Case Report: Survival from Clinical Rabies in a Young Child from Maharashtra, India, 2022
Am J Trop Med Hyg. 2023 Oct 2:tpmd220683. doi: 10.4269/ajtmh.22-0683. Online ahead of print.ABSTRACTA 3.5-year-old male child from Maharashtra, India, presented with features of meningoencephalitis approximately 1 month after sustaining severe bite injuries on the right hand from a stray dog. He had received four doses of post-exposure intradermal rabies vaccination (on days 0, 3, and 7 of the bite and erroneously on day 20, instead of day 28 as recommended in the updated Thai Red Cross regimen) as well as local and systemic injections of equine rabies immune globulin. The child was initially diagnosed with and treated for...
Source: The American Journal of Tropical Medicine and Hygiene - October 2, 2023 Category: Tropical Medicine Authors: Padinjaremattathil Thankappan Ullas Chandhu Balachandran Nikhil Pathak Yadav Prasad Manikrao Shailesh Rathod Daya Vishal Pavitrakar Vijay Parashramji Bondre Priya Abraham Source Type: research
Case Report: Survival from Clinical Rabies in a Young Child from Maharashtra, India, 2022
Am J Trop Med Hyg. 2023 Oct 2:tpmd220683. doi: 10.4269/ajtmh.22-0683. Online ahead of print.ABSTRACTA 3.5-year-old male child from Maharashtra, India, presented with features of meningoencephalitis approximately 1 month after sustaining severe bite injuries on the right hand from a stray dog. He had received four doses of post-exposure intradermal rabies vaccination (on days 0, 3, and 7 of the bite and erroneously on day 20, instead of day 28 as recommended in the updated Thai Red Cross regimen) as well as local and systemic injections of equine rabies immune globulin. The child was initially diagnosed with and treated for...
Source: Am J Trop Med Hyg - October 2, 2023 Category: Infectious Diseases Authors: Padinjaremattathil Thankappan Ullas Chandhu Balachandran Nikhil Pathak Yadav Prasad Manikrao Shailesh Rathod Daya Vishal Pavitrakar Vijay Parashramji Bondre Priya Abraham Source Type: research
Viruses, Vol. 15, Pages 2040: Mathematical Modeling of Rhesus Cytomegalovirus Transplacental Transmission in Seronegative Rhesus Macaques
Cliburn Chan
Approximately 0.7% of infants are born with congenital cytomegalovirus (CMV), making it the most common congenital infection. About 1 in 5 congenitally infected babies will suffer long-term sequelae, including sensorineural deafness, intellectual disability, and epilepsy. CMV infection is highly species-dependent, and the rhesus CMV (RhCMV) infection of rhesus monkey fetuses is the only animal model that replicates essential features of congenital CMV (cCMV) infection in humans, including placental transmission, fetal disease, and fetal loss. Using experimental data from RhCMV seronegative rhesus macaque...
Source: Viruses - October 1, 2023 Category: Virology Authors: Yishu Gong Matilda Mostr öm Claire Otero Sarah Valencia Alice F. Tarantal Amitinder Kaur Sallie R. Permar Cliburn Chan Tags: Article Source Type: research
Atorvastatin/immune-globulin/methylprednisolone
(Source: Reactions Weekly)
Source: Reactions Weekly - October 1, 2023 Category: Drugs & Pharmacology Source Type: research
Immune-globulin
(Source: Reactions Weekly)
Source: Reactions Weekly - October 1, 2023 Category: Drugs & Pharmacology Source Type: research
Real-World Use, Safety, and Patient Experience of 20% Subcutaneous Immunoglobulin for Primary Immunodeficiency Diseases
CONCLUSION: The CORE study provides real-world evidence of the flexibility, feasibility, safety, and tolerability of Ig20Gly infusions, at mostly weekly intervals, over 1 year in patients with PIDs.TRIAL REGISTRATION: German Clinical Trials Register, DRKS00014562. Registered April 9, 2018, https://drks.de/search/en/trial/DRKS00014562.PMID:37751025 | DOI:10.1007/s12325-023-02649-0 (Source: Adv Data)
Source: Adv Data - September 26, 2023 Category: Epidemiology Authors: Maria Fasshauer Michael Borte Michaela Bitzenhofer Christine Pausch David Pittrow Michelle Park Andr é Gladiator Peter Jandus Source Type: research
Thrombocytopenia Associated with Elemental Mercury Poisoning in Two Siblings - Connecticut, July 2022
MMWR Morb Mortal Wkly Rep. 2023 Sep 22;72(38):1027-1031. doi: 10.15585/mmwr.mm7238a2.ABSTRACTTwo siblings aged 5 and 15 years from Connecticut were hospitalized with petechial rash, oral mucositis, and severe thrombocytopenia approximately 10 days after they played with a jar of elemental mercury they found in their home. Before the mercury exposure was disclosed, the siblings were treated with platelet transfusions, intravenous immune globulin (IVIG) for possible immune thrombocytopenic purpura, and antibiotics for possible infectious causes. When their conditions did not improve after 6 days, poison control facilitated f...
Source: MMWR Morb Mortal Wkl... - September 21, 2023 Category: Epidemiology Authors: Emily W Hogeland Tarah S Somers Luke Yip Suzanne Doyon Carrie A Redlich Andrea D Orsey Craig B Woda Suzannah T Swan Henry M Feder Source Type: research
Thrombocytopenia Associated with Elemental Mercury Poisoning in Two Siblings - Connecticut, July 2022
MMWR Morb Mortal Wkly Rep. 2023 Sep 22;72(38):1027-1031. doi: 10.15585/mmwr.mm7238a2.ABSTRACTTwo siblings aged 5 and 15 years from Connecticut were hospitalized with petechial rash, oral mucositis, and severe thrombocytopenia approximately 10 days after they played with a jar of elemental mercury they found in their home. Before the mercury exposure was disclosed, the siblings were treated with platelet transfusions, intravenous immune globulin (IVIG) for possible immune thrombocytopenic purpura, and antibiotics for possible infectious causes. When their conditions did not improve after 6 days, poison control facilitated f...
Source: MMWR Morb Mortal Wkl... - September 21, 2023 Category: Epidemiology Authors: Emily W Hogeland Tarah S Somers Luke Yip Suzanne Doyon Carrie A Redlich Andrea D Orsey Craig B Woda Suzannah T Swan Henry M Feder Source Type: research
Thrombocytopenia Associated with Elemental Mercury Poisoning in Two Siblings - Connecticut, July 2022
MMWR Morb Mortal Wkly Rep. 2023 Sep 22;72(38):1027-1031. doi: 10.15585/mmwr.mm7238a2.ABSTRACTTwo siblings aged 5 and 15 years from Connecticut were hospitalized with petechial rash, oral mucositis, and severe thrombocytopenia approximately 10 days after they played with a jar of elemental mercury they found in their home. Before the mercury exposure was disclosed, the siblings were treated with platelet transfusions, intravenous immune globulin (IVIG) for possible immune thrombocytopenic purpura, and antibiotics for possible infectious causes. When their conditions did not improve after 6 days, poison control facilitated f...
Source: MMWR Morb Mortal Wkl... - September 21, 2023 Category: Epidemiology Authors: Emily W Hogeland Tarah S Somers Luke Yip Suzanne Doyon Carrie A Redlich Andrea D Orsey Craig B Woda Suzannah T Swan Henry M Feder Source Type: research
Thrombocytopenia Associated with Elemental Mercury Poisoning in Two Siblings - Connecticut, July 2022
MMWR Morb Mortal Wkly Rep. 2023 Sep 22;72(38):1027-1031. doi: 10.15585/mmwr.mm7238a2.ABSTRACTTwo siblings aged 5 and 15 years from Connecticut were hospitalized with petechial rash, oral mucositis, and severe thrombocytopenia approximately 10 days after they played with a jar of elemental mercury they found in their home. Before the mercury exposure was disclosed, the siblings were treated with platelet transfusions, intravenous immune globulin (IVIG) for possible immune thrombocytopenic purpura, and antibiotics for possible infectious causes. When their conditions did not improve after 6 days, poison control facilitated f...
Source: MMWR Morb Mortal Wkl... - September 21, 2023 Category: Epidemiology Authors: Emily W Hogeland Tarah S Somers Luke Yip Suzanne Doyon Carrie A Redlich Andrea D Orsey Craig B Woda Suzannah T Swan Henry M Feder Source Type: research
Thrombocytopenia Associated with Elemental Mercury Poisoning in Two Siblings - Connecticut, July 2022
MMWR Morb Mortal Wkly Rep. 2023 Sep 22;72(38):1027-1031. doi: 10.15585/mmwr.mm7238a2.ABSTRACTTwo siblings aged 5 and 15 years from Connecticut were hospitalized with petechial rash, oral mucositis, and severe thrombocytopenia approximately 10 days after they played with a jar of elemental mercury they found in their home. Before the mercury exposure was disclosed, the siblings were treated with platelet transfusions, intravenous immune globulin (IVIG) for possible immune thrombocytopenic purpura, and antibiotics for possible infectious causes. When their conditions did not improve after 6 days, poison control facilitated f...
Source: MMWR Morb Mortal Wkl... - September 21, 2023 Category: Epidemiology Authors: Emily W Hogeland Tarah S Somers Luke Yip Suzanne Doyon Carrie A Redlich Andrea D Orsey Craig B Woda Suzannah T Swan Henry M Feder Source Type: research
Thrombocytopenia Associated with Elemental Mercury Poisoning in Two Siblings - Connecticut, July 2022
MMWR Morb Mortal Wkly Rep. 2023 Sep 22;72(38):1027-1031. doi: 10.15585/mmwr.mm7238a2.ABSTRACTTwo siblings aged 5 and 15 years from Connecticut were hospitalized with petechial rash, oral mucositis, and severe thrombocytopenia approximately 10 days after they played with a jar of elemental mercury they found in their home. Before the mercury exposure was disclosed, the siblings were treated with platelet transfusions, intravenous immune globulin (IVIG) for possible immune thrombocytopenic purpura, and antibiotics for possible infectious causes. When their conditions did not improve after 6 days, poison control facilitated f...
Source: MMWR Morb Mortal Wkl... - September 21, 2023 Category: Epidemiology Authors: Emily W Hogeland Tarah S Somers Luke Yip Suzanne Doyon Carrie A Redlich Andrea D Orsey Craig B Woda Suzannah T Swan Henry M Feder Source Type: research
The benefit of intravenous immune globulin in the treatment of delayed radiation myelopathy
AbstractDelayed radiation myelopathy (DRM) is a rare yet severe complication of radiotherapy. This condition has a progressive pattern that is often irreversible. Several therapeutic strategies have been introduced to alleviate disease complications, including corticosteroids, hyperbaric oxygen, anticoagulants, and antivascular endothelial gro wth factor (VEGF) agents. However, despite their beneficial effect, they have not been the definitive treatments for DRM. Here we present the case of a 55-year-old woman with a history of multiple myeloma who developed neurological complications 11 months after radiation therap...
Source: Strahlentherapie und Onkologie - September 19, 2023 Category: Cancer & Oncology Source Type: research
