Natural antibodies targeting LPS in pleural effusions of various etiologies
CONCLUSIONS: Our results highlight a potential role of anti-LPS NAbs in the pleural cavity that should be further explored.PMID:38591123 | DOI:10.1152/ajplung.00377.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Ioannis Sarrigeorgiou Erasmia Rouka Ourania S Kotsiou Garyfallia Perlepe Efrosini S Gerovasileiou Konstantinos I Gourgoulianis Peggy Lymberi Sotirios G Zarogiannis Source Type: research
Chronic intermittent hypoxia elicits distinct transcriptomic responses among neurons and oligodendrocytes within the brainstem of mice
Am J Physiol Lung Cell Mol Physiol. 2024 Apr 9. doi: 10.1152/ajplung.00320.2023. Online ahead of print.ABSTRACTChronic intermittent hypoxia (CIH) is a prevalent condition characterized by recurrent episodes of oxygen deprivation, linked to respiratory and neurological disorders. Prolonged CIH is known to have adverse effects, including endothelial dysfunction, chronic inflammation, oxidative stress, and impaired neuronal function. These factors can contribute to serious comorbidities, including metabolic disorders and cardiovascular diseases. To investigate the molecular impact of CIH, we examined male C57BL/6J mice expose...
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Hemalatha Bhagavan Aguan D Wei Luiz M Oliveira Kimberly A Aldinger Jan-Marino Ramirez Source Type: research
Natural antibodies targeting LPS in pleural effusions of various etiologies
CONCLUSIONS: Our results highlight a potential role of anti-LPS NAbs in the pleural cavity that should be further explored.PMID:38591123 | DOI:10.1152/ajplung.00377.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Ioannis Sarrigeorgiou Erasmia Rouka Ourania S Kotsiou Garyfallia Perlepe Efrosini S Gerovasileiou Konstantinos I Gourgoulianis Peggy Lymberi Sotirios G Zarogiannis Source Type: research
Chronic intermittent hypoxia elicits distinct transcriptomic responses among neurons and oligodendrocytes within the brainstem of mice
Am J Physiol Lung Cell Mol Physiol. 2024 Apr 9. doi: 10.1152/ajplung.00320.2023. Online ahead of print.ABSTRACTChronic intermittent hypoxia (CIH) is a prevalent condition characterized by recurrent episodes of oxygen deprivation, linked to respiratory and neurological disorders. Prolonged CIH is known to have adverse effects, including endothelial dysfunction, chronic inflammation, oxidative stress, and impaired neuronal function. These factors can contribute to serious comorbidities, including metabolic disorders and cardiovascular diseases. To investigate the molecular impact of CIH, we examined male C57BL/6J mice expose...
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Hemalatha Bhagavan Aguan D Wei Luiz M Oliveira Kimberly A Aldinger Jan-Marino Ramirez Source Type: research
Natural antibodies targeting LPS in pleural effusions of various etiologies
CONCLUSIONS: Our results highlight a potential role of anti-LPS NAbs in the pleural cavity that should be further explored.PMID:38591123 | DOI:10.1152/ajplung.00377.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Ioannis Sarrigeorgiou Erasmia Rouka Ourania S Kotsiou Garyfallia Perlepe Efrosini S Gerovasileiou Konstantinos I Gourgoulianis Peggy Lymberi Sotirios G Zarogiannis Source Type: research
Chronic intermittent hypoxia elicits distinct transcriptomic responses among neurons and oligodendrocytes within the brainstem of mice
Am J Physiol Lung Cell Mol Physiol. 2024 Apr 9. doi: 10.1152/ajplung.00320.2023. Online ahead of print.ABSTRACTChronic intermittent hypoxia (CIH) is a prevalent condition characterized by recurrent episodes of oxygen deprivation, linked to respiratory and neurological disorders. Prolonged CIH is known to have adverse effects, including endothelial dysfunction, chronic inflammation, oxidative stress, and impaired neuronal function. These factors can contribute to serious comorbidities, including metabolic disorders and cardiovascular diseases. To investigate the molecular impact of CIH, we examined male C57BL/6J mice expose...
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Hemalatha Bhagavan Aguan D Wei Luiz M Oliveira Kimberly A Aldinger Jan-Marino Ramirez Source Type: research
Natural antibodies targeting LPS in pleural effusions of various etiologies
CONCLUSIONS: Our results highlight a potential role of anti-LPS NAbs in the pleural cavity that should be further explored.PMID:38591123 | DOI:10.1152/ajplung.00377.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Ioannis Sarrigeorgiou Erasmia Rouka Ourania S Kotsiou Garyfallia Perlepe Efrosini S Gerovasileiou Konstantinos I Gourgoulianis Peggy Lymberi Sotirios G Zarogiannis Source Type: research
Chronic intermittent hypoxia elicits distinct transcriptomic responses among neurons and oligodendrocytes within the brainstem of mice
Am J Physiol Lung Cell Mol Physiol. 2024 Apr 9. doi: 10.1152/ajplung.00320.2023. Online ahead of print.ABSTRACTChronic intermittent hypoxia (CIH) is a prevalent condition characterized by recurrent episodes of oxygen deprivation, linked to respiratory and neurological disorders. Prolonged CIH is known to have adverse effects, including endothelial dysfunction, chronic inflammation, oxidative stress, and impaired neuronal function. These factors can contribute to serious comorbidities, including metabolic disorders and cardiovascular diseases. To investigate the molecular impact of CIH, we examined male C57BL/6J mice expose...
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Hemalatha Bhagavan Aguan D Wei Luiz M Oliveira Kimberly A Aldinger Jan-Marino Ramirez Source Type: research
Natural antibodies targeting LPS in pleural effusions of various etiologies
CONCLUSIONS: Our results highlight a potential role of anti-LPS NAbs in the pleural cavity that should be further explored.PMID:38591123 | DOI:10.1152/ajplung.00377.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Ioannis Sarrigeorgiou Erasmia Rouka Ourania S Kotsiou Garyfallia Perlepe Efrosini S Gerovasileiou Konstantinos I Gourgoulianis Peggy Lymberi Sotirios G Zarogiannis Source Type: research
Chronic intermittent hypoxia elicits distinct transcriptomic responses among neurons and oligodendrocytes within the brainstem of mice
Am J Physiol Lung Cell Mol Physiol. 2024 Apr 9. doi: 10.1152/ajplung.00320.2023. Online ahead of print.ABSTRACTChronic intermittent hypoxia (CIH) is a prevalent condition characterized by recurrent episodes of oxygen deprivation, linked to respiratory and neurological disorders. Prolonged CIH is known to have adverse effects, including endothelial dysfunction, chronic inflammation, oxidative stress, and impaired neuronal function. These factors can contribute to serious comorbidities, including metabolic disorders and cardiovascular diseases. To investigate the molecular impact of CIH, we examined male C57BL/6J mice expose...
Source: Am J Physiol Lung Ce... - April 9, 2024 Category: Respiratory Medicine Authors: Hemalatha Bhagavan Aguan D Wei Luiz M Oliveira Kimberly A Aldinger Jan-Marino Ramirez Source Type: research
Low global arginine bioavailability: a common phenomenon in pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol. 2024 Apr 1;326(4):L514-L515. doi: 10.1152/ajplung.00026.2024.NO ABSTRACTPMID:38587550 | DOI:10.1152/ajplung.00026.2024 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 8, 2024 Category: Respiratory Medicine Authors: Dunia Hatabah Teresa De Marco Dana P McGlothlin Mary Malloy Loretta Z Reyes Rawan Korman Gregory J Kato Claudia R Morris Source Type: research
Low global arginine bioavailability: a common phenomenon in pulmonary hypertension
Am J Physiol Lung Cell Mol Physiol. 2024 Apr 1;326(4):L514-L515. doi: 10.1152/ajplung.00026.2024.NO ABSTRACTPMID:38587550 | DOI:10.1152/ajplung.00026.2024 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 8, 2024 Category: Respiratory Medicine Authors: Dunia Hatabah Teresa De Marco Dana P McGlothlin Mary Malloy Loretta Z Reyes Rawan Korman Gregory J Kato Claudia R Morris Source Type: research
Endothelial Knockdown of the Tumor Suppressor, WWOX, Increases Inflammation in Ventilator-Induced Lung Injury
CONCLUSION: Loss of WWOX function in ECs is associated with a heightened inflammatory response during mechanical stretch that is associated with increased MAPK phosphorylation and appears to be dependent on upregulation of zyxin.PMID:38563965 | DOI:10.1152/ajplung.00277.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 2, 2024 Category: Respiratory Medicine Authors: Zhenguo Zeng Eltyeb Abdelwahid Weiguo Chen Christian Ascoli Trinh Pham Jeffrey R Jacobson Steven M Dudek Viswanathan Natarajan C Marcelo Aldaz Roberto F Machado Sunit Singla Source Type: research
Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs
CONCLUSIONS: MSC-sEVs improved respiratory system physiology and alveolar formation in mechanically ventilated preterm lambs. MSC-sEVs may be an effective and safe therapy for appropriate functional and structural development of the lung in preterm infants who require mechanical ventilation and are at-risk of developing BPD.PMID:38563994 | DOI:10.1152/ajplung.00349.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 2, 2024 Category: Respiratory Medicine Authors: Kurt H Albertine Andrew Rebentisch Elaine Dawson Jakob Van Boerum Emily Major Juraj Štipka Hannah Foreman David Headden Zo ë Vordos Emily Beck Zhengming Wang Haixia Yang Baifeng Yu Mar Janna Dahl Donald M Null Davide Bizzotto Chiara Veneroni Anna Lavizz Source Type: research
Endothelial Knockdown of the Tumor Suppressor, WWOX, Increases Inflammation in Ventilator-Induced Lung Injury
CONCLUSION: Loss of WWOX function in ECs is associated with a heightened inflammatory response during mechanical stretch that is associated with increased MAPK phosphorylation and appears to be dependent on upregulation of zyxin.PMID:38563965 | DOI:10.1152/ajplung.00277.2023 (Source: Am J Physiol Lung Ce...)
Source: Am J Physiol Lung Ce... - April 2, 2024 Category: Respiratory Medicine Authors: Zhenguo Zeng Eltyeb Abdelwahid Weiguo Chen Christian Ascoli Trinh Pham Jeffrey R Jacobson Steven M Dudek Viswanathan Natarajan C Marcelo Aldaz Roberto F Machado Sunit Singla Source Type: research
