with a virtual impactor method. Although the sampling mass is in trace amounts of 5-30 μg, the metallic contents, such as V, Cr, Mn, Fe, Zn, and Pb, can be measured at sub-ng m-3 detection limits. The effects of the non-uniformity and poor flatness of the PM filters were discussed wit...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 24, 2023 Category: Chemistry Authors: Hikari Takahara Atsushi Morikawa Saori Kitayama Tsugufumi Matsuyama Kouichi Tsuji Source Type: research

High-pH mobile phase in reversed-phase liquid chromatography-tandem mass spectrometry to improve the separation efficiency of aminoglycoside isomers
In this study, a highly basic mobile phase (pH > 11), which is not typically employed for reversed-phase liquid chromatography (RPLC), was utilized in RPLC-tandem mass spectrometry (MS/MS) to achieve effective separation between electrically neutral bases of aminoglycosides (AGs). A mixture of AGs was simultaneously analyzed using 500 mmol L-1 ammonia aqueous solution (pH 11.8) as the mobile phase. A total of 11 AGs, including 2 stereoisomers of neomycin (B and C) and 5 structurally similar components of gentamicin (C1, C1a, C2, C2a, and C2b), were completely separated for the first time. The high separation performance...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 23, 2023 Category: Chemistry Authors: Yuta Nakano Hiroshi Sakamaki Yuiko Tasaki-Handa Shingo Saito Source Type: research

Simplified capture, extraction, and amplification of cellular DNA from water samples
In this study, a simplified pre-treatment method for analyzing DNA in water samples was evaluated. The process consists of filtration, DNA extraction, and amplification, which can be achieved within a short time. In the filtration process, two types of filters, firstly a tissue paper (Kimwipe) and then a glass filter (GF/F), were used in sequence. The first large pore size filter enabled a reduction in filtration time by removing large particulate matter impurities present in river water matrix. Cells spiked into 1 L of river water were recovered at more than 90% within approximately 5 min filtration time. Also, DNA was ex...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 23, 2023 Category: Chemistry Authors: Mai Kawaguchi Hiroshi Aoki Hiroki Kamo Kazuki Miura Yuki Hiruta Siro Simizu Daniel Citterio Source Type: research

Confocal micro-X-ray fluorescence analysis for difference identification of ceramic samples
Anal Sci. 2023 Dec 22. doi: 10.1007/s44211-023-00464-9. Online ahead of print.ABSTRACTA nondestructive analytical method for difference identification is required in the research fields such as forensic science or archeology. An X-ray fluorescence (XRF) analysis is one of feasible techniques for this purpose. Micro-XRF using an X-ray micro-beam gives elemental distributions by scanning the samples. A confocal micro-XRF (CM-XRF) technique is a unique analytical technique to analyze limited volume. CM-XRF enables elemental depth imaging and elemental profiling in depth nondestructively. Therefore, CM-XRF has been applied for...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 22, 2023 Category: Chemistry Authors: Kazuaki Mori Takayuki Hourai Tsugufumi Matsuyama Shangjun Zhuo Kouichi Tsuji Source Type: research

Ratio-fluorescent and naked-eye visualized dual-channel sensing strategy for Cu < sup > 2+ < /sup > and alkaline phosphatase activity assay
Anal Sci. 2023 Dec 21. doi: 10.1007/s44211-023-00479-2. Online ahead of print.ABSTRACTThe levels of Cu2+ and alkaline phosphatase (ALP) are the important indicators of the developed stage of the relative diseases. Herein, a binary ratio-fluorescent and smartphone-assisted visual strategy basing on 4'-aminomethyl-4, 5', 8-trimethylpsoralen (AMT) and the oxidation of o-phenylenediamine was developed. Under the action of Cu2+, the fluorescent molecule, 3-diaminophenazine (DAP) formed which can act as a fluorescent acceptor of the ratio-fluorescent sensor. The emission spectrum of AMT overlapped with the excitation spectrum of...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 21, 2023 Category: Chemistry Authors: Jing Zhu Xinyu Li Source Type: research

Comparison of 3-nitrophenylhydrazine, O-benzyl hydroxylamine, and 2-picolylamine derivatizations for analysis of short-chain fatty acids through liquid chromatography coupled with tandem mass spectrometry
Anal Sci. 2023 Dec 19. doi: 10.1007/s44211-023-00474-7. Online ahead of print.ABSTRACTShort-chain fatty acids (SCFAs) are metabolites derived from gut microbiota and implicated in host homeostasis. Hence, the profiling SCFAs from biological samples plays an important role in revealing the interaction between gut microbiota and pathogens. Previous studies, liquid chromatography-tandem mass spectrometry (LC-MS/MS) combined with various derivatization strategies have been performed to obtain the SCFA profiles from biological samples. However, it is poor evidence to compare these derivatization regents and conditions. Thus, we...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 19, 2023 Category: Chemistry Authors: Ryosuke Nagatomo Aoi Ichikawa Haruki Kaneko Koichi Inoue Source Type: research

Targeted-activation superparamagnetic spherical nucleic acid nanomachine for ultrasensitive SERS detection of lysozyme based on a bienzymatic-mediated in situ amplification strategy
Anal Sci. 2023 Dec 19. doi: 10.1007/s44211-023-00471-w. Online ahead of print.ABSTRACTLysozyme (LYS) is a widely used bacteriostatic enzyme. In this paper, we built a sensitive and accurate Raman biosensing platform to detect trace amounts of LYS. The method is based on magnetic spherical nucleic acid formed by a combination of LYS aptamer (Apt) and magnetic beads (MBs). Meanwhile, this method utilizes a dual enzyme-assisted nucleic acid amplification circuit and surface-enhanced Raman scattering (SERS). In this sensing strategy, which is based on the specific recognition of Apt, magnetic spherical nucleic acids were assoc...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 19, 2023 Category: Chemistry Authors: Yang Xu Yue Liu Yu Luo Xinlin Xu Yingying Li Lin Zhao Tiantian Li Yan Zhang Peng He Xiaoming Mou Source Type: research

Validation of spectrophotometric and colorimetric methods to quantify clindamycin in skin tissue: application to in vitro release and ex vivo dermatokinetic studies from separable effervescent microarray patch loaded bacterially sensitive microparticle
Anal Sci. 2023 Dec 19. doi: 10.1007/s44211-023-00478-3. Online ahead of print.ABSTRACTDiabetes mellitus can cause diabetic foot infection (DFI) complications. DFI is generally caused by infection from bacteria and Methicillin-Resistant Staphylococcus aureus (MRSA) which is resistant to several antibiotics. Application therapy of clindamycin (CLY) administration with the oral route has low bioavailability and non-selective distribution of antibiotics towards bacteria intravenously. In this research, CLY was developed into bacterially sensitive microparticles (MPs) which were further incorporated into a separable effervescen...
Source: Analytical Sciences : the international journal of the Japan Society for Analytical Chemistry - December 19, 2023 Category: Chemistry Authors: Iis Nurul Rahmadani Nurul Fauziah Muhammad Nur Hidayat Nur Annisa Safirah Nur Azizah Fadhilah Andi Dian Permana Source Type: research