Dracunculiasis (Guinea Worm Disease GWD) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Attribute-centred theorizing to address behavioural changes
We describe a framework for operationalizing attribute-centred theorizing, which includes generating behavioural attributes, verifying and testing those attributes, and constructing a behavioural matrix to inform campaigns or interventions. We illustrate this framework using the examples of Guinea-worm disease and cardiovascular diseases. The benefits of our approach include the ability to inform intervention development and the ability to generalize across different behaviours; however, more research on converting the behavioural matrix into actual policy is needed.PMID:34737475 | PMC:PMC8542264 | DOI:10.2471/BLT.20.28536...
Source: Bulletin of the World Health Organization - November 5, 2021 Category: International Medicine & Public Health Authors: Rajiv N Rimal Maria Knight Lapinski Source Type: research

Progress Toward Global Eradication of Dracunculiasis, January 2020-June 2021
This report describes progress during January 2020-June 2021 and updates previous reports (2,4,5).PMID:34735420 | DOI:10.15585/mmwr.mm7044a1 (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - November 4, 2021 Category: Epidemiology Authors: Donald R Hopkins Adam J Weiss Sharon L Roy Sarah Yerian Vitaliano A Cama Source Type: research

Assessment of the Chad guinea worm surveillance information system: A pivotal foundation for eradication
ConclusionsBased on these findings, we proposed a four-phased roadmap for centralizing data systems and transitioning to an electronic data capture system. These included: development of a data governance plan, transition to electronic data entry and centralized data storage, transition to a relational database, and cloud-based integration. The method and outcome of this assessment could be used by other neglected tropical disease programs looking to transition to modern electronic data capture systems. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - August 9, 2021 Category: Tropical Medicine Authors: Saugat Karki Source Type: research

Quantifying conflict zones as a challenge to certification of Guinea worm eradication in Africa: a new analytical approach
Conclusions Understanding the spatial–temporal patterns of conflict events, identifying hotspots, the actors responsible and their sphere of influence is critical for the GWEP and other public health programmes to develop practical risk assessments, deliver essential health interventions, implement innovative surveillance, determine certification and meet the goals of eradication. (Source: BMJ Open)
Source: BMJ Open - August 5, 2021 Category: General Medicine Authors: Kelly-Hope, L. A., Molyneux, D. H. Tags: Open access, Global health Source Type: research

Alternative transmission pathways for guinea worm in dogs: implications for outbreak risk and control
Int J Parasitol. 2021 Jul 8:S0020-7519(21)00213-7. doi: 10.1016/j.ijpara.2021.05.005. Online ahead of print.ABSTRACTGuinea worm (Dracunculus medinensis) has exerted a high human health burden in parts of Africa. Complete eradication of Guinea worm disease (dracunculiasis) may be delayed by the circulation of the parasite in domestic dogs. As with humans, dogs acquire the parasite by directly ingesting infected copepods, and recent evidence suggests that consuming frogs that ingested infected copepods as tadpoles may be a viable transmission route (paratenic route). To understand the relative contributions of direct and par...
Source: International Journal for Parasitology - July 11, 2021 Category: Parasitology Authors: John E Vinson Andrew W Park Christopher A Cleveland Michael J Yabsley Vanessa O Ezenwa Richard J Hall Source Type: research

Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Korean J Parasitol. 2021 Jun;59(3):189-225. doi: 10.3347/kjp.2021.59.3.189. Epub 2021 Jun 21.ABSTRACTThe use of albendazole and mebendazole, i.e., benzimidazole broad-spectrum anthelmintics, in treatment of parasitic infections, as well as cancers, is briefly reviewed. These drugs are known to block the microtubule systems of parasites and mammalian cells leading to inhibition of glucose uptake and transport and finally cell death. Eventually they exhibit ovicidal, larvicidal, and vermicidal effects on parasites, and tumoricidal effects on hosts. Albendazole and mebendazole are most frequently prescribed for treatment of i...
Source: Korean Journal of Parasitology - July 4, 2021 Category: Parasitology Authors: Jong-Yil Chai Bong-Kwang Jung Sung-Jong Hong Source Type: research