Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis
In conclusion, the 2 different medications have the same efficacy and safety for treating cutaneous leishmaniasis. Pentavalent antimoniate intralesional infiltration treatment is safe, effective, and well tolerated with minimal side effects for Old-World cutaneous leishmaniasis.PMID:38682801 | DOI:10.2340/actadv.v104.35089 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - April 29, 2024 Category: Dermatology Authors: Michal Solomon Ayelet Ollech Felix Pavlotsky Aviv Barzilai Eli Schwartz Sharon Baum Nadav Astman Source Type: research

Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis
In conclusion, the 2 different medications have the same efficacy and safety for treating cutaneous leishmaniasis. Pentavalent antimoniate intralesional infiltration treatment is safe, effective, and well tolerated with minimal side effects for Old-World cutaneous leishmaniasis.PMID:38682801 | DOI:10.2340/actadv.v104.35089 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - April 29, 2024 Category: Dermatology Authors: Michal Solomon Ayelet Ollech Felix Pavlotsky Aviv Barzilai Eli Schwartz Sharon Baum Nadav Astman Source Type: research

Comparison of Intralesional Sodium Stibogluconate versus Intralesional Meglumine Antimoniate for the Treatment of Leishmania major Cutaneous Leishmaniasis
In conclusion, the 2 different medications have the same efficacy and safety for treating cutaneous leishmaniasis. Pentavalent antimoniate intralesional infiltration treatment is safe, effective, and well tolerated with minimal side effects for Old-World cutaneous leishmaniasis.PMID:38682801 | DOI:10.2340/actadv.v104.35089 (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - April 29, 2024 Category: Dermatology Authors: Michal Solomon Ayelet Ollech Felix Pavlotsky Aviv Barzilai Eli Schwartz Sharon Baum Nadav Astman Source Type: research

The Pediatric Autism Research Cohort (PARC) Study: protocol for a patient-oriented prospective study examining trajectories of functioning in children with autism
Introduction The developmentally variable nature of autism poses challenges in providing timely services tailored to a child’s needs. Despite a recent focus on longitudinal research, priority-setting initiatives with stakeholders highlighted the importance of studying a child’s day-to-day functioning and social determinants of health to inform clinical care. To address this, we are conducting a pragmatic multi-site, patient-oriented longitudinal investigation: the Pediatric Autism Research Cohort (PARC) Study. In young children (<7 years of age) newly diagnosed with autism, we will: (1) examine variability i...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Kata, A., McPhee, P. G., Chen, Y.-J., Zwaigenbaum, L., Singal, D., Roncadin, C., Bennett, T., Carter, M., Di Rezze, B., Drmic, I., Duku, E., Fournier, S., Frei, J., Gentles, S. J., Georgiades, K., Hanlon-Dearman, A., Hoult, L., Kelley, E., Koller, J., de Tags: Open access, Paediatrics Source Type: research

Biomarkers and clinical outcomes after tezepelumab cessation: extended follow-up from the 2-year DESTINATION study
Long-term tezepelumab treatment in the DESTINATION study (NCT03706079) resulted in reduced asthma exacerbations, reduced biomarker levels and improved lung function and symptom control in patients with severe, uncontrolled asthma. (Source: Annals of Allergy, Asthma and Immunology)
Source: Annals of Allergy, Asthma and Immunology - April 29, 2024 Category: Allergy & Immunology Authors: Christopher E. Brightling, Marco Caminati, Jean-Pierre Llanos, Scott Caveney, Ales Kotalik, Janet M. Griffiths, Anna Lundahl, Elliot Israel, Ian D. Pavord, Michael E. Wechsler, Celeste Porsbjerg, Jonathan Corren, Monika Go łąbek, Neil Martin, Sandhia Po Source Type: research

Occurrence of coliforms and biofilm-forming bacteria in raw, treated, and distributed water from two waterwork systems in Osun State, Southwestern Nigeria
This study assessed the bacteriological quality of raw, treated, and distributed water from Ede-Erinle and Opa reservoirs in Osun State, Nigeria. This was to determine the potability of water from these waterwork stations. Eighteen sampling points were established across the two reservoir networks for this study. Samples were collected bi-monthly for two annual cycles. Serial dilution and pour plate methods were employed for the enumeration of bacterial load. Total heterotrophic bacteria count (THBC) and total coliform bacteria count (TCBC) were enumerated on nutrient and MacConkey agar at 37 °C, respectively. Bacterial i...
Source: Journal of Water and Health - April 28, 2024 Category: Environmental Health Authors: Abayomi Tolulope Oyewale Babatunde Wumi Odetoyin Anthonia Olufunke Oluduro Israel Funso Adeniyi Source Type: research

Expert Opinion on Current Trends in the Use of Insulin in the Management of People with Type 2 Diabetes from the South-Eastern European Region and Israel
AbstractDespite the availability of various antihyperglycaemic therapies and comprehensive guidelines, glycaemic control in diabetes management has not improved significantly during the last decade in the real-world clinical setting. Treatment inertia arising from a complex interplay among patient-, clinician- and healthcare-system-related factors is the prime reason for this suboptimal glycaemic control. Also, the key factor leading to inadequate glycaemic levels remains limited communication between healthcare professionals (HCPs) and people with type 2 diabetes (PwT2D). Early insulin administration has several advantage...
Source: Diabetes Therapy - April 27, 2024 Category: Endocrinology Source Type: research

High Twist expression can be an early event in lip carcinogenesis
ConclusionsThe results suggest that the high immunoexpression of Twist is an early lip carcinogenesis event. However, it appears not to influence the progression of ED in AC. (Source: Oral Surgery)
Source: Oral Surgery - April 27, 2024 Category: ENT & OMF Authors: Israel Leal  Cavalcante, Caio César da Silva Barros, Hellen Bandeira de Pontes Santos, Amanda Katarinny Goes Gonzaga, Silvia Helena Barem Rabenhorst, Roberta Barroso Cavalcante, Éricka Janine Dantas da Silveira, Ana Miryam Costa de Medeiros Tags: ORIGINAL ARTICLE Source Type: research

Attitudes of nurses, paramedics, and medics towards security prisoners: a cross-sectional study
Security prisoners in Israel are those imprisoned due to offenses involving harming state security or from nationalistic motivations. On the one hand, they are accused of a serious criminal offense that harmed... (Source: Health and Justice)
Source: Health and Justice - April 27, 2024 Category: Criminology Authors: Liel Hadida, Oren Wacht, Ilana Livshiz Riven and Orli Grinstein-Cohen Tags: Research Article Source Type: research