Cardiovascular diseases in Switzerland - Prevalence and care
Praxis (Bern 1994). 2024 Mar;113(3):57-66.ABSTRACTCardiovascular diseases (CVD) represent a significant health problem worldwide and in Switzerland. Despite preventive measures and advances in treatment, cardiovascular diseases still lead to a significant number of hospitalizations in Switzerland (133 000 in 2021) and are for responsible for almost 1/3 of all deaths (19 600 in 2021). Emergency care for acute cardiovascular events now has a very high standard in Switzerland compared to other countries. However, there is a large discrepancy between evidence and daily practice (evidence-performance gap) in cardiovascular risk...
Source: Praxis - April 24, 2024 Category: General Medicine Authors: Thomas Rosemann Agn ès Bachofner Oliver Strehle Source Type: research

Economic analysis of surgical outcome monitoring using control charts: the SHEWHART cluster randomised trial
Conclusions Using control charts paired with indicator feedback to surgical teams was associated with significant reductions in hospital bed-days within 30 days following surgery, and hospital costs reimbursed for this care by the insurer. Trial registration number NCT02569450. (Source: BMJ Quality and Safety)
Source: BMJ Quality and Safety - April 24, 2024 Category: General Medicine Authors: Skinner, S., Pascal, L., Polazzi, S., Chollet, F., Lifante, J.-C., Duclos, A., On behalf of the SHEWHART Trial Group Tags: Open access, Editor's choice Original research Source Type: research

Quality of life in Prolactinoma: A systematic review
ConclusionPoor quality of life in prolactinoma is multifactorial, related to biochemical control, side effects of therapy, and sellar mass effect. Targeting persistent symptoms, reducing healthcare costs, and reducing side-effects of therapy are avenues to improving QOL in patients with prolactinoma. (Source: Pituitary)
Source: Pituitary - April 24, 2024 Category: Endocrinology Source Type: research

Cost of disease progression among US patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
Conclusion: Disease progression was associated with significant increases in HCRU and costs. Delays in progression were associated with lower cumulative healthcare costs. Earlier use of more clinically effective treatments to delay progression may reduce the economic burden among these patients.PMID:38647165 | DOI:10.57264/cer-2023-0166 (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - April 22, 2024 Category: General Medicine Authors: Clara Lam Brandon Diessner Katherine Andrade Sydnie Stackland Leah Park Sandhya Mehta Feng Lin Winghan Jackie Kwong Source Type: research

Impact of < em > pseudomonas aeruginosa < /em > on resource utilization and costs in patients with exacerbated non-cystic fibrosis bronchiectasis
Conclusion Exacerbated NCFB with PA+ was associated with increased antibiotic usage, greater resource utilization, and increased costs. The major contributor to the cost differences was the use of inpatient services. Treatment strategies aimed at reducing the need for inpatient treatment could lessen the disparities observed in patients with NCFB.PMID:38646702 | DOI:10.1080/13696998.2024.2340382 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 22, 2024 Category: Health Management Authors: Meg Franklin Michael E Minshall Federica Pontenani Sunjay Devarajan Source Type: research

Cost of disease progression among US patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
Conclusion: Disease progression was associated with significant increases in HCRU and costs. Delays in progression were associated with lower cumulative healthcare costs. Earlier use of more clinically effective treatments to delay progression may reduce the economic burden among these patients.PMID:38647165 | PMC:PMC11036880 | DOI:10.57264/cer-2023-0166 (Source: Journal of Comparative Effectiveness Research)
Source: Journal of Comparative Effectiveness Research - April 22, 2024 Category: General Medicine Authors: Clara Lam Brandon Diessner Katherine Andrade Sydnie Stackland Leah Park Sandhya Mehta Feng Lin Winghan Jackie Kwong Source Type: research

Advancing pain management for extremity trauma: the evolution of ultrasound-guided nerve blocks for patients in the supine position in trauma centers
ConclusionUltrasound-guided nerve blocks present a promising avenue for early pain management in extremity trauma patients positioned supinely. Their implementation can lead to improved patient outcomes by alleviating pain severity, reducing opioid consumption, and cutting down healthcare costs. Further research and clinical integration of these techniques is imperative to enhance pain management protocols in trauma centers. (Source: European Journal of Trauma and Emergency Surgery)
Source: European Journal of Trauma and Emergency Surgery - April 22, 2024 Category: Emergency Medicine Source Type: research

Surveillance and prevention of healthcare-associated infections: best practices to prevent ventilator-associated events
Expert Rev Anti Infect Ther. 2024 Apr 22:1-16. doi: 10.1080/14787210.2024.2345877. Online ahead of print.ABSTRACTINTRODUCTION: Ventilator associated pneumonia (VAP) leads to an increase in morbidity, mortality, and healthcare costs. In addition to increased evidence from the latest European and American guidelines (published in 2017 and 2022, respectively), in the last two years, several important clinical experiences have added new prevention tools to be included to improve the management of VAP.AREAS COVERED: This paper is a narrative review of new evidence on VAP prevention. We divided VAP prevention measures into pharm...
Source: Expert Review of Anti-Infective Therapy - April 20, 2024 Category: Infectious Diseases Authors: Leonardo Lorente Joan Sabater-Riera Jordi Rello Source Type: research