A New Method for Estimating Glomerular Filtration Rate in Rhesus Macaques (Macaca mulatta)
In this study, we aimed to determine if the Schwartz formula as used in human pediatric medicine can estimate GFR in rhesus macaques. We hypothesized that iohexol-GFR would correlate with the Schwartz formula-estimated GFR (eGFR) in irradiated and non-irradiated rhesus macaques. Twelve rhesus macaques [age 5-14 years (mean 7 years); 5 females, 7 males] with a range of BUN levels were selected for comparison to 4 non-irradiated controls (2 females, 2 males). Irradiated animals were divided by BUN into 3 groups: BUN ≤20 mg/dL (n = 4), BUN >20-24 mg/dL (n = 4), and BUN ≥25 mg/dL (n = 4). Baseline serum chemistry and ur...
Source: Radiation Research - October 30, 2023 Category: Physics Authors: Allison M Tomasino John D Olson George W Schaaf Anderson O Cox Cristina M Furdui J Mark Cline Eric P Cohen Source Type: research
A New Method for Estimating Glomerular Filtration Rate in Rhesus Macaques (Macaca mulatta)
In this study, we aimed to determine if the Schwartz formula as used in human pediatric medicine can estimate GFR in rhesus macaques. We hypothesized that iohexol-GFR would correlate with the Schwartz formula-estimated GFR (eGFR) in irradiated and non-irradiated rhesus macaques. Twelve rhesus macaques [age 5-14 years (mean 7 years); 5 females, 7 males] with a range of BUN levels were selected for comparison to 4 non-irradiated controls (2 females, 2 males). Irradiated animals were divided by BUN into 3 groups: BUN ≤20 mg/dL (n = 4), BUN >20-24 mg/dL (n = 4), and BUN ≥25 mg/dL (n = 4). Baseline serum chemistry and ur...
Source: Radiation Research - October 30, 2023 Category: Physics Authors: Allison M Tomasino John D Olson George W Schaaf Anderson O Cox Cristina M Furdui J Mark Cline Eric P Cohen Source Type: research
A New Method for Estimating Glomerular Filtration Rate in Rhesus Macaques (Macaca mulatta)
In this study, we aimed to determine if the Schwartz formula as used in human pediatric medicine can estimate GFR in rhesus macaques. We hypothesized that iohexol-GFR would correlate with the Schwartz formula-estimated GFR (eGFR) in irradiated and non-irradiated rhesus macaques. Twelve rhesus macaques [age 5-14 years (mean 7 years); 5 females, 7 males] with a range of BUN levels were selected for comparison to 4 non-irradiated controls (2 females, 2 males). Irradiated animals were divided by BUN into 3 groups: BUN ≤20 mg/dL (n = 4), BUN >20-24 mg/dL (n = 4), and BUN ≥25 mg/dL (n = 4). Baseline serum chemistry and ur...
Source: Radiation Research - October 30, 2023 Category: Physics Authors: Allison M Tomasino John D Olson George W Schaaf Anderson O Cox Cristina M Furdui J Mark Cline Eric P Cohen Source Type: research
A New Method for Estimating Glomerular Filtration Rate in Rhesus Macaques (Macaca mulatta)
In this study, we aimed to determine if the Schwartz formula as used in human pediatric medicine can estimate GFR in rhesus macaques. We hypothesized that iohexol-GFR would correlate with the Schwartz formula-estimated GFR (eGFR) in irradiated and non-irradiated rhesus macaques. Twelve rhesus macaques [age 5-14 years (mean 7 years); 5 females, 7 males] with a range of BUN levels were selected for comparison to 4 non-irradiated controls (2 females, 2 males). Irradiated animals were divided by BUN into 3 groups: BUN ≤20 mg/dL (n = 4), BUN >20-24 mg/dL (n = 4), and BUN ≥25 mg/dL (n = 4). Baseline serum chemistry and ur...
Source: Radiation Research - October 30, 2023 Category: Physics Authors: Allison M Tomasino John D Olson George W Schaaf Anderson O Cox Cristina M Furdui J Mark Cline Eric P Cohen Source Type: research
A New Method for Estimating Glomerular Filtration Rate in Rhesus Macaques (Macaca mulatta)
In this study, we aimed to determine if the Schwartz formula as used in human pediatric medicine can estimate GFR in rhesus macaques. We hypothesized that iohexol-GFR would correlate with the Schwartz formula-estimated GFR (eGFR) in irradiated and non-irradiated rhesus macaques. Twelve rhesus macaques [age 5-14 years (mean 7 years); 5 females, 7 males] with a range of BUN levels were selected for comparison to 4 non-irradiated controls (2 females, 2 males). Irradiated animals were divided by BUN into 3 groups: BUN ≤20 mg/dL (n = 4), BUN >20-24 mg/dL (n = 4), and BUN ≥25 mg/dL (n = 4). Baseline serum chemistry and ur...
Source: Radiation Research - October 30, 2023 Category: Physics Authors: Allison M Tomasino John D Olson George W Schaaf Anderson O Cox Cristina M Furdui J Mark Cline Eric P Cohen Source Type: research
Contrast media extravasation injury: a prospective observational cohort study
ConclusionRisk factors for moderate contrast media extravasation injury are malignant tumors, iohexol, large-volume (> 50 mL) extravasation, and back-of-the-hand injection. Analysis of these risk factors can help reduce the degree of injury after extravasation.Clinical relevance statementHigh-risk patients with extravasation support should choose the appropriate contrast media type, avoiding back-of-the-hand injections. We recommend that patients with cancer be implanted with a high-pressure resistant central venous catheter and receive effective measures to timely detect and reduce extravasation. (Source: European ...
Source: European Journal of Medical Research - October 25, 2023 Category: Research Source Type: research
Associations of Biomarkers of Tubular Injury and Inflammation with Biopsy Features in Type 1 Diabetes
CONCLUSIONS: Biomarkers of tubular injury and inflammation were associated with kidney structural parameters early type 1 diabetes and may be indicators of kidney disease risk.PMID:37871959 | DOI:10.2215/CJN.0000000000000333 (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - October 23, 2023 Category: Urology & Nephrology Authors: Christine P Limonte David K Prince Andrew N Hoofnagle Andrzej Galecki Irl B Hirsch Frances Tian Sushrut S Waikar Helen C Looker Robert G Nelson Alessandro Doria Michael Mauer Bryan R Kestenbaum Ian H de Boer Source Type: research
Stroke in a patient of anaphylaxis —a case report and brief review
ConclusionAn ischemic stroke in the setting of an anaphylaxis is a rare occurrence, which can be attributed to multiple factors in our patient. (Source: International Journal of Emergency Medicine)
Source: International Journal of Emergency Medicine - October 17, 2023 Category: Emergency Medicine Source Type: research
Contrast media-induced nephropathy in Tunisia: prospective case-control study with cardio-nephrological monitoring
CONCLUSION: the most effective approach for CMIN is prevention, which focuses on addressing modifiable risk factors to minimize the risk especially in patients with pre-existing renal failure.PMID:37808435 | PMC:PMC10559155 | DOI:10.11604/pamj.2023.45.144.30749 (Source: Molecular Medicine)
Source: Molecular Medicine - October 9, 2023 Category: Molecular Biology Authors: Meriam Hajji Hela Jebali Emna Chaabouni Khadija Mzoughi Ihssen Zairi Sondos Kraiem Lamia Raies Fethi Ben Hamida Lilia Ben Fatma Mohammed Karim Zouaghi Taieb Ben Abdallah Source Type: research
Contrast media-induced nephropathy in Tunisia: prospective case-control study with cardio-nephrological monitoring
CONCLUSION: the most effective approach for CMIN is prevention, which focuses on addressing modifiable risk factors to minimize the risk especially in patients with pre-existing renal failure.PMID:37808435 | PMC:PMC10559155 | DOI:10.11604/pamj.2023.45.144.30749 (Source: Molecular Medicine)
Source: Molecular Medicine - October 9, 2023 Category: Molecular Biology Authors: Meriam Hajji Hela Jebali Emna Chaabouni Khadija Mzoughi Ihssen Zairi Sondos Kraiem Lamia Raies Fethi Ben Hamida Lilia Ben Fatma Mohammed Karim Zouaghi Taieb Ben Abdallah Source Type: research
Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - October 5, 2023 Category: Physiology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research
Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - October 5, 2023 Category: Urology & Nephrology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research
Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - October 5, 2023 Category: Physiology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research
Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - October 5, 2023 Category: Urology & Nephrology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research
Salt-sensitive trait of normotensive individualsis associated with altered autonomous cardiac regulation: a randomized controlled intervention study
CONCLUSIONS: Salt sensitivity in normotensive individuals is not driven by extracellular fluid expansion. Yet, it is associated with an inability to decrease SVR upon high salt intake that is accompanied by alterations in autonomous cardiac regulation, as reflected by decreased cross-correlation baroreceptor sensitivity and heart rate variability.PMID:37795535 | DOI:10.1152/ajprenal.00076.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - October 5, 2023 Category: Physiology Authors: Jetta J Oppelaar Thomas A Bouwmeester Anastasia A Silova Didier Collard Rosa D Wouda Robert E van Duin Nienke M G Rorije Rik H G Olde Engberink A H Jan Danser Bert-Jan H van den Born Liffert Vogt Source Type: research
