Repeat bidirectional double-balloon enteroscopy 1 year later may be proper in Peutz-Jeghers patients with difficult-to-reach polyps
Conclusions The difficult-to-reach polyps may have a low risk of immediate symptomatic intussusception, possibly due to limited bowel mobility by extraluminal adhesions, and the likelihood of reaching them at repeat DBE was substantial. Hence, repeat DBE 1 year later may be proper in such patients with PJS. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Endoscopy International Open)
Source: Endoscopy International Open - December 12, 2023 Category: Gastroenterology Authors: Funayama, Yohei Oguro, Kunihiko Sakamoto, Hirotsugu Yano, Tomonori Owada, Jun Kobayashi, Takuma Ono, Yusuke Lefor, Alan Kawarai Yamamoto, Hironori Tags: Original article Source Type: research

Serum tRNA-derived fragments as potential biomarkers in children with acute intussusception
CONCLUSIONS: Circulating tRF-Leu-TAA-006, tRF-Gln-TTG-033 and tRF-Lys-TTT-028 expression might be a novel potential biomarker for diagnosis of pediatric intussusception.PMID:38058713 | PMC:PMC10696982 | DOI:10.5114/aoms/140491 (Source: Archives of Medical Science)
Source: Archives of Medical Science - December 7, 2023 Category: Biomedical Science Authors: Lian Zhao Wei Chen Wan-Liang Guo Source Type: research

Management of a Rare Challenging Case of Duodenal Ampullary Lipoma
AbstractDuodenal lipoma is a very rare entity with limited case reports present in literature. But duodenal ampullary lipomas are even more rare in nature. Owing to the recent advances in endoscopy and modern imaging techniques, more cases are being diagnosed and treated. However, challenge lies in performing a less invasive and least morbid procedures to treat them surgically in such complex location of tumour. To study the diagnosis and treatment of duodenal ampullary lipoma in a young male patient and challenges faced during surgical management. A 15-year-old young boy presented to us with complaints of intermittent upp...
Source: Indian Journal of Surgical Oncology - December 7, 2023 Category: Cancer & Oncology Source Type: research

A real-world analysis of safety profile of selexipag by using FDA adverse event Reporting System (FAERS)
CONCLUSIONS: The findings contribute valuable insights to clinical practice, reinforcing the importance of vigilant monitoring, and can be instrumental in guiding both therapeutic applications and safety assessments of this particular medication.PMID:38032065 | DOI:10.1080/14740338.2023.2290633 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - November 30, 2023 Category: Drugs & Pharmacology Authors: Jie Zhao Mei Wang Qing Yu Yi Yang Bin Zhang Sanhua Zhan Source Type: research

Point of Care Ultrasound in Pediatric Surgery across the European Region —European Pediatric Surgery Association Endorsed Survey
Conclusion There is a wide spectrum of POCUS use in pediatric surgery across Europe. For those surgeons who practice POCUS, it is most used for the diagnosis of abdominal conditions. There are differing views among clinicians concerning the most useful applications of POCUS. The extent to which ultrasound is taught during pediatric surgery training differs substantially across European curricula. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - November 28, 2023 Category: Surgery Authors: Lindert, Judith Rolle, Udo Naidoo, Gerlin Tags: Original Article Source Type: research

Intussusception reduction methods in daily practice —a survey by the European Society of Paediatric Radiology Abdominal Imaging Taskforce
ConclusionThere is wide variation in how image-guided intussusception reduction is performed, and in the use of sedation/anaesthesia. (Source: Pediatric Radiology)
Source: Pediatric Radiology - November 22, 2023 Category: Radiology Source Type: research

Long time consequences after STARR procedure: Report of 15 years experience and medico-legal perspective
Stapled transanal rectal resection is the most surgical procedure used for obstructed defecation syndrome, rectal prolapse, rectocele and rectal intussusception worldwide.The aim of this study is to report our experience and long time consequences and to offer a new medico-legal perspective. (Source: American Journal of Surgery)
Source: American Journal of Surgery - November 21, 2023 Category: Surgery Authors: Remo Andreoli, Nicola Zampieri, Simone Orlandi, Andrea Geccherle, Roberto L. Castellani Tags: Original Research Article Source Type: research

Therapeutic targeting of angiopoietins in tumor angiogenesis and cancer development
Biochem Biophys Res Commun. 2023 Oct 21;687:149130. doi: 10.1016/j.bbrc.2023.149130. Online ahead of print.ABSTRACTThe formation and progression of tumors in humans are linked to the abnormal development of new blood vessels known as neo-angiogenesis. Angiogenesis is a broad word that encompasses endothelial cell migration, proliferation, tube formation, and intussusception, as well as peri-EC recruitment and extracellular matrix formation. Tumor angiogenesis is regulated by angiogenic factors, out of which some of the most potent angiogenic factors such as vascular endothelial growth factor and Angiopoietins (ANGs) in the...
Source: Cell Research - November 9, 2023 Category: Cytology Authors: Komal Thapa Heena Khan Gagandeep Kaur Puneet Kumar Thakur Gurjeet Singh Source Type: research

Therapeutic targeting of angiopoietins in tumor angiogenesis and cancer development
Biochem Biophys Res Commun. 2023 Oct 21;687:149130. doi: 10.1016/j.bbrc.2023.149130. Online ahead of print.ABSTRACTThe formation and progression of tumors in humans are linked to the abnormal development of new blood vessels known as neo-angiogenesis. Angiogenesis is a broad word that encompasses endothelial cell migration, proliferation, tube formation, and intussusception, as well as peri-EC recruitment and extracellular matrix formation. Tumor angiogenesis is regulated by angiogenic factors, out of which some of the most potent angiogenic factors such as vascular endothelial growth factor and Angiopoietins (ANGs) in the...
Source: Biochemical and Biophysical Research communications - November 9, 2023 Category: Biochemistry Authors: Komal Thapa Heena Khan Gagandeep Kaur Puneet Kumar Thakur Gurjeet Singh Source Type: research

Therapeutic targeting of angiopoietins in tumor angiogenesis and cancer development
Biochem Biophys Res Commun. 2023 Oct 21;687:149130. doi: 10.1016/j.bbrc.2023.149130. Online ahead of print.ABSTRACTThe formation and progression of tumors in humans are linked to the abnormal development of new blood vessels known as neo-angiogenesis. Angiogenesis is a broad word that encompasses endothelial cell migration, proliferation, tube formation, and intussusception, as well as peri-EC recruitment and extracellular matrix formation. Tumor angiogenesis is regulated by angiogenic factors, out of which some of the most potent angiogenic factors such as vascular endothelial growth factor and Angiopoietins (ANGs) in the...
Source: Biochemical and Biophysical Research communications - November 9, 2023 Category: Biochemistry Authors: Komal Thapa Heena Khan Gagandeep Kaur Puneet Kumar Thakur Gurjeet Singh Source Type: research

Unusual presentation of ileal intussusception due to submucosal lipoma in a child and its management
Nisha Girish, Naveen Thomas, Gayathri Natraj, KV Satish Kumar, Neena JohnJournal of Indian Association of Pediatric Surgeons 2023 28(6):517-519 Idiopathic intussusception is the most common form of intussusception in infants and young children. In older children and adults, intussusception being rare, the lead point is usually an underlying bowel pathology (Meckel's diverticulum, hemangioma, carcinoids, polyps, submucous lipomas, etc.) and these are called pathological lead points (PLP's). The management of an obese child with recurrent abdominal pain for over 2 years, diagnosed with ileo-ileal intus...
Source: Journal of Indian Association of Pediatric Surgeons - November 2, 2023 Category: Surgery Authors: Nisha Girish Naveen Thomas Gayathri Natraj KV Satish Kumar Neena John Source Type: research