COVID-19 and HELLP: Overlapping Clinical Pictures in Two Gravid Patients
Conclusion Clinicians are encouraged to consider both of these diagnoses when caring for pregnant women during the COVID-19 pandemic to assure that both maternal and fetal concerns are addressed and treated appropriately. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 17, 2020 Category: Perinatology & Neonatology Authors: Futterman, Itamar Toaff, Miriam Navi, Liel Clare, Camille A. Tags: Case Report Source Type: research

Cell-Free DNA as an Addition to Ultrasound for Screening of a Complete Hydatidiform Mole and Coexisting Normal Fetus Pregnancy: A Case Report
Conclusion In atypical cases, cell-free DNA may be useful in evaluation of molar pregnancy. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - June 17, 2020 Category: Perinatology & Neonatology Authors: Gabra, Martina G. Gonzalez, Maritza G. Bullock, Holly N. Hill, Meghan G. Tags: Case Report Source Type: research

Acute Respiratory Decompensation Requiring Intubation in Pregnant Women with SARS-CoV-2 (COVID-19)
AJP Rep 2020; 10: e169-e175 DOI: 10.1055/s-0040-1712925There is a current paucity of information about the obstetric and perinatal outcomes of pregnant novel coronavirus disease 2019 (COVID-19) patients in North America. Data from China suggest that pregnant women with COVID-19 have favorable maternal and neonatal outcomes, with rare cases of critical illness or respiratory compromise. However, we report two cases of pregnant women diagnosed with COVID-19 in the late preterm period admitted to tertiary care hospitals in New York City for respiratory indications. After presenting with mild symptoms, both quickly developed w...
Source: American Journal of Perinatology Reports - June 3, 2020 Category: Perinatology & Neonatology Authors: Silverstein, Jenna S. Limaye, Meghana A. Brubaker, Sara G. Roman, Ashley S. Bautista, Judita Chervenak, Judith Ratner, Adam J. Sommer, Philip M. Roselli, Nicole M. Gibson, Charlisa D. Ellenberg, David Penfield, Christina A. Tags: Case Report Source Type: research

Heart Failure with Preserved Ejection Fraction in a Postpartum Patient with Superimposed Preeclampsia and COVID-19
We present a case from March 2020 of a 25-year-old G2P2002 whose delivery was complicated by preeclampsia with severe features who presented to the emergency department 9 days after cesarean delivery with chest tightness and dyspnea on exertion. On presentation she had severe hypertension, pulmonary edema, elevated brain natriuretic peptide, and high-sensitivity troponin-I, suggesting a diagnosis of hypertensive emergency leading to heart failure with a preserved ejection fraction resulting in pulmonary edema and abnormal cardiac screening tests. However, bilateral opacities were seen on a computed tomography of the chest,...
Source: American Journal of Perinatology Reports - June 3, 2020 Category: Perinatology & Neonatology Authors: Sinkey, Rachel G. Rajapreyar, Indranee Robbins, Lindsay S. Dionne-Odom, Jodie Pogwizd, Steven M. Casey, Brian M. Tita, Alan T.N. Tags: Case Report Source Type: research

Risk Factors for Postpartum Maternal Infection Following Spontaneous Vaginal Delivery Complicated by Chorioamnionitis
Conclusion Postpartum infections occur in ∼1/15 women delivering vaginally with chorioamnionitis, with those who deliver at < 32 weeks' gestation being at increased risk. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - May 14, 2020 Category: Perinatology & Neonatology Authors: Daifotis, Helen A. Smith, Megan M. Denoble, Anna E. Dotters-Katz, Sarah K. Tags: Case Report Source Type: research

The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia —A Case Series
Conclusion The Carit maneuver is an original and successful intervention in the management of shoulder dystocia unresponsive to McRobert's maneuver and suprapubic pressure. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Gei, Alfredo F Mastache, Jorge Suarez Pacheco, Luis D. Villanueva, Mariana Tags: Original Article Source Type: research

Antibiotic Prophylaxis Trials in Obstetrics: A Call for Pediatric Collaboration
AJP Rep 2020; 10: e155-e158 DOI: 10.1055/s-0040-1709513Surgical site infections are common complications of cesarean delivery. Many recent studies, including meta-analyses, have assessed the efficacy of antibiotic prophylaxis. Those articles have demonstrated that preincision antibiotic prophylaxis reduces the incidence of surgical site infections postcesarean, and that the use of adjunctive azithromycin further reduces infection after nonelective cesarean deliveries. However, long-term effects of fetal exposure to antibiotic prophylaxis—including asthma, obesity, and alterations in microbiota—have also been demonstrat...
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: McLaren, Rodney A. Atallah, Fouad Minkoff, Howard Tags: Case Report Source Type: research

Applying a Prediction Model for Vaginal Birth after Cesarean to a Latina Inner-City Population
Conclusion Our results question whether Latina ethnicity should continue to be considered a negative predictive factor for VBAC success. Our results also suggest that Latinas with a low predicted VBAC success should not necessarily be discouraged from attempting TOLAC. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Nguyen, Michelle T. Hayes-Bautista, Teodocia Maria Hsu, Paul Bragg, Christina Chopin, Irving Shaw, Kathryn J. Tags: Case Report Source Type: research

Perinatal Hypophosphatasia in a Premature Infant
AJP Rep 2020; 10: e139-e147 DOI: 10.1055/s-0040-1709512A premature male infant was delivered at 32 weeks' gestation due to category-2 fetal tracing after preterm labor. The physical exam showed shortened and bowed long bones, with calvarium felt in small area of the head. Serum alkaline phosphatase was very low on admission. Extensive metaphyseal abnormalities, bowing of long bones, and poor ossification of all bones were noted on skeletal survey (radiography). Based on ultrasound evidence of “bowing” and long bone fractures at 26 weeks, amniocentesis was performed that later diagnosed hypophosphatasia by genetic testi...
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Sankaran, Deepika Chandrasekharan, Praveen K. Rawat, Munmun Tags: Case Report Source Type: research

Peritoneovaginal Fistula and Appendicitis-Related Pelvic Abscess in Pregnancy
AJP Rep 2020; 10: e129-e132 DOI: 10.1055/s-0040-1708849Appendicitis in pregnancy is the most common nonobstetric surgical emergency. Pregnancy causes changes in anatomy, which could lead to uncertainty regarding the diagnosis of appendicitis. This case report describes a case of appendicitis presenting with peritoneovaginal fistula in a pregnant woman in the second trimester, with interesting finding of isolated appendiceal endometriosis on pathology. The importance of complete physical examination, including speculum examination, is emphasized in the pregnant patient presenting with acute-onset abdominal pain. Imaging cri...
Source: American Journal of Perinatology Reports - April 14, 2020 Category: Perinatology & Neonatology Authors: Saleh, Mona Kim, Antonia Francis Gardner, Andrew Sun, Katherine Brubaker, Sara Tags: Case Report Source Type: research

Hepatitis C Virus Infection in Children and Pregnant Women: An Updated Review of the Literature on Screening and Treatments
Conclusion To improve public health, universal screening of pregnant women for HCV infection should be performed. Early identification of women and children with HCV infection is important to enable them to be included in assessment and/or treatment programs. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - March 30, 2020 Category: Perinatology & Neonatology Authors: Ragusa, Rosalia Corsaro, Liberato Simone Frazzetto, Evelise Bertino, Emanuele Bellia, Maria Alessandra Bertino, Gaetano Tags: Case Report Source Type: research

Smith –Lemli–Opitz's Syndrome as a Possible Cause of Recurrent Pregnancy Loss: A Case Report
AJP Rep 2020; 10: e118-e120 DOI: 10.1055/s-0040-1705131Based on the known carrier frequency of Smith–Lemli–Opitz's syndrome (SLOS), the prevalence of this disease should be significantly higher than what is observed in the population. This may be due to a higher rate of pregnancy loss in affected embryos. Here, we present the case of a couple who underwent expanded carrier screening (ECS) after experiencing three first trimester pregnancy losses. Both parents were found to be carriers of SLOS mutations, and DNA analysis of the fetal remains of the third loss revealed the aborted fetus had inherited both the maternal an...
Source: American Journal of Perinatology Reports - March 30, 2020 Category: Perinatology & Neonatology Authors: Mitra, Anjali Dolitsky, Shelley Yadava, Stacy Ashkinadze, Elena Tags: Case Report Source Type: research

Unique Clinical and Histological Features of Placental Mesenchymal Dysplasia Complicated by Severe Preeclampsia in the Midtrimester
AJP Rep 2020; 10: e113-e117 DOI: 10.1055/s-0040-1709186Detailed clinical and pathological features of placental mesenchymal dysplasia (PMD) complicated by preeclampsia (PE) are unknown. A 39-year-old nulliparous woman was referred at 19 weeks gestation. Ultrasound examination identified a fetus with severe growth restriction (−2.8 SD) and a markedly thickened placenta with many cystic structures suggestive of PMD. At 21 weeks, the patient developed severe hypertension (180/95 mm Hg) with marked proteinuria and an elevated serum soluble fms-like tyrosine-kinase-1 (sFlt-1) level (47,000 pg/L). The pregnancy was terminate...
Source: American Journal of Perinatology Reports - March 27, 2020 Category: Perinatology & Neonatology Authors: Kuwabara, Yoshimitsu Yonezawa, Mirei Kubota, Yumene Ichikawa, Tomoko Ohashi, Ryuji Takeshita, Toshiyuki Tags: Case Report Source Type: research

Efficacy of Prophylactic Antibiotics in Bakri Intrauterine Balloon Placement: A Single-Center Retrospective Analysis and Literature Review
Conclusion Our protocol might be effective and sufficient in preventing postpartum BIUB placement-related endometritis. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: American Journal of Perinatology Reports)
Source: American Journal of Perinatology Reports - March 18, 2020 Category: Perinatology & Neonatology Authors: Nagase, Yoshikazu Matsuzaki, Shinya Kawanishi, Yoko Nakagawa, Satoshi Kakigano, Aiko Takiuchi, Tsuyoshi Mimura, Kazuya Tomimatsu, Takuji Endo, Masayuki Kimura, Tadashi Tags: Original Article Source Type: research

How Reliable Is a Statewide Prescription Monitoring Program for Identifying Post-Cesarean Opioid Use?
Conclusion Nearly half of women who underwent a cesarean section and who were administered opioids 24 hours prior to discharge did not have a detectable postpartum opioid prescription in the PMP. While identification of prescription filling improved with time, many of women were not detectable in the PMP system. These data call into question the accuracy of PMPs in identifying prescription opioid filling patterns in the postpartum setting. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Am...
Source: American Journal of Perinatology Reports - March 18, 2020 Category: Perinatology & Neonatology Authors: Premkumar, Ashish Speedy, Sedona E. Miller, Emily S. Tags: Original Article Source Type: research