A comparison of endoscopic endonasal versus open approaches for skull base chordoma: a comprehensive National Cancer Database analysis
CONCLUSIONS: The endoscopic endonasal approach has been increasingly utilized over time and touts noninferiority with respect to safety and efficacy with a marked improvement in LOS, which carries substantial implications for both healthcare costs and enhanced patient recovery. Future prospective studies are necessary to further delineate trends and surgical outcomes for skull base chordoma.PMID:38691856 | DOI:10.3171/2024.2.FOCUS23933 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Justin M Soffer Ruben Ulloa Sonja Chen Ryan S Ziltzer Vijay A Patel Sean P Polster Source Type: research

A comparison of endoscopic endonasal versus open approaches for skull base chordoma: a comprehensive National Cancer Database analysis
CONCLUSIONS: The endoscopic endonasal approach has been increasingly utilized over time and touts noninferiority with respect to safety and efficacy with a marked improvement in LOS, which carries substantial implications for both healthcare costs and enhanced patient recovery. Future prospective studies are necessary to further delineate trends and surgical outcomes for skull base chordoma.PMID:38691856 | DOI:10.3171/2024.2.FOCUS23933 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Justin M Soffer Ruben Ulloa Sonja Chen Ryan S Ziltzer Vijay A Patel Sean P Polster Source Type: research

A comparison of endoscopic endonasal versus open approaches for skull base chordoma: a comprehensive National Cancer Database analysis
CONCLUSIONS: The endoscopic endonasal approach has been increasingly utilized over time and touts noninferiority with respect to safety and efficacy with a marked improvement in LOS, which carries substantial implications for both healthcare costs and enhanced patient recovery. Future prospective studies are necessary to further delineate trends and surgical outcomes for skull base chordoma.PMID:38691856 | DOI:10.3171/2024.2.FOCUS23933 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Justin M Soffer Ruben Ulloa Sonja Chen Ryan S Ziltzer Vijay A Patel Sean P Polster Source Type: research

A comparison of endoscopic endonasal versus open approaches for skull base chordoma: a comprehensive National Cancer Database analysis
CONCLUSIONS: The endoscopic endonasal approach has been increasingly utilized over time and touts noninferiority with respect to safety and efficacy with a marked improvement in LOS, which carries substantial implications for both healthcare costs and enhanced patient recovery. Future prospective studies are necessary to further delineate trends and surgical outcomes for skull base chordoma.PMID:38691856 | DOI:10.3171/2024.2.FOCUS23933 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Justin M Soffer Ruben Ulloa Sonja Chen Ryan S Ziltzer Vijay A Patel Sean P Polster Source Type: research

A comparison of endoscopic endonasal versus open approaches for skull base chordoma: a comprehensive National Cancer Database analysis
CONCLUSIONS: The endoscopic endonasal approach has been increasingly utilized over time and touts noninferiority with respect to safety and efficacy with a marked improvement in LOS, which carries substantial implications for both healthcare costs and enhanced patient recovery. Future prospective studies are necessary to further delineate trends and surgical outcomes for skull base chordoma.PMID:38691856 | DOI:10.3171/2024.2.FOCUS23933 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - May 1, 2024 Category: Neurosurgery Authors: Justin M Soffer Ruben Ulloa Sonja Chen Ryan S Ziltzer Vijay A Patel Sean P Polster Source Type: research

A machine learning model for the early diagnosis of bloodstream infection in patients admitted to the pediatric intensive care unit
by Felipe Liporaci, Danilo Carlotti, Ana Carlotti Bloodstream infection (BSI) is associated with increased morbidity and mortality in the pediatric intensive care unit (PICU) and high healthcare costs. Early detection and appropriate treatment of BSI may improve patient’s outcome. Data on machine-learning models to predict BSI in pediatric pati ents are limited and neither study included time series data. We aimed to develop a machine learning model to predict an early diagnosis of BSI in patients admitted to the PICU. This was a retrospective cohort study of patients who had at least one positive blood culture result d...
Source: PLoS One - May 1, 2024 Category: Biomedical Science Authors: Felipe Liporaci Source Type: research

Mp-483494-002 eliminating steam pops and improving lesion safety in atrial ablation with conductive hydrogels
Atrial fibrillation (AF) affects millions worldwide, leading to significant healthcare costs, stroke, and heart failure. The most common treatment option, radiofrequency (RF) ablation, has limitations including poor contact and suboptimal thermal coupling. (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2024 Category: Cardiology Authors: Lukas M. Jaworski, Drew Bernard, Allison Post, Elizabeth Cosgriff-Hernandez, Mehdi Razavi Source Type: research

Real-world total cost of care by line of therapy in relapsed/refractory diffuse large B-Cell lymphoma
Conclusion: Total healthcare costs increased with each additional LoT in the R/R DLBCL setting. Further improvements of first-line treatments that reduce the need for subsequent LoTs would potentially lessen the economic burden of DLBCL.PMID:38686393 | DOI:10.1080/13696998.2024.2349472 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 30, 2024 Category: Health Management Authors: Justin Gatwood Anthony Masaquel David Fox Daniel Sheinson Cameron James Jia Li Farah Hossain Ryan Ross Source Type: research

Real-world total cost of care by line of therapy in relapsed/refractory diffuse large B-cell lymphoma
CONCLUSION: Total healthcare costs increased with each additional LoT in the R/R DLBCL setting. Further improvements of first-line treatments that reduce the need for subsequent LoTs would potentially lessen the economic burden of DLBCL.PMID:38686393 | DOI:10.1080/13696998.2024.2349472 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 30, 2024 Category: Health Management Authors: Justin Gatwood Anthony Masaquel David Fox Daniel Sheinson Cameron James Jia Li Farah Hossain Ryan Ross Source Type: research

Gastric Alimetry ® Testing and Healthcare Economic Analysis in Nausea and Vomiting Syndromes
ConclusionsHealthcare utilisation and confirmatory testing rates remain high in nausea and vomiting syndromes. This study presents real-world data, together with a decision-tree analysis, showing Gastric Alimetry can streamline clinical care pathways, resulting in reduced healthcare utilisation and cost. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 30, 2024 Category: Gastroenterology Source Type: research