Transient Hemi-Lower Limb Ischemia in the Newborn: Arterial Thrombosis or Persistent Sciatic Artery?
AJP Rep 2017; 07: e13-e16 DOI: 10.1055/s-0037-1598044Neonatal thromboembolism occurs with various predispositions and triggers. Early diagnosis of the thrombosis is challenging and essential for the therapeutic interventions. We herein report two newborns who presented with transient hemi-lower limb ischemia due to (1) arterial thrombosis or (2) a persistent sciatic artery (PSA). The patient with arterial thrombosis showed elevations of fibrin degradation product and D-dimer and received antithrombin and heparin intravenously. The patient with PSA was immediately assessed by a contrast-enhanced computed tomography because ...
Source: American Journal of Perinatology Reports - February 10, 2017 Category: Perinatology & Neonatology Authors: Kirino, Makiko Ochiai, Masayuki Ichiyama, Masako Inoue, Hirosuke Kusuda, Takeshi Kinjo, Tadamune Ishimura, Masataka Ohga, Shouichi Tags: Case Report Source Type: research

Epstein –Barr Virus-Induced Mononucleosis as an Imitator of Severe Preeclampsia
Conclusion Acute infection with EBV should be included in the differential diagnosis of preeclampsia with severe features, particularly in the setting of fever. Supportive treatment and observation may prevent iatrogenic preterm birth. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - February 10, 2017 Category: Perinatology & Neonatology Authors: Staley, S. Allison Smid, Marcela C. Dotters-Katz, Sarah K. Stringer, Elizabeth M. Tags: Case Report Source Type: research

Serial Measurement of Superior Vena Cava Flow in Evaluation of the Clinical Severity of Pial Arteriovenous Fistula in an Infant
Conclusion SVC flow reflects the shunt volume and may be a useful parameter for evaluating the optimal timing and effectiveness of intervention in pial AVF. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - January 30, 2017 Category: Perinatology & Neonatology Authors: Ago, Mako Masumoto, Kenichi Uchiyama, Atsushi Aihara, Yasuo Okada, Yoshikazu Kusuda, Satoshi Tags: Case Report Source Type: research

Placenta Percreta and Incomplete Uterine Rupture after Endometrial Ablation and Tubal Occlusion
We report a case of pregnancy conceived contemporaneously with endometrial ablation and tubal occlusion. Diagnosis of pregnancy was delayed due to low suspicion. Complications included cervical implantation and placenta percreta, necessitating hysterectomy with the fetus in situ. Intraoperatively, incomplete uterine rupture was noted. Abnormal neovascularization, fibrous adhesions, and anatomical distortion necessitated a complex surgical approach. Women undergoing endometrial ablation must be thoroughly counseled about the serious risks of postablation pregnancy, the need for contraception, and the risk of sterilization f...
Source: American Journal of Perinatology Reports - December 30, 2016 Category: Perinatology & Neonatology Authors: Kohn, Jaden R. Popek, Edwina Diaz-Arrastia, Concepcion R. Guan, Xiaoming Shamshirsaz, Alireza A. Belfort, Michael A. Fox, Karin A. Tags: Case Report Source Type: research

Secondary Postpartum Hemorrhage due to Spontaneous Uterine Artery Rupture after Normal Vaginal Delivery Managed by Selective Arterial Embolization
We present a case of spontaneous rupture of the uterine artery following a normal vaginal delivery with a delayed presentation, which resulted in significant morbidity. This case discusses the presentation and management of this rare obstetrical emergency. The report also discusses the role of selective arterial embolization in management of secondary postpartum hemorrhage. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - December 30, 2016 Category: Perinatology & Neonatology Authors: Thakur, Mili Adekola, Henry O. Asaad, Radwan Gonik, Bernard Tags: Case Report Source Type: research

Placental microRNA Expression Is Not Altered by Maternal Obesity and Fetal Overgrowth
AJP Rep 2016; 06: e430-e435 DOI: 10.1055/s-0036-1597652 Objective The epigenetic mechanisms underlying fetal metabolic programming are poorly understood. We studied whether obesity is associated with alterations in placental miRNA expression. Study Design A cross-sectional study was performed, including (1) normal-weight women (BMI 20–24.9 kg/m2) and normal-birth-weight (BW) infants (2,700–3,500 g) (n = 20), (2) normal-weight and macrosomic infants (BW ≥ 4,000 g) (n = 10), (3) obese (BMI ≥ 35 kg/m2) and normal BW infants (n =&t...
Source: American Journal of Perinatology Reports - December 30, 2016 Category: Perinatology & Neonatology Authors: Ghaffari, Neda Parry, Samuel Elovitz, Michal A. Durnwald, Celeste P. Tags: Case Report Source Type: research

Gastric Rupture in Pregnancy: Case Series from a Tertiary Institution in Rwanda and Review of the Literature
Conclusion We report the management and outcome of three cases of pregnancy-related gastric rupture. To our knowledge, these three cases represent the largest series of pregnancy-related gastric ruptures from a single institution. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - December 28, 2016 Category: Perinatology & Neonatology Authors: Ntirushwa, David Rulisa, Stephen Muhorakeye, Febronie Bazzett-Matabele, Lisa Rurangwa, Theogene Small, Maria Tags: Case Report Source Type: research

Early Postnatal Seizures in a Neonate with Wolf –Hirschhorn Syndrome
Conclusion Neonatal seizures with WHS occur rarely. This is the first case report on seizures just after birth in a neonate with WHS. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - December 12, 2016 Category: Perinatology & Neonatology Authors: Go, Hayato Haneda, Kentaro Maeda, Hajime Ogasawara, Kei Imamura, Takashi Momoi, Nobuo Hosoya, Mitsuaki Tags: Case Report Source Type: research

Placental Abruption Revealed by Hemoperitoneum: A Case Report
Conclusion Hemoperitoneum in pregnant women with no other signs can reveal placental abruption. The difficulty in identifying the cause may delay appropriate management. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - December 12, 2016 Category: Perinatology & Neonatology Authors: Bertholdt, C. Vincent-Rohfritsch, A. Tsatsaris, V. Goffinet, F. Tags: Case Report Source Type: research

Could High Volume of Physical Activities in Early Pregnancy Interfere with Deep Placentation?
Conclusion This small case series suggest that high PA volume in first trimester could interfere with deep placentation. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - December 5, 2016 Category: Perinatology & Neonatology Authors: Vachon-Marceau, Chantale Girard, Mario Bisson, Mich èle Demers, Suzanne Marc, Isabelle Bujold, Emmanuel Tags: Case Report Source Type: research

Adenovirus and “Culture-Negative Sepsis” in a Preterm Neonate
Conclusion As the ability to diagnosis respiratory viral infections in the NICU has improved greatly with the use of PCR testing, the impact and contribution of these viruses to neonatal disease is now being recognized and the notion of “culture-negative” sepsis needs reassessment. The diagnosis of these infections in high risk infants is important not only for etiologic and epidemiologic reasons but ultimately for informing antimicrobial stewardship efforts. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Ab...
Source: American Journal of Perinatology Reports - December 5, 2016 Category: Perinatology & Neonatology Authors: Moallem, Mohannad Song, Eunkyung Jaggi, Preeti Conces, Miriam R. Kajon, Adriana E. S ánchez, Pablo J. Tags: Case Report Source Type: research

Clinical and Cost Impact Analysis of a Novel Prognostic Test for Early Detection of Preterm Birth
The objective of this study was to evaluate the potential impact to the U.S. health care system by adopting a novel test that identifies women at risk for spontaneous preterm birth. Methods A decision-analytic model was developed to assess clinical and cost outcomes over a 1-year period. The use of a prognostic test to predict spontaneous preterm birth in a hypothetical population of women reflective of the U.S. population (predictive arm) was compared with the current baseline rate of spontaneous preterm birth and associated infant morbidity and mortality (baseline care arm). Results In a population of 3,5...
Source: American Journal of Perinatology Reports - December 1, 2016 Category: Perinatology & Neonatology Authors: Caughey, Aaron B. Zupancic, John A. F. Greenberg, James M. Garfield, Susan S. Thung, Stephen F. Iams, Jay D. Tags: Case Report Source Type: research

Patient Perception of Negative Noninvasive Prenatal Testing Results
AJP Rep 2016; 06: e391-e406 DOI: 10.1055/s-0036-1594243 Objective To determine patient perception of residual risk after receiving a negative non-invasive prenatal testing result. Introduction Recent technological advances have yielded a new method of prenatal screening, non-invasive prenatal testing (NIPT), which uses cell-free fetal DNA from the mother's blood to assess for aneuploidy. NIPT has much higher detection rates and positive predictive values than previous methods however, NIPT is not diagnostic. Past studies have demonstrated that patients may underestimate the limitations of prenatal screening...
Source: American Journal of Perinatology Reports - November 28, 2016 Category: Perinatology & Neonatology Authors: Wittman, A. Theresa Hashmi, S. Shahrukh Mendez-Figueroa, Hector Nassef, Salma Stevens, Blair Singletary, Claire N. Tags: Case Report Source Type: research

Naloxone and Metabolites Quantification in Cord Blood of Prenatally Exposed Newborns and Correlations with Maternal Concentrations
AJP Rep 2016; 06: e385-e390 DOI: 10.1055/s-0036-1593993 Objective To quantify naloxone and metabolite concentrations in newborns prenatally exposed to sublingual buprenorphine/naloxone and to correlate neonatal and maternal metabolite concentrations. Methods This is a prospective observational cohort study. Eleven pregnant women treated for opioid use disorder with sublingual buprenorphine/naloxone were enrolled. Maternal and newborn blood was collected and analyzed for naloxone, buprenorphine, and metabolites via liquid chromatography tandem mass spectrometry. Descriptive statistics and correlation coeffic...
Source: American Journal of Perinatology Reports - November 23, 2016 Category: Perinatology & Neonatology Authors: Wiegand, Samantha L. Swortwood, Madeleine J. Huestis, Marilyn A. Thorp, John Jones, Hendre é E. Vora, Neeta L. Tags: Case Report Source Type: research

Erratum: Pregnancy Complicated by Gorham –Stout Disease and Refractory Chylothorax
AJP Rep 2016; 06: e384-e384 DOI: 10.1055/s-0036-1593988 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - November 4, 2016 Category: Perinatology & Neonatology Authors: Hellyer, Jessica Oliver-Allen, Hunter Shafiq, Majid Tolani, Alisha Druzin, Maurice Jeng, Michael Rockson, Stanley Lowsky, Robert Tags: Erratum Source Type: research

Standard External Doppler Fetal Heart Tracings versus External Fetal Electrocardiogram in Very Preterm Gestation: A Pilot Study
AJP Rep 2016; 06: e378-e383 DOI: 10.1055/s-0036-1592413 Introduction Very preterm babies can be difficult to monitor using standard external Doppler fetal heart tracings (eFHR). External fetal electrocardiogram (fECG) is a potential alternative. Methods This was a prospective observational pilot study of hospitalized patients at 24 to 28 weeks' gestation. A total of 30 women were traced for up to 2 hours using eFHR followed by up to 2 hours using fECG. The percentage of time the fetal heart rate was traced during the 2-hour window for each modality was calculated. Differences of ≥ 60, ≥ 80, and ≥ 9...
Source: American Journal of Perinatology Reports - November 4, 2016 Category: Perinatology & Neonatology Authors: Fruhman, Gary Gavard, Jeffrey A. McCormick, Kristina Wilson-Griffin, Judy Amon, Erol Gross, Gilad A. Tags: Case Report Source Type: research

Development, Implementation, and Assessment of a Genetics Curriculum Across Institutions
Conclusion This three-module workshop on women's health genetics was easily implemented across institutions and led to increased knowledge. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - November 4, 2016 Category: Perinatology & Neonatology Authors: Dotters-Katz, Sarah Hocutt, Ginger Osborne, C Michael Hardisty, Emily E. Demmer, Laurie Vora, Neeta Tags: Case Report Source Type: research

Propofol-Related Infusion Syndrome in the Peripartum Period
Conclusion PRIS should be included in the differential diagnosis of intubated or postoperative patients in the obstetric population. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - October 12, 2016 Category: Perinatology & Neonatology Authors: Eziefule, Akwugo A. Elshatanoufy, Solafa Thakur, Mili Rocha, Frederico G. Tags: Case Report Source Type: research

Erratum: Clinical Findings and Autopsy of a Preterm Infant with Breast Milk-Acquired Cytomegalovirus Infection
AJP Rep 2016; 06: e367-e367 DOI: 10.1055/s-0036-1593627 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - October 10, 2016 Category: Perinatology & Neonatology Authors: Lopes, Anne-Aur élie Belhabri, Souad Karaoui, Leila Tags: Erratum Source Type: research

Categorizing Fetal Heart Rate Variability with and without Visual Aids
This study examined the ability of clinicians to correctly categorize images of fetal heart rate (FHR) variability with and without the use of exemplars. Study Design A sample of 33 labor and delivery clinicians inspected static FHR images and categorized them into one of four categories defined by the National Institute of Child Health and Human Development (NICHD) based on the amount of variability within absent, minimal, moderate, or marked ranges. Participants took part in three conditions: two in which they used exemplars representing FHR variability near the center or near the boundaries of each range, and a ...
Source: American Journal of Perinatology Reports - October 6, 2016 Category: Perinatology & Neonatology Authors: Ashdown, Amanda J. Scerbo, Mark W. Belfore, Lee A. Davis, Stephen S. Abuhamad, Alfred Z. Tags: Case Report Source Type: research

Pregnancy Complicated by Gorham –Stout Disease and Refractory Chylothorax
Discussion This case illustrates the management of a rare clinical disease of bone resorption and lymphangiomatosis complicated by bilateral, refractory chylothoraces, triggered by pregnancy, in whom treatment options are limited, and the need for a multidisciplinary health care team to ensure successful maternal and fetal outcomes. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - October 4, 2016 Category: Perinatology & Neonatology Authors: Hellyer, Jessica Oliver-Allen, Hunter Shafiq, Majid Tolani, Alisha Druzin, Maurice Jeng, Michael Rockson, Stanley Lowsky, Robert Tags: Case Report Source Type: research

Could Revision of the Embryology Influence Our Cesarean Delivery Technique: Towards an Optimized Cesarean Delivery for Universal Use
AJP Rep 2016; 06: e352-e354 DOI: 10.1055/s-0036-1593444Until today, there is no standardized Cesarean Section method and many variations exist. The main variations concern the type of abdominal incision, usage of abdominal packs, suturing the uterus in one or two layers, and suturing the peritoneal layers or leaving them open. One of the questions is the optimal location of opening the uterus. Recently, omission of the bladder flap was recommended. The anatomy and histology as results from the embryological knowledge might help to solve this question. The working thesis is that the higher the incision is done, the more dam...
Source: American Journal of Perinatology Reports - September 30, 2016 Category: Perinatology & Neonatology Authors: Stark, Michael Mynbaev, Ospan Vassilevski, Yuri Rozenberg, Patrick Tags: Perspective Source Type: research

Neonatal Enterovirus Infection: Case Series of Clinical Sepsis and Positive Cerebrospinal Fluid Polymerase Chain Reaction Test with Myocarditis and Cerebral White Matter Injury Complications
Conclusion Neonates who appear septic without bacterial etiology may have EV CNS infections that can be diagnosed rapidly by CSF PCR testing. Cases may be underdiagnosed in the early neonatal period if specific testing is not performed. Neonates with EV infection should be investigated for evidence of periventricular leukomalacia, screened for myocarditis, and considered for IVIG treatment. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journa...
Source: American Journal of Perinatology Reports - September 29, 2016 Category: Perinatology & Neonatology Authors: Morriss, Frank H. Lindower, Julie B. Bartlett, Heather L. Atkins, Dianne L. Kim, Jean O. Klein, Jonathan M. Ford, Bradley A. Tags: Case Report Source Type: research

Chorioamniotic Separation Found on Obstetric Ultrasound and Perinatal Outcome
This study aims to evaluate pregnancy outcomes in patients with spontaneous and iatrogenic chorioamniotic separation diagnosed by ultrasound after 17 weeks. Methods This is a retrospective cohort study of women with a singleton pregnancy who were diagnosed with chorioamniotic separation (n = 106) after 17 weeks' gestation from January 2000 to January 2013. Patients with chorioamniotic separation were compared with a group of patients who had obstetric ultrasounds without a diagnosis of chorioamniotic separation. Those without chorioamniotic separation were matched (1:1) on gestational age on the date ...
Source: American Journal of Perinatology Reports - September 27, 2016 Category: Perinatology & Neonatology Authors: Bibbo, Carolina Little, Sarah E. Bsat, Jad Botka, Kris Ann Benson, Carol B. Robinson, Julian N. Tags: Case Report Source Type: research

Pregnancy-Related Changes of Amino Acid and Acylcarnitine Concentrations: The Impact of Obesity
AJP Rep 2016; 06: e329-e336 DOI: 10.1055/s-0036-1592414 Objective Our primary objective was to assess the difference in amino and fatty acid biomarkers throughout pregnancy in women with and without obesity. Interactions between biomarkers and obesity status for associations with maternal and fetal metabolic measures were secondarily analyzed. Methods Overall 39 women (15 cases, 24 controls) were enrolled in this study during their 15- to 20-weeks' visit at the University of Iowa Hospitals and Clinics. We analyzed 32 amino acid and acylcarnitine concentrations with tandem mass spectrometry for differences t...
Source: American Journal of Perinatology Reports - September 21, 2016 Category: Perinatology & Neonatology Authors: Ryckman, Kelli K. Donovan, Brittney M. Fleener, Diedre K. Bedell, Bruce Borowski, Kristi S. Tags: Case Report Source Type: research

Spontaneous Rectus Sheath Hematoma in Pregnancy Complicated by the Development of Transfusion Related Acute Lung Injury: A Case Report and Review of the Literature
Conclusion Review of the literature demonstrates 13 cases of RSH in pregnancy, including our own. No other cases were complicated by transfusion related morbidity. RSH and TRALI are rare, but life threatening entities that can complicate pregnancy. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 15, 2016 Category: Perinatology & Neonatology Authors: Gibbs, Jennifer Bridges, Firas Trivedi, Kiran Vullo, John Tags: Case Report Source Type: research

Erratum: Congenital Chikungunya Virus Infection after an Outbreak in Salvador, Bahia, Brazil
AJP Rep 2016; 06: e324-e324 DOI: 10.1055/s-0036-1593344 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 13, 2016 Category: Perinatology & Neonatology Authors: Lyra, Priscila Pinheiro Ribeiro Campos, G úbio Soares Bandeira, Igor D órea Sardi, Silvia Ines de Moura Costa, Lilian Ferreira Santos, Fl ávia Rocha Ribeiro, Carlos Alexandre Santos Jardim, Alena Maria Barreto Santiago, Ana Cec ília Travassos de Olive Tags: Erratum Source Type: research

Intrapartum Cervical Laceration and Subsequent Pregnancy Outcomes
In this study, 55 women were confirmed to have a cervical laceration in the first delivery; 43 lacerations after vaginal delivery (VD) and 12 after cesarean delivery (CD). The median gestational age of the first delivery was 400/7 weeks and the median birth weight 3,545 g; these did not differ between VD and CD. In the second pregnancy, 2 of 55 women (4.6%) had a prophylactic cerclage placed; 1 carried to term and the other delivered at 356/7 weeks. In total, four women (9.3%) delivered the second pregnancy 
Source: American Journal of Perinatology Reports - September 9, 2016 Category: Perinatology & Neonatology Authors: Wong, Luchin F. Wilkes, Jacob Korgenski, Kent Varner, Michael W. Manuck, Tracy A. Tags: Case Report Source Type: research

Neurological Outcomes after Human Umbilical Cord Patch for In Utero Spina Bifida Repair in a Sheep Model
Conclusions Cryopreserved HUC patch appears to improve survival and neurological outcome in this severe form of the ovine model of spina bifida. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - September 9, 2016 Category: Perinatology & Neonatology Authors: Papanna, Ramesha Mann, Lovepreet K. Snowise, Saul Morales, Yisel Prabhu, Sanjay P. Tseng, Scheffer C. G. Grill, Raymond Fletcher, Stephen Moise, Kenneth J. Tags: Case Report Source Type: research

Conservative Management and Planned Surgery for Periviable Advanced Extrauterine Abdominal Pregnancy with Favorable Outcome: Report of Two Cases
AJP Rep 2016; 06: e301-e308 DOI: 10.1055/s-0036-1588003Advanced abdominal pregnancy is an extremely rare condition that poses diagnostic and management challenges. A high index of suspicion and careful assessment of the patient's symptoms, supplemented with obstetric ultrasound, and magnetic resonance imaging, are crucial for timely diagnosis and management to prevent life-threatening complications. The presence of periviable fetuses in advanced abdominal pregnancies increases the challenge to achieve a balance between maternal and fetal benefits and risks. Early diagnosis and management decisions via a multidisciplinary a...
Source: American Journal of Perinatology Reports - September 1, 2016 Category: Perinatology & Neonatology Authors: Harirah, Hassan M. Smith, J. Michael Dixon, C. Luke Hankins, Gary D. V. Tags: Case Report Source Type: research

Congenital Chikungunya Virus Infection after an Outbreak in Salvador, Bahia, Brazil
We describe two cases of well-documented congenital CHIKV infection in Salvador-Brazil, where CHIKV has been identified since 2014. The outbreak in the city led to the clinical CHIKV diagnoses of both pregnant women 2 days before delivery. Urine and blood samples from the mothers and newborns were collected and tested for reverse transcription-polymerase chain reaction (PCR) analysis for Zika, dengue, and CHIKV. Both neonates and mothers had positive urine and serum PCR results for CHIKV. The newborns had significant perinatal complications and were admitted to the neonatal intensive care unit. The purpose of our case repo...
Source: American Journal of Perinatology Reports - August 22, 2016 Category: Perinatology & Neonatology Authors: Lyra, Priscila Pinheiro Ribeiro Campos, G úbio Soares Bandeira, Igor D órea Sardi, Silvia Ines Costa, Lilian Ferreira de Moura Santos, Fl ávia Rocha Ribeiro, Carlos Alexandre Santos Jardim, Alena Maria Barreto Santiago, Ana Cec ília Travassos de Olive Tags: Case Report Source Type: research

Influence of Birthweight on the Prospective Stillbirth Risk in the Third Trimester: A Cross-Sectional Cohort Study
The objective of this study was to determine the effect of birthweight on prospective stillbirth risk. Methods Cross-sectional study of singleton births in the United States from 2010 to 2012 from 32 through 42 weeks was conducted. Stillbirth risk was stratified by birthweight and gestational age adjusted for time from death to delivery. The primary outcome was the prospective stillbirth risk for each birthweight category. Student t-test was used for continuous data, chi-square to compare categorical data. Binomial proportions were used to derive prospective and cumulative risks. Cox proportional hazards regression...
Source: American Journal of Perinatology Reports - August 17, 2016 Category: Perinatology & Neonatology Authors: Contag, Stephen Brown, Clayton Crimmins, Sarah Goetzinger, Katherine Tags: Case Report Source Type: research

Acute Myocardial Infarction in the First Trimester of Pregnancy in a Great Grand Multiparous Woman with Poorly Controlled Chronic Hypertension
Conclusion Good pregnancy outcomes are possible after early antepartum MI, especially with early diagnosis, appropriate treatment, and a multidisciplinary team approach to prenatal care. Delivery should occur in a tertiary referral center with experience managing high-risk obstetric patients with cardiac disease. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 16, 2016 Category: Perinatology & Neonatology Authors: Prasannan, Lakha Blitz, Matthew J. Rabin, Jill M. Tags: Case Report Source Type: research

Prophylactic Antibiotics in Twin Pregnancies Complicated by Previable Preterm Premature Rupture of Membranes
Conclusion Currently, even though in singletons with previable PPROM there is a recommendation to consider administrating antibiotics, in the setting of twins, no evidence exists to support this. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 16, 2016 Category: Perinatology & Neonatology Authors: Myrick, Olivia Dotters-Katz, Sarah Grace, Matthew Manuck, Tracy Boggess, Kim Goodnight, William Tags: Case Report Source Type: research

Digoxin Therapy of Fetal Superior Ventricular Tachycardia: Are Digoxin Serum Levels Reliable?
Conclusion We describe an interesting case of digoxin toxicity with cardiac manifestations of digoxin toxicity despite subtherapeutic serum drug levels. This case report emphasizes the significance of instituting an early diagnosis of digoxin toxicity during pregnancy, based not only on serum drug levels but also on clinical presentation. In cases of refractory supportive care, digoxin Fab fragment antibody administration should be considered. With timely diagnosis and treatment, excellent maternal and perinatal outcomes can be achieved. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Artic...
Source: American Journal of Perinatology Reports - August 10, 2016 Category: Perinatology & Neonatology Authors: Saad, Antonio F. Monsivais, Luis Pacheco, Luis D. Tags: Case Report Source Type: research

Effectiveness of Synchronized Noninvasive Ventilation to Prevent Intubation in Preterm Infants
Conclusions The application of SNIPPV in place of or to remove mechanical ventilation avoids intubation in 74.4% of preterm infants with respiratory failure. No adverse effects were detected. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - August 4, 2016 Category: Perinatology & Neonatology Authors: Ramos-Navarro, Cristina Sanchez-Luna, Manuel Sanz-L ópez, Ester Maderuelo-Rodriguez, Elena Zamora-Flores, Elena Tags: Case Report Source Type: research

Infantile Hepatic Hemangioendothelioma: An Uncommon Cause of Persistent Pulmonary Hypertension in a Newborn Infant
We report a 2-day old, full-term infant with multifocal, large infantile hepatic hemangioendothelioma, who presented with an early onset of pulmonary hypertension, managed successfully with supportive care and systemic therapy directed toward the involution of infantile hepatic hemangioendothelioma.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - July 22, 2016 Category: Perinatology & Neonatology Authors: Chatmethakul, Trassanee Bhat, Ramachandra Alkaabi, Maryam Siddiqui, Abdul Peevy, Keith Zayek, Michael Tags: Case Report Source Type: research

Mode of Delivery in Premature Neonates: Does It Matter?
Conclusion In our all-comers cohort, replicative of everyday obstetric practice, CD did not improve neonatal outcomes in preterm infants.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - July 22, 2016 Category: Perinatology & Neonatology Authors: Racusin, Diana A. Antony, Kathleen M. Haase, Jennifer Bondy, Melissa Aagaard, Kjersti M. Tags: Case Report Source Type: research

Bilateral Pulmonary Agenesis: A Rare and Unexpected Finding in a Newborn
Conclusion Autopsy examination revealed bilateral pulmonary agenesis with a short, blindly ending trachea.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 29, 2016 Category: Perinatology & Neonatology Authors: Nguyen, Lananh N.Parks, W. Tony Tags: Case Report Source Type: research

Topical Iodine –Induced Thyrotoxicosis in a Newborn with a Giant Omphalocele
Conclusion This case emphasizes that significant topical iodine exposure can result in both hypothyroidism and hyperthyroidism, and therefore, vigilance in monitoring thyroid function is imperative.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 28, 2016 Category: Perinatology & Neonatology Authors: Malhotra, Sonali Kumta, Shilpa Bhutada, Alok Jacobson-Dickman, Elka Motaghedi, Roja Tags: Case Report Source Type: research

Topical Iodine–Induced Thyrotoxicosis in a Newborn with a Giant Omphalocele
Conclusion This case emphasizes that significant topical iodine exposure can result in both hypothyroidism and hyperthyroidism, and therefore, vigilance in monitoring thyroid function is imperative.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 28, 2016 Category: Perinatology & Neonatology Authors: Malhotra, SonaliKumta, ShilpaBhutada, AlokJacobson-Dickman, ElkaMotaghedi, Roja Tags: Case Report Source Type: research

Magnetic Resonance Imaging Diagnosis of Volvulus through Mesenteric Defect in Neonate
AJP Rep 2016; 06: e239-e242DOI: 10.1055/s-0036-1584548Antenatal midgut volvulus is a rare surgical emergency in which bowel is severely compromised. Rarely the etiology is a mesenteric defect. Early diagnosis is essential and lifesaving in the immediate newborn period. Typically upper gastrointestinal or ultrasound imaging can be suggestive of the diagnosis of volvulus in the neonate. Sometimes, however, the diagnosis may be elusive. Herein, we report on the use of neonatal magnetic resonance imaging to diagnose a midgut volvulus that occurred through a congenital mesenteric defect.[...]Thieme Medical Publishers 333 Sevent...
Source: American Journal of Perinatology Reports - June 28, 2016 Category: Perinatology & Neonatology Authors: Leopold, ScottAl-Qaraghouli, MohammedHussain, NaveedFinck, Christine Tags: Case Report Source Type: research

Patient Counseling and Preferences for Elective Repeat Cesarean Delivery
Conclusion Most women were inadequately counseled about delivery options. The most important factors influencing the choice of ERCD over VBAC were patient preferences, risk for fetal injury, and perceived physician preference.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 14, 2016 Category: Perinatology & Neonatology Authors: Folsom, SusanEsplin, M. SeanEdmunds, SeanMetz, Torri D.Jackson, G. MarcPorter, T. FlintVarner, Michael W. Tags: Case Reports Source Type: research

Are There Head Volume Alterations at 11 to 14 Weeks in Fetuses with Congenital Heart Defects? A First Trimester Case Series
This study aims to assess head volume (HV) alterations at 11 to 14 weeks in fetuses with congenital heart defects (CHD). Methods A retrospective case–control study on 100 normal and 26 CHD fetuses was conducted. The fetuses had a first trimester scan with volume data sets stored from which HV was calculated. The mean HV and HV as a function of crown–rump length (CRL) in normal fetuses were compared with established normograms. Mean HV, HV as a function of CRL, and HV/CRL were compared between normal and CHD fetuses. Nonparametric Kruskal–Wallis H test was used with p 
Source: American Journal of Perinatology Reports - June 14, 2016 Category: Perinatology & Neonatology Authors: Abu-Rustum, Reem S.Ziade, M. FouadAbu-Rustum, Sameer E.Daou, Linda S. Tags: Case Report Source Type: research

Fetoscopic Amniotic Band Release in a Case of Chorioamniotic Separation: An Innovative New Technique
Conclusion In those cases where release of an amniotic band is impossible due to membrane separation, surgery in a CO2-filled uterus offers an option.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 10, 2016 Category: Perinatology & Neonatology Authors: Belfort, Michael A.Whitehead, William E.Ball, RobertSilver, RobertShamshirsaz, AlirezaRuano, RodrigoEspinoza, JimmyBecker, JudithOlutoye, OlutoyinHollier, Larry Tags: Case Report Source Type: research

A Rare Complex Case of Congenital Umbilical Arteriovenous Malformation and Review of Literature
Conclusion To our knowledge, this is the first time that no complete excision was made but only ligation of the arteries. The infant was discharged home on postoperative day 14 being asymptomatic. Follow-up Doppler US showed thrombosed vascular structures.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 9, 2016 Category: Perinatology & Neonatology Authors: Gregorio-Hernández, RebecaSanz-López, EsterHoyo, Alejandra Aguado-DelManrique-Martín, GemaDe-Agustín, Juan CarlosSánchez-Luna, Manuel Tags: Case Report Source Type: research

Conservative Management of Invasive Placentation: Two Cases with Different Surgical Approaches
Conclusion These cases highlight the successful use of conservative management for invasive placentation in two stable patients and showcase the novel use of a robotic-assisted laparoscopic surgery for management of invasive placentation.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 9, 2016 Category: Perinatology & Neonatology Authors: Fay, Emily E.Norquist, BarbaraJolley, JenniferHardesty, Melissa Tags: Case Report Source Type: research

Right Ventricular Myocardial Ischemia with Arrhythmia in an Asphyxiated Newborn
Conclusion MI in the perinatal period in a structurally normal heart is very rare and mortality is high. Although acute treatments extrapolated from adult MI has been described to result in favorable outcomes in newborn infants, guidelines are lacking on how to manage acute MI and associated ventricular arrhythmia.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 7, 2016 Category: Perinatology & Neonatology Authors: Solevåg, Anne LeeSchmölzer, Georg M.Cheung, Po-Yin Source Type: research

The Effect of a Universal Cervical Length Screening Program on Antepartum Management and Birth Outcomes
The objective of this study was to evaluate the effect of a universal cervical length screening program on the incidence of antepartum interventions. Study Design This retrospective cohort study included women delivering ≥ 20 weeks of gestation with singleton pregnancies before and after implementing universal cervical length screening. Antepartum interventions included admission for threatened preterm birth, ≥ 2 cervical length measurements, cervical cerclage, neonatology consultation, betamethasone, antibiotic administration for preterm premature rupture of membranes, and toco...
Source: American Journal of Perinatology Reports - June 7, 2016 Category: Perinatology & Neonatology Authors: Shainker, Scott A.Modest, Anna M.Hacker, Michele R.Ralston, Steven J. Tags: Case Report Source Type: research

Clinical Findings and Autopsy of a Preterm Infant with Breast Milk-Acquired Cytomegalovirus Infection
Conclusion Although rare, postnatal CMV infections transmitted by raw breast milk given to very low-birthweight infants can have dramatic consequences.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 1, 2016 Category: Perinatology & Neonatology Authors: Anne-Aurélie, LopesSouad, BelhabriLeila, Karaoui Tags: Case Report Source Type: research