How can Warfarin be safe “ even in ” first trimester of pregnancy ? The story behind the 5 mg cut-off !
The well known pro-coagulant state of pregnancy is an evolutionary protective process to make blood clot quicker, to save fetal loss in early pregnancy and mitigate postpartum bleeding. Still, in many women, this natural adaptive process confers an enhanced thrombotic risk. The molecular mechanisms for this pro-coagulant state are, there is increased factor VII, fibrinogen, reduced protein S. It is interesting to note, while plasminogen levels are elevated, D-dimer is also increased, indicating an ongoing fight between pro & anticoagulant forces, converting the physiological maternal- placental bed a mini harmless DIC ...
Source: Dr.S.Venkatesan MD - March 20, 2024 Category: Cardiology Authors: dr s venkatesan Tags: cardiology -pregnancy Pregnancy and heart pregnancy and heart disease Uncategorized carpreg registry zahara esc acc guidelines on pregnancy and heart disease first trmestr use of oac warfarin heparin switch over lmwh bridge in pregnancy Source Type: blogs
What ’ s a skeuomorph, anyway?
A skeuomorph, derived from the Greek skeuos, meaning container or tool, and morphe, meaning shape, refers to a design element retaining attributes of older structures that are redundant in the current form. These elements serve to imbue novelty with familiarity, aiding users in understanding new devices or systems.
They’re not solely functional; aesthetic considerations often prompt their use. There are lots of examples: pottery adorned with imitation rivets reminiscent of metal pots, lightbulbs mimicking candle flames complete with a flickering effect, and software calendars and address books resembling their paper ...
Source: David Bradley Sciencebase - Songs, Snaps, Science - March 1, 2024 Category: Science Authors: David Bradley Tags: Technology Source Type: blogs
What Health IT Trend Has You Most Excited?
Burnout is something that can slowly creep up on you but take a long time to crawl out of. This serious problem is something that happens with you are overworked and overstressed from the problems you are tasked with at work. In the world of healthcare, where we are constantly looking for ways to make things better, it is no surprise that we are facing a high burnout rate. While burnout is hard to recover from, it is possible. Taking time off and finding things that you enjoy and are excited about are key to letting your brain reset and being ready to get back to work.
While there are countless problems and struggles in he...
Source: EMR and HIPAA - February 28, 2024 Category: Information Technology Authors: Grayson Miller Tags: AI/Machine Learning Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System 86Borders Arcadia Authenticx AVIA Health Blake Richards Dan McDonald Elucid Eric Prugh Health IT Trends Healthcare AI Source Type: blogs
Fight Aging! Newsletter, February 26th 2024
In conclusion, mTORC1 signaling contributes to the ISC fate decision, enabling regional control of intestinal cell differentiation in response to nutrition.
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Reviewing the Development of Senotherapeutics to Treat Aging
https://www.fightaging.org/archives/2024/02/reviewing-the-development-of-senotherapeutics-to-treat-aging/
Senescent cells accumulate with age and contribute meaningfully to chronic inflammation and degenerative aging. Destroying these cells produces rapid and sizable reversal of age-related diseases in mice, demonstrating that the presence of senescence cells ...
Source: Fight Aging! - February 25, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Whole Roasted Squash With Tomato-Ginger Chickpeas & Za ’atar
I read myself the riot act about 6 months ago, when my cholesterol level reached a new high. My doctor seemed nonplussed, perhaps because my cardiac calcium score was a perfect zero. But I was not happy. Yes, I had lost weight and was exercising, but to be honest, my heart belonged to cheese. And eggs. And ice cream. Something had to change.
Breakfast was easy. The whole eggs (which I had been eating almost daily) were replaced by Starbucks Sous Vide Egg whites or oatmeal served with a side of chicken sausage. Lunches were yogurt or soup or vegan bean burritos or salad or tuna or peanut butter. I started snacking on nu...
Source: The Blog That Ate Manhattan - February 21, 2024 Category: Primary Care Authors: Margaret Polaneczky, MD Tags: Vegetables Butternut Squash Chickpeas vegetarian za'atar Source Type: blogs
To What Degree is Alzheimer's Disease a Modern Phenomenon?
Here find an interesting commentary on what might be gleaned of the prevalence of Alzheimer's disease in antiquity from the body of ancient writings on the topic of aging, memory, and health. The consensus is that Alzheimer's disease is a creation of modernity, some combination of a longer life expectancy for a greater fraction of the population coupled with increased calorie intake and less active lives. Yet unlike type 2 diabetes, risk of Alzheimer's risk doesn't correlate well with the usual suspect lifestyle choices that raise the risk of age-related disease and lower life expectancy.
This line of thinking has l...
Source: Fight Aging! - February 19, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
What ’ s in a name?
What names we give the flora and fauna. Names are critical for scientific discourse and general conversation alike. They can be weird and wonderful, informative, confusing, hilarious even, and sometimes baffling. While common, or vernacular, names vary wildly, science, of course, has a relatively standardised method of naming living things. The common format, which is often colloquially known as the Latin name, is to have the species in a genus, a family group, and then to follow that genus name with the species name.
For example, in the UK, we might talk of the Snowdrop, or the Common Snowdrop. This delicate plant with wh...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 16, 2024 Category: Science Authors: David Bradley Tags: Biology Science Source Type: blogs
The Winter Moth – Operophtera brumata
This unassuming little moth has a suitably unassuming little name. It is known as the Winter Moth. It is one of the geometers, or what is referred to as inchworms in North America, because the larvae seem to measure out the earth as they move inch by inch.
The Winter Moth, Operophtera brumata, has internal antifreeze to help it survive the cold
The Winter Moth is not to be confused with the November nor the December Moth. It flies at the opposite end of the season to most other moths – October to December and sometimes into January and even February. It is unlikely to ever cross paths with the Spring Usher, the May o...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 9, 2023 Category: Science Authors: David Bradley Tags: Lepidoptera Source Type: blogs
Answer to Case 730
Answer tothe Parasite Case of the Week 730:Acanthamoebakeratitis.As noted by Anonymous, the pictures are a perfect rendition of the “thorny”Acanthamoeba trophozoite and its polygonal cyst (acanth is New Latin, from Greek akanthos, from akanthathorn, spine). Cysts have 2 layers: a wrinkled outer layer (ectocyst) and inner layer (endocyst) that can be polygonal, spherical, hexagonal, or star-shaped.Dr. Satishkumar Krishnam further described the trophozoite as " characterized by spine like pseudopodia (acanthopodia). " Chuck Blend noted that it looks like the first few seconds of a new proto-universe formi...
Source: Creepy Dreadful Wonderful Parasites - November 9, 2023 Category: Parasitology Source Type: blogs
Some Like It Hot! A Century-Old Disease on Our Southern Shores
By MIKE MAGEE
Naomi Orestes PhD, Professor of the History of Science at Harvard, didn’t mince words as she placed our predicament in context when she said, “If you know your Greek tragedies you know power, hubris, and tragedy go hand in hand. If we don’t address the harmful aspects of human activities, most obviously disruptive climate change, we are headed for tragedy.”
At the time, as a member of the Anthropocene Workgroup, she and a group of international climate scientists were focused on defining and measuring nine “planetary boundaries,” environmental indicators of planetary health. At...
Source: The Health Care Blog - October 30, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Avian Flu Climate Change Pandemic Sea level change Yellow Fever Source Type: blogs
“Doomscrolling” – Call the doctor!
by MIKE MAGEE
Exactly 1 year ago, mental health experts alerted the medical world to their version of an assessment scale for yet another new condition – “doomscrolling.”
As defined in the article, “Constant exposure to negative news on social media and news feeds could take the form of ‘doomscrolling’ which is commonly defined as a habit of scrolling through social media and news feeds where users obsessively seek for depressing and negative information.”
No one can deny a range of legitimate concerns. Faced with continued background noise from the pandemic, add global warming, renegade AI, and...
Source: The Health Care Blog - October 25, 2023 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice Democracy Doomscrolling Nurses Physicians Source Type: blogs
A Periodic Look at Elements
It’s National Chemistry Week! To celebrate, we’re looking back at a few recent blog posts highlighting elements important for human health and scientific research. Check out the posts and tell us what your favorite element is in the comments section!
Credit: Adapted from Compound Interest. CC BY-NC-ND 4.0.
Got Calcium?
Calcium is the most abundant mineral in our bodies. It’s essential for lots of important functions—including keeping bones strong and allowing muscles to move. Even clicking on this post to learn more about its many roles requires calcium!
Credit: Adapted from Compound...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - October 18, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Element Source Type: blogs
Out of Control Health Costs or a Broken Society
Flawed Accounting for the US Health Spending Problem
By Jeff Goldsmith
Source: OECD, Our World in Data
Late last year, I saw this chart which made my heart sink. It compared US life expectancy to its health spending since 1970 vs. other countries. As you can see, the US began peeling off from the rest of the civilized world in the mid-1980’s. Then US life expectancy began falling around 2015, even as health spending continued to rise. We lost two more full years of life expectancy to COVID. By the end of 2022, the US had given up 26 years-worth of progress in life expectancy gains. Adding four more ...
Source: The Health Care Blog - October 9, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy COVID Drug Overdoses gun violence Hospitals Jeff Goldsmith Maternal mortality Mental Health Obesity Poverty Regional Economy Society Source Type: blogs
Out of Control Health Costs or a Broken Society
Flawed Accounting for the US Health Spending Problem
By Jeff Goldsmith
Source: OECD, Our World in Data
Late last year, I saw this chart which made my heart sink. It compared US life expectancy to its health spending since 1970 vs. other countries. As you can see, the US began peeling off from the rest of the civilized world in the mid-1980’s. Then US life expectancy began falling around 2015, even as health spending continued to rise. We lost two more full years of life expectancy to COVID. By the end of 2022, the US had given up 26 years-worth of progress in life expecta...
Source: The Health Care Blog - October 9, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy COVID Drug Overdoses gun violence Hospitals Jeff Goldsmith Maternal mortality Mental Health Obesity Poverty Regional Economy Society Source Type: blogs
Fight Aging! Newsletter, October 9th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 8, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
