NIH Director's Seminar Series
NIH Directors Seminar Series Dr. Xu ’ s Laboratory of Molecular Genetics, Systems Biology Center, NHLBI is interested in the basic mechanism guiding the transmission of our second genome- mitochondrial DNA. Mutations in mitochondrial genome have emerged as important factors compromising human health. Although mitochondrial genome is prone to accumulating mutations due to the high spontaneous mutation frequency and a lack of repair mechanisms, the crippling mitochondrial mutation is exceedingly rare in populations. It is puzzling how mothers are able to restrict the transmission of damaging mutations to the next generatio...
Source: Videocast - All Events - October 9, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair: Mapping polymerase usage and the mutagenic consequences thereof
DNA Repair Interest Group videoconferenceAir date: 10/16/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - September 28, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair - Young Investigator Talks: (1) Leukemia-associated mutations in DNMT3A modify sensitivity to cytotoxic chemotherapy, (2) Regulation of BER Activities by Histone Acetylation, (3) DNA polymerase lambda in base excision DNA repair pathways
DNA Repair Interest Group videoconference Young Investigator TalksAir date: 9/11/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 17, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair – History of the repair of oxidative DNA damage
DNA Repair Interest Group videoconferenceAir date: 3/19/2019 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - August 17, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

LINGO proteins: a new language for the mucosal barrier
NIH Director ’ s Wednesday Afternoon Lecture Series The Herbert lab investigates cellular and molecular mechanisms responsible for the initiation of Type 2 immunity against gastrointestinal helminths and enteropathogenic bacteria. We are focused upon identification of novel cytokine/receptor interactions that regulate the cross-talk between epithelial and myeloid compartments leading to pathogen clearance and tissue repair.Air date: 6/21/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - June 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair Interest Group - A comprehensive repertoire of mutational signatures in human cancer
DNA Repair Interest Group videoconferenceAir date: 6/19/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair Interest Group - Repair-resistant Aristolochic acid-derived DNA adducts
DNA Repair Interest Group videoconferenceAir date: 5/15/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair Interest Group - ATR/Chk1 axis controls replication origin firing
DNA Repair Interest Group videoconferenceAir date: 4/24/2018 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - April 23, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Resolution of Inflammation
Immunonology IG Seminar A successful immune response involves the coordinated and sequential activation of host defense mechanisms, resolution of inflammation and restitutio ad integrum of the affected tissue. Macrophages are polyfunctional immune cells critical for initiation, resolution of inflammation, and consequent tissue repair. Upon damage, tissue-resident macrophages release inflammatory cytokines and chemokines, and recruit effectors such as neutrophils. Subsequently, macrophages at the damage site adopt a tissue repair profile. A set of diverse and unrelated cues has emerged as critical signals that induce the re...
Source: Videocast - All Events - February 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

LINGO proteins: a new language for the mucosal barrier
NIH Director's Wednesday Afternoon Lecture Series The Herbert lab investigates cellular and molecular mechanisms responsible for the initiation of Type 2 immunity against gastrointestinal helminths and enteropathogenic bacteria. We are focused upon identification of novel cytokine/receptor interactions that regulate the cross-talk between epithelial and myeloid compartments leading to pathogen clearance and tissue repair.For more information go tohttps://oir.nih.gov/wals/2017-2018/Air date: 3/21/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair
Interest Group videoconferenceAir date: 12/17/2019 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair
Interest Group videoconferenceAir date: 11/19/2019 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair
Interest Group videoconferenceAir date: 10/15/2019 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair
Interest Group videoconferenceAir date: 9/17/2019 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

DNA Repair
Interest Group videoconferenceAir date: 6/18/2019 12:30:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 30, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video