Patterns of recurrence in HNSCC patients treated definitively with upfront surgery, chemoradiation
CONCLUSION: Locoregional control and RFS benefit was observed in surgically treated p16 negative LA-OPSCC patients. Locoregional recurrence is the main reason of treatment failure in LA-HNSCC, occurring commonly within the first 2 years post-treatment, regardless of treatment option.PMID:38498191 | DOI:10.1007/s00405-024-08556-6 (Source: Cancer Control)
Source: Cancer Control - March 18, 2024 Category: Cancer & Oncology Authors: Pei Yuan Fong Thomas Kwok Seng Loh Liang Shen Donovan Kum Chuen Eu Chwee Ming Lim Source Type: research

Cancers, Vol. 16, Pages 1180: PIP4K2B Protein Regulation by NSD1 in HPV-Negative Head and Neck Squamous Cell Carcinoma
In conclusion, our findings implicate PIP4K2B as a novel NSD1-dependent protein in HNSCC, suggesting its potential significance for laryngeal cancer cell survival. This insight contributes to our understanding of the molecular landscape in HNSCC and establishes PIP4KB as a promising target for drug development. (Source: Cancers)
Source: Cancers - March 17, 2024 Category: Cancer & Oncology Authors: Iuliia Topchu Igor Bychkov Ekaterina Roshchina Petr Makhov Yanis Boumber Tags: Article Source Type: research

Factors associated with oral hygiene compliance in patients treated with radiation therapy for head and neck cancer
CONCLUSIONS: The reasons for the cohort of patients with HNC in this study being OHNC are multifaceted and relate to socioeconomic factors and cancer characteristics.PRACTICAL IMPLICATIONS: Finding ways to increase OHC and fluoride use among patients with HNC who are at greatest risk of being OHNC should be explored.PMID:38456849 | DOI:10.1016/j.adaj.2023.11.018 (Source: Journal of the American Dental Association)
Source: Journal of the American Dental Association - March 8, 2024 Category: Dentistry Authors: Jiwon Lim Erika S Helgeson Rajesh V Lalla Thomas P Sollecito Nathaniel S Treister Brian L Schmidt Lauren L Patton Alexander Lin Zvonimir Milas Michael T Brennan Source Type: research

Supraclavicular artery island flap for treatment of cervical wound defects and persistent cerebrospinal fluid leaks: A technical note and systematic review of the literature
CONCLUSION: The SAI flap technique provided wound defect coverage in this case and is suitable for addressing issues such as persistent CSF leaks or soft tissue coverage after cervical spine surgery.PMID:38458254 | DOI:10.1016/j.wneu.2024.02.151 (Source: Cancer Control)
Source: Cancer Control - March 8, 2024 Category: Cancer & Oncology Authors: Esteban Quiceno Mohamed Ar Soliman Asham Khan Maria Jose Cavagnaro Ryan P McSpadden John Pollina Elad I Levy Jeffrey P Mullin Source Type: research

Factors associated with oral hygiene compliance in patients treated with radiation therapy for head and neck cancer
CONCLUSIONS: The reasons for the cohort of patients with HNC in this study being OHNC are multifaceted and relate to socioeconomic factors and cancer characteristics.PRACTICAL IMPLICATIONS: Finding ways to increase OHC and fluoride use among patients with HNC who are at greatest risk of being OHNC should be explored.PMID:38456849 | DOI:10.1016/j.adaj.2023.11.018 (Source: Journal of the American Dental Association)
Source: Journal of the American Dental Association - March 8, 2024 Category: Dentistry Authors: Jiwon Lim Erika S Helgeson Rajesh V Lalla Thomas P Sollecito Nathaniel S Treister Brian L Schmidt Lauren L Patton Alexander Lin Zvonimir Milas Michael T Brennan Source Type: research